If you were traveling from Monterey on the California Coast to visit Yosemite National Park, on the eastern side of the state, what three major land forms would you pass through? (in order)
A) The Klamath Mountains, the Cascade Range and the Modoc Plateau.
B) The Transverse Ranges, the Mojave Desert and the Great Basin.
C) The Coast Ranges, the Central Valley and the Sierra Nevadas.
D) The Central Valley, the Sierra Nevadas and the Great Basin.

Answers

Answer 1

The Sierra Nevada and Coast Mountain Ranges fall and elevate by a few millimeters each year. As a result of winter rains and summer groundwater pumping in California's Central Valley. Thus, option C is correct.

What three major land forms in California?

According to calculations by a group of geophysicists, gradual depletion of the Central Valley aquifer caused by groundwater pumping also raises these mountain ranges by a comparable amount each year.

Roughly the thickness of a dime—with a cumulative rise over the past 150 years of up to 15 centimeters (ca. 6 inch).

Therefore, The Coast Ranges, the Central Valley and the Sierra Nevadas. putting stress on the state's faults and raising the possibility of an earthquake.

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Related Questions

antimicrobics effective against only gram-positive bacteria would be termed antibiotics. narrow-spectrum drugs. semisynthetic drugs. synthetic drugs. broad-spectrum drugs.

Answers

Antimicrobics effective against only gram-positive bacteria would be termed narrow spectrum antibiotics. Thus the correct answer is option (A).

In the fight against bacterial illnesses, antibiotics have become a necessary component of daily life for humans. They are categorized based on the range of bacteria that they attack.

The narrow-spectrum antibiotics, as their name implies, target a particular germ for treatment. When the etiological organism is identified, these drugs target certain infections. They won't kill as many germs as broad-spectrum antibiotics, but they will get rid of the specific bacteria that are the source of that illness.

The complete question is:

Antimicrobics effective against only gram-positive bacteria would be termed ____________ antibiotics.

(A). narrow-spectrum drugs.

(B). semisynthetic drugs.

(C). synthetic drugs.

(D). broad-spectrum drugs.

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if natural selection is the only force acting on this population from generation to generation, what do you predict will happen to allele frequencies over successive generations?

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Microevolution, or a change in allele frequencies over time, can be brought on by natural selection, with fitness-increasing alleles becoming more prevalent in the population over the course of generations.

Microevolution may result from natural selection. The phenotype, or visible characteristics, of an organism is affected by natural selection. Often, genotype largely determines phenotype (the alleles, or gene versions, the organism carries). Natural selection can raise the frequency of the beneficial alleles from one generation to the next, or it can generate microevolution, where a phenotype produced by certain allele.

Example: rabbit's fur color

A population evolves via natural selection:

In comparison to their counterparts, organisms with heritable genetic traits that aid in their ability to survive and reproduce in a certain environment tend to create more offspring. The population will eventually acquire more heritable features that aid in reproduction and survival if this continues over numerous generations. The population generation will change in terms of its genetic make-up and inherited qualities, but it will also change in a way that makes it more suited to its environment.

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the frequency of a recessive allele in a population is 50%. what is the frequency of the dominant allele?

Answers

The frequency of a dominant  allele in a population is 0.75. If the frequency of a recessive allele in a population is 50%.

Given

Frequency of recessive allele in percent  q² = 50%

q = 0.5

From Hardy Weinberg principle

if no unfavorable factors exist, genetic variation in a population will remain stable from one generation to the next.

p + q = 1

p = 1-0.5

p = 0.5

Frequency of dominant allele

p² + 2pq =

(0.5)2 +2 x 0.5 x 0.5 = 0.75

Hence, frequency of dominant allele is 0.75.

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A relatively small area with numerous endemic species and a large number of endangered or threatened species is called a _________.

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Certain areas are home to numerous endemic species found nowhere else. Many of them are severely threatened by habitat loss and other human activities. These regions are biodiversity hotspots.

There are 36 locations in the world where effective species conservation can have a substantial impact on global biodiversity conservation. Areas with significant densities of endemic species (species found nowhere else on Earth) and substantial habitat loss are sometimes referred to as "hotspots" in the region and are thus naturally found there.

Endangered species are those that live in restricted habitats such as mountains, lakes, and islands. Extinction rates are exacerbated by habitat loss. Other factors include habitat loss, commercial overexploitation of animals, the introduction of hazardous alien species, pollution, and disease transmission.

