Which cancer has a correlation with poorer outcomes when HER2 is overexpressed? A. Gastric B. C. D. Endometrial Lung Bladder

Answers

Answer 1

The cancer that has a correlation with poorer outcomes when HER2 is overexpressed is Gastric cancer.

HER2, also known as human epidermal growth factor receptor 2, is a protein that has the potential to contribute to cancer cell growth if overproduced. HER2 is a protein that is encoded by the HER2/neu gene, which is located on chromosome 17q21. When the HER2 protein is overproduced, it can result in the development of several types of cancer.

Herceptin, a breast cancer medication, is used to treat tumors that overproduce HER2 protein. HER2 is overproduced in around 20% of breast cancer cases. When HER2 is overproduced in other forms of cancer, it can indicate a more serious diagnosis. In gastric cancer, overexpression of HER2 has been linked to a poorer prognosis, indicating that patients are more likely to have a more aggressive form of the disease with a poorer prognosis.

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Related Questions

A nurse manager in a long-term care facility is discussing evidence-based practice staff nurses. What activities should the nurse manager identify evidence-based practice?

Answers

Evidence-based practice (EBP) involves the incorporation of current research-based evidence into clinical decision making. Evidence-based practice in nursing refers to the practice of nursing that is supported by clinical research and knowledge-based on the best evidence available.

Nurses at all levels of the organization must contribute to the practice's improvement through the incorporation of EBP, which leads to better patient outcomes.

The following are some of the activities that a nurse manager can identify for evidence-based practice staff nurses are:

1. Conducting routine staff meetings that include information regarding new evidence-based practices that have been implemented in other care settings, and updating staff members on any changes to current protocols or policies.

2. Encouraging staff nurses to participate in professional development opportunities such as conferences, seminars, and continuing education courses.

3. Providing access to relevant research studies and articles through the organization's library or online database.

4. Promoting evidence-based practice by encouraging staff to participate in quality improvement initiatives and research projects that aim to evaluate and improve care.

5. Using feedback from patient satisfaction surveys, staff surveys, and other sources to identify areas of improvement and opportunities to implement new evidence-based practices.

6. Developing policies and procedures based on the best available evidence, with input from staff members who work directly with patients.

7. Encouraging staff to conduct their research studies or quality improvement projects to improve patient care and outcomes.

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A prician report to the nurse? cud sequenual compression device to a patient. Which of the following should the
technician report to the nurse?
A. Discoloration to the extremity
B. Palpable pulse in the extremity
C.
Extremity is warm to touch
D. Decrease in edema to the extremity

Answers

As per the given question, a prician report to the nurse about sequential compression device to a patient, the technician should report A. Discoloration to the extremity to the nurse.

Sequenual Compression Device (SCD) is a device that helps prevent blood clots in the legs of a patient. It is usually given to those who have undergone surgery or who are critically ill. The SCD machine pumps up and deflates the leg cuffs to prevent blood from accumulating and causing clots. 

The technician should report discoloration of the extremity to the nurse immediately because it can indicate a lack of blood flow to the area. When blood flow is impeded, oxygen and nutrients cannot reach the tissues, which can lead to tissue damage or even necrosis. Discoloration to the extremity may also indicate that the SCD device is too tight, which can also lead to further complications. Therefore, the technician must report the discoloration to the nurse without any delay.

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Clearly describe the cardiopulmonary definition of death.
Clearly describe the higher-brain definition of death.

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Cardiopulmonary Definition of Death: Cardiopulmonary definition of death means a person’s brain can function if oxygen is provided, which can last up to four minutes following a cardiac arrest.

After that, if the supply of oxygen is not restored, the brain begins to die. It means that the heart and breathing have stopped, and there is no blood flow throughout the body. This occurs as the heart stops pumping blood around the body, and the brain does not receive oxygen.

At this point, doctors may declare a person deceased after confirming no signs of circulation or breathing. The cessation of cardiac function, which can be either a systole or asystole, is known as the final diagnosis of death. Brain death can be diagnosed after a person's cardiopulmonary activity stops. Brainstem reflexes like gagging and corneal reflexes become absent within 2-3 minutes, making it impossible for the individual to survive.

Higher-Brain Definition of Death: The higher-brain definition of death is the point at which the individual’s brain's higher centers (cerebral cortex) stop working. The cessation of electrical activity in the cerebral cortex is a clear indication of death in the higher-brain definition of death. In this case, there is no possibility of spontaneous breathing, heart rate, or other autonomic reflexes.

The cessation of electrical activity in the brain's cortex is the definitive diagnosis of brain death, which implies the irreversibility of the individual's brain function. The cessation of the brain's electrical activity also implies that the person has no ability to feel anything. Therefore, doctors may declare a person dead according to the higher-brain definition if they have no higher brain functions. In most cases, death by this definition happens after a catastrophic head injury or other neurological problems.

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1. Name the 5 criteria denoting Metabolic Syndrome, including cut off criteria or ranges.
2. Demonstrating ______ of these is diagnostic for Metabolic Syndrome.
3. What disease states does Metabolic Syndrome put you at high risk for?
4. What is the key pathogenic determinant (cause) for Metabolic Syndrome?
5. Metabolic Syndrome is really a precursor for what disease?
6. What are triglycerides and what do they do?
7. Describe the significance of "apple" vs "pear shape" in Metabolic Syndrome.
8. Describe the significance of food quantity and quality in Metabolic Syndrome.
9. What is the Glycemic Index? Why is awareness of this of significance in Metabolic Syndrome?
10. Is Metabolic Syndrome reversible? If so, how is this achieved?

Answers

Metabolism is a process that the body needs to produce energy from incoming food. Metabolic disorders can occur when abnormal chemical reactions occur in the body related to these processes and this can cause many health problems.

Here are the complete response to the queries:

1. Name the 5 criteria denoting Metabolic Syndrome, including cut-off criteria or ranges. The 5 criteria denoting Metabolic Syndrome include the following:

High fasting glucose: 100 mg/dl or higher.

High triglycerides: 150 mg/dl or higher.

