What is the major product which results when (2R,3S)-2-chloro-3-phenylbutane is treated with sodium methoxide in methanol? A) (E)-2-phenyl-2-butene B) (2)-2-phenyl-2-butene C) (S)-3-phenyl-1-butene D) (R)-3-phenyl-1-butene E) (R)-2-methoxy-2-phenylbutane

Answers

Answer 1

The major product that results when (2R,3S)-2-chloro-3-phenylbutane is treated with sodium methoxide in methanol is (R)-3-phenyl-1-butene, which is option D.

When (2R,3S)-2-chloro-3-phenylbutane reacts with sodium methoxide (NaOMe) in methanol (MeOH), an elimination reaction known as the E2 reaction takes place. In this reaction, the chloride ion (Cl-) acts as a leaving group, and the base (methoxide ion, CH3O-) removes a proton from the adjacent carbon, resulting in the formation of a carbon-carbon double bond and the loss of a hydrogen chloride molecule.

The stereochemistry of the starting material is important in determining the stereochemistry of the product. In the given starting material, the chlorine atom and the phenyl group are on opposite sides of the molecule, indicating that they are in the trans configuration. As a result, the chlorine and the hydrogen atom that are eliminated in the reaction must be anti-periplanar, which means they must be in a staggered arrangement to allow for the most favorable overlap of the orbitals involved in the reaction.

The elimination occurs through a concerted mechanism, where the hydrogen and chlorine atoms are removed simultaneously, and the double bond is formed. The result is the formation of (R)-3-phenyl-1-butene as the major product. The (R) configuration refers to the absolute configuration of the chiral center that was present in the starting material.

Therefore, the correct answer is option D, (R)-3-phenyl-1-butene, as the major product obtained in the reaction between (2R,3S)-2-chloro-3-phenylbutane and sodium methoxide in methanol.

To learn more about elimination reaction here brainly.com/question/32943208

#SPJ11


Related Questions

why must the n-butyl acetate product be rigorously dried prior to ir analysis.

Answers

The n-butyl acetate product must be rigorously dried prior to IR analysis to ensure accurate and reliable results.

IR (Infrared) spectroscopy is a widely used technique to analyze the chemical composition and molecular structure of organic compounds. It relies on the interaction between infrared radiation and the functional groups present in the compound. However, water molecules can interfere with the IR analysis and produce misleading or distorted spectra.

Water molecules have strong absorption bands in the IR region, which can overlap with the absorption bands of the functional groups in the n-butyl acetate product. This overlapping can lead to incorrect interpretations of the IR spectra and hinder the identification and characterization of the compound.

To avoid this interference, the n-butyl acetate product needs to be dried rigorously before IR analysis. Drying typically involves removing any residual water from the sample. This can be done through techniques such as heating under vacuum or using desiccants.

By ensuring that the n-butyl acetate product is thoroughly dried, any water-related interference in the IR spectra can be minimized or eliminated. This allows for accurate identification and analysis of the functional groups present in the compound, leading to reliable results and meaningful interpretations.

Rigorous drying of the n-butyl acetate product prior to IR analysis is necessary to eliminate any interference caused by water molecules. By removing water, the IR spectra obtained will accurately represent the functional groups present in the compound, ensuring reliable and meaningful analysis.

To know more about n-butyl acetate, visit

https://brainly.com/question/31561741

#SPJ11

How much is 1 ug.min/ml in 1 mg.h/L?

Answers

ug/min/ml stands for micrgram per min per millilitre.ug/min/ml is generally used in the field of pharmacokinetics.To generally measure the mean concentration of any drug. These parametres are highly quantitative thus the chances of error is really high.

The units in which pharmacokinetic concepts are represented are a characteristic of the words' definitions and have an impact on the results of numerical calculations.

Consistency in symbol usage would minimise errors that might occur when interpreting values presented for different terms. The specific meaning of a phrase or concept as defined can frequently be clarified by carefully considering the units associated with it.To convert 1 ug/min/ml to mg/h L, the following is the calculation:1 ug/min/ml = 60 ug/h/L1 ug/min/ml = 0.00006 mg/h/L.Thus, 1 ug/min/ml is equal to 0.00006 mg/h/L.

Therefore, the answer is 0.00006.

Learn more about the mg/h/L here

https://brainly.com/question/15845518

#SPJ11

If an object weighs 3.4526 g and has a volume of 23.12 mL, what is its density?
Select one:
a. 0.15 g/mL
b. 0.149 g/mL
c. 1.50 x 10^-1 g/mL
d. 0.1493 g/mL

Answers

If an object weighs 3.4526 g and has a volume of 23.12 mL, the density of the object will be 0.1493 g/mL.

Density calculation

To calculate the density of an object, you need to divide its mass by its volume. In this case, the mass of the object is 3.4526 g and its volume is 23.12 mL.

