El desarrollo de la endocarditis infecciosa puede estar relacionado con enfermedades infecciosas, especialmente aquellas causadas por bacterias.
La endocarditis infecciosa (IEC), también conocida como endocarditis infecciosa, es una infección grave de la capa interna del corazón o de las valvulas cardíacas. Muchos factores de riesgo contribuyen al desarrollo de IEC, y de las opciones ofrecidas, todos son reconocidos como factores de riesgo para esta condición.Los procedimientos dentales, como las cirugías dentales invasivas o las cirugías orales, pueden introducir bacterias en el flujo sanguíneo, lo que puede llegar al corazón y causar una enfermedad en el endocardio o los valvularios del corazón.Compared to native heart valves, prosthetic heart valves are more susceptible to IEC. La presencia de materiales artificiales crea una superficie a la que las bacterias pueden agarrar y formar biofilm, lo que aumenta la probabilidad de infección.Las enfermedades infecciosas, especialmente las relacionadas con la presencia de bacterias
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Due to the self-complementarity of DNA, every strand can result in hairpin formations. A hairpin structure is produced when a single strand curls back on itself to form a stem-loop shape.
This structure is stabilised by hydrogen bonds established between complementary nucleotides in the same strand.A DNA structure is referred to as "cruciform" when two hairpin configurations inside the same DNA molecule line up in an antiparallel way. Frequently, cruciform formations are associated with palindromic sequences, which are DNA sequences that read identically on both strands when the directionality is disregarded.
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6 1 point Choose the following options which indicate pleiotropy: A mutant allele at one locus X creates mice with brown fur, while an allele at locus Y creates mice with red eye color. When mice are
The options that indicate pleiotropy in this scenario are: "A mutant allele at one locus X creates mice with brown fur" and "an allele at locus Y creates mice with red eye color."
Pleiotropy refers to a genetic phenomenon where a single gene or allele influences multiple, seemingly unrelated traits or phenotypes. In the given scenario, the following options indicate pleiotropy:
"A mutant allele at one locus X creates mice with brown fur."This suggests that a mutation at locus X affects both the color of the mouse's fur and potentially other traits."An allele at locus Y creates mice with red eye color."This indicates that an allele at locus Y influences the color of the mouse's eyes, which is a distinct trait from the fur color affected by locus X.By having different alleles at these loci (X and Y), the mice exhibit different phenotypes for both fur color and eye color. This demonstrates the concept of pleiotropy, where a single gene or allele can have multiple effects on the organism's traits.
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1. Briefly what is the function of cytotoxic t cells in cell-mediated immunity ?
2. Why are only high risk events infect HIV postive people while other events like skin to skin comtact does not infect them?
1.Casual contact with an HIV-positive person like shaking hands, hugging, or using the same toilet seat does not increase the risk of HIV transmission.
2.HIV (Human Immunodeficiency Virus) is primarily transmitted through specific routes, regardless of whether a person is considered high risk or not.
1. Function of cytotoxic T cells in cell-mediated immunity: Cytotoxic T cells (CTLs) or CD8+ T cells are a type of T lymphocyte that contributes to cell-mediated immunity by destroying virus-infected cells, tumor cells, and cells infected by other intracellular pathogens. They can target and kill these cells with the help of MHC-I molecules present on the surface of these infected cells.Cytotoxic T cells recognize and bind to antigenic peptides presented by major histocompatibility complex (MHC) class I molecules.
Once activated, these cells release cytokines that help activate other immune cells like macrophages, dendritic cells, and natural killer cells. They also secrete a protein called perforin, which forms pores in the target cell membrane, leading to cell lysis.2. High risk events infect HIV positive people while other events like skin to skin contact does not infect them because:HIV can be transmitted through bodily fluids, including blood, semen, vaginal fluids, and breast milk. High-risk events like unprotected sex, sharing needles or syringes for drug use, or mother-to-child transmission during pregnancy, delivery, or breastfeeding increase the chances of exposure to HIV.
