During exercise, protein synthesis in muscle cells stops. After exercise, protein synthesis starts again and contributes to the growth of muscle caused by exercise. A study by Dreyer et al found that the protein 4E-BP1 is normally phosphorylated in muscle cells, but becomes dephosphorylated during exercise and phosphorylated again after exercise. The dephosphorylated form of 4E-BP1 can bind to elF4E to block its normal function. How might 4E-BP1 block protein synthesis during exercise?
A. 4E-BP1 binding to elF4E prevents release factors from binding to the A site of the ribosome.
B. 4E-BP1 binding to elF4E blocks the function of EF-Tu.
C. 4E-BP1 binding to elF4E makes the ribosome too big to translocate along the mRNA
D. 4E-BP1 binding to elF4E prevents loading of the mRNA onto the ribosome.

Answers

Answer 1

Answer:

D. 4E-BP1 binding to elF4E prevents loading of the mRNA onto the ribosome.

Explanation

In eukaryotic organisms, the eIF4E translation initiation factor functions by directing the ribosomes to the 5'-terminal cap structure of the messenger RNA (mRNA) in order to start the translation. Moreover, phosphorylation is a posttranslational modification of specific amino acids on proteins that play diverse cellular functions by altering protein stability, location, and/or enzymatic activity. It has been shown that elF4E phosphorylation is increased in response to cellular stimuli that induce translation in the ribosomes (e.g., growth factors, hormones, etc). The eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1) is a repressor of mRNA translation which is phosphorylated and inactivated by growth factors and hormones, thereby inhibiting 4E-BP1 binding to elF4E and consequently activating translation.


Related Questions

An area of grassland is transitioning into a desert due to overgrazing of livestock. What will happen to the population of grass eating
native organisms in the area?
O A. The population will increase.
OB. The population will decrease.
C. The population will experience no change.
D. The population will decrease, then slowly increase.

Answers

Answer:A

Explanation:

Because n

Answer:the answer is B.the population will decrease.

Explanation:

The population will decrease because since the grassland is turning into a desert due to overgrazing, it will be causing the grass to die out, and since the grass is dying out, the grass eating native organisms population will start to go down as well because there will be no more grass to eat from, so therefore i think the answer is B. The population will decrease.

I hope this helps :3

Can mutations occur on tRNA?

Answers

Pathological mutations in tRNA genes and tRNA processing enzymes are numerous and result in very complicated clinical phenotypes.

How is carbon transferred to the soil ?

Answers

Answer:

I'm not 100% sure but my beat bet is: Carbon moves from plants and animals to soils

Answer:

On grazed land, cattle trample some of the plants into the soil increasing carbon content. In forested areas, dead plant material is incorporated into the soil by worms and other soil organisms. On cropped land, it doesn't very much, causing soil degradation.

Explanation:

Credit to Alan Willoughby, former Maths Teacher, Earth Scientist, Natural Therapist, (1974-2018) for the answer

Give an example of how energy transformations are involved in the development of an energy source.

Answers

Answer:

Energy transformations are processes that convert energy from one type (e.g., kinetic, gravitational potential, chemical energy) into another. Any type of energy use must involve some sort of energy transformation.

Energy must obey the laws of thermodynamics.

Thermodynamics is the study of how energy changes from one type to another. The laws of thermodynamics apply to energy and energy conversions.

Explanation:

hope it help to you

1. Within food chains, matter is
a) constantly increasing
b) constandy decreasing
c) always changing from one element to another
d) alavays recycled from one chemical form into
another

Answers

Answer:

C

Explanation:

When an organism eats anothee organism matter transfers

Question 5
What makes some individuals more likely to survive and have offspring

Answers

Answer:

can adapt to environment, access to food, ability to mate and reproduce

Explanation:

yea this should be right

1. One reason for controlling which genes are expressed in multicellular organisms is that

a. different cells have different functions so they need different proteins.

b. we need all proteins made in every type of cell.

c. we need cells made all the time.

d. not every cell needs amino acids.

e. none of the above​

Answers

I think it is c because it is the most important

URGENT PLS ANSWER ASAP!!! 50 POINTS fill out the punnet square!

Answers

Answer:

I don't even know what this is, I need more information

Which of the following terms refers to the commercial production of decorative plants and flowers?
A. horticulture
B. pomology
C. botany
D. floriculture

*its D*

Answers

Answer:

d

Explanation:


NEED HELP ASAPPPPP!!! PLSSS

Answers

here ya go! It wouldn’t let me submit for some odd reason so I just took a screenshot and am uploading that instead. good luck!

PLS HURRY
Why are there seasons?

A.Earth's axis is tilted.

B.Earth rotates on its axis.

C.Earth revolves around the sun.

D.The moon revolves around Earth.

