Heparin, a highly negatively charged glycosaminoglycan, is used clinically as an anticoagulant. It acts by binding several plasma proteins, including antithrombin III, an inhibitor of blood clotting. The 1:1 binding of heparin to antithrombin III seems to cause a conformational change in the protein that greatly increases its ability to inhibit clotting. What amino acid residues of antithrombin III are likely to interact with heparin

Answers

Answer 1

Answer:

Positively charged amino acids

Explanation:

Heparin is an acid polysaccharide that has a strong negative charge due to the sulfate groups on its glucosamine residues. This negative charge confers to heparin anticoagulant activity. The negatively charged groups in the heparin molecule can interact with positively charged (basic) residues, such as arginine (Arg) and lysine (Lys) of plasma proteins. For example, it has been shown that lysine amino acid residues of antithrombin III may be involved in the binding with heparin.


Related Questions

help pleaseee

give an example of lamarcks theory of evolution:

Answers

Lamarck believed that elephants all used to have short trunks. When there was no food or water that they could reach with their short trunks, they stretched their trunks to reach the water and branches, and their offspring inherited long trunks.

how many times does a child have to be vaccinated against tetanus?​

Answers

Answer:

There are 5 doses to the tetanus shot for a child. That is what is reccommended.

Explanation:

what are the chances that a color blind man will have a color blind grandson what are the genotypes for all involved.

Answers

Answer:

Depends

Explanation:

It depends if the genotypes are hetero.zygous or resessive/dominant homo.zygous. Being colorblind could be represented by a resessive genotype like, bb. if their son/daughter has Bb or bb or their son/daughter in law has a resessive trait then having a color blind grandchild maybe possible. The colorblind grandson has parents that both have at least 1 resessive trait, then the grandson could not be colorblind.

Directions Make a list of objects, products, and any other items around your house where plants were involved in the production of the item. You should have a list of at least twenty items. Then respond to the following questions: Note: Your list of objects and the answers following should be at least 200 words in length. What if plants no longer existed on Earth? How would your life be different?

Answers

Answer:

-20 items-

Bed

Cat

Dog

desk

water

stove

oven

chair

toilet

shirt

shampoo

shoes

backpack

food

socks

paper

pencil

table

mask

towel

If Plants no longer existed on earth then there would be no way for carbon dioxide to be converted into oxygen, without oxygen animals and humans alike would die. The Worlds "Air" would be toxic for us to breathe, we need plants to survive. Without plants, animals would die of starvation, and predators would as well without substance.

AZT is a drug that is commonly used to fight HIV infection. The active component of AZT is a nitrogenous base that mimics thymine. Normal nucleotides CANNOT covalently bond to the thymine mimic. HIV's reverse transcriptase enzyme will use the thymine mimic instead of using thymine, whereas our DNA polymerase will not make this mistake. What is the most likely explanation for how AZT prevents HIV replication

Answers

Answer:

AZT works by selectively inhibiting HIV's reverse transcriptase, the enzyme that the virus uses to make a DNA copy of its RNA. Reverse transcription is necessary for production of HIV's double-stranded DNA, which would be subsequently integrated into the genetic material of the infected cell to produce its proteins. All reverse transcriptase inhibitors are analogues of the naturally occurring deoxynucleotides needed to synthesize the viral DNA and they compete with the natural deoxynucleotides for incorporation into the growing viral DNA chain.

The first unstable compound formed during C3 cycle is:
(a) 3-carboxy,2-keto, 1,6 bi phosphorobitol
(c) 2-carboxy,3-keto,1,5 biphosphorobitol
(b) 2-carboxy,3-keto,1,5-biphosphorobitol
(d) 3-carboxy,3-keto, 1,6-biphosphorobitol​

Answers

Answer:

(b) 2-carboxy,3-keto,1,5-biphosphorobitol

Explanation:

2-carboxy, 3-keto, 1,5-biphosphorobitol is the first unstable molecule formed during the C3 cycle. Due to its instability, this molecule is quickly broken down into two molecules each containing 3 carbon atoms, called 3-phosphoglyceric acid, this breakdown is done through water in a process known as hydrolysis.

pls help on the question below

Answers

it would be #3, a turtle digging a hole to lay eggs
answer:
#3

step by step:

What characteristic could provide a species with a better chance of surviving a drastic environmental change?

