Just a quick summary will do!:

A. Sickle Cell Anemia is caused by a base change in DNA. Describe how the base change results in a faulty protein being made.

B. Briefly explain the inheritance pattern of the condition.

Answers

Answer 1

Answer: a) The single base change mutation occurs at the beta chain of haemoglobin when glutamic acid is replaced with valine.

b) Sickle Cell Anemia is inherited in an autosomal recessive pattern.

Explanation:

Haemoglobin is a protein found in the red blood cells whose main function is to transport oxygen. Sickle Cell Anemia is a disorder caused by a base change in DNA beta chain of haemoglobin. The amino acid valine is substituted for glutamic acid at one point in each of the two beta chains. When this type of hemoglobin is exposed to low oxygen, it forms elongated crystals inside the red blood cells that are sometimes 15 micrometers in length. These make it almost impossible for the cell to pass through many small capillaries, and the spiked ends of the crystals are likely to rupture the cell membrane, leading to sickle cell anemia.

In describing the inheritance patterns of sickle cell anaemia, it is of autosomal recessive pattern. This means that the parent of the affected individual both carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. The gene for normal red blood cell is dominant over the gene for abnormal red blood cell which is said to be recessive. A person who is a stickler should have the genotype SS.


Related Questions

transcribe the DNA strand below into RNA​

Answers

Answer:

CGTACG

Hope it helps ❤️....

How was osmosis used to stop Clark’s seizures?

Answers

Answer:

after Clark was treated with a hypertonic solution? increased Na concentration in matrix of brain caused water from blood to move in to the brain which increased the matrix pressure. Pressure caused the neuron firing rate to increase which increased the likelihood of seizures.

Explanation:

hope this helps   :)

The osmosis used to stop Clark’s seizures should be considered as the hypertonic solution.

Usage for stopping the Clark’s seizures:

After clark it was treated with the hypertonic solution.

Here Na concentration should be increased in matrix of brain that leads to water from blood for moving in brain that increased the matrix pressure.

hence, The osmosis used to stop Clark’s seizures should be considered as the hypertonic solution.

Learn more about osmosis here: https://brainly.com/question/20015875

It is always important to note possible sources of error in the conclusion.

A. True
B. False

Answers

A. True. y'w c: C; now have good day

The answer is True

Someone please correct me if I am wrong.

Please help Why must animals eat food but plants do not eat food?(1 point) Plants do not appear to eat, but they do actually eat nutrients in the soil. Animals must eat to obtain food that they can't get from the soil. Plants make their own food through photosynthesis, so they do not eat. Animals eat because the energy they make themselves is enough to live but not grow. By eating, they can grow big and strong. Plants use photosynthesis to make their own food instead of eating. Animals eat plants because they like the taste of certain fruits. Plants make their own food through photosynthesis. Animals must eat because they cannot make their own food.

Answers

Answer:

Because they will die if they don't eat food, they need the protein to keep them moving and there muscles strong. Some animals get food off of other animals.

Explanation:

Answer:

Explanation:

Well there is animals who only Eat plants and not other animals

Examples of large herbivores include cows, elk, and buffalo. These animals eat grass,

tree bark, aquatic vegetation, and shrubby growth. Herbivores can also be medium-sized

Hope this helps

A picture of a Constructed food prymid

Answers

Answer:

https://en.wikipedia.org/wiki/Food_pyramid_(nutrition)

Explanation:

what species of organism does the gene donor cell belong to?

Answers

Answer:

Prokaryotes, which include bacteria and single-celled microorganisms called Archaea, usually pass their chromosomal DNA on to their offspring asexually. In other words, a bacterial cell reproduces by simply replicating its chromosome and dividing into two daughter cells. The daughter cells that result from this division are genetically identical to each other and to the original parent cell. Thus, over time, asexual reproduction in bacteria can lead to a population of hundreds of thousands of cells, all of which are genetically identical to a lone original parent cell.