Answers

B. Earth rotates on a tilted axis

The seasons are created by the differences in proximity to the sun from the earth being tilted towards or away from the sun.

Answer:

Earth's axis is tilted.

Explanation:

What are the relationships between an organism and its environment?

Answers

Sorry cant help and dont hit the link its a virus

What was the first known society?"
Post Industrial
Industrial
Agriculture
Hunting and Gathering

Answers

Answer:

Hunting and Gathering

Explanation:

The first humans were nomads who traveled with their food. This means that they would seasonally move across regions hunting the animals there and gathering plants to eat. These people existed before civilization started. Centuries later, these people would develop agriculture and start society. However, the first people were still hunter-gathers.

The flocks all started with 10 birds. Flock
was the most successful at feeding, so it will have the greatest number in the second generation. Flock
was the least successful at feeding and has shrunk the most.

Answers

In this scenario, natural selection is affecting many populations of birds with different beak morphologies, which affects how well they can eat the available foods. Each flock initially consisted of 10 birds, but over many generations, natural selection favored some traits over others, changing the population size.

One flock, referred to as "Flock," had the greatest number of second-generation birds because it was the most successful at feeding. Another flock, known as "Flock," had the worst feeding results and has had the greatest shrinkage.

Learn more about Natural selection, here:

https://brainly.com/question/2725702

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Your question is incomplete, most probably the complete question is:

The flocks all started with 10 birds. Flock was the most successful at feeding, so it will have the greatest number in the second generation. Flock was the least successful at feeding and has shrunk the most. With three foods available, natural selection has favored Flock , which has increased the most in the first three generations. Meanwhile, Flock has declined the most because its beak was the least successful phenotype for the food available.

What provides energy to muscles and helps keep
them strong?

Answers

Answer:

The source of energy that is used to power the movement of contraction in working muscles is adenosine triphosphate (ATP) – the body's biochemical way to store and transport energy. However, ATP is not stored to a great extent in cells. So once muscle contraction starts, the making of more ATP must start quickly.

Answer:

adenosine triphosphate (ATP)

Explanation:

Creatine phosphate can supply the energy needs of a working muscle at a very high rate, but only for about 8–10 seconds.

¿cual es la impoortancia de la fotosintesis para la vida en la tierra?

Answers

Answer:

La respuesta está en la explicación. Espero que sea útil.

Explanation:

La fotosíntesis es importante para los organismos vivos porque es la principal fuente de oxígeno en la atmósfera. Sin la fotosíntesis, el ciclo del carbono no podría producirse, la vida que requiere oxígeno no sobreviviría y las plantas morirían.

Si lo he entendido mal, pido disculpas. También estoy utilizando un traductor, por lo que puede ser incorrecto.

What is the independent variable
What is the dependent variable
What is the conclusion to this graph

Please don’t send the link that hacks you, respond as a troll, or just comment and then delete your account afterwards

It’s real Tiring.

Answers

Answer:

Independent variable = time (in centuries)

Dependent variable = Percentage of all people in poverty

The conclusion: As centuries progressed, the percentage of all people in poverty decreased

Please give brainliest if you are happy with my answer :)

What is the importance of knowing cranium size, dentition, number of toes/fingers, flexibility of joints, locomotion styles, body size, the skeleton, etc. Of primates?

Answers

Answer:

Important for identification.

Explanation:

Knowing the cranium size, dentition, number of toes/fingers, flexibility of joints, locomotion styles, body size, the skeleton, etc. of primates is very important to identify the specie of primates group. Different primates have different cranium size, dentition, fingers or toe's number, flexibility of joints, locomotion styles, body size, the skeleton etc so these information helps in identification and grouping of primates during classification.

The _____ is the primary channel for the transportation of water, mineral and food from the roots and leaves to the rest of the plant

Answers

Answer:

Xylem

Explanation:

Xylem is one of the vascular tissues or conducting tissues in plants. It primary function is to transport water, solutes, minerals, from the plants root and leaves to the rest of the plants. It also provide physical support to the plants and it consist of specialised vessels that contain tissues called tracheary elements.

26. Which equation is NOT balanced?
a. 4H, +202 + 4H2O
b. H2 + H2 + O2 -> H2O + H2O
c. 2H2 + O2 -> 2H2O
d. 2H2 + O2 + H2O

Answers

Answer:d. 2H2 + O2 -> H2O

Explanation:

10 points for each answer, I'm not afraid to report. The graph is shown in the picture.
The table below shows the average monthly temperatures of four locations.
Based on the table, which of these locations is most likely situated near the ocean? (4 points)
Location A
Location B
Location C
Location D

Answers

Answer:

Location A

Explanation:

Coastal areas have milder temperatures since they are close to water and water retains heat better than land (it's harder to warm it up and harder to cool it down). Due to this property of water, the location with the least temperature fluctuation would be the answer. Location A has the smallest range between the highest and lowest annual temperatures, making A the best answer choice. I hope I helped and that it's not too late for you.

