Why is the 3-dimensional shape of a macromolecule (ex: protein) important to know from the perspective of understanding
the molecular basis of human disease? 2 pts
A/ Mutations in genes that cause a change in amino acid primary sequence can cause a change in the protein's function in a
cell. For example, it can cause the protein to mislocalize; the protein is now recruited to a specific site in the cell, like the
nucleus, where it can cause cellular dysfunction.
B/ If the protein is an enzyme, the 3-dimensional shape of the active site can be altered and decrease the rate of a reaction that
is catalyzed by that enzyme.
C/ If the protein is an enzyme, the 3-dimensional shape of the active site can be altered and increase the rate of a reaction that
is catalyzed by that enzyme.
D/ Only options A and B may be true.
F/Antions A, B and C may be true.

Answers

Answer 1

Answer:

A, B and C may be true

Explanation:

The three-dimensional structure (3D) of a protein, also known as tertiary structure, is critical to its function. In general, the 3D protein structure consists of alpha-helix and beta-sheets (secondary structures) associated through disordered coiled-coil regions. Genetic mutations may cause modifications in the 3D protein structure by modifying amino acids that are added to the growing polypeptide chain during the process of translation. In consequence, the relationships among amino acids (i.e., the intermolecular attractive forces that hold them together) may also be altered by these mutations. In general, mutations that generate amino acid changes at the active site of the enzyme will have a deleterious effect, thereby decreasing or inactivating protein function. However, there are situations where a mutation may be beneficial and can eventually increase the rate of reaction of a protein.


Related Questions

What part of meiosis involves the splitting of 2 cells to make 4 total cells

Answers

Answer:

Meiosis II

Explanation:

During Meiosis II, the 2 cells were split into 4 cells, each with 23 chromosomes.

10. What happens when environments change and species cannot adapt?

Answers

They die out and the ones that adapt will produce offsprings with the same traits to ensure survival

BIOLOGY CIRCULATORY SYSTEM!! WILL NAME BRAINLIEST IF YOU ANSWER CORRECTLY!!

Answers

Answer:

Q1)Heart,Lungs,Arteries,Veins,Vessels

Q2)Blood vessels flow blood throughout the body. Arteries transport blood away from the heart. Veins return blood back toward the heart. Capillaries surround body cells and tissues to deliver and absorb oxygen, nutrients, and other substances.

Please mark me brainliest.

Explanation:

How are eukaryotic cell walls different from bacterial cell walls?

Answers

Bacteria cell walls provide structure like plant cell walls. Unlike plant cell walls, however, the bacterial cell wall is responsible only for the one-celled organism itself, without the requirement of connecting and supporting a larger organism composed of many cells

Which of the following is an inherited trait?


A. Freckles
B. Being a good reader
C. A birthmark
D. A scar

Answers

Answer:

A. freckles

Explanation:

inherited traits are things you are born with that resemble your parents like freckles, color hair and skin even eyes and other such things

The inheritance of traits depends on the genes, not on the somatic cells. In the given choices, freckles are inherited from parents to offspring.

What are freckles?

Freckles are caused by either sun or by genes. The presence of this can be due to the genes carrying it.

Genetics and sun exposure is the main cause of freckles. There are a number of genes involved, and they can interact with one another in lots of different ways.

Somatic variations are not likely to get inherited.

Thus, the correct option is A.

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what is the cause of down syndrome

Answers

Answer:

there is multiple causes is this an acual question??????

Explanation:

give the correct biological term for the following programme where members of the community help patients take their medicines regularly​

Answers

Answer:

Explanation:

Supervised treatment

You are studying a new gene "X" that you think controls skin color in Bearded Dragons. In order to determine what gene X does you need lots of gene X DNA to work with. So, you decide to amplify it through the process known as PCR. You have a forward and a reverse primer that have been designed to gene Xf – a gene in frogs that is similar to the one found in the Bearded Dragon. You are pretty sure that these two primers will work in Bearded Dragons, so you decide to go ahead with the PCR. In frogs, the Forward Xf primer binds gene Xf between nucleotides 32 and 47. The Reverse Xf primer binds between nucleotides 1110 and 1135. What size PCR product would these two primers create if they amplified the frog gene Xfp

Answers

Answer:

The correct answer is - 1103 bp.

