Nuclear hormone receptors form a complex with their ligands, other proteins, and DNA control elements in order to regulate the expression of specific genes. These nuclear hormone receptors have four principal domains. Categorize each trait according to the appropriate nuclear hormone receptor domain with which it is associated.

Answers

Answer 1

Answer:

Explanation:

Nuclear receptors are a type of protein that functions as an intracellular steroid and thyroid hormone receptor. The interaction of these hormones in conjunction with nuclear receptors changes the pattern of gene expression, allowing certain genes to be transcribed while others are silenced.

As a consequence, unique mRNA translation products, proteins, and, in most cases, enzymes are generated. Nuclear receptors connect to DNA directly and control the expression of certain genes, regulating the organisms growth, homeostasis, and metabolism.

The following domains are found in a normal nuclear receptor:

The amino-terminal activation domain contains the transcriptional activation mechanism and is strongly variable in sequence (AF1). The recruiting of coregulators is the domains key feature.

⇒ Activation function 1 (AF1); Coregulator recruitment

DNA binding domain: It is amongst the most closely conserved centrally located domains, with two zinc fingers that attach to specific DNA sequences known as hormone reaction components (HRE).

⇒ nine conserved cysteine residues; zinc finger domain; center of the receptor.

The hiinge domain serves as a versatile connection between the DNA binding and ligand-binding domains. It has a nuclear localization signal in it. ⇒ Nuclear localization signal

Ligand binding domain:  The sequence of the ligand-binding domain is moderately conserved throughout nuclear receptors. It denotes the carboxyl-terminal end of a ligand domain. It has hydrophobic steroid-binding pockets that draw the hormone and AF2 activation domains. It also attaches to proteins that serve as coactivators and corepressors.

⇒ binding of corepressor proteins;  steroid-binding hydrophobic pocket; AF2 activation domain; binds coactivators; carboxyl-terminal end


Related Questions

In a eukaryotic cell in mitotic S-phase, a spontaneous DNA double-strand break occurred due to replication fork collapse. Genetic analysis indicates that the break was repaired by a non-crossover mechanism resulting in a stable genome. The DNA repair process responsible for this outcome was:

Answers

Answer: The DNA repair process was called recombination repair.

Explanation: A sister or homologous chromatide is used to generate recombination and be repaired in this sort of cases.

The Earth's core has an estimated temperature between

Answers

Answer:

5,700 to 6700

Explanation:

The temperature at the inner core's surface is estimated to be approximately 5,700 K (5,430 °C; 9,800 °F), which is about the temperature at the surface of the Sun.

How is a lake succession different from the succession of an open field?

Answers

Answer:

Lake Succession (Research suggests a different model: a lake may undergo hundreds of years with little succession, with brief episodes of rapid change.) 1.An open lake or pond experiences a drought of one or more decades and the water level falls.

Explanation:

What is one type of light that can be used for photosynthesis

Answers

Answer:

The majority of green light is useful in photosynthesis. The relative quantum efficiency curve (Photo 1) shows how efficiently plants use wavelengths between 300 and 800 nm. Green light is the least efficiently used color of light in the visible spectrum.

what are the two ways mitosis and meiosis increases genetic diversity?​

Answers

Answer:

crossing over, and mutations caused during crossing over.

Explanation:

Because of recombination and independent assortment in meiosis, each gamete contains a different set of DNA. This produces a unique combination of genes in the resulting zygote. Recombination or crossing over occurs during prophase I.

Maintaining high global biodiversity is important to provide ecosystem services to humans. Describe one cultural ecosystem service provided by diverse ecosystems.

Answers

Answer:

Ecosystem services of provision or supply

Explanation:

Ecosystem services

When talking about ecosystem services, we are referring to the benefits that ecosystems provide us. There are four types of ecosystem services:  

Provision or supply:

These are the products obtained by nature to be used or consumed, directly or with previous processing. Among them, we might mention food, clear freshwater, fertile soils, geotic materials (such as salt), raw materials (that can be used for clothing, construction), renewable fuels, biochemical compounds, pharmacological/medicinal resources, among others. Provisioning service has an impact on the economy, as many of these products are used to commercialize.  

