Suresh and Gail are students in a lab working on mice with defects in the function of the HOX3A gene. In the special mouse line they are working on, no sequence changes are present in the genomic DNA of HOX3A, but the gene is not expressed properly and a mutant phenotype results. In one mouse line, an mRNA is produced in normal amounts, but no HOX3A protein can be detected.

Suresh thinks the absence of protein results from a change in RNA processing that prevents the inclusion of an exon in the final mRNA. Gail thinks the absence of protein results from some second gene that produces a protein that binds to the 3'UTR. Which of the two could be correct?

A) Only Suresh could be correct.

B) Only Gail could be correct.

C) Both Suresh and Gail could be correct.

Answers

Answer 1

Answer:

C) Both Suresh and Gail could be correct.

Explanation:

The pre-messenger RNA (pre-mRNA) transcript obtained after transcription of eukaryotic genes must undergo several processing events, including a process known as intron splicing, where introns (i.e., the non-coding sections of an RNA transcript) are removed and exons (coding regions) are joined to form a mature mRNA molecule. The three prime untranslated (3′-UTR) region of this mRNA can also bind to regulatory non-coding RNAs such as, for example, miRNAs which inhibit gene expression by inhibiting translation and/or by triggering its degradation. Moreover, the 3′-UTR region may also contain silencer sequences that bind to repressors in order to inhibit gene expression. On the other hand, translation refers to the process by which an ordered polypeptide chain (i.e., a protein) is synthesized by using the information contained in an mRNA molecule. In consequence, in the case under consideration, the mutation in the second gene could affect both RNA processing and the regulation of translation, thereby equally affecting HOX3A protein synthesis.


Related Questions

When two long-winged flies were mated, the off spring included 77 with long wings and 24 with short wings. Is the short-winged condition dominant or recessive What are the genotypes of the parents

Answers

Answer:

the short-winged condition is recessive Both parents are heterozygous, Ll

Explanation:

Due to technical problems, you will find the complete explanation in the attached files.

An ecological footprint A) is a means of determining increases in populations that lived in the past. B) is a means of understanding resource availability and usage. C) measures dispersion and adaptability. D) will estimate population movements.

Answers

Answer: An ecological footprint is a means of understanding resource availability and usage. The correct option is B.

Explanation:

The ecological footprint is a method which is used to measure the rate as which humans use natural resources in their environment and generate waste from them compared with how fast nature can absorb these wastes and generate the used resources again. The productive areas which are measured through this means are:

--> cropland,

--> grazing land,

--> fishing grounds,

--> built-up land,

--> forest area, and carbon demand on land.

The importance of ecological footprint to the environment should no the over emphasizes. When properly observed, different environmental pollution would be dealt with. Generally, there would be:

--> decreased desertification,

--> decreased global warming

--> availability of fresh unpolluted air and

--> decreased carbon emissions.

What part of the body does cancer generally affect?

Answers

Answer: Cancer can spread anywhere through the body, but it's most likely to spread to lymph nodes, bones, the brain, the liver or the lungs.

Explanation:

Answer:

See below

Explanation:

Cancer can cause discomfort and loss of function in a specific section of the body by compressing surrounding nerves. Headaches and stroke-like symptoms and indications, such as weakness on one side of the body, are common symptoms and indicators of cancers that damage the brain.

Cancer may spread to any region of the body, although lymph nodes, bones, brain, liver, and lungs are the most commonly affected.

You fall backward and hit your head on a very sharp rock. The blow to your head causes you to lose consciousness and stop breathing. You most likely hit what part of your brain?

A) cerebellum
B) frontal lobe
C) brainstem

Answers

Choice C because the brain stem is the only one on the back of your head and it connects the brain to the rest of the body

how did world fromed​

Answers

Answer:

by allah talah

Explanation:

The Big Bang which was that we believe was a massive amount of gas and particles close together that caused a huge explosion causing the forming of stars. And some stars were big enough so when they died they made other elements such as rocks ice and water and gas

‼️‼️‼️‼️
Will give BRAINLIEST!! Please help!!

Answers

Answer:

A AND D I THINK PLZ MARK BRAINLIEST

The creation of genetically identical offspring by a single parent, without the participation of sperm and egg, is called The creation of genetically identical offspring by a single parent, without the participation of sperm and egg, is called spontaneous generation. asexual reproduction. regeneration. sexual reproduction.

Answers

Answer:

Asexual reproduction.

Explanation:

The generation of genetically identical offspring from a single parent, without the fusion of sperm and egg, is called asexual reproduction. Asexual reproduction occurs when there is only one parent from which organism is produced. Budding, binary fission and fragmentation are the different types of asexual reproduction that involves only one parent and no fusion of sperm and egg cells.

