Three different small organic ligands can each bind to a protein but only one ligand can bind to the protein at a time. The KD for ligand 1 binding to the protein is 100 nM The KD for ligand 2 binding to the protein is 72 nM The KD for ligand 3 binding to the protein is 9 nM Which of the three ligands binds tightest to the protein?

Answers

Answer 1

Answer:

Explanation:

The binding affinity in ligand binding is measured using the equilibrium dissociation constant (KD).

The larger the dissociation constant value, the more weakly the target molecule and ligand are attracted to and bind to one another.

This, in this case study, the ligand that binds tightest to the protein is ligand 3 with a binding affinity of 9nM followed by Ligand 2 and then 1.


Related Questions

1.

behavior is inherited and



2. When a deer hears a sound in the forest, such a

then bolts through the bushes. This is an examp

3. Mating rituals or displays can be very complex

4. When animals fight and one wins and one subm

This means that one animal (the winn

behavior is used to intimidate other an

baring teeth or growling.

Answers

Answer:

Behavior is inherited in many animals which helps them to survive.

Explanation:

When animals fight with one another and one wins. This means that one animal (the winner) behavior is used to intimidate other. Two deer fight each other in order to show dominance over each other and to impress the female deer. The winner deer will be the leader and also mate with the females of the group. This is a type of behavior which is inherited in animals through genetics is called instincts.

B is representing a section of DNA that codes for a particular trait, which is a .

Answers

Answer:

The answer is "Gene"

Explanation:

To which domain does the animal kingdom belong? Bacteria Archaea Eukarya

Answers

Answer:

The correct answer is Eukarya.

Explanation:

The kingdom Animalia is one of four Kingdoms in the Domain Eukarya. This domain is further subdivided into the Kingdoms Protista, Plantae, Fungi, and Animalia.

Answer:

Eukarya is it

Explanation:

Describe an additional hypothetical situation that illustrates the "use it" portion of the use it or lose it principle. Be sure to describe the situation/behavior and explain why more bone is present under these circumstances. Also, describe an additional hypothetical situation that illustrates the "lose it" portion of the use it or lose it principle. Be sure to describe the situation/behavior and explain why less bone is present under these circumstances.

Answers

The first step of bone remodeling is the deposition of new bone cell to the destroyed portion. This is for maintenance of healthy bones

For a strong healthy body you have to take exercise regularly. This will replace unhealthy bone cell.

If you dont use your bone for support weight it will result of bone loss.. this is a situation of called lose it..

g What term refers to probes that will hybridize only with a complementary sequence and not with other sequences that may vary by as little as one nucleotide

Answers

Answer: Here are the options which are not given.

A) generation-specific probes

B) short, variable repeats

C) VNTRs

D) microsatellites

E) allele-specific oligonucleotides (ASOs)

E) allele-specific oligonucleotides (ASOs)

The correct Option Is E.

E) allele-specific oligonucleotides (ASOs)

Explanation:

Allele-specific oligonucleotides is a small synthetic DNA that proves which will hybridize with a only a complementary sequence of DNA and not with other sequence that may be different even with a nucleotides.

The DNA probe must be single stranded so that the desired Gene segment will be located.

The probe attach to the segment of DNA which has nucleotides complementary to its own.

Allele-specific oligonucleotide hybridization, or dot blotting, is a technique use to test known mutations.

During its Golden Age, China followed a policy of _____, believing their country to be the center of the world. Choose the best response. independence openness multiculturalism isolation

Answers

Answer:

multiculturalism

Explanation:

Te answere is: multiculturalism

What are the values of a, b, and c in the quadratic equation 0 = 5x – 4x2 – 2? a = 5, b = 4, c = 2 a = 5, b = –4, c = –2 a = –4, b = 5, c = –2 a = 4, b = –5, c = –2

Answers

Hey there! :)

Answer:

The 3rd choice. a = -4, b = 5, c = -2.