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Location Four: Select two events that you predict will be observed. If I explore two oceanic plates at a convergent boundary, then I will observe:

earthquakes
faults
ocean formation
mountains
volcanoes
island chains
seafloor spreading

Answers



The earthquake, faults , ocean formation and mountains is correct

Choose any two

How many valence electrons are in the alkaline earth metal family? do they form cations or anions?.

Answers

There are 2 valence electrons in the alkaline earth metal family. They form cations.

Alkaline earth metals have two valence electrons. This means that when it reacts with other elements, it loses two electrons instead of gaining them, making it a cation or cation.

A valence electron is an electron withinside the outermost shell or strength degree of an atom. For example, oxygen has six valence electrons, withinside the 2s subshell and 4 withinside the 2p subshell.

A cation is a positively charged ion. Anions are negatively charged ions. Ions are charged atoms or molecules. When a balanced atom loses one or more electrons, it becomes a positively charged cation. When a balanced atom gains one or more electrons, it becomes a negatively charged anion.

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discuss the glycoproteins and glycolipids that have terminal sialic acids on their oligosaccharide chains.​

Answers

Sialic acids (Sias) are nine-carbon atom sugars that are typically found on the cell surface as terminal residues of glycoproteins and glycolipids or secreted. They play crucial roles in cellular communication as well as in pathogen infection and survival.

The glycoconjugates (glycolipids, glycoproteins, and proteoglycans) on surface membranes help maintain water at the surface of cells because they contain sialic acid-rich oligosaccharides.The majority of sialic acids are found in the terminal ends of glycoproteins and glycolipids, in tissue and capsular polysialic acids, and in bacterial lipooligosaccharides/polysaccharides. Sialic acids also exist in many forms that determine their function in biology.Sialic acids are essential parts of the majority of the selectin family of cell adhesion molecules' ligands, which mediate interactions between immune cells and/or involve platelets as well as leukocyte rolling along endothelium.Sialic acids (Sias) are nine-carbon atom sugars that are typically found on the cell surface as terminal residues of glycoproteins and glycolipids or secreted. They play crucial roles in pathogen infection and survival as well as cellular communication.

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in the laboratory, choice and preference are investigated by arranging schedules of reinforcement.

Answers

In the laboratory, choice, and preference are investigated by arranging concurrent schedules of reinforcement.

Concurrent schedules of reinforcement are set up in the lab to examine choice and preference. This enables scientists to investigate how and when animals make decisions between various options. We can learn more about animal behavior and environmental adaptation by comprehending how animals make decisions.

This is accomplished by offering the subject two or more options and tracking their decision-making process over time. The findings of these studies inspired Michael Murray-Slavkin, a forerunner in the field of preference testing, to formulate a theory known as "the Principles of Choice."

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Most repressor proteins are allosteric. Which of the following binds with the repressor to alter its conformation?
A) inducer
B) promoter
C) RNA polymerase
D) transcription factor
E) cAMP

Answers

Inducer binds with the repressor to alter its conformation.

What is a Repressor?

In genomics, a repressor is a protein that inhibits the expression of one or more genes. The repressor protein inhibits messenger RNA production by binding to the promoter region of the gene(s) (mRNA). Repressor proteins are required for gene expression regulation in cells.

Repressors are proteins that inhibit or reduce gene expression, as evidenced by decreased messenger RNA production from the affected gene. Repressor proteins typically work by binding to and blocking critical DNA sequences in the gene, such as the promoter, which initiates mRNA transcription. In bacteria, repressors and activators of gene expression are distinct.

However, in higher eukaryotic cells, a DNA binding protein can act as an activator or repressor of gene expression, depending on its interactions with other proteins in the cell or other cellular context. Other molecules, such as non-coding RNA, may also act as repressors.

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vesicle formation is driven by the binding of clathrin or cop proteins. select an answer and submit. for keyboard navigation, use the up/down arrow keys to select an answer. a true b false

Answers

It is true that vesicle formation is driven by the binding of clathrin or COP proteins.

Vesicle formation is used to recycle membrane components and allow extracellular substances to enter the cell. Thus, endocytosis and a variety of cellular functions are linked to vesicle formation.