A lack of CO2 in the flask would have caused reduced O2 production. If O2 , ATP, and NADPH are the by-products of the light-dependent phase of photosynthesis, how does a lack of CO2 cause reduced O2 production

Answers

Answer:

Carbondioxide is a reactant of photosynthesis.

Explanation:

Carbondioxide is a reactant of the process of photosynthesis and the product of photosynthesis is oxygen, if there is no or less carbondioxide the rate of photosynthesis decreases which leads to the lower production of oxygen. The rate of photosynthesis affected by the reactants available to it. If Carbondioxide is available in large amount more photosynthesis occurs that leads to more production of glucose as well as oxygen. So we can conclude that lack of Carbondioxide results in lower production of oxygen in the process of photosynthesis.

A mutation that involves one or just a few nucleotides is known as what? A. point B. minor C. chromosomal​

Answers

That would be a point mutation

Answer:

Point

Explanation:


1. In some breeds of dogs, wire hair texture is dominant to smooth hair texture. Two parents with wire hair
produce an offspring with smooth hair. To express smooth hair, the offspring would need to have inherited
A. the same chromosomes from each parent.
B. an allele for smooth hair from each parent.
C. two of the same type of chromosomes from one of its parents.
D. an allele for wire hair from one parent and an allele for smooth hair from the other

Answers

B an allele for smith hair from each parent. They’d have to have two recessive alleles to show the trait

What is the first 20 element​

Answers

The First 20 Elements and The Difference Between Elements, Compounds and Mixtures. Standard. 1 – H – Hydrogen – Odorless, Colorless and Flammable Gas. 2 – He – Helium – Colorless and Odorless. 3 – Li – Lithium – Low Melting Point and Low Density. 4 – Be – Beryllium – High Thermal Conductivity and Non Magnetic.

Answer:

1. H - Hydrogen

2. He - Helium

3. Li - Lithium

4. Be - Beryllium

5. B - Boron

6. C - Carbon

7. N - Nitrogen

8. O - Oxygen

9. F - Fluorine

10. Ne - Neon

11. Na - Sodium

12. Mg - Magnesium

13. Al - Aluminum

14. Si - Silicon

15. P - Phosphorus

16. S - Sulfur

17. Cl - Chlorine

18. Ar - Argon

19. K - Potassium

20. Ca - Calcium

11. Stop codons are found in
and are responsible for?

Answers

Answer:

The presence of a stop codon—UAA, UAG or UGA—in the A site of the ribosome is generally a signal to terminate protein synthesis. This process constitutes the last essential stage of translation, as it ensures the formation of full-sized proteins

Can you help me with both questions

Answers

Answer:

b and c

Explanation:

Hope it helps:)

help me pls thank you

Answers

Explanation:

Interdependence. All organisms in an ecosystem depend upon each other. If the population of one organism rises or falls, then this can affect the rest of the ecosystem. If the foxes in the food chain above were killed, the population of rabbits would increase because they are no longer prey to the foxes.

What does DNA have to do with variation of a species?

Answers

Answer:

dna affects the physical appearence and also how our body works. changes in our dna can cause one to look different and have different functions from what a normal organism of that species has. as that organism with a mutation reproduces, its offspring will end up having similar features causing a variation in the species

Explanation:

cell like this has just left the lungs. What colour will it be?

Answers

Answer:

Within your blood, red blood cells have a specialized task. ... Your blood then transports carbon dioxide back to the lungs where you can ... They extend like tree branches into the lung.

Explanation:

HOPE IT HELP'S! C:

#CARRYONLEARNING

Describe an example of a plant responding to environmental stimuli

Answers

Answer:

Plants also detect and respond to the daily cycle of light and darkness. For example, some plants open their leaves during the day to collect sunlight and then close their leaves at night to prevent water loss. Environmental stimuli that indicate changing seasons trigger other responses.

Explanation:

Hope this helps you

Define el consepto de fraccion ​

Answers

Answer:

The concept of fraction

Explanation:

What is the concept of fraction tho? Fractions are numbers that represent a part of the whole. When an object or a group of objects is divided into equal parts, then each individual part is a fraction. ... It is divided into a numerator and denominator where the denominator represents the total number of equal parts into which the whole is divided.

A fraction represents the number of parts that we take from a unit that is divided into equal parts. It is represented by two numbers separated by a fraction line.

✧・゚: *✧・゚:* hello *:・゚✧*:・゚✧
Which of the following is not a strategy for reducing health risks from chemicals?
a.
eliminate the use of leaded gasoline
b.
reduce the sulfur content of fuel
c.
increase production of industrial chemicals
d.
limit worker exposure to chemicals

Answers

Answer:

c

Explanation:

If you wanted to reduce health risks, why make more?