(A) A small population size

(B) A highly diversified gene pool

(C) specialized cells within the body

(D) Many individuals with the recessive trait

Answers

the answer is B


Species with a limited variety of phenotypes and where all members of the species are similar to one another have a smaller chance of coping with environmental variability compared to a species with greater diversity.

A highly diversified gene pool could provide a species with a better chance of surviving a drastic environmental change. So, the correct option is B.

What is Diversified Gene pool?

Greater genetic diversity within a population is made possible by a diverse gene pool, which raises the possibility that at least some members of the population will exhibit features that are more adapted to the new environment.

This variety can develop as a result of gene flow from other populations or mutations. The number of people having the recessive trait or a limited population size, however, would not always give an advantage in enduring environmental change. A species may have a better chance of surviving a severe environmental shift if its gene pool is extremely varied.

Therefore, the correct option is B.

Learn more about Gene pool, here:

https://brainly.com/question/1027582

#SPJ2

Labrador retrievers are traditionally black, brown, or yellow. The B allele codes for black fur, and the b allele codes for brown fur. The E allele allows the pigment to be deposited in the fur, while the e allele doesn't allow the pigment to be deposited. If one lab has the genotype bbee, and another lab has the genotype BbEe, what is the chance that an offspring will be brown

Answers

Answer:

25% of offspring will be brown

Explanation:

4 out of 16 of will be brown

to convert this to a percentage do:

4 ÷ 16 × 100 = 25

Punnett squares are in the image

Brown offspring are circled

Vascular Tissue is mostly likely to be found in the___of a plant’s shoot
- Center
- Between the center and outside
- None of these
- Outside

Answers

Vascular tissue is mostly likely to be found in the outside
Other Questions
Find the value of x. Round to the nearest tenth. 9 4 x = [?] y = 100 - 8.9x percent Which of the following details the pronunciation of the word cataract?O cat a ractO n.O a cloudy film that can develop on the eyeO [KA tuh rakt] A child gets 1 egg on their1st birthday. They get 2 ontheir 2nd, 3 on their 3rd etc.How many years will it bebefore they have received 91eggs in total? Can someone explain their answer? plz,what is memorandum Determine if the expression -z^3 + 8x is a polynomial or not. If it is a polynomial, state the type and degree of the polynomial. (Someone help me ) Use details from paragraphs 15-18 to write two or three sentences describing which days were special to the slaves and why. Cite evidence from the text to support your explanation. This is a picture of a coordinate graph.Which ordered pair describes a point that is located 4 units to the left of the origin and 6 units below the x-axis? (4, 6) (6, 4) (4, 6) (6, 4) 1. What is the health issue you want to speak about to your audience? 1 1. Thomas needs to add a sentence to the end of the second paragraph (sentences 5-9) to bring the paragraph to a more effective closing. Which of the following should be added after sentence 9 to help close this paragraph? O The basin is very different from anything I had seen before. e O We knew it was wrong to leave trash in the basin. 0 Do O The basin was a place that deserved to be saved. 0 Qo O I wanted to explore the basin the first time I saw it. O CLEAR ALL Powers not given to the federal government by the U.S. Constitution are reserved to thestates and the people. This principle is established by the -First AmendmentBFourth AmendmentEighth AmendmentDtenth Amendment 1. A person kicks a rock off a cliff horizontally with a speed of 20 m/s. It takes 7.0 seconds to hit theground, find:a. height of the cliffb. final vertical velocityC. rangeD.speed and angle of impact Because the triple beam balance is zeroed before it is put into use, it measures A. volume B. weight C. the effects of gravity D. mass a patients dose of medication increased from 100mg to 150mg. What is the percent increase in medication? The determinant of the matrix Sarah is a site investigator for a large construction firm. She is considering Miguel, a former geology student with experience as an intern at an architecture firm, for an assistant site investigation position. Which of the following is most relevant to her decision? What is Father in Japanese ? PLLLZZ HHEELLPPP! QUESTION IS BELOW! Write each percentage as a fraction in simplest form.1. 50% 2. 99% 3. 15% 4. 200%