Low high-density lipoprotein (HDL) cholesterol: Men under 40 mg/dL, Women under 50 mg/dL.

High blood pressure: 130/85 mm Hg or higher.

A large waist circumference: Men 40 inches or more, Women 35 inches or more.

2. Demonstrating three or more of these is diagnostic for Metabolic Syndrome.

3. What disease states does Metabolic Syndrome put you at high risk for?

Metabolic Syndrome put you at high risk for various disease states including:

Type 2 diabetes.

Cardiovascular disease including heart attack and stroke.Fatty liver disease.

Some cancers including colon, breast and endometrial cancers.

Sleep apnea and other respiratory problems.

4. What is the key pathogenic determinant (cause) for Metabolic Syndrome?

The key pathogenic determinant (cause) for Metabolic Syndrome is insulin resistance which develops as a result of a combination of genetic and environmental factors.

5. Metabolic Syndrome is really a precursor for what disease?

Metabolic Syndrome is really a precursor for type 2 diabetes.

6. What are triglycerides and what do they do?

Triglycerides are a type of fat found in the blood. They store unused calories and provide your body with energy, but high levels of triglycerides can increase the risk of heart disease.

7. Describe the significance of "apple" vs "pear shape" in Metabolic Syndrome.

People with "apple-shaped" bodies (those who carry weight around their waist) are at a higher risk of developing Metabolic Syndrome and related conditions, compared to people with "pear-shaped" bodies (those who carry weight around their hips and thighs).

8. Describe the significance of food quantity and quality in Metabolic Syndrome.

In Metabolic Syndrome, the significance of food quantity and quality is that the right balance of healthy foods can help reduce the risk of developing the condition.

9. What is the Glycemic Index?

Why is awareness of this of significance in Metabolic Syndrome?

The Glycemic Index is a measure of how quickly a food increases blood sugar levels. Awareness of this is significant in Metabolic Syndrome because it helps people choose foods that are less likely to spike blood sugar levels.

10. Is Metabolic Syndrome reversible? If so, how is this achieved?

Yes, Metabolic Syndrome is reversible. This can be achieved through lifestyle changes such as losing weight, exercising regularly, eating a healthy diet, quitting smoking, and managing stress levels.

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Mr. Johnny Wolf, a 40-year-old Native American male was admitted into ICU after falling off a very high cliff. His injuries include a fractured pelvis. bilateral fractures of his lower extremities, and contusions to his head and face. He received orders for an IV 0.9% NaCl 100 cc/hr, Demerol 50 mg with Vistaril 50 mg for pain IM every 3 to 4 hours PRN, a Foley catheter, CT scans, lab orders, and bedrest. He is allergic to ASA and watermelon. (Learning Objectives 1, 2, 4, 9, 10) 1. Describe how the nurse would prevent a needle stick after giving Mr.Wolf his IM injection for pain. 2. Describe the Z-track or (zigzag) method of giving an IM injection 3. List the steps to inserting a peripheral IV. 4. Mr. Wolf is complaining of his IV site hurting. List the signs and symptoms of an IV infiltration 5. List the parts of the syringe that has to maintain sterilit

Answers

To prevent a needle stick after giving Mr. Wolf his IM injection for pain, the nurse can follow these steps:

After administering the injection, activate the safety feature of the syringe or needle device according to the manufacturer's instructions.

Place the used needle or syringe into a designated sharps container immediately after use, without recapping or manipulating the needle.

The Z-track or zigzag method of giving an IM injection is a technique used to prevent medication from leaking back into the subcutaneous tissue and causing skin irritation. Here are the steps involved:

Select an appropriate needle length and gauge for the injection site and medication being administered.

Cleanse the injection site with an alcohol swab and allow it to dry.

Using the non-dominant hand, stretch the skin laterally to the side, creating a taut surface.

With the dominant hand, insert the needle quickly and deeply into the muscle at a 90-degree angle.

Aspirate to check for blood return. If blood appears, withdraw the needle and discard it.

Inject the medication slowly and steadily.

Remove the needle and release the skin, allowing it to return to its original position. This creates a "zigzag" or "track" path for the medication.

The steps for inserting a peripheral IV are as follows:

Perform hand hygiene and gather all the necessary supplies.

Identify a suitable insertion site, usually on the forearm or hand, by assessing vein visibility and palpability.

Apply a tourniquet above the intended insertion site to enhance vein prominence.

Cleanse the site with an antiseptic solution using an aseptic technique, starting from the center and moving outward in a circular motion.

Using a sterile needle or catheter, enter the skin at a 15-30 degree angle, with the bevel facing upward.

Once a flashback of blood is observed in the catheter hub, advance the catheter into the vein while stabilizing the needle.

Remove the tourniquet and release the vein occlusion.

Secure the catheter in place with an appropriate dressing and securement device.

Flush the catheter with a saline solution to ensure patency.

Document the procedure, including the catheter size, insertion site, and patient's tolerance.

Signs and symptoms of an IV infiltration include:

Swelling or edema around the IV site.

Coolness or cool temperature of the surrounding skin.

Pain or discomfort at the IV site.

Pallor or blanching of the skin around the site.

Slowed or stopped infusion flow.

Leaking of fluid or blood at the site.

Impaired mobility or restricted range of motion in the affected limb.

The parts of the syringe that need to maintain sterility are:

The plunger: It should not come into contact with any non-sterile surfaces or be touched with ungloved hands.

The needle or tip of the syringe:

It should remain sterile until the time of injection and not come into contact with anything non-sterile.

The barrel of the syringe:

It should be kept clean and free from contamination, although it does not need to maintain strict sterility.

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An obese white female presents to her health care provider with complaints of right shoulder and scapula pain. The nurse suspects cholecystitis. What history finding would the nurse expect to learn from this patient?

Answers

When a nurse suspects a patient of having cholecystitis, he or she would expect to learn the following history findings from the patient:A nursing assessment is required to investigate the patient's pain.

To assess for cholecystitis, the nurse should pay close attention to the patient's symptoms and medical history, particularly those that might point to an inflamed gallbladder. Cholecystitis is characterized by discomfort in the upper right abdomen and/or pain that radiates to the right shoulder or scapula.

