examples of mutations in human genes that affect the phenotype?

Answers

Answer 1

Answer: Sickle-cell Anemia, Beta hemoglobin (beta globin)

Explanation: For example, sickle-cell anemia is a disease caused by the smallest of genetic changes. Here, the alteration of a single nucleotide in the gene for the beta chain of the hemoglobin protein (the oxygen-carrying protein that makes blood red) is all it takes to turn a normal hemoglobin gene into a sickle-cell hemoglobin gene. This single nucleotide change alters only one amino acid in the protein chain, but the results are devastating.

Beta hemoglobin (beta globin) is a single chain of 147 amino acids. As previously mentioned, in sickle-cell anemia, the gene for beta globin is mutated. The resulting protein still consists of 147 amino acids, but because of the single-base mutation, the sixth amino acid in the chain is valine, rather than glutamic acid.

Answer 2

Sickle-cell anemia is an example of a mutation in the beta-globin gene that changes the phenotype of a red blood cell.

What is Mutation?

Genetic alterations might result in a condition like sickle-cell anemia. Here, a normal hemoglobin gene may be converted into a sickle-cell hemoglobin gene by changing a single nucleotide in the gene encoding the beta chain of the hemoglobin.

A single chain of 147 amino acids makes up beta-globin, often known as beta-hemoglobin. The beta-globin gene is mutated in sickle-cell anemia, as was already noted.

The resultant protein still has 147 amino acids, but due to the single-base mutation, valine rather than glutamic acid makes up the sixth amino acid in the chain.

Therefore, only one amino acid in the protein chain is altered by this one nucleotide mutation, but the consequences are disastrous.

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Related Questions

What are 2 major concerns about copper mining?

Answers

Answer:

Land degradation. Increased deforestation. Water and air pollution from particles of sulphuric acid, which severely affect those residing near mines.

hope this helps and please give brainliest!

These include taxes and royalties, relations with workers, local communities and environmental groups, resource nationalism, and political and legal instability. In that respect, the problems in the copper industry are like those that have held back oil production outside North America.

Gases in the air that are present in very small amounts are called ______
gasses.

Answers

Answer:

trace

Explanation:

What are homologous chromosomes?

Answers

Answer:

A couple of homologous chromosomes, or homologs, are a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization.

Explanation:

Answer:

A couple of homologous chromosomes, or homologs, are a set of one maternal and one paternal chromosome that pair up with each other inside a cell during fertilization.

Hope this helps. Can u give me brainliest

Explanation:

Need answer quick pls

Answers

Answer:

b

Explanation:

Yeah I think the answer is B

Can someone answer this quick



15 pts

Answers

Answer:

cheery and Tuesday kuphela kukhona e show yami i can't wait

Answer:

the correct answer is number 3 ( vegetative propagation)

Which of the following structures help the cell remove wastes:

A: Vesicles
B: Mitochondria
C: Golgi Complex
D: Endoplasmic Reticulum

Answers

Answer:

Vesicles help the cell remove wastes

Answer:

Lysosomes break down waste products within the cell and transport the remains out of the cell. They contain enzymes that help them do this.

Explanation:

i hope you understand

I needhelp with this plzzz

Answers

Answer:

you just need to create a hypothesis using the scientific enquiry and then put a fluid and try to find out the answer.

what genotype would puppies have if two labradoodles were bred together?



PLZ I NEED HELP!!! ITS IMPORTANT!

Answers

Answer:

The answer is heterozygous

Answer: depends on what the dna is. For sure they’ll be hetrodyus

Explanation:

Why are their different tissues in a sheep heart

Answers

That’s because they are different from other living things

Which of the following best explains why cells that contain the same genetic material do not develop into the same types of cells?
A. Because chemical signals that are released during the cell cycle can result in the linking of similar genes
B. Because internal or external stimuli can trigger the activation of specific genes in the DNA of cells
C. Because messenger RNA is converted to transfer RNA when cell differentiaton begins
D. Because random mutations can occur in the DNA of cells during early embryonic development ​

Answers

The statement 'internal or external stimuli trigger the activation of specific genes in the DNA of cells' BEST explains why cells having the same genetic material do not develop into the same cells (Option B).

Cell specialization refers to the process by which common stem cells differentiate to produce specialized cells that perform specific functions.

Cell specialization is caused by differential gene expression patterns that lead to the expression of different proteins in different types of cells.

For example, hematopoietic stem cells differentiate into red blood cells to transport oxygen in the blood by expressing the hemoglobin gene, whose protein binds to oxygen.

In conclusion, the statement 'internal or external stimuli trigger the activation of specific genes in the DNA of cells' BEST explains why cells having the same genetic material do not develop into the same cells (Option B).

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Y’all I need help!!

Answers

Answer:

The answer is C.

Explanation:

If its wrong please blame me.


Need help with 15 and 16 too

Answers

Answer:

15. C anaerobic respiration

16. D photosynthesis, in which carbon dioxide is used and sugars are produced

Question 3
Which of the following is not a phase change that can occur when water absorbs heat?

a
evaporation
b
sublimation
c
condensation
d
melting

Answers

Answer:

C

Explanation:

The condensation is the opposite process of evaporation. And we know that when water absorbs heat evaporation, melting, and sublimation all occur. Leading us to conlude that condensation is not a phase change that can occur when water absorbs heat.

Helppppp please What characteristic of water
means that clear water is not
necessarily clean water?
A. the density of the water
B. high specific heat capacity
C. the temperature of the water
D. ability to act as a universal solvent

Answers

Answer:

B

Explanation:

Ability of water to act as a universal solvent means that clear water is not necessarily clean water. Therefore, option (D) is correct.

What is clean water?

