Suppose that you discover cells containing a mutation in a second protein and learn that this mutation also prevents mitotic cyclin from being degraded at the onset of mitosis, even when mitotic cyclin is normal. The degradation of other proteins appears to proceed normally in such cells. A mutation in what kind of protein might explain such results

Answers

Answer 1

Answer:

Mutations affecting proteins involved in the ubiquitination pathway

Explanation:

The cyclins represent a group of proteins capable of regulating the progression of the cell cycle via activation of cyclin-dependent kinases (CDKs). Cyclins are degraded by ubiquitination, a posttranslational modification that triggers the exit of mitosis by "marking" cyclin proteins for their subsequent degradation in the proteasome. The proteasome is a macromolecular complex required for the degradation of proteins in the cell. Then consequently the mutations affecting both secondary proteins required during ubiquitination and those involved in the functioning of the proteasome complex might prevent the degradation of cyclin proteins.


Related Questions

Researchers cross a corn plant that is pure-breeding for the dominant traits colored aleurone (C1), full kernel (Sh), and waxy endosperm (Wx) to a pure-breeding plant wiht the reccessive trains colorless aleurone (c1), shrunken kernal (sh), and starchy (wx). The resulting F1 plants were crossed to pure-breeding colorless, shrunken, starchy plants. Counting the kernals from about 30 eats of corn yields the following data:
Kernel Phenotype Number
Colored, shrunken, starchy 116
Colored, full, starchy 601
Colored, full, waxy 2538
Colored, shrunken, waxy 4
Colorless, shrunken, starchy 2708
Colorless, full, starchy 2
Colorless, full, waxy 113
Colorless, shrunken, waxy 626
6708
A) Why are these data consistent with genetic linkage among the three genes?
B) Perform a chi-square test to determine if these data show significant deviation from the expected phenotype distribution.
C) What is the order of these genes in corn?
D) calculate the recombination fraction between the gene pairs.
E) what is the interference value for this data set?

Answers

D) #recombinant=116+601+4+2+113+625=1462

   #nonrecombinant=2538+2708=5246

  RF=R/(N+R)=1462/6708=0.2

  E) I=1-Q

I-interference

Q-coefficient of coincidence

Q=O2Xo/E2xo(2xo-double crossovers)

O2xo=6

P=(distance from C1 to Sh/100)*(distance from Sh to Wx/100)

=(3.38/100)*(18.28/100)=0.006

E2xo=0.006*6708=40.248

Q=6/40.248=0.15

I=1-0.15=0.85

Drag the tiles to the correct boxes to complete the pairs. Match the organisms to the descriptions.

Answers

Answer:

Ok, no boxes but whatever

Mammals - Endothermic Homeostasis (Warm Blooded), Hairy Body, Have babies live

Birds - Endothermic Homeostasis(Warm Blooded), Have eggs, feathers, claws

Bacteria - Single celled, use binary fission to divide

Fungi - Multi or single celled, have chitin cellular walls

Plants - Have cellulose plant walls, multicellular organism

Archae Bacteria - Same as normal, except they live in crazy enviorments, like at the bottom of the ocean or in a volcano or radiation pool

Protozoa - Single celled organism class, like ameoba

Answer:

If this was edmentum. this was my question and answer

Explanation:

see pic below

Osteoporosis is characterized by Group of answer choices keratinization and death of epithelial cells. defective collagen production. immature red blood cells that lack hemoglobin. loss of bone mass and structure.

Answers

Answer: osteoporosis actually caused by lack of calcium

Explanation:

It is most common in womans....

And also immature red blood cells due to which blood calcium level decrease and cause osteoporosis

Vesicles:
-are transport compartments that can move particles into or out of a cell
-are surrounded by plasma membranes
-O are created by and are part of the endomembrane system or are created at the cellular membrane
-all of these
-O none of these

23

Answers

Answer:

all of these

Explanation:

Certain molecules like proteins and lipids are synthesized by organnelles in a cell. These molecules are transported by small membrane enclosed sacs in a cell called VESICLES.

Vesicles are small enclosures surrounded by a membrane made of lipid bilayer. This membrane separates them from the cytoplasm of the cell. They function as transport compartments that move particles in and out of the cell.

