Identify all statements that accurately describe the structure of the pyruvate dehydrogenase (PDH) complex. E2 contains three domains. The complex contains multiple copies of each of three enzymes. A regulatory kinase and phosphatase are part of the mammalian PDH complex. The core of the complex is made up of several copies of E1 . Several copies each of E1 and E3 surround E2 .

Answers

Answer 1

Answer: The statements that correctly describe the structure of pyruvate dehydrogenase (PDH) complex are:

--> E2 contains three domains.

--> A regulatory kinase and phosphatase are part of the mammalian PDH complex.

--> Several copies each of E1 and E3 surround E2 .

Explanation:

Enzymes are proteins that speeds up a metabolic reaction by lowering the amount of energy needed to start the reaction. The type of enzyme in a cell will determine the metabolic processes that will occur in it.

Pyruvate dehydrogenase complex which is located at the mitochondria matrix, is a group of enzyme that catalyzes the breakdown of pyruvate, which is the end product of glycolysis, to form acetyl-CoA. The product formed from the reaction which is acetyl-CoA in turn enters the citric acid cycle where it is further oxidized for cellular respiration.

The structure of Pyruvate dehydrogenase complex consists of:

--> Three catalytic enzymes: These include;

• E1: This is the first enzyme of the PDH complex called pyruvate dehydrogenase. It catalyzes the removal of one carbon atom from pyruvate which leads to the production of hydrohyethyl.

• E2: This is the second enzyme of PDH complex called dihydrolipoamide S-acetyltransferase. It catalyzes the transfer of hydroxyethyl group to oxidized form of covalently bound lipoamide, and the resulting acetyl group is then transferred to free coenzyme A to form ACETYL-CoA and reduced dihydrolipoamide. Several copies each of E1 and E3 surround E2 and it consist of three DOMAINS. These domains include: N-terminal 9 kDa lipoyl domain, 4 kDa peripheral subunit-binding domain and C-terminal 28 kDa catalytic (acetyltransferase) domain.

• E3: This is the third and last enzyme of PDH complex called the flavoprotein dihydrolipoamide dehydrogenase. It re-oxidizes the lipoyl group of dihydrolipoamide-E2 to form lipoamide-E2 and NADH.

--> Two regulatory enzymes: The activities of E1 which is the rate limiting step of PDH complex regulated by phosphatases (activators) and kinases (inhibitors).

--> A binding protein: these aids in the binding of E2 to E3 enzyme in the core of PDH complex.


Related Questions

If dogs has 78 chromosomes in each somatic cell, how many chromosomes does each dog sperm have?

Is it possible for 2 dog spend cells to simultaneously enter a dog egg? Why or why not?​

Answers

Answer:

1.Normal dog semen contains 300 million to 2 billion sperm. The quantity of sperm varies depending on the weight and size of your dog, with the bare minimum sitting at around 10 million sperm cells per pound of bodyweight.

2.yes because The heat cycle of the female lasts from 18 to 21 days. ... Eggs remain fertile for about 48 hours. ... Dogs mature sexually earlier than they do emotionally.

Factors that control traits are called?

a. genes.
b. purebreds.
c. recessives.
d. parents

Answers

Answer:

A. Genes

Explanation:

PEASE HELPPP!!!

Identify the individual(s) in the Jones family whose genotype cannot be determined with the certainty (A_?)

Answers

We'd need to know if the trait is dominant or recessive. In other words, is the colored in A_ or aa?

which type of bond forms between water molecules

Answers

Answer:

hydrogen bonds

Explanation:

Hydrogen bonds form between neighboring hydrogen and oxygen atoms of adjacent water molecules.Attraction between individual water molecules creates a bond known as a hydrogen bond.

Answer:

hydrogen bonds.

Explanation:

In the case of water, hydrogen bonds form between neighboring hydrogen and oxygen atoms of adjacent water molecules. The attraction between individual water molecules creates a bond known as a hydrogen bond.

2.The horned lizard is often called a horned toad because of its short, fat body and small tail.

When this lizard finds a coyote, it will spray blood from its eyes at the coyote. Then the lizard will run a short distance and stay very still to blend into the background.

