Insulin is a hormone. It regulates how much sugar is in your blood. An elevated level of sugar in blood can induce issues in various parts of your body, which includes heart, kidney, eyes, and brain. also leads to kidney disease and kidney failure.
What happens when insulin is inhibited?Usually insulin provides the storage of glucose as glycogen in the liver. With a lack of insulin, there is both risen liver glucose level through raised glycogenolysis and gluconeogenesis also decline glucose use. The result is hyperglycemia.
Thus no dosage adjustment would be required upto 50%.
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Describe two problems/malfunctions that can occur in this feedback
loop that cause an imbalance of blood glucose levels and lead to
diabetes.
Answer:
People with type 1 diabetes do not produce insulin due to auto-immune destruction of the insulin producing cells, while people with type 2 diabetes have chronic high blood glucose levels that cause insulin resistance. With diabetes, blood glucose is increased by normal glucagon activity, but the lack of or resistance to insulin means that blood sugar levels are unable to return to normal. This causes metabolic changes that result in diabetes symptoms like weakened blood vessels and frequent urination. Diabetes is normally treated with insulin injections, which replaces the missing negative feedback of normal insulin secretions.
Explanation: