Answer:
Objective To examine the potential for publication bias, data availability bias, and reviewer selection bias in recently published meta-analyses that use individual participant data and to investigate whether authors of such meta-analyses seemed aware of these issues. Design In a database of 383 meta-analyses of individual participant data that were published between 1991 and March 2009, we surveyed the 31 most recent meta-analyses of randomised trials that examined whether an intervention was effective. Identification of relevant articles and data extraction was undertaken by one author and checked by another. Results Only nine (29%) of the 31 meta-analyses included individual participant data from “grey literature” (such as unpublished studies) in their primary meta-analysis, and the potential for publication bias was discussed or investigated in just 10 (32%). Sixteen (52%) of the 31 meta-analyses did not obtain all the individual participant data requested, yet five of these (31%) did not mention this as a potential limitation, and only six (38%) examined how trials without individual participant data might affect the conclusions. In nine (29%) of the meta-analyses reviewer selection bias was a potential issue, as the identification of relevant trials was either not stated or based on a more selective, non-systematic approach. Investigation of four meta-analyses containing data from ≥10 trials revealed one with an asymmetric funnel plot consistent with publication bias, and the inclusion of studies without individual participant data revealed additional heterogeneity between trials. Conclusions Publication, availability, and selection biases are a potential concern for meta-analyses of individual participant data, but many reviewers neglect to examine or discuss them. These issues warn against uncritically viewing any meta-analysis that uses individual participant data as the most reliable. Reviewers should seek individual participant data from all studies identified by a systematic review; include, where possible, aggregate data from any studies lacking individual participant data to consider their potential impact; and investigate funnel plot asymmetry in line with recent guidelines
Answer:
Objective To examine the potential for publication bias, data availability bias, and reviewer selection bias in recently published meta-analyses that use individual participant data and to investigate whether authors of such meta-analyses seemed aware of these issues. Design In a database of 383 meta-analyses of individual participant data that were published between 1991 and March 2009, we surveyed the 31 most recent meta-analyses of randomised trials that examined whether an intervention was effective. Identification of relevant articles and data extraction was undertaken by one author and checked by another. Results Only nine (29%) of the 31 meta-analyses included individual participant data from “grey literature” (such as unpublished studies) in their primary meta-analysis, and the potential for publication bias was discussed or investigated in just 10 (32%). Sixteen (52%) of the 31 meta-analyses did not obtain all the individual participant data requested, yet five of these (31%) did not mention this as a potential limitation, and only six (38%) examined how trials without individual participant data might affect the conclusions. In nine (29%) of the meta-analyses reviewer selection bias was a potential issue, as the identification of relevant trials was either not stated or based on a more selective, non-systematic approach. Investigation of four meta-analyses containing data from ≥10 trials revealed one with an asymmetric funnel plot consistent with publication bias, and the inclusion of studies without individual participant data revealed additional heterogeneity between trials. Conclusions Publication, availability, and selection biases are a potential concern for meta-analyses of individual participant data, but many reviewers neglect to examine or discuss them. These issues warn against uncritically viewing any meta-analysis that uses individual participant data as the most reliable. Reviewers should seek individual participant data from all studies identified by a systematic review; include, where possible, aggregate data from any studies lacking individual participant data to consider their potential impact; and investigate funnel plot asymmetry in line with recent guidelines
Explanation:
Difference between necessary and Sufficient?
Answer:
Hey there!
Necessary means that it is needed. For example, food and water are necessary for the well-being of humans.
Sufficient means that it is enough. For example, If we eat three healthy meals and drink water every day, we have sufficient food and water for our well-being.
Let me know if this helps :)
write a letter to the editor of daily paper on political vigilantism
When in the Course of human events, it becomes necessary for one people to dissolve the political bands which have connected them with another, and to assume among the powers of the earth, the separate and equal station to which the Laws of Nature and of Nature's God entitle them, a decent respect to the opinions of mankind requires that they should declare the causes which impel them to the separation.
We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness.--That to secure these rights, Governments are instituted among Men, deriving their just powers from the consent of the governed, --That whenever any Form of Government becomes destructive of these ends, it is the Right of the People to alter or to abolish it, and to institute new Government, laying its foundation on such principles and organizing its powers in such form, as to them shall seem most likely to effect their Safety and Happiness. Prudence, indeed, will dictate that Governments long established should not be changed for light and transient causes; and accordingly all experience hath shewn, that mankind are more disposed to suffer, while evils are sufferable, than to right themselves by abolishing the forms to which they are accustomed. But when a long train of abuses and usurpations, pursuing invariably the same Object evinces a design to reduce them under absolute Despotism, it is their right, it is their duty, to throw off such Government, and to provide new Guards for their future security.--Such has been the patient sufferance of these Colonies; and such is now the necessity which constrains them to alter their former Systems of Government. The history of the present King of Great Britain is a history of repeated injuries and usurpations, all having in direct object the establishment of an absolute Tyranny over these States. To prove this, let Facts be submitted to a candid world.