It could also cause nausea, vomiting, and fever. Biliary colic: Biliary colic is a severe, spasmodic pain that is typically caused by the gallbladder contracting to release bile into the small intestine. When the bile duct becomes blocked, bile can no longer pass freely into the small intestine, and pressure builds up in the gallbladder, causing biliary colic.

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The opening of right atrium into right ventricle is guarded by a. aortic semilunar valve b. mitral valve c. tricuspid valve d. bicuspid valve

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The opening of the right atrium into the right ventricle is guarded by the tricuspid valve.

The tricuspid valve is a one-way valve located between the right atrium and the right ventricle in the heart. It consists of three leaflets or cusps that open and close to regulate the flow of blood. When the right atrium contracts, the tricuspid valve opens, allowing blood to flow from the atrium into the ventricle. Once the ventricle is filled, the tricuspid valve closes to prevent backflow of blood into the atrium during ventricular contraction. This closure of the tricuspid valve ensures that blood flows in the correct direction, from the right atrium to the right ventricle, and prevents regurgitation or leakage of blood.

The other options listed are not correct for the specific location mentioned. The aortic semilunar valve is located between the left ventricle and the aorta, the mitral valve (also known as the bicuspid valve) is located between the left atrium and the left ventricle, and the bicuspid valve is another name for the mitral valve. Each of these valves has its own specific location and function within the heart's circulation.

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The nurse is aware that the production of aldosterone is regulated by which of the following glands? (A) Thyroid gland B. Adrenal gland C. Pancreas D. Thymus gland

Answers

The production of aldosterone is regulated by B. Adrenal gland.

The production of aldosterone, a hormone involved in the regulation of salt and water balance in the body, is primarily controlled by the adrenal gland.

Aldosterone: Aldosterone is a hormone produced by the adrenal glands. It plays a crucial role in regulating the body's electrolyte balance, particularly the levels of sodium and potassium.

Adrenal gland: The adrenal glands are located on top of the kidneys. They consist of two main parts: the adrenal cortex and the adrenal medulla. The adrenal cortex is responsible for producing aldosterone, among other hormones.

Regulation of aldosterone production: The production of aldosterone is regulated by a feedback mechanism involving the renin-angiotensin-aldosterone system (RAAS).

When blood pressure or sodium levels are low, the juxtaglomerular cells in the kidneys release renin. Renin then acts on angiotensinogen to produce angiotensin I, which is converted to angiotensin II. Angiotensin II stimulates the release of aldosterone from the adrenal cortex.

Function of aldosterone: Aldosterone acts on the kidneys to increase the reabsorption of sodium and the excretion of potassium, leading to increased water retention and an overall increase in blood volume and blood pressure.

In summary, the production of aldosterone, a hormone involved in the regulation of salt and water balance, is primarily regulated by the adrenal gland.

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What are the economies of scale associated with larger medical
groups?
What are some of the challenges that large medical groups will
face in the years ahead?
Why is the federal government focused on

Answers

To sum up, economies of scale in healthcare can lead to better quality care and lower costs, and the federal government is focused on promoting consolidation in the healthcare industry in order to achieve these benefits.

The term economies of scale refers to the advantages or cost savings that a company can gain as it grows and expands its operations. It is a concept that is particularly relevant to the healthcare industry. One of the main benefits of economies of scale in the healthcare industry is that larger medical institutions can provide better quality care at lower costs.Larger medical facilities often have access to better technology and medical equipment than smaller clinics, and this can result in better quality care.

Additionally, larger medical institutions can negotiate better prices with suppliers and vendors, which can result in significant cost savings. Another important benefit of economies of scale in healthcare is that larger institutions can pool their resources to conduct research and develop new treatments and technologies.The federal government is focused on promoting economies of scale in healthcare because it believes that this can lead to better quality care and lower costs.

The government has implemented several policies and programs aimed at encouraging consolidation in the healthcare industry. For example, it has provided funding for the development of accountable care organizations (ACOs), which are groups of healthcare providers that work together to coordinate care for patients and improve quality while reducing costs. Additionally, the government has implemented regulations that require hospitals and other healthcare providers to report quality measures and outcomes, which can help to improve overall quality of care.

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42 y/o M w/ a 15 yr hx of EtOH dependence relapsed to alcohol abuse 5 mos ago. Patient currently drinks 5-6 drinks 4-5 times/wk. Reports no EtOH withdrawal sx after abstaining for 1-2 days on occasion. He now wants medication to help him to abstain. No home medications/OTC/herbals. NKDA. Rainbow labs WNL.
• What of the following would you recommend? • A. Naltrexone 380 mg IM
• B. Naltrexone 50 mg PO qday
• B. Acamprosate 666 mg PO TID
• C. Disulfiram 250 mg PO qday

Answers

Based on the patient's history of alcohol dependence and recent relapse, the recommended medication to aid in abstaining from alcohol would be disulfiram 250 mg PO qday. Here option C is the correct answer.

Disulfiram is an aversion therapy medication that discourages alcohol consumption by causing unpleasant symptoms when alcohol is ingested. It inhibits the enzyme acetaldehyde dehydrogenase, leading to an accumulation of acetaldehyde, a toxic metabolite of alcohol.

This accumulation results in a range of unpleasant symptoms, including flushing, nausea, vomiting, palpitations, and headache. Disulfiram is most effective when the patient is motivated to abstain from alcohol and understands the consequences of consuming alcohol while taking the medication.

It creates a deterrent effect by associating the ingestion of alcohol with unpleasant physical symptoms. The daily dosing ensures continuous coverage and reinforcement of the aversion therapy. Therefore option C is the correct answer.

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Once a neurotransmitter binds to its receptor and activates it, there is generation of a. Chemicals b. Electricity

Answers

Once a neurotransmitter binds to its receptor and activates it, there is the generation of electricity.

When a neurotransmitter such as dopamine, norepinephrine, serotonin, or acetylcholine attaches to a receptor, it may activate a signal transduction pathway, causing an electrical impulse to be generated, which is then conveyed down the axon of the neuron as an action potential to the presynaptic terminal. Neurotransmitters work by altering the permeability of a neuron's membrane to ions, allowing specific types of ions to enter or leave the cell.