Skin-to-skin contact, on the other hand, does not involve the exchange of bodily fluids, and therefore, the risk of HIV transmission through this route is negligible.HIV is a fragile virus that cannot survive outside the body for a long time. Therefore, casual contact with an HIV-positive person like shaking hands, hugging, or using the same toilet seat does not increase the risk of HIV transmission. HIV can only be transmitted when there is an exchange of bodily fluids containing the virus.
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Which statement below best describes a characteristic of an Alu
element?
a.Alu is typically transcribed by RNA pol III.
b.Alu is reverse transribed by L1 ORF1p.
c. Alu is an autonomous retrotransposon
Among the given statement, the best statement that describes a characteristic of an Alu element is "Alu is typically transcribed by RNA pol III."
Alu is the short interspersed nuclear element, which is 300 bp in length and is the most common repetitive element found in the human genome. Alu is classified under the group of retrotransposons, which are genetic elements that can move from one location to another location in the genome. Retrotransposons are the significant contributor to the genomic diversity of mammals.
Transcription of Alu elements, Alu elements are transcribed by RNA polymerase III (Pol III). RNA Pol III is a large complex enzyme that is responsible for the transcription of tRNAs, 5S rRNA, and other small untranslated RNA molecules.Alu elements are transcribed as RNA molecules, and these RNA molecules are the primary source of various small RNA molecules found in cells. After transcription, Alu RNA molecules fold back on themselves and form a hairpin structure that is stabilized by base pairing. These hairpin structures are recognized by the RNA-processing machinery, which cleaves them into small RNA molecules called Alu RNAs. Therefore, the correct statement among the given statement is "Alu is typically transcribed by RNA pol III."
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Suppose study looked at smoking (yes/no) as an exposure and CHD (yes/no) as outcome, and found a relative risk of 2.15. Which of the following is the correct interpretation of the RR? Smoking increases the risk of CHD by 2.15 The risk of CHD among smokers is 2.15 time the risk of non-smokers_ The risk among smokers is 2.15 higher than non-smokers_ The risk of CHD among non-smokers is half that of smokers
The correct interpretation of the RR is: Smoking increases the risk of CHD by 2.15. Hence Option Smoking increases the risk of CHD by 2.15 is correct.
Suppose a study looked at smoking (yes/no) as an exposure and CHD (yes/no) as outcome, and found a relative risk of 2.15. The correct interpretation of the RR is: Smoking increases the risk of CHD by 2.15.Relative risk (RR) is a measure of the strength of the association between an exposure and an outcome. In this case, smoking (exposure) and CHD (outcome) are being measured. When the RR is greater than 1, it suggests that the exposure is associated with an increased risk of the outcome.
If the RR is less than 1, the exposure is associated with a reduced risk of the outcome. If the RR is equal to 1, it suggests that the exposure is not associated with either an increased or reduced risk of the outcome.Here, the relative risk of 2.15 suggests that the risk of CHD is 2.15 times higher among smokers than non-smokers. Therefore, the correct interpretation of the RR is "Smoking increases the risk of CHD by 2.15".
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Which of the following statements about viruses is FALSE? Viruses have a nucleus but no cytoplasm. а Viruses can reproduce only when they are inside a living host cell. Viruses cannot make proteins on their own. Some viruses use RNA rather than DNA as their genetic material.
The option that is untrue of the ones offered is "Viruses have a nucleus but no cytoplasm."
Acellular infectious organisms with a fairly straightforward structure are viruses. They are made up of genetic material, either DNA or RNA, that is encased in a protein shell called a capsid. A virus's outer envelope may potentially be derived from the membrane of the host cell.However, biological organelles like a nucleus or cytoplasm are absent in viruses. They lack the equipment needed to synthesise proteins or carry out autonomous metabolic processes. In place of doing these things themselves, viruses rely on host cells.
The remaining assertions made are accurate:
- Only when a virus is inside a living host cell can it proliferate. They use the host cell's biological machinery to stealthily copy their genetic material.
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