Why does the horned lizard do this?Lector inmersivo
(1 Punto)

Horned lizards do this to play with the coyote.

Horned lizards do this to attract other horned lizards.

Horned lizards do this to catch and eat the coyote.

Horned lizards do this to escape from the coyote.

Answers

The answer is Horned lizards will do this to escape from the coyote

For BRAINLIST
A squid is shown in the diagram.

Which structure is labeled X?


A mantle
B foot
C radula
D gill

Answers

Answer:

mantle i believe the answer should be mantle

Answer:

Mantle~

Explanation:

~~

Which of the following are similarities between meiosis and mitosis?
Check all that apply.
2 points
There are two rounds of division
DNA gets replicated during S stage of interphase
prophase, metaphase, anaphase, and telophase occur in that order
four haploid daughter cells are produced

Answers

Answer: DNA gets replicated during S stage of interphase

prophase, metaphase, anaphase, and telophase occur in that order

four haploid daughter cells are produced

Explanation:

3. In most cells,
directs the production of a
which then enters a ribosome. The
molecule of
ribosome produces the final product,
Retroviruses do the opposite. They use the enzyme reverse
transcriptase to use a template of
to produce

Answers

Answer:

In most cells, DNA directs the production of a molecule of mRNA which then enters a ribosome. The ribosome produces the final product, a protein. Retroviruses do the opposite. They use the enzyme reverse transcriptase to use a template of mRNA to produce DNA.

Explanation:

The central dogma of molecular biology describes how a cell uses its genetic information to synthesize a protein. The first step called 'transcription' consists of using an RNA polymerase enzyme and a fragment of DNA (i.e., gene) as a template to synthesize an RNA molecule, usually a messenger RNA (mRNA). Subsequently, the genetic code in the mRNA sequence is read by the ribosomes in order to produce a protein, a process known as 'translation'. Retroviruses are viruses that have the ability to integrate into the host genome by using a reverse transcriptase enzyme that allows reverse transcription of mRNA to complementary DNA, which then integrates into the host's genome.

The correct options in the blanks are DNA, mRNA, Protein, mRNA, and DNA respectively.

What is gene expression?

It is the process by which cells produce protein from DNA molecules. DNA produces RNA which contains codes to produce amino acids.

The mRNA enters the ribosome which produced protein using the codons of mRNA.

Retroviruses have special machinery to produce the DNA from mRNA.

Therefore, the correct options in the blanks are DNA, mRNA, Protein, mRNA, and DNA respectively.

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((I need the punnet square but not sure how to make it))​

Answers

Answer:

i don't know why but you probably don't want to go to the link... sorry

Answer:

Explanation:

Okay, so the female's eyes will be Xx because she carries it and I am not sure if the male is a carrier as well or not so if he is it will be Xx on the top and Xx on the side of the male is not then it will be XX and Xx and it does not matter which is on top which is on the bottom. If the male is a carrier then the outcomes will be XX, Xx, Xx, xx so they will have a 1:4 chance of getting white eyes if the male is NOT a carrier then it will be XX+Xx = XX, XX, Xx, Xx with no chances of having white eyes

PLEASE HELP!!! WILL GIVE BRAINLIEST!!!

Answers

Answer:

the answer is B

Explanation:

As it releases so does the potassium ions

What cell is this ?

Answers

Answer:

Animal cell

Explanation:

GIVING AWAY 18 POINTS PLEASE HELP ME ASAPPP!!!

Answers

Answer:a major ecosystem defined by distinctive geography and receiving uniform solar radiation and moisture

Explanation:

Mrs. Essy is type "A" and Mr. Essy is type "O." They have three children named Matthew, Mark, and Luke. Mark is type "O," Matthew is type "A," and Luke is type "AB." Based on this information:
A. Mr. Essy musy have the genotype??
B. Mrs.Essy must have the genotype??

Answers

Answer:

A) Mr Essy genotype is OB

B) Mrs Essy genotype is OO

Explanation:

A) Mr Essy genotype is OB

B) Mrs Essy genotype is OO

OO * OB

OO, OO, OB, OB

is not sleeping bad for u
hi I didnt sleep for 16 hours and I have messed up sleep pattern
will i commit no alive

Answers

No many people stay awake for 16 hours or more the only time you should be concerned is if you younger than the age of 13 try to sleep if you can try to get atleast 4 hours if any at all

Answer:

It depends. 16 hours is a long time not to sleep. You need to sleep though. Your body needs at least 8 hours of sleep. But you need at least 5 to 6 hours of sleep. So your body can regenerate itself.