Vesicles are produced by some organnelles that make-up the Endomembrane system like Endoplasmic Reticulum, Golgi apparatus etc. while other vesicles are created as a result of endocytosis by the cell membrane. Vesicles can serve as secretory vesicles or transport vesicles etc.

where near your home do you think the highest level of photosynthesis is happening?​

Answers

Answer:

In the garden.

Explanation:

Because the garden contains photosynthetic plants.

Hope it helps.

Which statement below can NOT be used
when describing volume?
A. Volume is the amount of space that an object occupies.
B. The volume of an object is the same as the weight of that
object.
C. Volume can be measured in cubic centimeters.
D. Volume is calculated using a formula: V = 1xwxh.

Answers

Answer is B same as the weight of that

What should be done following health violations from an inspection?

Answers

Answer:

correct the identified

Explanation:

If health violations are found out during inspections, the inspector should give him warning about the violation or give him a ticket or fine. If high level of violation if found out, then the license of the restaurant or company should be cancelled.

What is heath violation?

Health violation is avoiding the condition that are necessary for health during the process or manufacturing. These violation leads to the poor health of the people.

Health inspectors are the person who check the conditions of hotel and factories related to the health of the people. If they found any violation, the companies should correct them.

Thus, the inspector should issue him a warning about the infringement or issue him a ticket or fee if any health violations are discovered during inspections. If a serious breach is discovered, the restaurant's or business' license should be revoked.

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Which best describes what happens to ATP during photosynthesis?

A. ATP is produced and then used to produce glucose.

B. ATP is broken down and then not used again.

C. ATP is formed and remains unchanged in the chloroplast.

D. ATP is changed to ADP and then moved to the cytoplasm

Answers

A. ATP is produced and then used to produce glucose.

ATP is produced in the light-dependent reactions and used in Calvin's cycle for glucose synthesis

Answer:

A) ATP is produced and then used to produce glucose.

Explanation:

Took the test edge2021

Chlorine is
used as
medicine why​

Answers

Answer:

Chlorine is used as a disinfectant in water treatment plants all over the world primarily because of its low cost and effectiveness. Basically, it gets rid of pathogens in the water and helps keep waterborne disease outbreaks at bay.

It is also used to treat many medical conditions and diseases, including high cholesterol, diabetes, cancer, stomach ulcers, anemia, depression, asthma, high blood pressure, inflammation and epilepsy

why standard units neeeded​

Answers

Answer:Because it is scientific and gives accurate results as well as accepted by the world.

Explanation:

Feel pleasure to help u...

Which of the following is the measure of the
chair's mass, or the amount of particles it has?
A. the length of a chair
B. the temperature of the chair
C. the color of the chair
D. the amount of matter in the chair

Answers

D. The amount of matter in the chair

Give 8 Differences each between immunization and immunity

Anyone that answers I will mark the person as brilliant

Answers

Answer:

1- The immune system develops antibodies to the disease so that it cannot make you sick again.

2- Immunization describes the actual changes your body goes through after receiving a vaccine.

3- Immunization is the process whereby a person is made immune or resistant to an infectious disease.

4- Vaccines stimulate the body’s own immune system to protect the person against subsequent disease.

5- Immunity is the capability of multicellular organisms to resist harmful microorganisms from entering their cells.

6- Immunity is the ability of an organism to resist a particular infection or toxin by the action of specific antibodies or sensitized white blood cells.

7- Immunization is the action of making a person or animal immune to infection.

8- Vaccines strengthen the immune system.

The term heterochromatin refers to heavily condensed regions of chromosomes that are largely devoid of genes. Since few genes exist there, these regions almost never decondense for transcription. At what point during the cell cycle would expect to observe decondensation of heterochromatic regions? Why?

Answers

Answer:

The correct answer is: S phase.

Explanation:

DNA can be divided into two functional forms: heterochromatin and euchromatin. Heterochromatin refers to the DNA that doesn't code for proteins or RNA, and thus it remains heavily condensed, for there would be no use to use it for transcription or translation. Euchromatin, on the other hand. is the DNA with the genes that can be transcripted into RNA and translated into proteins; for this reason, Euchromatin is less compact than Heterochromatin.