Density = Mass / Volume

Density = 3.4526 g / 23.12 mL

Calculating the density:

Density ≈ 0.1493 g/mL

In other words, the density of the object is 0.1493 g/mL.

More on density can be found here: https://brainly.com/question/29775886

#SPJ4

Which element contains atoms with an average mass of 1.79 x 1022 grams? O Ag O Kr O Sc Fe O F

Answers

The element that contains atoms with an average mass of 1.79 x 10²² grams is Kr (Krypton).

The element that contains atoms with an average mass of 1.79 x 10²² grams is Kr (Krypton).

An element is a chemical substance in which all atoms have the same number of protons. There are around 118 known elements, which are identified by their atomic numbers, which represent the number of protons in their nuclei.

Krypton (Kr) is a chemical element with the atomic number 36. It is a noble gas with a symbol of Kr. Its boiling point is around minus 243 degrees Celsius. The density of krypton is 3.749 grams per cubic centimeter.

Krypton was found by Sir William Ramsay and Morris Travers in 1898, in the residue left over after liquid air had boiled away.

It is an odorless, tasteless, colorless, and non-toxic gas that can be obtained from liquefaction of air. Krypton is often utilized in flash bulbs used in high-speed photography and sometimes in fluorescent lights.

Therefore, the element that contains atoms with an average mass of 1.79 x 10²² grams is Kr (Krypton).

Hence, the correct answer is "Kr".

Learn more about average mass

brainly.com/question/28491910

#SPJ11

Other Questions
est the series below for convergence using the Ratio Test. n=0[infinity](2n+1)!(1) n3 2n+1The limit of the ratio test simplifies to lim n[infinity]f(n) where f(n)= The limit is: (enter oo for infinity if needed) Based on this, the series [infinity] financial statement frauds and potential of between information providers and users leads to a natural skepticism on the part of users. (enter only one word per blank.) 4. Give the three nuclear reactions currently considered for controlled thermonuclear fusion. Which has the largest cross section? Give the approximate energies released in the reactions. How would any resulting neutrons be used? 5. Estimate the temperature necessary in a fusion reactor to support the reaction 2H +2 H +3 He+n Calculate the eigenvalues of this matrix: [Note-you'll probably want to use a graphing calculator to estimate the roots of the polynomial which defines the eigenvalues. You can use the web version at xFunctions. If you select the "integral curves utility" from the main menu, will also be able to plot the integral curves of the associated diffential equations. ] A=[ 22120124] smaller eigenvalue = associated eigenvector =( larger eigenvalue = State the beginning reactants and the end products glycolysis, alcoholic fermentation, the citric acid cycle, and the electron transport chain. Describe where these processes take place in the cell and the conditions under which they operate (aerobic or anaerobic), glycolysis: alcoholic fermentation: citric acid cycle: electron transport chain what do you regard as the four most significant contributions of the mesopotamians to mathematics? justify your answer. the hepatic veins drain the blood from the liver and return it to the inferior vena cava. true false Determine whether the given differential equation is exact. If it is exact, solve it. (If it is not exact, enter NOT.)(y ln y exy) dx +1y+ x ln ydy = 0 Consider a radioactive sample. Determine the ratio of the number of nuclei decaying during the first half of its halflife to the number of nuclei decaying during the second half of its half-life. Describe the process of an action potential being propagated along a neuron using continuous propagation. Be specific. Be complete. An operational amplifier has to be designed for an on-chip audio band pass IGMF filter. Explain using appropriate mathematical derivations what the impact of reducing the input impedance (Zin), and reducing the open loop gain (A) of the opamp will have for the general opamps performance. What effect would any changes to (Zin) or (A) have on the design of an IGMF band pass filter? what should a sales associate do if a purchaser wishes to present a post dated check? predict the total packing cost for 25,000 orders, weighing 40,000 pounds, with 4,000 fragile items. round regression intercept to whole dollar and coefficients to two decimal places (nearest cent). enter the final answer rounded to the nearest dollar. Find the missing terms of each geometric sequence. (Hint: The geometric mean of the first and fifth terms is the third term. Some terms might be negative.) 2.5 , , , , 202.5, . . . . . . . Develop a minimum-multiplier realization of a length-7 Type 3 Linear Phase FIR Filter. read the case study for chapter 9 which can be found on page 172 of the textbook (shaw and carter, 2019). after reading the case study answer the following question: 1. what mistakes were made in the care of this patient? 2. identify how a patient-centered care perspective would have changed the experience of both nigel and joan? cansomone helpSolve for all values of \( y \) in simplest form. \[ |y-12|=16 \] credit-risk modelling: theoretical foundations, diagnostic tools, practical examples, and numerical recipes in python Pinto LC, Falcetta MR, Rados DV, Leitao CB, Gross JL. Glucagon-like peptide-1 receptor agonists and pancreatic cancer: a meta-analysis with trial sequential analysis. Scientific reports. 2019:9:1-6. which xxx would replace the missing statements in the following code to prepend a node in a doubly-linked list?