This change in ion permeability is what results in the electrical activity that enables neurons to communicate with one another. The electrical signal is generated in the neuron's dendrites and cell body, where incoming information is processed and integrated, and then travels along the axon to the synapse. Once it reaches the synapse, the electrical signal is transformed back into a chemical signal via the release of neurotransmitters, which then activate receptors on the postsynaptic neuron.

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Safranin and methylene blue are both examples of basic dyes. Basic dyes are cationic (positively charged) and react with negatively charged material such as the cytoplasm and cell membrane. For the Gram stain, could methylene-blue be substituted for safranin? If so, why do you think safranin is used instead of methylene blue?
The acid-fast stain is another important differential stain used on some groups of bacteria. The primary stain is carbol fuchsin (deep pink; fuschia color), followed by an acid-alcohol decolorizer, and finally methylene blue (light blue color) counterstain. Acid-fast bacteria, such as Mycobacterium tuberculosis, retain the primary dye, whereas it is "washed" out of non-acid fast bacteria such as Escherichia coli. What colors would distinguish these two bacteria by this stain?
Mycobacterium tuberculosis
Escherichia coli

Answers

Methylene blue could be substituted for safranin in the Gram stain, as both are basic dyes that react with negatively charged material. However, safranin is commonly used instead of methylene blue in the Gram stain because it provides a better contrast with the crystal violet stain, making it easier to differentiate between Gram-positive and Gram-negative bacteria.

Both methylene blue and safranin are basic dyes used in staining techniques. In the Gram stain, these dyes can be used interchangeably as counterstains. However, safranin is commonly preferred over methylene blue in the Gram stain because it provides a clearer contrast with the crystal violet stain used as the primary stain.

Safranin stains Gram-negative bacteria a contrasting red color, allowing for easier differentiation between the Gram-positive (purple) and Gram-negative (red) bacteria. Methylene blue, although it can be used as a counterstain, may not provide the same level of clarity in distinguishing the two groups.

In the acid-fast stain, carbol fuchsin is the primary stain that imparts a deep pink or fuchsia color to acid-fast bacteria like Mycobacterium tuberculosis. Acid-fast bacteria have a unique cell wall composition that allows them to retain the primary dye even when treated with the acid-alcohol decolorizer.

Non-acid fast bacteria, such as Escherichia coli, do not retain the primary dye and are subsequently decolorized. To visualize the non-acid fast bacteria, they are counterstained with methylene blue, which gives them a light blue color. By observing the staining colors, the acid-fast bacteria can be distinguished from the non-acid fast bacteria in the sample.

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Which of the following hormones helps to prepare the breasts for lactation? Thrombopoietin Human chorionic gonadotropin Human placental lactogeni ANP

Answers

The hormone that helps to prepare the breasts for lactation is the human placental lactogen (hPL).

Lactation refers to the process of producing milk from the mammary glands and then expressing that milk through the nipples.

In humans, lactation is commonly associated with nursing babies.

Human Placental Lactogen is a hormone that is produced in the placenta during pregnancy.

It stimulates the growth of milk-secreting tissue in the breast and helps to prepare the breasts for lactation by increasing their size and sensitivity.

It also plays a role in regulating the mother's metabolism during pregnancy by increasing her insulin resistance and promoting the use of fatty acids for energy production.

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"Given drug: propranolol and sumatriptan
What are some pharmacological patient education/recommendations
for Migraine headache? Please be detail in small
paragraph

Answers

When providing pharmacological patient education and recommendations for migraine headaches, propranolol and sumatriptan, are two commonly used medications for migraine management.

For propranolol, a beta-blocker, patients should be advised to take it as prescribed by their healthcare provider. It is important to emphasize that propranolol is a preventive medication and should be taken regularly, even during headache-free periods, to achieve its maximum benefit. Patients should be informed about potential side effects such as fatigue, dizziness, or gastrointestinal disturbances. They should be advised not to abruptly stop taking propranolol without medical supervision due to the risk of rebound symptoms. As for sumatriptan, a triptan medication, patients should be instructed to take it at the onset of a migraine attack, as early treatment provides the best results. They should be aware that it is most effective when taken before the headache becomes severe. Patients should understand the recommended dosage and be cautious not to exceed the maximum daily dose. It is important to discuss possible side effects such as dizziness, flushing, or chest tightness, and advise patients to contact their healthcare provider if these occur or worsen.

In both cases, patients should be encouraged to keep a headache diary to track the frequency, duration, and intensity of their migraines, which can provide valuable information for their healthcare provider to assess treatment efficacy. It is crucial to emphasize the importance of open communication with their healthcare provider, reporting any concerns, changes in symptoms, or potential medication interactions. Ultimately, patient education should aim to empower individuals with knowledge about their medications and migraine management strategies, fostering a collaborative approach to their healthcare.

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The order is for 1000mL of R/L to run at 90mL per hour. The drop factor is 10gtt/mL. How many gtt/min should the IV run?

Answers

The IV should run at approximately 900 gtt/min to deliver 1000 mL of R/L over 11.11 hours at a flow rate of 90 mL/hour with a drop factor of 10 gtt/mL.

To calculate the number of drops per minute (gtt/min) for the intravenous (IV) infusion, we need to consider the volume, flow rate, and drop factor. Here's how you can determine the gtt/min:

Calculate the total time of the infusion:

To find the total time in hours, divide the total volume by the flow rate:

Total Time = Volume (mL) / Flow Rate (mL/hour)

In this case, the total time is:

Total Time = 1000 mL / 90 mL/hour = 11.11 hours

Convert the total time to minutes:

Multiply the total time by 60 to convert it to minutes:

Total Time (minutes) = Total Time (hours) * 60

Total Time (minutes) = 11.11 hours * 60 = 666.67 minutes

Calculate the total number of drops:

Multiply the total time (minutes) by the flow rate (mL/hour) and the drop factor (gtt/mL):

Total Drops = Total Time (minutes) * Flow Rate (mL/hour) * Drop Factor (gtt/mL)

Total Drops = 666.67 minutes * 90 mL/hour * 10 gtt/mL = 600,003 gtt

Calculate the gtt/min:

Divide the total number of drops by the total time (minutes):

gtt/min = Total Drops / Total Time (minutes)

gtt/min = 600,003 gtt / 666.67 minutes ≈ 900 gtt/min


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Calculation of Medications Used Intravenously cont. 3. A physician orders 3,000 mL lactated Ringer's solution to infuse over 16 hours. How many milliliters per hour should be administered?