The only point in the cell cycle where Heterochromatin would be decondensed is S phase because, in this part of the cell cycle, the DNA gets replicated in order to prepare for Mitosis. For DNA to be replicated, it first needs to be decondensed to their two strands can be separated and used as guides for the synthesis of the two new strands.

Write down the oxygen requirements of the microorganisms growing in thioglycolate tube.

Answers

Answer:

Obligate aerobic microbes requires oxygen for its survival in the thioglycolate tube while Obligate anaerobic microbes does not requires oxygen.

Explanation:

Thioglycolate tube is a tube which is used to determine the oxygen requirement of different types of microbes. The concentration of oxygen is higher in the upper portion of the tube while in the lower portion, the concentration of oxygen is the lowest. So those microbes who needs oxygen for their survival will be present in the upper portion of the tube while those microbes who does not need oxygen, will be present at the bottom of the tube.

write the name of 5 plants that reproduce by stem?

Answers

Answer:They are

Ginger

Potato

Basil

Rosemary

Lavender

Explanation:Feel pleasure to help u...

Answer:

Onions , ginger, gladiolus, common ivy, dahlia

Explanation:

Did this help?

What structure is found mostly in green plant cells but not in animals

Answers

Answer:

The answer is Chloroplast.

Explanation:

Chloroplast is a structure in green plant cells which contain a substance called chlorophyll which give plant leaves their green color.

Hope this helps you

The immune system responds to the damage to arteries because of atherosclerosis by: a. destroying foam cells that capture and remove LDL from the artery wall b. promoting the growth of skeletal muscle cells of the artery wall to repair the site c. sending white blood cells to the site to try repair the damage d. reducing the concentration of clotting factors in the blood e. lining the arteries with high levels of HDL cholesterol

Answers

Answer:

The correct answer is option C.sending white blood cells to the site to try to repair the damaged

Explanation:

Atherosclerosis is a disease where plaque develops inside arteries. Arteries are vessels that convey oxygen-rich blood to your heart and different regions of your body. Plaque is comprised of fat, cholesterol, calcium, and different substances found in the blood. After some time, plaque solidifies and limits your supply routes.

The immune system responds to Atherosclerosis that causes damage to the arteries by sending white blood cells to the damaged site to fix the damage caused by the plaques and fat deposits that obstruct the blood supply.

The immune system responds to the damage to arteries because of atherosclerosis by C. sending white blood cells to the site to try repair the damage.

The immune system is the process that is important for resistance against diseases and fighting infection. It defends our body against invaders such as bacteria, viruses, etc.

It should be noted that the immune system responds to the damage to arteries because of atherosclerosis by sending white blood cells to the site so that the damage will be repaired.

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In the case of two EPSPs occurring at a single synapse, which of the following will produce a subthreshold effect and not generate an action potential on the postsynaptic neuron’s axon hillock?

a. Both EPSPs occurring in rapid succession
b. The summed EPSPs depolarizing the axon hillock membrane to —70 mV
c. Both EPSPs occurring before the postsynaptic membrane potential returns to —55 mV
d. Both potentials occurring after the postsynaptic membrane potential returns to its resting value

Answers

Answer:

Both potentials occurring after the postsynaptic membrane potential returns to its resting value

Explanation:

This is simply because, a neuron returning to its resting state,will have the ligand gated Na+ channels closed.Therefore depolarization can not occur.More K+ gated channels will open, and more K+ leaks out of the axoplasm,returning the neuron to the resting state.

Hence if  the summation of the two EPSP returns to the resting level after crossing the synapse, they can not propagate,and generate action potential, because they will produce  a sub threshold effects,which  will not generate action potential.

a smoker develops damage to several alveoli that can no longer function. how does this affect gas exchange?

Answers

Answer:

Smoking causes the hardening of the alveoli walls. This keeps them from extending or stretching out because of the loss of elasticity. In such a circumstance, it is hard to take up oxygen from the inspired air or to remove carbon dioxide from the circulation system. This would prompt partial or less trapping of the gases in the lungs.  

With this damage due to smoking, the alveoli can not assist the bronchial tubes enough. The tubes also get damaged and cause a blockage or obstruction, which traps air inside the lungs. An excess of air caught in the lungs can give a few patients a barrel-chested appearance.