Explanation:

Rearrange the quadratic equation given into the form 0 = ax² + bx + c:

0 = 5x - 4x² - 2 --> 0 = -4x² + 5x - 2

The corresponding coefficients for the a, b and c values are:

a = -4

b = 5

c = -2.

The given quadratic equation must be first rearranged in the form ax2- bx-c. From this, we can find the values of a= -4, b= 5, and c= -2

How can a quadratic equation be defined?

Quadratics can be defined as a polynomial equation of a second degree, which implies that it comprises a minimum of one term that is squared. It is also called quadratic equations. The general form of the quadratic equation is ax² + bx + c = 0.

Quadratic equations are commonly used in situations where two things are multiplied together and they both depend on the same variable. For example, while working with the area, if both dimensions are represented in terms of the same variable, you use a quadratic equation.

Throwing a ball, shooting a cannon, diving from a platform, and hitting a golf ball are all examples of situations that can be modeled by quadratic functions.

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n which environment would mineral formation caused by high pressures and high temperatures most likely occur?

Answers

Answer:

when the flood or landslide flows theremnants of plants and animals are taken to the sea and ocean then due to high pressure and temperature they forms fossils in sedimentary rocks and due to the anaerobic condition under the fosdils gets decayed and it forms the layer of mineral. so we can say thatminerals are formed in anaerobic condition under sedimentary rocks.

In In what organ do sperm develop

Answers

Answer:

They develop in the TESTICLES.

Explanation:

TESTICLES are the two OVAL ORGANS that produce SPERM in MEN and other mammals, enclosed in SCROTUM behind the PENIS.

Which of the following are biomolecules? (check all that apply). *
carbohydrates
lipids
proteins
nucleic acis

Answers

Answer:

all of them

Explanation:

answer:E all of the above

Research has discovered that for some individuals one challenge to maintaining weight loss is that after losing weight lipoprotein lipase activity in their adipose tissue is .

Answers

Answer: Low.

Explanation:

Lipoprotein lipase or LPL is an enzyme that hydrolyzes triglycerides of low density lipoproteins found in food, and breaks them down to free fatty acids and glycerol. Then they are released into muscle and fat tissue. Without this enzyme, the fat particles would accumulate in the blood. Particularly, lipoprotein particles called chylomicron transport dietary lipids from the intestines to other locations in the body. So these complex, lipids and chylomicron, accumulate in blood.

Fats are a type of nutrient obtained from food. It is essential to eat some fats, although it is also harmful to eat too much. The fats in food give the body the energy it needs to work properly. And, during exercise, the body uses the calories from the carbohydrates that have recently been eaten, but after 20 minutes, exercise then depends on the calories from fat to continue.

So, if the activity of this enzyme is high, the fat in the food is broken down and the person would not gain weight (always considering that there is a correct diet and exercise) On the other hand, if the activity of the protein is low, large amounts of fat accumulate in the blood.

What best describes the behavior of nonconservative elements in seawater?

Answers

The given question is incomplete due to missing options, however, the options for the question as follows:

A. Nonconservative elements are reactive in seawater and have a long residence time.

B. Nonconservative elements are reactive in seawater and have a short residence time.

C. Nonconservative elements are non-reactive in seawater and have a short residence time.

D. Nonconservative elements are non-reactive in seawater and have a long residence time.

Answer:

The correct answer is option C.

Explanation:

Non conservative components are components that enter the ocean water and have little concentration in the sea and show spatial variations. These components have short home time that is short replacements time and they are non responsive.

Constituents, for example, phosphate, nitrate, and different supplements, and broke up oxygen, carbon dioxide, and so on are non-conservative on the grounds that their concentrations are later altered by chemical reactions in the ocean.

Thus, The correct answer is option C.

difference between plant and animal cyanide resistance respiration.

Answers

Answer:

The cyanide resistant respiration differs in plants as oxi­dation of reduced coenzyme continues even in the presence of cyanides.