Given their asexual method of reproduction, it is tempting to think that bacteria are sorely lacking in genetic variation, but this is not the case. Prokaryotic cells have developed a number of methods for recombining their genetic material, which, in turn, contributes to their genetic diversity. The three most common ways that bacteria diversify their DNA are transformation, conjugation, and transduction. However, not all types of bacterial cells are capable of engaging in all three processes.

Which of these functions in energy production, known as the energy factory of the cell *
6 points
chloroplast
mitochondria
vacuole
cytoplasm

Answers

It is the mitochondria

PLS ANSWER IM SO CONFUSED.................Organisms other than humans are_____ to certain climates and would not survive in other climates.

Answers

i think it’s humans are not aloe of

Which of the following is a disadvantage to using chlorine for disinfection of water?

Answers

Answer:

Damage our health.

Explanation:

The levels of chlorine used for disinfection of drinking water causes long-term health effects because chlorine is toxic substance that greatly damaged cells and tissues of our body. Chlorine has low protection against protozoa due to its ineffectiveness on the protozoans organisms. These protozoa also adversely affected our health so we can say that chlorine has to be used in a limit which does not harm our body.

Answer:

Chlorine reacts with organic compounds.

Explanation:

Chlorine reacts with organic matter to create chlorination byproducts which often change the overall chemical properties of water.

itroduction for fats and oil​

Answers

Thanks to the person above me !!

How do ocean currents affect temperature? Check all that apply.

Answers

Answer:

They carry cold water from the poles to the equator and cool air over land. They move warm water from the equator to the poles and heat air over land.

Explanation:

So That Is Why

Answer:

A & D

Explanation:

A piece of virus DNA that becomes a part of a bacterium's genome is called a

a) prophage

b) bacteriophage

c) endospore

d) retrovirus

Answers

Answer:

a) prophage

Explanation: triggered to become active with exposure to radiation, heat, a particular chemical, or some other factor

What are two functions of large intestine?

Answers

Answer: The purpose of the large intestine is toabsorb water and salts from the material that has not been digested as food, and get rid of any waste products left over. By the time food mixed with digestive juices reaches your large intestine, most digestion and absorption has already taken place.

What do you think could make the magnetic force produced by the launcher system so much stronger in the Wednesday launch than in the Tuesday launch, even though the spacecraft was moved the same distance closer?

If I were you only answer this if you do amplify

Answers

Answer:Magnetic forces are stronger closer to magnets. The Wednesday test launch stored more potential energy, and launched the spacecraft at a faster speed because the stronger magnetic field closer to the magnet resulted in a greater increase in potential energy.

Explanation:

Which is the most recent if selectively bred carrot flavor profiles

Answers

Answer:

Sweet and juicy.

Explanation:

This is because sweet and juicy flavor happens to be a good and tasty flavor that everyone would love and it was developed to achieve these phenotypic trait by selectively breeding two different carrots species to achieve these desired traits. It was gotten after researches has been done to satisfy human desires of consuming something sweet and juicy.

Kevin is a crime scene investigator. He believes he has found saliva on the floor of a crime scene. Since he cannot cut out a piece of the floor, which steps should he perform to collect the saliva sample? Package the swab in a paper envelope. Moisten a sterile cotton swab with distilled water. Gently rub the stain, covering the entire swab. Allow the swab to dry thoroughly. Shake off the excess water.

Answers

Answer:

-Moisten a sterile cotton swab with distilled water.

-Shake off the excess water.

-Gently rub the stain, covering the entire swab.

-Allow the swab to dry thoroughly.

-Package the swab in a paper envelope.

Explanation:

Answer:

Moisten a sterile cotton swab with distilled water.

-Shake off the excess water.

-Gently rub the stain, covering the entire swab.

-Allow the swab to dry thoroughly.

-Package the swab in a paper envelope.

Explanation:

Explanation:

Regulatory proteins often must be bound to a ____ regulatory element to switch a gene on.