Rabies vaccines in dogs: a. Are always given yearly b. Can treat the disease c. Are legally required in the United States d. Are voluntary in all states

Answers

Answer:

The core vaccines include the DHLPP (distemper, hepatitis, leptospirosis, parvo, and parainfluenza).

Explanation:

Your pup will also need a rabies vaccination, which is usually around $15—20. (Some clinics include the cost of the rabies vaccination.) hope this helps you :)

Answer:

Are given yearly.

Explanation:

Looked it up :)

Schilders disease is a progressive degeneration of the central nervous system that leads to death by age 2. The disease is caused by a simple autosomal recessive mutation. A couple loses its first two children to Schilders disease. If they decide to have a third child, what is the probability that it will have the disease

Answers

Answer:

The probability will be 25% (1/4)

Explanation:

Schilder's syndrome is a degenerative and progressive lethal disease caused by the demyelination of nerve cells in the brain and spinal cord. Since it is a lethal recessive autosomal disease, both the father and the mother have a single copy of the mutant allele, thereby the probability of obtaining a lethal combination will be:

SN X SN >>

1/2 x 1/2 = 1/4 = 25%

where N and S are normal and lethal alleles, respectivelyvely

1 2.1.5 Quiz: Specialized Cells and Tissues
Question 5 of 5
2 Points
Which statement best explains how the needs of a unicellular organism are
met?
A. Only its specialized cells work together.
B. All of its cells must work together.
C. Most of its tissues work together.
D. Its cell parts must do everything.
SUBMIT

Answers

Answer:

B. All of its cells must work together

Its cell parts must do everything explains the needs of a unicellular organism are met. So, the correct option is D.

What are Unicellular Organisms?

A unicellular organism is also called as a single-celled organism, which is defined as an organism with a single cell, in contrast to a multicellular organism, which consists of many cells. Organisms fall into two categories: prokaryotic organisms and eukaryotic organisms.

Amoeba and Paramecium both are protozoans which belongs to Kingdom Protists that are unicellular organisms. Unicellular organisms are organisms that have only one cell that performs all vital functions including metabolism, excretion, and reproduction. Its cell parts must do everything explains the needs of a unicellular organism are met

Therefore, the correct option is D.

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Estrogens from the vesicular follicle trigger an LH surge from the anterior pituitary. This is an example of: Estrogens from the vesicular follicle trigger an LH surge from the anterior pituitary. This is an example of: negative feedback first tier of control positive feedback fourth tier of control

Answers

Answer:

The correct answer is: positive feedback.

Explanation:

Positive and negative feedback are terms that are used to define the way a system is regulated by its products. For example, when the production of a certain substance inhibits its producer that is called negative feedback. On the other hand, when a substance stimulates its producer to keep secreting said substance, this is called positive feedback.

Estrogen is a hormone of great importance in the female reproductive cycle and is secreted by the follicle cells in response to the presence of FSH (follicle-stimulating hormone), released by the anterior pituitary when stimulated by the GnRH (gonadotropin-releasing hormone).

Estrogen appears at the beginning of the cycle to stimulate the development of the ovarian follicles, and the hormone levels continue to rise as the cycle advances. Up until the 14th day of the cycle, estrogen has a negative feedback on GnRH and FSH, but then it makes an abrupt change to now exert positive feedback on GnRH to stimulate the release of LH (luteinizing hormone), which will be responsible for ovulation.

Discuss with erica what appropriate internet usage on the job look like

Answers

Explanation:

Download or upload obscene, offensive or illegal material.

Send confidential information to unauthorized recipients.

Invade another person’s privacy and sensitive information.

Download or upload movies, music and other copyrighted material and software.

Visit potentially dangerous websites that can compromise the safety of our network and computers.

Perform unauthorized or illegal actions, like hacking, fraud,

Which component of a virus is injected into an infected cell? ribosome nucleic acid protein capsid mitochondrion

Answers

Answer: The component of virus is injected into an infected cell is RNA or DNA, aur nuclei acid.

Explanation:

Nucleic acid is injected into an infected cell.

What component is injected into the infected cell?