The majority of transport vesicles originate in specialized, membrane-coated regions. They emerge as coated vesicles with a distinct cytosolic surface cage of proteins.

Coated vesicles can be broken down into three distinct categories based on the coat proteins they contain:clathrin-covered, COPI-covered, and COPII-covered vesicles. In the cell, different transport steps rely on each type.

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to study the maximum amount of genome diversity in humans, which of the following provides the most information?

Answers

To study the maximum amount of genomic diversity in humans using SNP variation

Human diversity can be seen through physiological analysis, namely through the genetic material in each person which gives different characteristics. Genetic material will be sequenced through a sequencing process and then mapped to the human genome database. Many factors cause human diversity such as climate and region.

SNP variation is a genetic variation indicated by a single nucleotide difference. This variation is one of the most common forms of human genetic variation. By using SNP variations we can study the differences in members of a biological species from one another.

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once sars-cov-2 genome enters into human host cells, the host rna dependent rna polymerase enzyme will copy viral rna into new rna copies to eventually be packaged into new viruses.True or False

Answers

The given statement that sars-cov-2 genome replicates into the host cell is true. It is the property of the RNA dependent RNA polymerase enzyme to replicate the genome as well as carry the transcription.

The SARS-CoV is a novel coronavirus with a big, positive-sense, single-stranded RNA that is roughly 30 thousand nucleotides long and has 14 functional open reading frames (ORFs), of which 2 major ORFs make up the replicase gene, which encodes the proteins needed for viral RNA synthesis. The entire SARS-CoV-2 genome encodes a polyprotein of roughly 7096 residues, including both structural and non-structural proteins (NSPs). Two non-structural proteins, ORF1a and ORF1ab, together with structural proteins, hold the majority of the nucleotide content of the viral genome. Spike glycoprotein mediates the entrance of the coronavirus into host cells (S protein). The homotrimers of the transmembrane spike glycoproteins protrude from the viral surface. Since the spike glycoprotein is essential for coronavirus entrance, it is a desirable antiviral target. The S1 and S2 subunits are two functional subunits that make up the S protein.

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In relation to their position in a food chain, what do plants and photosynthetic algae have in common?.

Answers

Plants and photosynthetic algae both are producers in relation to their position in a food chain.

Producers also termed as autotrophs, they make their own food. They are on the first position of every food chain. Plants and photosynthetic algae are the organism that can produce their own food by using the materials from organic sources, like- sunlight, carbon dioxide etc. Therefore, they can be called as producers or autotrophs in relation to their position in a food chain. They formed the base of an energy pyramid of ecosystem.

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A chemist, during the course of an analysis, runs across a chemical that he determines to be composed of a 1:2:1 ratio of carbon, hydrogen, and oxygen. It is probably

A-An ATP molecule

B-An amino acid

C-A fatty acid

D-A monosaccharide

Answers

The answer is D-A monosaccharide

which of the choices below determines the direction of gases moving across the respiratory membrane? group of answer choices the temperature partial pressure gradient molecular weight and size of the gas molecule solubility in water

Answers

Partial pressure determines the direction of gases moving across the respiratory membrane.

A gas will circulate from a place in which its partial strain is better to a place in which its partial strain is lower. In addition, the extra the partial strain distinction among the 2 areas, the greater speedy is the motion of gases.

There are also other factors such as membrane thickness, membrane surface areas, diffusion coefficient and many others.

Out of the given options, partial pressure is the correct choice as it determines the direction of gases.

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What is the difference between a musculoskeletal disease and a musculoskeletal disorder.

Answers

Answer:

A disease is an illness that is suddenly acquired, and a disorder is present at birth.

Explanation:

Musculoskeletal discomfort has a wide range of reasons. The wear and tear of daily activities can cause muscle tissue injury.

Musculoskeletal discomfort can also be caused by trauma to a region.

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when using the crispr-cas9 system to make a mutation in a cell, the guide rna will contain which sequences (or complementary versions of the sequence):

Answers

While using the crispr-cas9 system to make a mutation the sequence required is 20 bases sequence.

In an ordinary CRISPR study, an sgRNA is designed to have a manual collection domain (specific as gRNA in our study) on the 5′ end, that is complementary to the goal collection.