Explanation:

PCR or polymerase chain reaction is a process that uses a primer to amplifying the desired segments of DNA molecules. It is a technique that can amplify a million copies of the DNA segment.

given:

forward primer binds from - 32 to 47

reverse primer binds from - 1135 to 1110

PCR product would be between - 32 to 1135

So, product size would = 1135-32 = 1103.

Thus, the correct answer is - 1103.

What is the function of the circulatory system. I forgot!

Answers

Answer:

to pump blood throughout the body

Answer:

to pump blood throughout the body

Explanation:

The circulatory system contains of arteries and veins that help blood travel throughout the body

What is fermentation? Select all that apply.
process that breaks down larger molecules
into smaller molecules
process that uses oxygen to create usable
energy for the body
process that does not rely on the presence of
oxygen
process that creates waste products

Answers

Answer:

Option One

Option Three

Option Four

Explanation:

Fermentation is the process of breaking down substances different types of bacteria or microorganisms will producing heat, this process can also be completed without the usage of oxygen. Finally, fermentation is used to create alcohol like wine or beer which is considered wastes to the body. Therefore options one, three, and four are your answers or "process that breaks down larger molecules  into smaller molecules, energy for the body process that does not rely on the presence of  oxygen, and process that creates waste products."

Hope this helps.

How does the process of binary fission work in the asexual reproduction of bacteria?
A. Two cells join to become one larger cell
B. One cell splits into two cells with identical DNA.
O. DNA material from the environment is added to the cell.
D. Bacteria can only reproduce via sexual reproduction, not asexual reproduction,

Answers

The answer is B ❗️❗️❗️❗️❗️❗️❗️❗️❗️❗️

The process of binary fission work as 'one cell splits into two cells with identical DNA. in the asexual reproduction of bacteria'.

So, option B is correct one.

What is binary fission?The simplest meaning of binary fission is division into two. The binary fission is the most common methods of asexual reproduction.In biological , division of single entity into two or more parts and regenerates of these parts again and each parts have potential to grow to the size of the original cell.Binary fission occurs in Amoeba which is unicellular organismThe binary fission is type of asexual reproduction.

What is asexual reproduction of bacteria

The bacteria is prokaryotic organisms that reproduce asexually and bacteria is mainly reproduce by binary fission in which single cell divides into two .

There are some bacteria which divides in every 10 to 15 minutes .

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The blue people of Troublesome Creek Kentucky were genetically isolated from the rest of the world for generations. A rare recessive allele that causes people to have a blue tone to their skin, methemoglobinemia, became disproportionately common within this population by way of their genetic isolation. In the last few decades new roads opened leading to the end of this communities isolation. To the surprise of many, the methemoglobinemia phenotype disappeared along with their genetic isolation. Which of the following may best explain the apparent disappearance of this once common trait?

a. Methemoglobinemia did not confer any physical advantage so that the trait was selected against.
b. Methemoglobinemia was probably lethal and all those that carried this trait died and did not have a chance to pass on this trait to future generations.
c. Those that had the traits simply did not have descendents.
d. With the end of genetic isolation gene flow took place.

Answers

Answer:

The correct answer would be - d. With the end of genetic isolation gene flow took place

Explanation:

It is given that people of Troublesome Creek Kentucky were isolated and have a rare recessive allele that results in a blue tone to their skin. However, later these isolated people connected with the people from outside, and due which allow them to intermate. Intermating among populations from isolated and people from outside leads to gene flow.

Methemoglobinemia was present in the isolated population as they had both recessive alleles in their genotype and other hand people from outside might have heterozygous or both dominant allele genotypes that make them free from this disorder.

Due to the intermating and gene flow, the number of heterozygous conditions rises and after many generations slowly methemoglobinemia could have disappeared due to the masked recessive allele.

Which unhealthy condition30 point would most likely result from a person eating too much food for many years?

Answers

Answer:

Conditions such as obesity, stroke, high blood pressure, heart disease, and diabetes can occur to someone who eats too much unhealthy food for many years.

22) During durg adminsteration not necesary tell
to the patient
A) Prupase of durg
B) Side effect of durg
C) Route of mrdication​

Answers

A I believe I have no idea

Which has the highest density?


A. water at 0°C

B. water at 4°C

C. water at 6°C

D. water at 8°C

Answers

Its B ( at 4 degrees) as at this temp 2 opposite effects are in balance

biological term for the germ layer that gives rise to the nervous system​

Answers

The three germ layers are the endoderm, the ectoderm, and the mesoderm. Cells in each germ layer differentiate into tissues and embryonic organs. The ectoderm gives rise to the nervous system and the epidermis, among other tissues. The mesoderm gives rise to the muscle cells and connective tissue in the body.