Regulation:

Refers to ecological processes that improve life. Among others, we might mention climate regulation, CO² absorption, water purification, air purification, erosion control, natural disaster avoidance such as flooding, soil fertility maintenance, waste recycling, pests/plagues control, etc.  

Cultural:

Refers to not the material benefits. Ecosystems also provide a recreational place or area to spend time, to learn, provide a spiritual/religious space, are a source of inspiration. Ecosystems are considered to be cultural patrimony. Ecosystems are the source of scientific knowledge.

Support:

Involves ecological processes needed for the production of the other three previously mentioned services. There are five different support services:

→ Soil formation

→ Photosynthesis

→ Primary production

→ Nutrients cycles

→ Water cycle

Under certain circumstances, regulation services can also be considered support services.

Support service affects human beings indirectly, or direct but causing an effect in a long-term period.  

PLEASE HELP ASAP!!!!
Which of earth's biomes has the least biodiversity?
grassland
coniferous forest
tundra
rainforest

Answers

Answer:

It's the tundra

Explanation: I say that because the tundra, which literally means "treeless plain," is the coldest biome. Extremely low temperatures, limited precipitation, a short growth season, minimal biodiversity, and nutrients in the form of decaying organic matter are all characteristics of tundra.

There are 434 trees in a 12 square meter area. What is the population density?

Answers

Answer:

36 1/6

Explanation:

434÷12=36 1/6

population density is number of trees in one square meter

this is an easy science question please help




Assume that a flood washed out all of the plants in a large area along the bank of a river. It left behind
nothing but soil. How will ecological succession occur in this area?

Answers

Answer:

ecological succession in this area will washout and more danger to many citizens on that area.

The atmosphere has become less polluted over time.
Please select the best answer from the choices provided

True or false

Answers

Answer:

False your answer is = False

False is the answer

How does carbon end up accumulating in soil carbon pools?​

Answers

Answer:

Soils play a key role in the carbon cycle by soaking up carbon from dead plant matter. Plants absorb CO2 from the atmosphere through photosynthesis, and pass carbon to the ground when dead roots and leaves decompose. This net release of carbon to the atmosphere contributes to global warming.

Explanation:

(If this didn't help, I'm sorry but i tried my best )

List and briefly describe the chemical sequence of events in the fight-or-flight response to a threatening situation from the binding of epinephrine at the receptor site to readiness for another situation.

Answers

Answer:

Binding taking place at the receptor site

G protein activates in the cell membrane

Conversion of GDP → GTP

Activation of adenylate cycles

Cyclic production of AMP → ADP

Initiation of the desired reaction in regard to the original message

Cyclic restoration of AMP → ATP

Explanation:

The description of the mechanism:

Right off the bat, epinephrine attaches to a molecule called a receptor (beta-adrenergic protein).

G protein, which is found on the inner side of the plasma membrane, is activated when epinephrine binds to it.

The GDP-carrying Alpha subunit of G protein is isolated during activation. After that, the GDP is translated to GTP.

Adenylate cyclase is then activated by GTP.

The only enzyme that can catalyze the transformation of ATP to CAMP is adenylate cyclase (Cyclic adenosine monophosphate). As a result, the CAMP molecule (secondary messenger) is produced.

CAMP stimulates protein kinase A, and the cycle repeats till the glycogen phosphorylase enzyme is triggered.

After that, the cyclic amp is brought back and restored.

what is evolution?...​

Answers

Answer:

Evolution is an adjustment of the heritable attributes of natural populaces over progressive ages. These attributes are the outflows of qualities that are given from parent to posterity during generation. There are also three main types of evolution: divergent, convergent, and parallel evolution.

Explanation:

A biologist grows bacterial cultures to see if there is a relationship between time and growth rate. Here are the data. Which hypothesis test would you use to see if there a relationship between growth rates and time

Answers

Answer:

Direct relationship.