The rationally designed sgRNA is then used to manual the Cas9 protein to precise webweb sites withinside the genome for centered cleavage.Better concentrated on of CRISPR-Cas9In maximum instances the manual RNA includes a particular collection of 20 bases. These are complementary to the goal collection withinside the gene to be edited. However, now no longer all 20 bases want to suit for the manual RNA as a way to bind.

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a new strand of dna is made. write the name of the process and the main enzyme involved. process is called : enzyme that adds new nucleotides is called:

Answers

Replication is the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules. DNA replication involves DNA polymerase enzyme to add new nucleotides.

Our genome contains approximately 333 billion base pairs of DNA, all of which must be precisely duplicated each time one of your trillions of cells divides.

Semiconservatism applies to DNA replication. The double helix's individual strands serve as templates for the creation of new, complimentary strands. DNA polymerases, which require a template and a primer (beginning) and synthesis DNA in the 5' to 3' orientation, are the enzymes responsible for creating new DNA. One new strand of DNA is created as a single continuous unit during DNA replication. The other is composed of tiny fragments. DNA primase, DNA helicase, DNA ligase, and topoisomerase are other enzymes necessary for DNA replication in addition to DNA polymerase.

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Classify the carbohydrate tagatose by both the carbonyl group and the number of carbon atoms.

Answers

Ketohexoses the carbohydrate tagatose by both the carbonyl group and the number of carbon atoms.

Class of naturally occurring substances and derivatives created from them known as carbohydrates. Early in the 19th century, it was discovered that materials like wood, starch, and linen were primarily made of molecules with the general formula C6H12O6, which contained atoms of carbon (C), hydrogen (H), and oxygen (O).

Six-carbon monosaccharides known as ketohexoses include fructose, psicose, sorbose, and tagatose. Due to their thermolability, these compounds have been studied utilising our LA-CP-FTMW spectrometer, which requires the use of a laser ablation source to convert solid samples into gaseous forms.

Despite having a linear structure, ketohexoses quickly cyclize in aqueous solutions to produce combinations of pyranose and furanose forms [106]. The two enantiomers and are produced when the cyclization reaction changes the C2 in chiral carbon.

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a defective na /k atpase pump is isolated from a plasma membrane and studied. careful measurements in the laboratory determine that the pump is able to hydrolyze atp and transports 3 na ions across the plasma membrane. the pump is also able to bind 2 k with high affinity. however, the pump is unable to shuttle k ions across the plasma membrane. based on these observations, what is the most likely cause of the defect in this pump?

Answers

It is impossible for the damaged Na+/K+ ATPase to dephosphorylate itself.

The phosphorylated form of the Na+/K+ ATPase has a high affinity for K+ ions and a low affinity for Na+ ions, and it is one of the two forms that the Na+/K+ ATPase pump alternates between. The pump releases the bound 3 Na+ ions outside the cell and binds to the 2 K+ ions from the surroundings as a result of the release of phosphate from ATP and phosphorylation of Na+/K+ ATPase. K+ ions are released inside the cell as a result of the Na+/K+ ATPase's decreased affinity for K+ ions as a result of dephosphorylation.

To attain its dephosphorylated form, a faulty Na+/K+ ATPase must be able to select and bind K+ ions but not transport them across the membrane. If phosphate were not released, the pump's affinity for K+ ions would not be lowered and it would not be able to release them to the other side of the membrane.

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Ecological Succession: The process by which the ecosystem _________________________________________ from barren land to a complex ecological community.

Answers

Ecological Succession: The process by which the ecosystem colonization of species from barren land to a complex ecological community.

What is Ecological Succession?

The process through which a region's species and habitat mix changes over time is known as ecological succession. These communities gradually take the place of one another until a "climax community"—such as an established forest—is attained or until a disruption, like as a fire, happens. The notion of ecological succession is important to ecology.

A dirt field, for example, is ploughed and left for the summer. Weeds begin to sprout on the field throughout the summer. Small bushes begin to develop once the weeds have grown. Trees begin to sprout in the field after a few years.

Ecological Succession: The process by which the ecosystem colonization of species from barren land to a complex ecological community.

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a prokaryotic cell is found in an environment that has high salinity and a cell wall composed of polysaccharides. it must be

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A prokaryotic cell is found in an environment that has high salinity and a cell wall composed of polysaccharides must be archaea.

In the field of biology, archaea can be described as prokaryotic organisms that include some type of species that have the ability to survive in extreme conditions such as high salinity. Such archaea that can survive in high salinity conditions are referred to as halophiles.