He has refused his Assent to Laws, the most wholesome and necessary for the public good.
He has forbidden his Governors to pass Laws of immediate and pressing importance, unless suspended in their operation till his Assent should be obtained; and when so suspended, he has utterly neglected to attend to them.
He has refused to pass other Laws for the accommodation of large districts of people, unless those people would relinquish the right of Representation in the Legislature, a right inestimable to them and formidable to tyrants only.
He has called together legislative bodies at places unusual, uncomfortable, and distant from the depository of their public Records, for the sole purpose of fatiguing them into compliance with his measures.
He has dissolved Representative Houses repeatedly, for opposing with manly firmness his invasions on the rights of the people.
He has refused for a long time, after such dissolutions, to cause others to be elected; whereby the Legislative powers, incapable of Annihilation, have returned to the People at large for their exercise; the State remaining in the mean time exposed to all the dangers of invasion from without, and convulsions within.
He has endeavoured to prevent the population of these States; for that purpose obstructing the Laws for Naturalization of Foreigners; refusing to pass others to encourage their migrations hither, and raising the conditions of new Appropriations of Lands.
He has obstructed the Administration of Justice, by refusing his Assent to Laws for establishing Judiciary powers.
He has made Judges dependent on his Will alone, for the tenure of their offices, and the amount and payment of their salaries.
He has erected a multitude of New Offices, and sent hither swarms of Officers to harrass our people, and eat out their substance.
He has kept among us, in times of peace, Standing Armies without the Consent of our legislatures.
He has affected to render the Military independent of and superior to the Civil power.
He has combined with others to subject us to a jurisdiction foreign to our constitution, and unacknowledged by our laws; giving his Assent to their Acts of pretended Legislation:
For Quartering large bodies of armed troops among us:
Do Our Neighborhoods Define Who We Are?
Your posts in the discussion area should exhibit careful thought and logical reasoning and provide evidence for your position. Each post should be at least one well-developed paragraph (approximately 4-6 sentences or more, unless otherwise indicated). Use correct spelling, punctuation, and grammar. The discussions must be completed by the due dates specified on the assignment.
Answer:
No our neighbors don't define who we are.
Explanation:
Our neighbors don't define who we are because we define ourselves about who we are like how we pick what we like, or chose who we want to be friends with. Our neighbors can't define who we are only you can. Our neighborhood do shape us, they place us in categories of economic stability, education and opportunity. Our neighbors can help define us but cannot define who we are or what we are.
Something that brings about an action or consequence is a(n)
Answer:
Cause
Explanation:
The cause brings an action or consequence.
The effect is the action due to the consequence.
Hope this helps!
Answer:
cause
Explanation:
Plz help idk which one it is
gerund phrase, you were right:)
How can this be re written in my own words
Answer:
Explanation:
summarize this.
u need to put some important lines and cut the lines which are not important
Which acronym can help you remember the components of a body paragraph? A. QEC B. REDI C. HELP
According to my manager's report, it was I/me who made the most sales for the month of June. Which pronoun should be used? I or me?
Answer:
You should use I
Brainliest Plz
using the word "I" is proper grammer
Why does Frederick Douglass describe the whipping of his Aunt Hester? A. to express his guilt over getting her in trouble B. to show his own capacity for violence C. to demonstrate what happens when enslaved people try to escape D. to convey the horrible brutality of slavery
Answer:
D.to convey the horrible brutality of slavery
Explanation:
I took the test and choose that other answer and it was wrong, so so I came back to help anyone else that needed the correct answer please give me brainiest please give me brainlest
Frederick Douglass describes the whipping of his Aunt Hester D. to convey the horrible brutality of slavery
According to the given account by the former slave, Frederick Douglass, he describes one particular event where his aunt was whipped by their slave masters for a trifle offence.
This was done, ion order to highlight the brutality of slavery and why it is wrong.
Therefore, the correct answer is option D
Read more here:
https://brainly.com/question/14730035
Describe the conflict in the passage by completing the
sentence.
Ponyboy is experiencing an
conflict
between
When I stepped out into the bright sunlight from the
darkness of the movie house, I had only two things on my
mind: Paul Newman and a ride home. I was wishing I
looked like Paul Newman - he looks tough and I don't -
but I guess my own looks aren't so bad. I have light
brown, almost-red hair and greenish-gray eyes. I wish
they were more gray, because I hate most guys that have
green eyes, but I have to be content with what I have. My
hair is longer than a lot of boys wear theirs, squared off in
back and long at the front and sides, but I am a greaser
and most of my neighborhood rarely bothers to get a
haircut. Besides, I look better with long hair.