A scientist is studying metabolic rate in a Giant Hummingbird in Peru. The scientist assumes a captured individual has been feeding on nectar (glucose) recently, but in fact the individual has not fed in the last hour and is currently metabolizing fat (palmitic acid). 3. Calculate the measurement error the scientist would introduce based on their faulty assumption if the scientist were measuring CO2 production. Will the scientist over- or underestimate metabolic rate

Answers

Answer:

Yes.

Explanation:

Yes, the scientist underestimate the metabolic rate of Giant Hummingbird. The scientist experience the measurement error due to non-feeding of Giant Hummingbird that leads to faulty assumption when the scientist were measuring CO2 production because the Giant Hummingbird breakdown the fats of the body for the release of energy instead of glucose. There is difference in the production of carbondioxide rate due to difference in the composition of fats and glucose.

2. Something an organism does in response to a change in its environment 2 poin
to ensure its survival. *
Structural adaptation
Functional apadtation
Behavioral adaptation
Mutual adpatation

Answers

Answer:

3. Behavioral adaptation

Explanation:

The environment is what helps everything live, which means that its behavior changes according to it's surroundings, such as a bear hibernating in the winter, that is its behavior because it is cold, and food is very hard to find, unlike in the summer and spring where food is everywhere, so the only choice the bear has is to collect as much food as it can before winter comes in.

Answer of the question

Answers

I can’t really see the question

HELP PLSSS !!
Based on this data, what can be concluded about the impact
seasonal changes have on these organisms around the Barents Sea?

A. The availability of solar energy limits photosynthetic productivity in winter months

B. Seasonal Changes have no impact on these organisms

C. During winter months the Diatom and zooplankton population completely die off due
to the lack of sunlight.

D. Due to the availability of solar energy, Diatom mass peaks in July.

Answers

Answer:

D. Due to the availability of solar energy, Diatom mass peaks in July.

Explanation:

Diatom are the photosynthetic algae which prepare food for themselves from the solar radiation just like plants. These diatoms produce more biomass or vegetation in the summer season mainly in July because availability of more sunlight in the Barents sea region while on the other hand, less biomass in the winter season due to low temperature and solar radiation which also effects the population of zooplankton organisms. So we can conclude that seasonal changes have a great impact on the organisms living around the Barents Sea.

Answer:

The availability of solar energy limits photosynthetic productivity in winter months

Explanation:

Trust me

Your friend runs out of gas and you have to help push his car. Discuss the sequence of bones and joints that convey the forces passing from your hand, through your upper limb and your pectoral girdle, and to your axial skeleton.?

Answers

Answer: The sequence of bones and joints that convey the forces include: From metacarpal bones --> carpal bones --> midcarpal and radiocarpal joints --> radius and ulna bones --> elbow joint --> humerus --> glenohumeral joint --> scapula --> acromioclavicular joint --> clavicle --> sternoclavicular joint --> sternum.

Note: the sign (-->) represents "into the".

Explanation:

The skeletal system is made up of bones of the skeleton, their joints and the skeletal muscles which acts together to bring about different movements in the body. The skeleton of a vertebrate had the following basic plan:

--> The axial skeleton: this forms the main central axis. This is made up of the skull,vertebral column, breastbone (sternum), and ribs.

--> The appendicular skeleton: this consists of parts that articulates with the axial skeleton. This is made up of the forelimbs, hindlimbs, pelvic and pectoral girdles.

From the question given, in an attempt to help push the friend's car, the sequence of bones and joints that convey the forces will pass from METACARPAL BONES of your hand into the CARPAL BONES at the base of your hand. Forces will then pass through the MIDCARPAL and RADIOCARPAL JOINTS into the RADIUS and ULNA bones of the forearm. These will pass the force through the ELBOW JOINT into the HUMERUS of the arm, and then through the GLENOHUMERAL JOINT into the SCAPULA. The force will travel through the ACROMIOCLAVICULAR JOINT into the CLAVICLE, and then through the STERNOCLAVICULAR joint into the STERNUM, which is part of the axial skeleton.

As one pushes against the car, the forces will pass in a sequential manner from the bones of the hand to the bones that are part of the axial skeleton.  

• Forces will pass from the metacarpal bones of the hand into the carpal bones at the base of the hand, when one pushes against the car.  