Explanation:

which of tbe following are MAINLY energy sources? Choose all that apply
A. protein
B. glucose
C. triglyceride
D. amino acid
E. amylose

Please help and No Links!

Answers

Answer:

A,D,B

Explanation:

Which statement best explains the economic drawback of using geothermal energy over energy generated by fossil fuels?
More cost-effective over time
Higher installation costs than fossil fuel plants
More energy plant locations available
Less pollution than fossil fuel plants

Answers

Answer:

More cost-effective over time

Answer:

Could it be the higher installation costs than fossil fuel plants????

Explanation:

A directional flow of electric charge

Answers

Answer:

The direction of an electric current is by convention the direction in which a positive charge would move. Thus, the current in the external circuit is directed away from the positive terminal and toward the negative terminal of the battery. Electrons would actually move through the wires in the opposite direction.

Conventionally, a positive charge would go in the same direction as an electric current. As a result, the battery's positive terminal receives less current in the external circuit than its negative counterpart. Actually, electrons would go in the reverse direction across the cables.

What is electric current ?

A stream of charged particles, such as electrons or ions, traveling through an electrical conductor or a vacuum is known as an electric current. The net rate of electric charge flowing through a surface or into a control volume is how it is calculated.

The cell phone, trains, ships, refrigerator, and the motors in appliances like food processors all run on electricity. To be useful, electric energy must be converted into other forms of energy like heat, light, or mechanical.

Conventionally, a positive charge would go in the same direction as an electric current. As a result, the battery's positive terminal receives less current in the external circuit than its negative counterpart.

Thus, a positive charge would go in the same direction as an electric current.

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An estuary collects sediments from the ocean and rivers that feed into it. The sediments swirl around and then settle to form a mudflat. Eel grass is then established on the mudflat. The ecosystem changes over time and ultimately develops into a salt marsh that contains mangrove trees.
Which of the following is likely NOT involved in this example of ecological succession?

A)
The rotting remains of plants add to the fertility of the soil.


B)
The soil becomes so fertile that eel grass is replaced by other plant species.


C)
The roots from plants help stabilize the sediment, keeping it in place.


D)
The concentration of salt becomes so high that all plant life is destroyed.

Can y'all included detail answers on why the other answers are incorrect

Answers

I’m pretty sure it’s A

In Drosophila, red eyes is wild-type and purple eyes are mutant. Full-size wings are wild-type and vestigial wings are mutant. Flies with wild-type pr pr vg vg genotypes were crossed with double mutant flies with a pr-pr- vg-vg- genotypes. The F1 flies had pr pr- vg vg- genotypes. The F1 flies with heterozygous genotypes were crossed with double mutant flies with a pr-pr- vg-vg- genotypes One thousand offspring were typed. This cross produced 430 red-eye, wild-type wing flies, 65 purple-eye wild-type wing flies, 60 red-eye, vestigial wing flies, and 445 purple-eye, vestigial wing flies. What is the distance between the loci for purple eyes and vestigial wings in centiMorgans (map units)

Answers

Answer:

Distance between genes 12.5 MU = 12.5 cM.

Explanation:

Due to technical problems, you will find the complete explanation in the attached files.

The stages of mitosis were originally defined by cellular features observable through a light microscope.

a. True
b. False

Answers

Answer: TRUE

Explanation:

The cell division that takes place during the growth and development of an organism is in an as MITOSIS. Mitosis takes place in somatic cells that is, body cells that are not involved in the production of gametes. The difference stages of mitosis were originally defined by cellular features observable through a LIGHT MICROSCOPE. These stages includes:

--> PROPHASE: when viewed under a light microscope, each chromosome shortens and thickens and is seen to consist of two chromatids. The Centriole begin to separate.

--> METAPHASE: The nuclear membrane disappears, a spindle forms, the chromosomes line up across the middle of the cell and become attached to the spindle fibres at their centromeres.