Answers

The lactated Ringer's solution should be administered at a rate of approximately 187.5 milliliters per hour.

To calculate the milliliters per hour (mL/hr) for the lactated Ringer's solution, follow these steps:

Step 1: Determine the total volume of the solution.

Given that the physician ordered 3,000 mL of lactated Ringer's solution.

Step 2: Determine the infusion time.

Given that the infusion is to be completed over 16 hours.

Step 3: Calculate the milliliters per hour.

Divide the total volume by the infusion time:

Ml/hr = Total volume (mL) / Infusion time (hours)

Substituting the given values:

Ml/hr = 3,000 mL / 16 hours

Step 4: Perform the calculation.

Divide 3,000 mL by 16 hours:

Ml/hr = 3,000 mL / 16 hours

Ml/hr ≈ 187.5 mL/hr

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Complet ostomy care for your patient.Document the
intervention that you provided and the assessment that you
completed, including supplies used."

Answers

Ostomy care is a crucial aspect of nursing practice in any healthcare setting. As a nurse, it is essential to be proficient in providing ostomy care to patients with an ostomy.

An ostomy is a surgical procedure that involves the creation of an opening in the body to discharge urine, stool, or other bodily fluids from the body. Complete ostomy care involves a series of interventions that require a thorough assessment of the patient, documentation of the intervention provided, and the supplies used. Interventions for ostomy care involve assessing and cleaning the stoma, emptying the ostomy pouch, and monitoring the patient for any signs of complications.

Additionally, it is crucial to ensure that the patient is comfortable and educated about their ostomy and the care they require. Documentation is essential in providing safe and effective care to patients. As a nurse, you must ensure that your documentation is clear, concise, and accurate. Documentation should include a detailed assessment of the patient, interventions provided, and any complications observed. Supplies used should also be documented to ensure that the patient receives the correct supplies during subsequent ostomy care.

In conclusion, complete ostomy care requires a thorough assessment of the patient, effective interventions, and proper documentation.

As a nurse, it is essential to be proficient in providing ostomy care and ensure that your documentation is clear, concise, and accurate.

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which categories of medications under the fda’s pregnancy categories are considered to be within safe limits for use during pregnancy?

Answers

The FDA's pregnancy categories (A, B, C, D, and X) have been replaced by a more individualized method of evaluating the safety of prenatal drugs.

No particular class of drugs can be identified that can be used safely during pregnancy. Instead, health care professionals evaluate the advantages and disadvantages of each drug for pregnant patients based on currently available information.

Considerations include the drug's mechanism of action, previous research or data, and the severity of the disease being treated. Decision making regarding use of the drug during pregnancy requires consultation with a healthcare professional, which is absolutely essential for people who are pregnant. The health care professional will take into account the particular circumstances of the patient and advise on medicines that are believed to have an appropriate risk-benefit profile.

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Write a Science report (like a story) on the process of digestion.
Let us say for lunch, you have a cheeseburger.
Identify what are carbohydrates, proteins, fats and nucleic acids, dairy and vitamins etc are in your
cheeseburger.
Describe all the changes that take place once you put the food in your mouth, till all the wastes
are out of your system.
Name and describe all the organs through which the food passes and how the accessory organs
help in the process of digestion.
Make sure you use all the vocabulary terms related to the topic. Highlight those words.
Include the colored and labeled diagrams.
Must discuss the role of enzymes and which part of the main Macromolecules (Carbohydrate,
Protein, Fats, and Nucleic acid) are changed into simple nutrients.
Give the end products of each type of digestion. What happens after the absorption of all the
nutrients? What happens to particles, that cannot be digested or broken down?

Answers

The journey of digestion transforms the cheeseburger into simpler nutrients that our body can absorb and utilize. The organs of the digestive system, along with enzymes and other accessory organs, work in harmony to break down carbohydrates, proteins

Digestion is a complex process that breaks down the food we consume into simpler nutrients that our bodies can absorb and utilize. In this report, we will embark on a fascinating journey through the digestive system, focusing on the digestion of a cheeseburger. We will explore the various macromolecules present in the cheeseburger, the organs involved in digestion, the role of enzymes, and the fate of nutrients and undigested particles.

Cheeseburger Composition:

Our cheeseburger contains multiple components, including carbohydrates from the bun, proteins from the patty, fats from the cheese and meat, nucleic acids in the form of DNA within the cells, dairy from the cheese, and various vitamins and minerals

Digestion Process:

Oral Cavity:

Chewing (mastication) mechanically breaks down the food into smaller pieces, increasing its surface area.

Saliva, secreted by the salivary glands, contains amylase enzymes that begin the digestion of carbohydrates by breaking them into simpler sugars.

Pharynx and Esophagus:

The tongue and throat muscles help in swallowing, pushing the food into the pharynx and then the esophagus.

Peristalsis, rhythmic muscular contractions, propels the food down the esophagus.

Stomach:

The stomach secretes gastric juices, including hydrochloric acid and pepsinogen, which together form gastric acid and start protein digestion.

Churning motions of the stomach mix the food with gastric juices, forming a semi-liquid mixture called chyme.

Small Intestine:

The small intestine is the primary site of digestion and absorption.

The liver produces bile, stored in the gallbladder, which helps in the emulsification and breakdown of fats.

The pancreas secretes pancreatic enzymes (amylase, lipase, proteases) that further break down carbohydrates, fats, and proteins.

Villi and microvilli in the small intestine increase the surface area for nutrient absorption.