Clean, safe water is defined by the USGS as "water that won't hurt you if you come in touch with it." Although drinking water is often mentioned when discussing clean water, clean water is also crucial for all residential uses.

It is impossible to smell, taste, or even see the microscopic contaminants that pollute water, such as bacteria, viruses, and parasites. Therefore, just because your water is clear doesn't imply it's okay to drink.

Therefore,  due to the fact that water is a universal solvent, meaning that it is capable of dissolving a wide range of substances with relative ease clear water is not considered clean.

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What do the components of the skeletal system allow a
person to do?

Answers

The skeletal system works as a support structure for your body. It gives the body its shape, allows movement, makes blood cells, provides protection for organs and stores minerals.

5. Some bacteria are ___
meaning they eat other organisms, and some are ___
meaning they make their own food.

A) Heterotrophs, Photosynthetic

B) Autotrophs, Heterotrophs

C) Autotrophs, Photosynthetic

D) Heterotrophs, Autotrophs

Answers

Answer:

D, 'cus Heterotrophs can't make their own food like plants or humans, and Autotrophs can make their own food. For example plants, or in this case bacteria

Answer:

D

Explanation

Heterotrophs are organisms that eat other organisms for energy and nutrients

Autotrphs produce their own food with the help of photosynthesis

Hope This Helps :)

Some students used vinegar to dissolve away the shells of three eggs and used these eggs as models of human red blood cells. The students observed
the changes in the eggs when they were placed in different solutions.
Which statement best describes the role of the cell membrane in this model?

Answers

Answer:

the cell membrane is permeable and allows to enter and leave

Explanation:

Answer:

the cell membrane allows water to enter and leave the cell

Explanation:

A punnet square is used to determine what?

Answers

Answer:

predict genotypes

Explanation:

Answer: genotype

Explanation: A Punnett Square is a helpful tool that helps to predict the variations and probabilities that can come from cross-breeding. This includes predicting crossing plants, animals, and even humans with each other.

1. How does deforestation affect the amount of carbon dioxide in the
atmosphere?

Answers

deforestation affects the amount of carbon dioxide in the atmosphere because trees hold carbon dioxide and if they are being taken away the carbon dioxide levels drop

______ help blood clot following wounds, so that wounds stop bleeding.

Answers

Applying ice to a wound will constrict the blood vessels, allowing a clot to form more quickly and stop the bleeding. The best way to do this is to wrap ice in a clean, dry cloth and place it on the wound

I think the ice will help the blood clot which will help the wound stop bleeding.

List 3 examples of nutritional and hormonal factors that bone development depends on

Answers

Answer:

 

Explanation:

Answer:

vitimins D,C, and b

Explanation:


Where are volcanoes
generally formed?

A. "Hot spots," transform boundaries,
convergent boundaries

B. At all plate boundaries

C. "Hot spots," divergent boundaries,
convergent boundaries

5. "Hot spots," divergent boundaries,
transform boundaries

Answers

Answer:

Most of the Earth's igneous rocks are produced at the "Ring of Fire." ... Volcanic activity occurs at two types of plate boundaries: mid-ocean ridges and ... Recall that there are three types of plate boundaries: convergent, divergent, and transform. ... The map below shows several hot spots, but not all the existing ones

Explanation:

what is role of degenerating corpus luteum if fertilisation takes place in the Fallopian tube?​

Answers

Explanation:

the main purpose of the corpus luteum is that it pulses out hormones, including progesterone. But if the egg isn't fertilised, the corpus luteum stops secreting progesterone.

Which ones are connected and how are they connected

Answers

Hydrogen, water, oxygen because hydrogen and oxygen make water. Electrons, neutrons, protons. Atoms make up a molecule so those two would probably go together

What are regions of DNA that code for proteins called?

a. Primers
b. Anticodons
c. Genes
d. Promoters

Answers

Answer:

C - Genes

Explanation:

Hope this helps :)

Which is an example of energy moving an object from place to place?
O water in a bowl
O wind blowing a grain of sand
O a batter ready to hit a baseball
O a drummer rady to hit a drum

Answers

Answer:

B, wind blowing a grain of sand

Explanation:

it is the only answer where something is moving, the others are not moving

Answer:the answer to you question is why

Explanation:

The number of different species and the number of individual organisms describes...

A. An ecosystem

B. The biome

C. The biodiversity

Answers

The number of different species and the number of individual organisms describes the biodiversity

HELLPPPPP please!!!!

Answers

Answer:

D

Explanation:

because it shows if the child will have a dominant trait from a parent or a recessive trait, which you can also find out what color eyes, hair, etc, your child will be born with.

a football plyer throws a ball with a mass of 0.34kg what is the gravitational potential energy of the ball when it is 5.0 m above the ground?

Answers

Answer:

17 J

Explanation:

PE=mgh=0.34x10x5=17

The potential energy is defined as the energy that is present in a resting body. It is 17J.

What is the other form of energy in any moving objects ?

It is the kinetic energy that is present in the moving objects. It is just possessed by the moving objects.  

PE= mgh where m stands for the mass of a body where it is the matter that is contained inside a container, g stands for the gravity under which effect the body comes down back to the Earth which has value of 9.8 and h is the height that is the distance covered by the body in the vertical manner.

When 0.34 is multiplied with 9.8 and 5.0 the answer is 17 J that is the energy that is possessed by the resting body which is not undergoing any kind of motion and not going through any kind of disturbance in the motion.

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fill in the blanks in the paragraph below using the word bank provided.

Answers

Answer:

In natural selection, organims that are well suited for their environment tend to survive and reproduce. WHen organisms reproduce, they pass their characterisitcs on to their offspring through their genes. Organisms with characters not well suited for their environment are not as likely to survive to reproduce and pass on their characteristics. Organisms that are not able to reproduce and pass on their traits to their offspring die off, or become extinct.

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