- The Outsiders,
S.E. Hinton
Answer:
internal, himself and looks
Explanation:
Answer:
Describe the conflict in the passage by completing
Explanation:
What molecules make up the basic structure of Nucleic Acids?
Answer:
Each nucleotide is made up of a nitrogen base, attached to a sugar, which is then attached to a phosphate group. The nitrogen base can be either adenine, guanine, cytosine, thymine, or uracil. (A,G,C,T,U)
for what did Gulliver and his friend set out? what were his friend doing there?
Answer:
His business begins to fail when his patron dies, so he decides to go to sea again and travels for six years. Although he has planned to return home at the end of this time, he decides to accept one last job on a ship called the Antelope.
the children_in da park
how long should your thesis statement be
I recommend a few sentences, and for word count, use about 30 to 40 words. However, you can always break the rules as there are none.
Good luck on your theseis :) !
Answer:
two
Explanation:
What are some things you can infer about Marlow? Explain how you came to your conclusions.
Answer:
Marlow is a heroic character with a strong sense of justice, in addition to being curious and encouraged to discover mysteries, besides he is a character with traits of authoritarianism who likes to impose himself as an authority.
Explanation:
Marlow is a character in Heart of Darkness. While reading this work, we can see that he is a heroic character with a strong sense of justice since he does not conform to oppressive concepts and guidelines linked to the society in which he lives. This shows that Marlow is able to establish his own thinking based on his own convictions. However, this sense of justice contradicts Marlow's authoritarian traits, as he is not ashamed of using force to establish himself as an authority that must be respected.
Marlow is a person moved by the mystery, because it is very curious that this justifies his obsession with Kurtz.
Do you think
indifference
is more sinful
than hate?
Why or why not?
Answer:
“The opposite of love is not hate, it’s indifference. The opposite of art is not ugliness, it’s indifference. The opposite of faith is not heresy, it’s indifference. And the opposite of life is not death, it’s indifference.”
Answer:
Not
Explanation: In my opinion Indifference is not as hurtful as hate. Everyone has their own differences and we all have flaws. But to hate someone just makes them feel bad.
Why is the inclusion of the story of Beowulf's
swimming match with Brecca important? How
does this story connect to Beowulf's battle with
Grendel? What are we learning about Beowulf's
character?
Answer:
1. Because it shows that Beowulf is not perfect, then there is a reason to doubt his ability to beat Grendel.
2. The swimming match makes people doubt that Beowulf will be able to defeat Grendel, since she failed to win a foolish competition.
3. We are learning that Beowulf was indeed a hero, but he had certain limitations, which allows us to also see him as a human being.
Explanation:
Beowulf and Brecca had a silly swimming competition, just to show who was the fastest and best swimmer. Beowulf lost the competition and arrived after Brecca.
This defeat left many people unsure of Beowulf's ability to defeat Grendel. That's because Grendel was a powerful monster, the battle with him would be something serious and impossible to be won by a man who failed to win a swimming competition that had no significance.
This defeat of Beowulf teaches us that despite all the heroism and strength that he possesses, he remains a human being and is liable to fail like anyone else.
What is the difference between count noun and concrete noun?
Answer:
Countable noun :
The things that we can count 1 by 1 .
Eg. Stone, pens etc
where as,
Concrete noun:
The noun that we can touch,see.
Eg. Dog, dust
How would shylock's attitude towards the merchant influence risk analysis?
Shylocks main hatred lies Antonio's lending money gratis and insulting Shylock in every way possible. Shylocks hatred towards Christian society, makes the Christians to stay away from shylock. it is noticed the the Jew imposed heavy interest on the lent money
Does anyone have any advice on how to write this essay? I don't even know where to start
Answer:
"I open the car door and call out to them 45 minutes before it's time to get on the road. I then sit back and watch the X Games/ WWE matches that are surely to unfold as my 7 children and the poor dog eventually make their way to the vehicle. "We'll look at this..." I point out to no one in particular. "They're only 30 seconds past the 45 minute headstart that I gave them." And we're off still later than was planned, of course."
Explanation:
This is just one of the many stories I've told my friends and family as it pertains to being a mother of 7. That's 6 boys and 1 girl. Time nor age make your children move on schedule. LoL
*Start with action or dialogue.
*Ask a question or set of questions.
*Describe the setting so readers can imagine it.
*Give background information that will interest readers.
*Introduce yourself to readers in a surprising way
I hope this helps. This was a state to state road trip my husband and I took with our squad.
At this point in the story, the author will introduce the characters, setting, and relevant background information. *
Answer:
C.Both Diane France and the Number Devil love solving problems, but they solve them differently.