Large Intestine:

Water absorption occurs in the large intestine, leading to the formation of feces.

Beneficial bacteria in the colon aid in the fermentation of undigested carbohydrates and produce vitamins.

Rectum and Anus:

Feces are stored in the rectum until elimination through the anus.

Enzymatic Action and Nutrient Breakdown:

Carbohydrate digestion:

Amylase enzymes break down complex carbohydrates into simple sugars like glucose.

Protein digestion:

Proteases break proteins into amino acids.

Fat digestion:

Lipases break down fats into fatty acids and glycerol.

Nucleic acid digestion:

Nucleases break down nucleic acids into nucleotides.

End Products and Absorption:Carbohydrates: Simple sugars (glucose, fructose) are absorbed into the bloodstream.Proteins: Amino acids are absorbed into the bloodstream.Fats: Fatty acids and glycerol are absorbed into the lymphatic system.Nucleic acids: Nucleotides are broken down into their constituent parts and absorbed into the bloodstream.

Undigested Particles and Waste:

Fiber, cellulose, and other indigestible components pass through the digestive system mostly intact.

These indigestible particles contribute to bulk in feces and aid in maintaining healthy bowel movements.

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Discharge instructions for a patient that received mitomycin with a vinca alkaloid include monitoring for signs of A. blue urine. B jaundice. C alopecia. D breathlessness

Answers

Discharge instructions for a patient receiving mitomycin with a vinca alkaloid should include monitoring for blue urine, a potential side effect of mitomycin administration.

Discharge instructions for a patient who received mitomycin with a vinca alkaloid should include monitoring for signs of blue urine. Blue urine is an uncommon but potential side effect of mitomycin administration.

Mitomycin is a chemotherapy medication that can cause a rare condition called "blue diaper syndrome." It occurs due to the metabolism of mitomycin into a compound called mitomycin C, which can be excreted in the urine, leading to blue discoloration.

By monitoring for blue urine, healthcare providers can assess if the patient is experiencing this side effect. While blue urine itself is usually harmless, it is important to inform the patient about this potential occurrence to avoid any unnecessary concern or confusion.

It is worth noting that the other options mentioned, jaundice, alopecia, and breathlessness, are also possible side effects of chemotherapy but are not specifically associated with mitomycin and vinca alkaloid combination therapy. Therefore, monitoring for blue urine is the most relevant instruction to provide in this particular scenario.

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Based on the historical history of the low value of the role of people with intellectual disabilities in society, the ability of individuals and society In terms of both tolerance and the idea of "doing as much as possible" we are forced to take a "We'll do as much as possible" approach, explain the points to be noted in education and welfare.

Answers

In history, individuals with intellectual disabilities have been marginalized and their role in society has been undervalued. This has affected the way society views them and their potential for education and welfare. Therefore, when considering education and welfare for individuals with intellectual disabilities, there are several points that must be noted.

In education, it is important to provide inclusive and supportive learning environments for individuals with intellectual disabilities. This includes specialized teaching methods, individualized learning plans, and access to assistive technology and resources.

Additionally, it is important to address any barriers that may prevent individuals with intellectual disabilities from accessing education, such as physical barriers or societal attitudes and beliefs that may stigmatize or discriminate against them. In terms of welfare, it is important to provide adequate support and resources for individuals with intellectual disabilities to live fulfilling and independent lives.

This includes access to healthcare, housing, and employment opportunities. It is also important to address any social barriers that may prevent individuals with intellectual disabilities from fully participating in society, such as stigma, discrimination, or lack of social support. Finally, it is important to recognize the importance of promoting tolerance and understanding of individuals with intellectual disabilities within society.

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Connor Smith was admitted at 17 days of age with a high temperature. Connor also has an atrial septal heart defect and will be followed up with cardiology after discharge. A cause of the temperature was not found and the physician listed a final diagnosis of fever. provide the correct ICD 10 codes.

Answers

The correct ICD-10 codes for the scenario are as follows:

R50.9 for the fever Q21.1 for the atrial septal defect

Atrial septal defect is a congenital heart disease that affects the atrial septum. It is common in children but may not be diagnosed until adulthood. It is classified according to the location of the hole and can be either ostium primum, ostium secundum, or sinus venosus. The symptoms may not show up until later in life

Symptoms:

breathingpalpitationsfatigueleg swelling

A high temperature is represented by R50.9 in ICD-10. This code is used for unspecified fever. It is a medical condition that causes an increase in body temperature, above the normal range. It is a symptom of an underlying condition, rather than a disease on its own.

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NTR-218 Heart Disease Case Study Mr. R is a 52 year old accountant who is being seen for a routine physical exam. He has been in relatively good health, is not on any medications and has not seen a physician for the past 2 years. Mr. R is recently separated and has one daughter who is away at college. Mr. R's family history is positive for heart disease. His father had a fatal heart attack at age 48 and his older brother had a stroke at age 50. Mr. R attributes a 12 pound weight gain over the past 2 years (since his last physical) to a sedentary, stressed lifestyle. He works long hours and reports high stress levels both at home and on the job. He typically eats three meals per day, most in restaurants or take-out meals. Mr. R drinks two cups of coffee every morning and three alcoholic drinks (beer or wine) most evenings. Mr. R has been a smoker for 30 years, but has recently been successful at cutting back his smoking from one pack to one-half pack of cigarettes per day. On this visit, the following measurements are recorded: Height: 5'10" Weight: 212 lbs Waist: 44 inches Blood Pressure: 160/90 Fasting Glucose: 88 mg/dL Total Cholesterol: 245 mg/dL HDL: 38 mg/dL LDL: 160 mg/dL Mr. R reports the following 24 hour food intake: Breakfast (stops at Burger King) 1 Burger King biscuit with sausage, egg and cheese Coffee, 12 oz. with 2 Tbsp. Half & Half Mid-Morning (office) 1 jelly filled doughnut Coffee, 12 oz. with 2 Tbsp. Half & Half Lunch 2 slices Pepperoni Pizza Soda (Cola type), 12 oz. After Work 2 oz. cheddar cheese 5 Ritz crackers Beer, 12 oz. Dinner (Take out) Vegetable Egg Rolls (2) Moo shi pork, I cup White Rice, 1 cup Red wine, 2 glasses (5 oz. each) Vanilla Ice Cream, 1 cup 1. List ALL of the CHD risk factors that Mr. R has. For each modifiable risk factor, recommend a SPECIFIC diet or lifestyle change that could decrease his CHD risk. 2. Using the ACC/AHA heart attack Risk Assessment calculator (see on-line lecture B), calculate Mr. R's 10 year risk of having a heart attack. 3. What are the TLC recommendations for total fat, saturated fat and cholesterol intake? How do you think Mr. R's diet compares to those recommendations and explain your answer. 4. Suggest 5 tips to help Mr. R. change his diet so that it more closely aligns with the TLC recommendations. Your suggestions should be specific and actionable.