--> ANAPHASE: The sister chromatids are pulled apart to opposite ends of cell as the spindle fibres contract.

--> TELOPHASE: A nuclear membrane forms around each set of chromatids, and the cell divides into two daughter cells.

7. How does distance affect the strength of an electric force?
A. Electric forces that are closer together are weaker.
B. Electric forces that are closer together are stronger.
O C. Electric forces have the same strength regardless of distance.
O D. Electric forces create their own strength depending on their charge.

Answers

The correct answer will be A
A. Electric forces that are closer together are weaker
Explanation: Increasing the separation distance between objects decreases the force of attraction or repulsion between the objects.

Name three benefits of keeping plants at home.

Answers

Answer:

Studies have shown that indoor plants...

Boost your mood, productivity, concentration and creativity.

Reduce your stress, fatigue, sore throats and colds.

Help clean indoor air by absorbing toxins, increasing humidity & producing oxygen.

Add life to a sterile space, give privacy and reduce noise levels.

why is the air temperature in the rain forest of Peru so warm?

Answers

Answer:

Because Peru is located between the equator and Tropic of Capricorn. Since it is in the tropics, one might expect Peru to be a country of extreme heat  and heavy vegetation.

Explanation:

what stores groundwater

Answers

Answer:

An aquifer is a rock layer that stores groundwater and allows the flow of groundwater.


Ecosystems can stay stable for hundreds of years, but loss of resources or addition of disease can quickly change the dynamics of said ecosystem.
True
OFalse

Answers

True ecosystems tend to depend on some sort of aid or resource and if it goes away so will that ecosystem

Compare and contrast the outer core and the inner core. Mention 2 differences between the two cores.

Answers

Answer:

The outer core is colder than the inner core, and they are both inside the Earth. The inner core is the deepest layer of Earth's layers.

Explanation:

5. What does EGS stand for in geothermal energy?
A) Engraved Geothermal System
B) Enhanced Geothermal System
C) Exhaust Gas System
D) Engineered Geophysical System​

Answers

(EGS) stands Enhanced Geothermal Systems which can greatly increase geothermal energy utilization. Therefore, option (B) is correct.

What is EGS?

Enhanced Geothermal Systems (EGS), which are also referred to as engineered geothermal systems on occasion, present a significant opportunity for significantly broadening the application of geothermal energy.

In an EGS, fluid is injected into the subsurface under conditions that are carefully regulated. This causes previously closed cracks to reopen, which in turn creates permeability in the rock. The increased permeability of the rock makes it possible for fluid to move freely within the newly fractured rock and for heat to be transported to the surface, where it can be used to create electricity.

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how does the soil environment support the earthworm in the students hand

Answers

The soil can determine how the earthworm will react, if there’s bad soil most likely there won’t be a lot of earthworms around

PLEASE HELP FAST!!!!

As humans continued to burn more and more oil and natural resources what has happened
to the world's carbon dioxide output?

Answers

Answer:

Global warming 100%  one of them.  And Air pollution.

Explanation:

Good luck

The TAS2R38 gene encodes a receptor protein that influences the ability to taste bitterness. The gene has two alleles: a dominant, wild-type allele that enables an individual (taster) to taste bitterness and a recessive, mutant allele that interferes with the ability of an individual (nontaster) to taste bitterness. In a sample of 2,400 people, 1,482 were found to have the dominant (taster) phenotype. Assuming that the population is in Hardy-Weinberg equilibrium, approximately how many individuals in the sample are expected to be heterozygous for TAS2R38

Answers

Answer:

The correct answer is - 1133.

Explanation:

According to H-W equilibrium;

p2 +2pq + q2 = 1 ........... eq.1   and

(p+q)2 = 1 ..............eq.2

Here q = frequency of the recessive allele,

and p = frequency of the dominant allele in the population

The genotype of p2 + 2pq shows the dominant(taster) phenotype.

The genotype of q2 shows the recessive(non-taster) phenotype.

q^2 = (2400 - 1482)/2400

= 0.3825  

= 0.618

using eq. 2 we get p= 1-q

=0.382

2pq = No. of heterozygotes/2400

No. of heterozygotes = 1133.1648

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