The archaea also have a cell wall that is made up of polysaccharides rather and the plant cell wall is made from phospholipids.

Not all species of archaea can live in high-salinity environments. Some of the species that live in oceans especially can survive in saline conditions.

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would you expect a plant living in a very dry environment (desert) to have leaves with a high surface area to volume ratio or a low surface area to volume ratio? to retain heat would an organisms more likely have a high surface area to volume ratio or a low surface area to volume ratio? how about for respiration?

Answers

Low surface area to volume ratio in a dry atmosphere . Low surface area to volume ratio to retain heat for respiration, organisms with a high surface area to volume ratio are more likely.

Photosynthesis benefits heterotrophs in a number of ways. They rely on the process for producing oxygen, which is created as a byproduct of photosynthesis. Furthermore, photosynthesis supports the autotrophs on which heterotrophs rely for survival.

Because many species have comparable genes regardless of the habitat they are in, gene flow among populations decreases the opportunity for local adaptation within each group.

The plant's large surface area allows it to absorb as much sunlight as possible, which is essential for photosynthesis to produce food for the plant.

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The reaction to a stimulus is a

Answers

Answer:the reactionto a stimulus is called response

Explanation:brainiest please

Answer: The reaction to a stimulus is called response.

Explanation:

Students are comparing the functions of carbohydrates and lipids. Which cellular function would be shared between carbohydrates and lipids?.

Answers

A cellular function that is shared between carbohydrates and lipids is energy production.

Carbohydrates like glucose will be oxidized to pyruvic acid in glycolysis which gets transported to mitochondria where it gets converted to acetyl co-a. Acetyl co-a then enters Kreb's cycle in which Nadh and Fadh molecules are formed these molecules are oxidized in the electron transport chain to form ATP which is an energy currency of a cell. Lipids are oxidized through the beta-oxidation pathway to form acetyl co-a which enters the Krebs cycle to form Nadh and Fadh molecules which are oxidized in the electron transport chain to form ATP. This explains how carbohydrates and lipids share the same function which is energy production.

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as they emerge from the ribosome, signal sequences are recognized and bound by a(n) ... select an answer and submit. for keyboard navigation, use the up/down arrow keys to select an answer. a trna b signal peptidase c signal recognition particle d signal recognition particle receptor

Answers

As they emerge from the ribosome, signal sequences are recognized and bound by a signal recognition particle (SRP).

The majority of newly synthesized proteins that are destined for the secretory pathway contain a short peptide known as a signal sequence at their N-terminus. These proteins include those that are inserted into most cellular membranes, secreted from the cell, or found within specific organelles.

The mechanism by which secretory proteins are targeted to the ER during their translation (the cotranslational pathway) is as follows. A signal recognition particle (SRP) composed of six polypeptides and a small cytoplasmic RNA (7SL RNA) recognizes and binds signal sequences as they emerge from the ribosome. The signal sequences are about 20 amino acids long and typically contain hydrophobic residues near the polypeptide chain's amino terminus.

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pouches that form in the walls of the large intestine due to excessive exertion during defecation are called . group of answer choices ulcers phytobezoars diverticula hemorrhoids

Answers

Hemorrhoids in the diverticula.

What is large intestine?

Diverticula are pouches that emerge from the large intestine's outer wall.

The pancreas secretes insulin, a hormone that tells cells to take up blood sugar for use as fuel or storage when blood sugar levels rise. Blood sugar levels start to decrease as cells begin to absorb it.

Blood glucose levels increase when we eat. By directly stimulating the cells in skeletal muscle, cardiac muscle, and adipose tissue to take up glucose from the blood, this causes the pancreas to generate the vital hormone insulin.

Physiological hyperinsulinemia in healthy people entirely suppresses glycogenolysis while suppressing gluconeogenesis by 20%. With little impact on glycogen storage, hyperglycemia alone inhibits hepatic glycogenolysis.

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which organ transplant is the most susceptible to rejection and has the best graft survival rates when the organ is obtained from hla-identical, abo-compatible siblings?

Answers

HLA-incompatible organ transplant is the most susceptible to rejection and has the best graft survival rates when the organ is obtained from hla-identical, abo-compatible siblings

A gene complex called human leucocyte antigen (HLA) is responsible for producing the MHC proteins in people. The control of the human immune system is carried out by these cell-surface proteins. The HLA is a crucial factor in organ transplant rejection because it causes the body to create antibodies when the organ from the donor is recognized as non-self.