Explanation:

There is direct relationship between growth rates and time which means growth rate of organism increases with the passage of time. Direct relationship means if one increases the other automatically increases and if one decreases, the other also decreases. The growth of bacteria becomes double when more time passes and vice versa. After every 20 minutes, the population of bacteria becomes double.

g Cells called ________ influence development by controlling the fate of other cells in their local environment

Answers

Answer:

Neighboring Cells

Explanation:

Neighboring Cells are known to be the type of cells that influence development by controlling the fate of other cells in their local environment.

Typically Neighboring cells through the process often referred to as Induction simply influence the development of other cells nearby or in their local environment. This process of cell influence is either by direct cell-cell contact or through the release of practice chemical signals.

Hence, in this case, the correct answer is "Neighboring Cells."

formula to calculate marginal rate of substitution ​

Answers

Answer:

(MRSxy) = ∆Y/ ∆X

Explanation:

7. Scrie metoda corectă de separare a substanțelor corespunzătoare următoarelor
amestecuri:
Amestecuri
Metode de separare a amestecurilor
Boabe de fasole și apă
Plante medicinale în ceai
Resturi menajere din chiuvetă TE ROG REPEDE DAU COROANA LA PRIMUL CARE RASPUNDE‼️‼️‼️​

Answers

Answer:

por favor, ingles para bio

Explanation:

Atleats put the answer not just d

Answers

Uhh I think you meant to comment not ask a question

Answer:

what do u mean owo

Explanation:

Suppose we have one true-breeding strain of tomato that produces red fruit. Suppose we also have a true-breeding strain of tomato that produces yellow fruit. We KNOW that a single gene is responsible for fruit color, and that the red allele is dominant to the yellow allele. If you make an F2 cross, what proportion of those fruits would you expect to be yellow

Answers

Answer:

1/4 or 25%

Explanation:

Let us assume that the fruit color trait in the tomato is represented by R and r. The dominant color red would be represented by R while the recessive color yellow would r.

If a true-breeding red fruit tomato (RR) is crossed with a true-breeding yellow fruit tomato (rr), the F1 would be thus:

             RR    x    rr

          Rr   Rr   Rr   Rr

Since R is dominant over r, all the F1 offspring would produce red fruits with the genotype Rr.

At F2:

               Rr    x    Rr

           RR   Rr   Rr   rr

RR and Rr = red

rr = yellow

Hence, the proportion of the F2 offspring expected to be yellow would be 1/4 or 25%.

how to write a bibliography

Answers

Answer:

Include above things and write your own biography

Author/editor(s)Publication date(s)Title.Publisher/company.Volume.Pages.Websites.

In the pine bush/pine barrens of the northeastern United States, fire suppression has seen native, fire-dependent pitch pine trees (Pinus rigida) replaced by black locust (Robinia pseudoacacia). This would be an example of the role that Group of answer choices

Answers

Answer:

disturbance plays in competition.

Explanation:

Fire-dependent pitch pine trees (Pinus rigida) is replaced by black locust (Robinia pseudoacacia) because of disturbance that occurs in the environment naturally. When disturbances occur naturally, they provide conditions that favor the success of different species over the native organisms. The native organisms are vanished from that ecosystem due to changing of environmental conditions and other organisms settle there which can survive in that environment.

9 raise to the power of 1-x equal to 27 raise to the power of y equal to -1whole number 1/2​

Answers

Answer:

Given series is 9

1/3

×9

1/9

×9

1/27

×.....∞

=9

(

3

1

+

9

1

+

27

1

+....∞)

=9

(1−r)

a

, where a=

3

1

and r=

3

1

=9

(1−

3

1

)

(1/3)

=9

2

1

=

9

=3.

Suppose a new species of shark is discovered, and the dorsal fin length is found to be determined by additive alleles at three independently assorting loci (A, B, and C). The dorsal fin length of aabbcc sharks is 12 cm, and the dorsal fin length of AABBCC sharks is 30 cm. Assuming that the alleles contribute equally, what will be the length (in cm) of the dorsal fin of an animal with genotype AAbbcc

Answers

Answer:

The length of the dorsal fin of an animal with genotype AAbbcc is 18 cm

Explanation:

Due to technical problems, you will find the complete explanation in the attached files.