Answers

CHD risk factors for Mr. R: family history, sedentary lifestyle, high stress, unhealthy eating, excessive alcohol, smoking. Recommendations: regular exercise, stress management, heart-healthy diet, moderate alcohol, smoking cessation.

What are the CHD risk factors for Mr. R, and what specific diet or lifestyle changes can help reduce his risk?

List ALL of the CHD risk factors that Mr. R has. For each modifiable risk factor, recommend a SPECIFIC diet or lifestyle change that could decrease his CHD risk.

CHD Risk Factors:

  Family history of heart disease

  Sedentary lifestyle

  High stress levels

  Unhealthy eating habits (frequent restaurant and take-out meals)

  Excessive alcohol consumption

  Smoking

Recommendations for CHD Risk Reduction:

  Regular physical activity (e.g., brisk walking, aerobic exercises)

  Stress management techniques (e.g., meditation, deep breathing exercises)

  Adopting a heart-healthy diet (e.g., Mediterranean diet, DASH diet) rich in fruits, vegetables, whole grains, lean proteins, and healthy fats

  Limiting alcohol intake to moderate levels (e.g., one drink per day for women, two drinks per day for men)

  Smoking cessation or further reduction with the help of smoking cessation programs or therapies.

Using the ACC/AHA heart attack Risk Assessment calculator, calculate Mr. R's 10-year risk of having a heart attack.

To calculate Mr. R's 10-year risk of having a heart attack, the necessary data would include additional factors such as age, gender, race, blood pressure treatment status, diabetes status, and current medication use. Without this information, a specific calculation cannot be provided.

What are the TLC recommendations for total fat, saturated fat, and cholesterol intake? How do you think Mr. R's diet compares to those recommendations, and explain your answer.

TLC (Therapeutic Lifestyle Changes) recommendations:   Total fat intake: Less than 25-35% of total daily calories   Saturated fat intake: Less than 7% of total daily calories  Cholesterol intake: Less than 200 mg per day

Mr. R's diet likely exceeds the TLC recommendations. Based on the provided food intake, his breakfast, mid-morning snack, lunch, and dinner contain foods high in total fat, saturated fat, and cholesterol. The inclusion of fast food, doughnuts, pepperoni pizza, cheddar cheese, and ice cream contribute to his elevated intake of unhealthy fats and cholesterol.

Suggest 5 tips to help Mr. R. change his diet so that it more closely aligns with the TLC recommendations. Your suggestions should be specific and actionable.

Specific tips to align with TLC recommendations:

  Choose healthier breakfast options like whole-grain cereal with low-fat milk and fresh fruit.

  Replace sugary snacks with healthier alternatives like nuts or fresh vegetables with hummus.

Opt for homemade lunches with lean protein sources (e.g., grilled chicken) and plenty of vegetables.

  Reduce alcohol consumption to moderate levels or consider alcohol-free days.

Substitute high-fat desserts with healthier alternatives like fruit salads or Greek yogurt with berries.

By implementing these tips, Mr. R can gradually improve his diet by reducing total fat, saturated fat, and cholesterol intake, and move closer to the TLC recommendations for a heart-healthy diet.

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Calculate the total output in mL. 3 oz of urine 1.5 L of NG drainage 1500 mL of urine 4 oz JP drain

Answers

The total output in mL is 3206.91 mL.

To calculate the total output in mL, we need to add up the amounts of each fluid. First, we need to convert the given measurements into milliliters, so that we can add them up conveniently.

Here are the conversions we'll need to use:

1 L = 1000 mL 1 oz

= 29.5735 mL

So, the given measurements can be converted as follows:

3 oz urine = 3 × 29.5735 mL

= 88.62 mL1.5

L NG drainage = 1.5 × 1000 mL

= 1500 mL

1500 mL urine = 1500 mL

4 oz JP drain = 4 × 29.5735 mL

= 118.29 mL

Now, we can add up all the amounts of fluid to get the total output:

Total output = 88.62 mL + 1500 mL + 1500 mL + 118.29 mL

Total output = 3206.91 mL

Therefore, the total output in mL is 3206.91 mL.

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Your patient has hypothyroidism from a dysfunctional thyroid gland. Which of the following would you be least likely to see? a Tachycardia and exophthalmos
b. Elevated TSH, low T3, low T4 blood levels C. Constipation and decreased appetite D. Cold intolerance and lethargy

Answers

The condition in which an individual has an underactive thyroid gland is known as hypothyroidism.

Hypothyroidism is characterized by a reduction in the thyroid hormone levels in the blood. The symptoms of hypothyroidism develop slowly, often over several years, and are subtle. Individuals may not recognize the symptoms of hypothyroidism, or they may attribute them to other factors.

a. Tachycardia and exophthalmos.

There are several symptoms of hypothyroidism, which are as follows: Depression Lethargy, Fatigue Weight gain, Dry skin, Constipation Feeling cold, Joint pain, Sluggishness Reduced heart rate, Hypothyroidism can lead to a variety of health issues if left untreated.

To diagnose hypothyroidism, your healthcare provider may conduct a physical examination and blood tests. The treatment of hypothyroidism typically involves a daily dose of synthetic thyroid hormone. In order to monitor the condition, periodic blood tests may be required.