• After that the forces will then mediate via the radiocarpal and midcarpal joints into the ulna and the radius bones of the forearm.  

• Then the force will move via the arm's humerus, and then via the glenohumeral joint into the scapula.  

• The force then will mediate via the acromioclavicular joint into the clavicle, and then via the sternoclavicular joint into the sternum, that is, the part of the axial skeleton.  

Thus, in the given case, force gets mediated through the bones of the hand and towards the bones of the axial skeleton in a sequential manner.

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Sickle cell anemia is a genetic condition that occurs because of a single point mutation in the DNA gene for hemoglobin. How is this mutation expressed in humans?
A.) The protein coded by the DNA has a different amino acid sequence
B.) The chromosome caring this gene changes shape during cell reproduction
C.) The hormones in the bladder change by increase differences in genes
D.) The carbohydrate code by the DNA has a different structure

Answers

Answer:

B.) The chromosome carrying this gene changes shape during cell reproduction

Explanation:

According to this question, Sickle cell anemia is a genetic condition that occurs when the HBB gene that codes for haemoglobin protein undergoes a point mutation. Mutation alters the genetic sequence of a gene.

This mutation expresses itself when the chromosome 11 carrying the mutated gene changes shape during cell reproduction. Normal Red Blood Cell has a disc-shaped structure, however, this mutation causes a change in shape of the chromosome involved.

HELP BIOLOGY 50 POINTS !!!!!!
Biology fill in the blanks
below i attatched the blanks you have to fill
heres the words you have to use
-
lactase
repressor
transcribe
dairy products
e.coli
rna polymerase
operator
transcription
repressor
operator
lactose intolerant
protein
enzymes
bases
--
in the answer just put - the # and the answer for each blank
WILL GIVE BRAINLIEST

Answers

Answer:

1. lactose intolerant

2. lactase

3. dairy products

4. e.coli

5. enzymes

6. protein

7. repressor

8. operator

9. rna polymerase

10. transcribe

11. bases

12. repressor

13. operator

14. transcription

When the hilum of the kidney faces anteriorly, posteriorly, or laterally instead of medially, it is called

Answers

Answer:

Answer: skeletal system. When the hilum of the kidney faces anteriorly, posteriorly, or laterally instead of medially, it is called. a malrotated kidney.

Explanation:

Granite has only recently been exposed at a location on Earth’s surface. What will need to happen first in order for granite to become sedimentary rock?

Answers

Answer:

Granite has only recently been exposed at a location on Earth's surface. What will need to happen first in order for granite to become sedimentary rock? A thick layer of humus must form on top of the granite. The granite must be broken into smaller pieces by weathering processes.

Explanation: hope this helps dude

5. Which sentence would the author disagree wit

Answers

The author would disagree with C

Where are diploid cells found ?
A. only in reproductive organs
B. only in twin siblings
C. through out the body
D. only in the lungs

Answers

Answer:

c

Explanation:

diploid cells are cell that have 2 genetic alleles, one from your mom and one from dad, so all your cells are diploid, except haploid cells in the rep system.

the community interact with the air water soil sunlight and other non living things in its ​surrounding is what we call

Answers

Explanation:

non living things in their environment are called "matrix" its environment is what supports living and non living things...

The combination of fibers and ground substance in fluid connective tissue is known as
A) ground substance
B) fat
C) cytosol
D) plasma

Answers

A) ground substance

Which organism will have DNA most similar to the turtle?

Answers

Answer:

the answer is leopards!

Explanation:

I answered a similar question like this yesterday,

Hope it helps!!

The organism that will have DNA most similar to the turtle's will be other reptiles, particularly those in the same order as turtles, which is Testudines, which is present in Option A.

What is DNA sharing among ancestors?

Organisms that are closely related evolutionarily tend to have more similar DNA sequences than those that are more distantly related because they share a more recent common ancestor and have had less time to accumulate genetic differences. Turtles belong to the class Reptilia, which includes other reptiles like lizards, snakes, crocodiles, and birds. Within the reptile class, turtles are classified under the order Testudines, and other members of this order include tortoises and terrapins that share common characteristics with turtles.

Hence, the organism that will have DNA most similar to the turtle's will be other reptiles, particularly those in the same order as the turtles present in Option A.

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question is incomplete, complete question is below

Which organism will have DNA most similar to the turtle?

A)reptiles

B)fish

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