The title of a news story is called a dateline. True False
Answer:
false
Explanation:
Based on its use in the passage, it can be
understood that the word resemble
belongs to which of the following word
families?
highlight text
A. beat, master, overcome
B. play, amuse, entertain
C. defend, protect, preserve
D. echo, match, mirror
E. Support, uphold, maintain
The word resemble belongs to option D: echo, match, mirror word families.
What do you mean by term Resemble?Resemble means have qualities or features, especially those of appearance, in common with (someone or something); look or seem like.
According to given passage, the most appropriate family word that is equal to the resemble include echo, match and mirror.
Therefore, correct option is D.
Learn more about Resemble, refer to the link:
https://brainly.com/question/24820745
#SPJ2
"I don't want to be th e next Bruce Lee; I want to be the first Jackie Chan." - Jackie Chan meaning
Meaning that he isnt trying to copy off of someone personality or persona, he just trying to be himself or be original
Answer: It means that he isnt trying to copy off of someone personality or persona, he just trying to be himself or be original.
Explanation:
HELP ME PLEASE Identify types of genres for these broad categories: [1] music; [2] movies; [3] literary fiction.
Answer:
1) pop, rock, country
2) horror, sci-fi, thriller
3) contemporary, realistic, experimental
hope this helps :)
Select the correct answer from each drop-down menu.
clue provides a sample or an instance of the unknown word.
Answer:
Clue provides an instance of the unknown word.
Explanation:
A clue is a word, phrase, or symbol that can help one to determine the meaning of something that is unknown or missing in a context. It is a hint or pointer. During investigations, especially of a missing person, the police rely on clues provided by the surrounding events and the words used by others around to figure out the solution so that they can reconstruct the sequence of events and so decipher the whereabout of the missing person, the meaning of the action, or the words and symbols used.
Answer:
Example
Explanation: i think :/
what is the noun in the sentence next month will be my birthday
Answer:
sooooooo what is month
Explanation:
a nouns a person place or thing
Vocabulary Question 1: Read the sentences below and write the correct form of the base word given in the brackets. 1.Please _____________________ (convert) your numbers to percentages. 2. The _________________ (select) for the competition took place yesterday. 3. We have to make a ____________________ (choose) between eating healthy food and junk food. 4. She ____________________ (research) the topic before she gave the presentation. 5. We are waiting for a ___________________ (respond) from the manager on today’s agenda.
Answer:
1. convert
2. selection
3. choice
4. researched
5. response.
Explanation:
1. Please _________ (convert) your numbers to percentages.
The blank above expects an action word (verb) since the sentence expresses a need to do something - a need to convert some numbers to percentages.
Now since the base word given in bracket is in its verbal form, it can be used directly. So to fill in the blank, we have;
[Please convert your numbers to percentages.]
2. The ________ (select) for the competition took place yesterday.
The blank expects a noun since it has been preceded by a definite article "The". But the base word given in bracket is in the verbal form, it needs to be converted into its noun form. Therefore, select becomes selection
So to fill in the blank, we have;
[The selection for the competition took place yesterday.]
3. We have to make a choice between eating healthy food and junk food.
The blank expects a noun since it has been preceded by an indefinite article "a". But the base word given in bracket is in the verbal form, it needs to be converted into its noun form. Therefore, choose becomes choice
To fill in the blank, we have;
[We have to make a choice between eating healthy food and junk food.]
4. She _______ (research) the topic before she gave the presentation.
The blank above expects an action word (verb) since the first part of the sentence follows the subject, verb, object rule. i.e "She" is the subject, the blank should be the verb and "the topic" is the object.
The base word given in bracket is in its verbal form and so could fill the blank. However, the second part of the sentence illustrates that the action happened in the past. Therefore, to follow one of the rules of tenses, the blank has to be filled with the simple past of the base word. i.e research becomes researched
To fill in the blank, we have;
[She researched the topic before she gave the presentation.]
5. We are waiting for a __________ (respond) from the manager on today's agenda.
The blank expects a noun since it has been preceded by an indefinite article "a". But the base word given in bracket is in the verbal form, it needs to be converted into its noun form. Therefore, respond becomes response
[We are waiting for a response from the manager on today's agenda.]
stephano and trinculo most likley refer to caliban as a monster because
Answer:
Stephano and Trinculo were referred to Caliban as a monster because he was a deformed man.
Explanation:
Caliban is an antagonist in the play by William Shakespeare entitled 'The Tempest.'
The author, in dramatis personae, described Caliban as a 'savage and deformed slave.' Caliban is a son of witch, Sycorax. Caliban is a deformed slave with a half body of a man and half of an animal.
By Prosperous's statement which states Caliban as disproportioned in manner as disproportioned in his shape signifies that Caliban is not just ugly in his appearance but also in his character.
So, when Stephano and Trinculo is refering to Caliban as a monster they are referring to his deformed body of half-man and half-animal.
Hurry help!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Answer:
I think it is the fourth one.