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Describe the role of the Eosinophils and mast cells in the pathogenesis of allergic asthma?
250 words
INCLUDE reputable reference

Answers

The role of the Eosinophils and mast cells in the pathogenesis of allergic asthma is by release various mediators such as histamine, leukotrienes, and chemokines which involved in bronchoconstriction, airway inflammation.

Eosinophils and mast cells play a crucial role in the pathogenesis of allergic asthma. Mast cells release various mediators, such as histamine, leukotrienes, and cytokines that are involved in bronchoconstriction, airway inflammation, and mucus hypersecretion. These mediators recruit and activate eosinophils, which are primarily responsible for the late-phase inflammatory response in asthma. Eosinophils release various inflammatory cytokines, chemokines, and cytotoxic proteins that induce epithelial damage, airway remodeling, and airway hyperreactivity.

Moreover, they also release reactive oxygen species, which contribute to the oxidative stress-induced inflammation seen in asthma. Eosinophils are recruited to the airways by IL-5, a cytokine produced by T helper 2 cells, and contribute to the sustained inflammation seen in asthma. In summary, both eosinophils and mast cells play a critical role in the pathogenesis of allergic asthma. Mast cells initiate the immediate-phase response, while eosinophils mediate the late-phase response. Hence, targeting these cells and their mediators may be an effective therapeutic strategy for the treatment of asthma.

References:
1. Global Initiative for Asthma (GINA). (2021). Global strategy for asthma management and prevention.
2. Lambrecht, B. N., & Hammad, H. (2015). The immunology of asthma. Nature immunology, 16(1), 45–56.

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A nurse is delegating feeding of a confused client who has graduated to feeding with assistance by an assistive personnel. A new AP is assisting the client with feeding .To ensure best practices and safety precautions, what responsibilities should the nurse comple with the delegation.

Answers

When delegating feeding of a confused client who has graduated to feeding with assistance by an assistive personnel, a nurse is expected to ensure best practices and safety precautions. To do this, the following are the responsibilities that the nurse should comply with: Assess the AP's competency level before delegating the task

The nurse must evaluate the AP's qualifications, abilities, and experience to ensure that they are qualified to assist in feeding a client who is disoriented. This could involve observing the AP feeding other clients and offering feedback or training if necessary. Alternatively, the nurse might ask the AP to complete a self-assessment and provide documentation of prior experience in feeding clients with similar needs or conditions. Make sure the AP understands the client's condition and the feeding plan

Before delegating the task, the nurse should provide the AP with specific information regarding the client's dietary requirements and preferences. In addition, the nurse should make sure the AP knows how to handle any feeding problems that may arise, such as difficulty swallowing, choking, or aspiration.

Document and evaluate the AP's performance: After delegating the feeding task to the AP, the nurse must monitor the AP's performance to ensure that the client's needs are being met. The nurse should document any observations or feedback related to the AP's performance and use this information to assess the AP's competency level and identify areas for improvement. The nurse should also regularly re-evaluate the AP's competency level to ensure that the AP remains qualified to assist in feeding the client.

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"Identify chronic disease states most commonly associated
with anemia (select all that apply)
A. Inflammatory disorders
B. Allergic responses
C. Chronic Obstructive Pulmonary Disease
D. Syndrome of Inappropriate

Answers

The given chronic disease states most commonly associated with anemia are Inflammatory disorders and Chronic Obstructive Pulmonary Disease (Options A & C)

What is Anemia?

Anemia is a medical condition characterized by a deficiency of red blood cells (RBCs) or hemoglobin in the blood. The condition may cause fatigue, shortness of breath, or increased heart rate, among other symptoms. Anemia is caused by a variety of factors, including blood loss, iron deficiency, or vitamin B12 and folate deficiencies.

The chronic disease most commonly associated with anemia is

A. Inflammatory disorders

C. Chronic Obstructive Pulmonary Disease

E. Chronic kidney disease

F. Rheumatoid arthritis

G. Gastrointestinal disorders

These conditions can contribute to the development of anemia through various mechanisms, such as reduced production of red blood cells, increased destruction of red blood cells, impaired iron absorption or utilization, and chronic inflammation affecting erythropoiesis.

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Explain the type of levers and exemplify in human
skeleton, draw figures.

Answers

The human skeleton demonstrates three types of levers: first-class levers, second-class levers, and third-class levers.

1. First-Class Levers: In a first-class lever, the fulcrum is positioned between the effort and the load. When force is applied to one end of the lever, the other end moves in the opposite direction. An example in the human body is the interaction between the head and the atlas vertebra, allowing for nodding movements.

2. Second-Class Levers: Second-class levers have the load located between the fulcrum and the effort. This arrangement provides a mechanical advantage, as a smaller force exerted over a greater distance can move a larger load over a shorter distance. The calf muscles exert force on the heel bone, resulting in lifting the body when standing on tiptoes.

3. Third-Class Levers: In a third-class lever, the effort is positioned between the fulcrum and the load. These levers offer a mechanical disadvantage, requiring a larger force to move a load a greater distance. An example is the action of the biceps brachii muscle on the forearm bones to flex the elbow joint.

Overall, the human skeleton showcases various types of levers, each playing a role in different movements and functions of the body. Understanding these lever types helps comprehend the mechanics and efficiency of human movement.

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Should enoxaparin be administered to patients post
parathyroidoctomy with tracheostomy?

Answers

Enoxaparin should not be administered to patients post-parathyroidectomy with a tracheostomy.

Enoxaparin is an anti-coagulant heparin with a low molecular weight, it is used to prevent blood clots from developing or getting bigger. It is usually administered subcutaneously and is often prescribed for people who have undergone major surgery like hip replacement to prevent DVT, as well as those who have a high risk of blood clots.

Enoxaparin must not be given to patients undergoing parathyroidectomy and tracheostomy as it significantly increases the risk of postoperative hematoma formation.

Hematoma is the collection of solid blood under the tissues and it causes the blood pressure to drop. if left untreated it can lead to coma or even death. therefore enoxaparin should not be administered to patients after parathyroidectomy surgery.

Enoxaparin sodium is prescribed after hip surgery:

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