SC.6.P.11.1 n s 11. Which of the following describes the law of conservation of energy? A. Energy cannot be created or destroyed. B. Energy can only be released through transformation. C. When energy is conserved, it always changes form. D. Energy increases when it is transferred from one object to another. n.​

Answers

Answer:

A. Energy cannot be created or destroyed

Explanation:

I answered the closest to the correct choice

Reasons why the queen is the most important in the hive.
(No LINK)

Answers

Answer:

I assume you are referring to bees?

Explanation:

From what I know and this is just surface level knowledge, she is the one who births the hive and usually designates their purpose once she has laid the eggs. She herself does not do much, she is just the one that the infrastructure of the hive follows in maintaining the hive itself. I hope this helps. Good luck!

The Queen Bee plays a vital role in the hive because she is the only female with fully developed ovaries. The queen's two primary purposes are to produce chemical scents that help regulate the unity of the colony and to lay lots of eggs.

Why would blood volume play a role in the amount of time a mammal can stay under water?

Answers

Answer:

The answer is that they store oxygen in their blood, and in their muscles rather than in their lungs. Marine mammals have a very high blood to body volume ratio. The mammalian diving reflex allows mammals to lower their heart rate and ultimately survive submersion in water for extended periods of time.

Explanation:

The reason why blood volume played a vital role should be explained below.

Role of blood volume:

In the case when the oxygen is stored in the blood & in their muscles instead of their lungs so this represents the role of blood volume. Also, marine mammals contain a high blood-to-body volume ratio. It permits the mammals for lowering the rate of heart and survive the submersion in the water for extension of the time. This is the main reason.

Learn more about volume here: https://brainly.com/question/13707148

According to the law of supply and demand, if the demand for a product suddenly goes up faster than the supply, which of the following will be the result?

Question 11 options:

The price of the product will go up.


The price of the product will go down.


Production of the product will decrease.


The price will reflect the cost of production.

Answers

Answer:

It is A, I believe .

Explanation:

More people want the product so business needs to boom. You need more money to produce the product, and to obtain more money for the product, you need to raise the price of the product. Hope this helps you!

Haploid cells are formed during??

a.) mitosis
b.) meiosis
c.) both meiosis and mitosis
d.) neither meiosis and mitosis

Answers

Answer:

B) meiosis

I hope that helped

c.) both meiosis and mitosis

When a haploid cell undergoes mitosis, it produces two haploid daughter cells.

Which statement is best supported by the data on the map?
A. All countries have beryllium deposits, but some have more
deposits than others.
B. Some countries have many sources of beryllium, and some have
no sources of beryllium.
C. All the beryllium used in the United States must come from other
countries.
D. Only people in countries that have beryllium deposits are able to
have cell phones.

Answers

Answer:

B. Some countries have many sources of beryllium, and some have no sources of beryllium.

Explanation:

Beryllium is a very important mineral that is present in many countries. All countries did not have beryllium deposits. Some countries have many sources and deposits of beryllium, and some have  no sources of beryllium. There are many deposits of beryllium in different parts of United states of America. Those countries which have no beryllium deposits have cell phones because they purchase cell phones from international market by paying money which can be earned through selling of its goods.

WILLL GIVE BRAINLISTTT!!! Why are scientists rethinking where life might be found?

Answers

Answer:

Cause they are always making up theroies and have no clue what is real and what is not, and they think the world is made my science so there has to be other plantes like earth since it was made there has to be others

Use insulin and glucagon as examples, explain how negative feedback of these two hormones regulate the blood glucose level and maintains homeostasis. (No links or I'll Report

Answers

Answer:

glucagon works to counterbalance the effects of insulin.

Explanation:

when insulin is released, the blood sugar in the body decreases; however, when the blood sugar is low enough, the system instead releases glucagon which breaks down the stored sugar and balances the blood sugar level in the body. if the level goes too high then insulin will be released again.

Exponential population growth happens when: Select all that apply.
There are no sufficient minerals.
There are too many predators.
There are plenty of resources.
No predators are present.
There are no resources.

Answers

Answer:

There are plenty of resources.

No predators are present.

Explanation:

There r plenty of resources + no predators

Exponential population growth happens when there are plenty of resources and no predators are present.

What do you mean by Population growth?

Population growth may be defined as the change in population per unit of time.

Exponential growth occurs in the population of continuous breeders. For example, some insects, humans, bacteria, etc.

Exponential population growth requires an enormous amount of resources in habitat and no predator influence.

Therefore, exponential population growth happens when there are plenty of resources and no predators are present.

To learn more about Exponential growth, refer to the link:

https://brainly.com/question/13567225

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