Answer:

c

Explanation:

bc I said so

What’s the answer hurry it’s a test ?

Answers

Answer:

A: maintains genetic continuity from one generation to the next

Explanation:

I think A is correct because it mains genetic continuity from one generation of cells to the next. So all you cells in skin that are dead are replaced by the exact replica of next skin cells that arose from mitosis.

Gametes undergo meiosis and not mitosis.

Describe one property of water, and explain how the structure of water is responsible for this property. WILL MARK BRAINLIEST!!

Answers

Answer:

Water has cohesive and adhesive properties.

Water molecules have strong cohesive forces due to their ability to form hydrogen bonds with one another. Cohesive forces are responsible for surface tension, the tendency of a liquid's surface to resist rupture when placed under tension or stress.

How can extinctions and expansions occur in the same habitat? Explain your answer.

Answers

When a habitat is destroyed, the carrying capacity for indigenous plants, animals, and other organisms is reduced so that populations decline, sometimes up to the level of extinction. Habitat loss is perhaps the greatest threat to organisms and biodiversity.Extinction happens when environmental factors or evolutionary problems cause a species to die out. The disappearance of species from Earth is ongoing, and rates have varied over time.

Extinctions are associated with biodiversity changes, thereby affecting species expansion.

What is extinction?

Extinction refers to the disappearance of a given taxonomic group (e.g. species-level extinction).

This process of disappearance (extinction) modifies the trophic relationships in the ecosystem.

The modification may lead to the expansion of a given species (e.g., prey in the case of predator extinction).

In conclusion, extinctions are associated with biodiversity changes, thereby affecting species expansion.

Learn more in:

https://brainly.com/question/1048615

What are two examples of carbohydrates?
A. Fats and oils are carbohydrates.

B. Sugars and starches are carbohydrates.

Answers

Answer:

B. Sugars and Starches

Explanation:

Fats and oils are examples of fats

Answer:

Sugars and starches!

Explanation:

Sugars are a carb, and starches are a carb. Fats are the opposite, and oils are a type of fat as well.

Which of the following is true of Meiosis?
A. Meiosis does not require interphase to occur.
B. Meiosis requires DNA to copy itself twice
C. Meiosis produces haploid cells
D. Meiosis contains only one cell cell division
E. Meiosis occurs in all cells

Answers

Answer:

my true answer require is B

Do different patterns of electrical signals have unique
meanings?

Answers

Answer:

Plants use electric fields to communicate with bees, scientists have learned.

Bumblebees are able to find and decipher weak electric signals emitted by flowers, according to the study.

Tests revealed that bees can distinguish between different floral fields, as if they were petal colours. The electric signals may also let the insects know if another bee has recently visited a flower.

Explanation:

How bees detect the fields is unknown, but the researchers suspect the electrostatic force might make their hair bristle. A similar hair-raising effect is seen when placing one's head close to an old-style TV screen.

Flowers were already known to use bright colours, patterns and enticing scents to attract pollinators.

Mention at least three species of HPV(Human papinovirus)

Answers

Answer:

Shope papilloma virus, mastomys natalensis papillomavirus, and psittacus erithacus timneh papillomavirus

Can a hyena eat a coyote?

Answers

Answer:

Yes

Explanation:

Anything can eat anything. Sure the Coyote will pick a fight, and maybe something would turn the match right around, but yes, a hyena can eat a coyote.

Select all that apply.
Which statements about Archaea are true?
Archaea are able to live in high concentrations of salt water.
n Archaea are commonly found in your body, your food, and your home.
If you get food poisoning, you can most likely blame Archaea.
Archaea can be found at the bottom of the sea.

Answers

Yes you can be able to blame them most likely archaea is very poising


The shift in the stream was caused by movement at a __ boundary

A. converging
B. diverging
C. transform

Answers

A. Converging
Explanation
It’s A i’m just telling you that the answer is correct that the person above me said

When modeling fisheries: (You may choose one or more answers)
A. Fixed quota models result in multiple maximum sustainable yield population levels
B. Fixed effort models result in an inability to harvest at maximum sustainable yield
C. Fixed quota models are risky because slight miscalculations can result in fish population extinction
D .Fixed effort harvesting reduces the risk of population extinction

Answers

Answer:

Option A, Fixed quota models are risky because slight miscalculations can result in fish population extinction

Explanation:

Some of the major drawbacks of modelling fishing are as follows –  

a) The fixed quota model is very risky as a miniscule change in attributes can result into extinction of fish.  

b) On the other hand fixed effort harvesting can decrease the risk of fish population extinction

Hence, option A is correct

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