In identical twins, HLA is identical. Therefore, twins, siblings with some similarity, followed by a parent with some similarity, are the top choices for transplantation. If a family member cannot donate, an unrelated donor will be given the least preference. Therefore, Twin>Sibling>Parent>Unrelated donor is the right order of chances of successful transplantation.

Hence, chances of HLA-incompatible organ transplant success lies in closeness of patient to donor.

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osteocytes are surrounded by a dense, bony matrix. how do they get the nutrients they need to survive?

Answers

Osteocytes can enter blood vessels and deliver nutrients to the bone. On the other hand, osteoclasts degrade the matrix and release the resulting products into the blood.

Osteocytes receive nutrients through their dendrites, which are tentacle-like structures that extend through tiny structures called canaliculi. Because they make up 95% of the cells in adult bones and aid in the formation of bone, osteoclasts require nutrients.

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Which action is one role of RNA polymerase during transcription

A. To break down an already existing protein

B. To produce a start sequence

C. To switch uracil with thymine on the exposed gene

D. To build a molecule of mRNA

Answers

Answer:

D) To build a molecule of mRNA

Explanation:

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It is D! I took this test
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when taking a health history of a 5-year-old boy who recently was found to have type 1 diabetes, the nurse would anticipate which reaction from the child? discuss how punishment and negative reinforcement differ, and list some drawbacks of punishment as a behavior-control technique Which unique feature of e-commerce is related to the ability to interact with web technology everywhere?. hey I wrote an essay can somebody read over it and see if I need to change anything Hi my name is Madelyn Wayne and I used to take electricity for granted then my life went upside down let's just rewind 1 month ago THROW IT THROW IT THROW IT !!, Alexandra yells. It's the bottom of the ninth and 1 point away from winning. I GOT IT I GOT IT!, I shout back. BAM the softball hits me in the head. The world is spinning like it is going down the drain. I fall to my knees and then the ground rushes up to meet me. WAKE UP, someone says. my eyes crack open. a man stands there in weird shoes. 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Parris especially concerned? What seems to worry him? who would you identify as the most likely entrepreneur? (vs. self-employed, managers, freelancers, or so on) Benson, incorporated manufactures a single product and uses the plantwide overhead rate method. The company's plantwide overhead rate is $25 per machine-hour (mh) used. Their single product uses 10,000 mh, has direct material cost per unit of $10. 96 and direct labor cost of $3. 84 per unit. The total overhead cost is expected to be: in the electrolysis of water, how long will it take to produce 9.37 mol h2 in an electrolytic cell through which the current is 74.0 ma? Once you set a ball rolling in a frictionless bowling alley, the force needed to keep it rolling is?. which of the following statements about alcohol is correct? which of the following statements about alcohol is correct? women absorb about one-third more alcohol than men because women have fewer stomach enzymes that break down the alcohol prior to absorption. on an empty stomach, alcohol can be absorbed through the lining of the stomach. alcohol does not need to be digested before it can be absorbed. all of these statements about alcohol are true. a portfolio has 45% of its value in ibm shares and the rest in microsoft (msft). the volatility of ibm and msft are 33% and 35%, respectively, and the correlation between ibm and msft is 0. what is the standard deviation of the portfolio? whta are the factors which affects the health status of india? A company currently uses passwords for logging in to company-owned devices and wants toadd a second authentication factor. Per corporate policy, users are not allowed to have smartphonesat their desks. Which of the following would meet these requirements?(A). Smart card(B). PIN code(C). Knowledge-based question(D). Secret key you have just delivered a premature baby. your assessment reveals that he is breathing adequately; however, his heart rate is 90 beats/min. you should how would you explain the difference between qualitative and quantitative data sources? how would you explain the difference between qualitative and quantitative data sources? the nurse is completing a sleep history on a client who reports sleeping problems. which of the client's regular behaviors will cause the client to have difficulty with sleep? a perfume bottle has a straw the goes from the nozzle into the fluid. the other end of the nozzle is connected to a bulb that when squeezed pushes air out. explain how the perfume makes its way out of the bottle given this configuration. Dont even know where to start! Please help with an explanation, thanks! :)