Deer are eating Mr. Thompson's rose bushes. He puts a new deer repellent point on half of his rose bushes and then waters them. He uses the same amount of water on the other half of his rose bushes but does not put the repellent on them. What is the control group for his experiment?
A: the rose bushes with deer repellent
B: the rose bushes without the deer repellent
C: the amount of water used
D: the type of brush used

Answers

Answer:

B. The rose bushes without the deer repellent

Explanation:

In an experiment, the control group is often the group that is not exposed to the independent variable.

The control group is usually used for comparison between it and the experimental groups.

In this experiment, the rose bushes without the deer repellent are the control group.

As the control group, these rose bushes will be compared to the ones that have deer repellent.

The correct answer is B. The rose bushes without the deer repellent

How does the tuna get energy from the Sun?

Answers

Answer:

Phytoplankton are the foundation of ocean life, providing the energy that supports nearly all marine species.

hope this helps

have a good day :)

Explanation:

You have formulated a hypothesis. Pineapples contain more vitamin C. than oranges. to test this hypothesis you measure vitamin C levels in 20 oranges and 20 Pineapples from trees that were grown in the same orchard under the environmental conditions, ( temperatures, rain, sunlight) select all the statements that are true about this experiment

a. The independent variable is temperature
b. the control group in the experiment is the oranges
c. The type of fruit is a controlled variable
d. The dependent variable is the vitamin C levels in the pineapples and oranges

Answers

Answer:

d. The dependent variable is the vitamin C levels in the pineapples and oranges.

Explanation:

Select all the statements that are true about this experiment.

a. The independent variable is temperature. NO, temperature, as well as rain and sunlight are controlled variables and are not being evaluated in the experiment.

b. the control group in the experiment is the oranges. NO, there is no control group in this particular experiment.

c. The type of fruit is a controlled variable. NO, the type of fruit is the independent variable.

d. The dependent variable is the vitamin C levels in the pineapples and oranges. YES. According to your hypothesis, the vitamin C levels depend on the type of fruit.

what the persentage chance that the offspring will be dwart plant yellow fruit

Answers

Answer:

Yellow fruit and dwarf vines are recessive traits in tomatoes. Red fruit and tall vines are dominant. Complete a Punnett square and answer the questions for a completely dominant red and tall plant crossed with a heterozygous red and dwarf plant.

A passenger in a car is holding an open water bottle when the car stops suddenly. Why does the water in the bottle splash out when the car stops?

Answers

the force of bestop will fling you forward and the water will go to one side of the bottle and hit the side of the bottle and curved back up and come out because the force of

Answer:

C. It has inertia

Explanation:

just did it and got it right on edg 2021

I NEED HELP ASAP
Describe a cause of aerosol (particulate matter) pollution; then briefly explain its effect on human health.

Answers

A major cause of aerosol pollution is the burning of fossil fuels, such as coal, oil, and natural gas for transportation, energy production, and industrial processes.

What is aerosol pollution?

Aerosol pollution is also known as particulate matter pollution. It refers to the presence of tiny solid and liquid particles which are known as particulate matter, in the air. These particles can come from a variety of sources, including vehicle exhaust, industrial processes, construction activities, wildfires, and dust storms.

Aerosol pollution can various harmful effects on human health, as the tiny particles can easily penetrate deep into the lungs and bloodstream when inhaled. Exposure to high levels of aerosol pollution has been linked to a range of health problems, including respiratory and cardiovascular diseases, cancer, and premature death.

Learn more about aerosol pollution, here:

https://brainly.com/question/14313232

#SPJ2

If a heterozygous type A (ABO blood type) male crossed with a type O female, what would be the phenotypic ratio of type A: type B: type AB: and type O in the offspring?

Answers

Answer:

2/4 A and 2/4 O

Explanation:

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