Answers

Regulatory proteins often must be bound to a cis-regulatory element to switch a gene on (activator), or to turn a gene off (repressor). ... Enhancers are sites on the DNA strand that are bound by activators in order to loop the DNA, bringing a specific transcription factor to the initiation complex.

in your opinion
when you exercise vigorously, what is needed more: food or oxygen? Why?

Answers

Answer:

oxygen because

Explanation:

because u  can survive 3 days with out it  and if u did not have oxygen u would suffocate

I can exercise if the last time I ate food was 3 days ago. I can’t exercise if the last time I took a breath was 3 days ago. You need it or else you will pass out. I cannot even exercise vigorously if I stop breathing for a minute. My body will need oxygen and I will faint. You need to keep breathing at all times.

Please help me please

Answers

Answer:

cloud, water, rain

Explanation:

How can you help others practice positive healthy choices?
exercise with them
share reliable health resources with them
participate with your friends in healthy community events
O
all of the above

Answers

all of the above mark me branliest is this helps

Answer:

all of the above

Explanation:

which two sentences describe how meiosis differs from mitosis?
A. Meiosis produces cells with double the number of chromosomes of the parent cell.
B. Meiosis produces either male or female gametes.
C. Meiosis produces cells with half the chromosomes of the parent cell.
D. Meiosis produces cells that are genetically identical to the parent cell.

Answers

B and C, because meiosis produces haploid cells (23 chromosomes) and boys and girls use meiosis to produce gametes.

LAST QUESTION OF THE NIGHT, rly want to sleep lol! Someone know the answer or no?

Answers

Aa or AA, white means she is unaffected, it’s a recessive trait, so it means she doesn’t have it, so it can’t be aa

Which statement best describes behavioral adaptations?

Answers

Answer:

I don't know what the options are, but i can give an example that may help you.

Examples:

- Kangaroos lick their arms to stay cool

- Kangaroos search for food at night, when the temperature is much cooler.

Was the answer above me correct??

True or False -water vapor can condense in the air creating clouds and fog

HELPPPP PLEASE!!!!​

Answers

Answer:

True! Hope this helps!! (:

Explanation:

What is homeostasis?
a. production of urine.
b. maintaining a stable internal environment.
excretion of waste materials.
d. none of the above.

Answers

B- maintaining a stable internal environment.

Answer:

I believe the best answer is B.

Explanation:

Homeotasis is a process by many different organisms used to maintain stability in the body.

The time it takes for a wave to reach its destination is called the?
Frequency
Wavelength
Speed of light

Answers

Answer:

I believe that it is Wavelength

How it is the answer:

It is Wavelength because it is the length of the electromagnetic waves are being broadcasted so the reasonable answer would be Wavelength because it is the length of time the electromagnetic waves is taking.

Apparent brightness depends on which two properties?
A. Luminosity and distance
B. Luminosity and temperature
C. Distance and temperature
D. Luminosity and size

Answers

Answer:

B. Luminosity and temperature

Explanation:

Actually it’s a , luminosity and distance

Which of the following statements is not a description of Saturn?
A. Known for its rings
B. Largest planet in the solar system
C. One of the gas giant planets
D. Has several moons

Answers

Answer:

B) largest planet in the solar system

the largest planet in the solar system is Jupiter.

Answer:

The answer that I got is B) largest planet in the solar system

Explanation:

What is stage 2 of mitosis

Answers

Answer:

Metaphase

Explanation:

Metaphase is when the sister chromatids line up in the middle with fibers attached to each end.

is a phone a potential or kinetic energy?

Answers

Answer:

id.k if this will help but here

Explanation:

Type of kinetic energy that powers a cell phone: Electric energy

A basketball held over your head has this: Gravitational/ potential energy

Space that contains no matter: Vacuum

Anything in motion has this: Kinetic energy

Potential energy is the correct answer because inside of a phone there is a battery that contains potential chemical energy
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