During attachment and penetration, the virus attaches itself to a host cell and injects its genetic material into it. During uncoating, replication, and assembly, the viral DNA or RNA incorporates itself into the host cell's genetic material and induces it to replicate the viral genome.

What does the nucleic acid do in a virus?

Nucleic Acid - Just as in cells, the nucleic acid of each virus encodes the genetic information for the synthesis of all proteins. While the double-stranded DNA is responsible for this in prokaryotic and eukaryotic cells, only a few groups of viruses use DNA.

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Who first identified nucleic acids, and where were they discovered?
A Friedrich Meischer discovered nucleic acids in blood cells.
B Phoebus Levine discovered nucleic acids in plant cells.
C James Watson and Francis Crick discovered nucleic acids in DNA.
D Gerardus Johannes Mulder discovered nucleic acids in bacterial cells.

Answers

Answer:

A

Explanation:

He discovered them in 1868. I hope this helps:)

Friedrich Meischer, a Swiss physician and biologist, is credited with the discovery of nucleic acids. The correct option is A.

What is Nucleic acid?

Nucleic acids are complex macromolecules that play a fundamental role in storing, transmitting, and expressing genetic information in living organisms. They are essential for the inheritance of traits and the functioning of cells. There are two main types of nucleic acids: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).

In the late 1860s, Meischer was conducting experiments on white blood cells (leukocytes) and noticed that these cells contained a substance that was different from proteins.

He isolated this substance, which he called "nuclein," from the nuclei of white blood cells.

Meischer's discovery laid the foundation for our understanding of nucleic acids.

Thus, the correct option is A.

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Define and compare four level of protein organization.

Answers

Explanation:

There are four levels of protein structure: primary, secondary, tertiary, and quaternary. These levels also reflect their temporal sequence. Proteins are synthesized as a primary sequence and then fold into secondary → tertiary → and quaternary structures.

According to research, what role do genes play in determining whether someone will develop an anxiety disorder

Answers

Answer: Here are the options.

A. Unknown

B. No role.

C. Fully determines.

D. Can contribute but does not fully determine.

The correct option is D.

Can contribute but does not fully determine.

Explanation:

According to research, Genes can contribute to anxiety disorder but cannot fully determine because certain chromosomal or genes are linked to panic or anxiety disorder. Scientist discovered that RBFOX1 gene may make someone more likely to develop generalized anxiety disorder which shows that anxiety disorder are linked to genes. Anxiety disorder can be inherited and it is linked to specific genes.

Anxiety disorder is a feeling and not a mental illness. They symptoms of anxiety disorder are phobias, excessive worrying, memory problems, tensed muscles, irritability, struggle to sleep e.t.c. Some environmental factors also can contributed to anxiety disorder.

as an aspiring nurse,the need for the culture of a new pathogenic microorganism in the laboratory has been allocated to you. Applying all the guidelines involved in the successful isolation and cultivation of microbes, discuss the culturing system that is most appropriate for this activity and state your reasons for this choice​

Answers

Answer:

The culturing system depends on the sort of microbe allotted to segregate namingly bacteria, viruses, or fungi. Each microbial pathogen has particular culture media for disconnection and for development or replication, we need culture media.for model bacterial pathogen can be separated by plating the example in fitting media by 3 strategies that are streak plate or pour plate or spread plate  

Out of the above streak, plate gives the best outcomes in single disengaged provinces which can be additionally cultured and characterized for creation of pure culture

The cyclin B–Cdc2 complex controls the passage from G2 into M and is assembled before mitosis however, its catalytic activity is restricted to mitosis. What process is responsible for the activation of the cyclin B–Cdc2 complex?

Answers

Answer:

Phosphorylases that selectively add phosphate groups to the Cdc-2 subunit, thereby activating this complex.

Explanation:

The cyclin B-Cdc-2 (also known as maturation-promoting factor or simply MPF) complex is activated when it enters into the nucleus during the G2/M transition in the cell cycle. Cdc-2 is a protein kinase that associates with cyclin proteins. These proteins (cyclins) regulate the cell cycle by activating cyclin-dependent kinases. It is well known that phosphorylation of the Cdc2 subunit at different residues can both activate and inactivate the MPF complex. Moreover, enzymes capable of both inactivating phosphorylases and activating phosphatases have also shown to be able to activate MPF.

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