Explanation:

The mitochondrial is the electrons through which the animals and plants perform the aerobic exercise and is blocked by the release of the cyanides that stops the activity and is known as cyanide sensitive respiration Plant mitochondria is different from the animal as they both have different oxidase system pathways. Cyanide resistant is responsible for the climacteric in fruits and for the generate heat in thermogenic tissues.

The mechanism by which proteins synthesized in the cytosol are imported into the mitochondrial matrix is different from the mechanism by which proteins enter the nucleus, yet the two mechanisms do share some features. Indicate whether each of the following statements applies to nuclear import, mitochondrial import, both, or neither. Sort each statement into the appropriate bin.
1. The polypeptide to be transported into the organelle has a specific short stretch of amino acids that targets the polypeptide to the organelle.
2. The imported protein enters the organelle through some sort of protein pore
3. The pore complex consists of more than two dozen proteins and is large enough to be readily seen with the electron microscope.
4. ATP hydrolysis is known to be required for the translocation process
5. The signal sequence is always at the olypeptide's N-terminus and is cut off by a peptidase within the organelle
6. The signal sequence is recognized
GTP hydrolysis is known to be required for the translocation process
7. There is strong evidence for the involvement of chaperone proteins polypeptide's N-terminus and isctand bound by a receptor protein inrequired for the translocation during translocation of the protein the organelle's outer membrane process.
Nuclear import Mitochondrial import Both Neither

Answers

Answer:

Nuclear import:

1. GTP hydrolysis is known to be required for the translocation process

2. The pore complex consists of more than two dozen proteins and is large enough to be readily seen through electron microscopy

Mitochondrial import:

1. ATP hydrolysis is known to be required for the translocation process

2. The signal sequence is always at the polypeptide's N-terminus and is cut off by a peptidase inside the organelle

3. There is strong evidence for the involvement of chaperones during the translocation process

4. The signal sequence is recognized and bound by a receptor protein in the organelles outer membrane

Both:

1. The polypeptide to be transferred into the organelle has a specific short stretch of amino acids that targets the polypeptide to the organelle

2. The imported protein enters the organelle through some sort of protein pore

Explanation:

At a continental-continental convergent boundary, _____. a, both continental plates are subducted b. one continental plate is subducted below the other c. folded mountains are formed d. fault-block mountains are formed

Answers

Answer:

I dont get it???

Explanation:

Answer:

I think both continental plates are subducted

which type of research study compares disease rates among population groups?

Answers

Answer:

Epidemiological

Explanation:

Epidemiology compares disease rates among population groups, and attempts to identify related conditions or behaviors.

Answer: Epidemiological studies

Choose the description of an event that does NOT occur during the cross bridge cycle. Group of answer choices Energized myosin heads bind troponin. ATP hydrolysis allows for cross bridge formation. ADP is released at the end of the power stroke. A new ATP binding causes cross bridges to release.

Answers

Answer: A myosin head binds to which molecule to form a cross bridge? ... Excitation-contraction coupling is a series of events that occur after the events of the ... performs a power stroke, then binds to ATP in order to detach and re-energize.

Explanation:

why did mendel use pea plants in his experiments A. they produced quickly B. they are all male C. they have no alleles D. they are haploid organisms

Answers

Answer:

They produce quickly

Explanation:

Mendel chose pea plants for his experiments because they are easy to raise, have many offspring per mating, can fertilize themselves and have varieties in genotype and phenotype that are easily observable. These characteristics make pea plants ideal in the study of genetics and heredity.

What are the differences between photosystem l and photosystem ll?

Answers

Answer:

in ps1, reaction centre is p700

in ps2, reaction centre is p680

Construct at least two possible hypotheses for the student’s experiment

Answers

Answer:

OFFICIAL SAMPLE ANSWER (Do not copy verbatim):

Hypothesis 1: The natural nutrients in compost will cause the tomato plants to grow at a faster rate than they grow when given artificial fertilizer.

Hypothesis 2: The artificial fertilizer is formulated specifically for tomato plants, so it will cause the plants to grow at a faster rate than they grow when given compost.

Explanation:

If questioned for situation below.....

"Many farmers and gardeners compost their plant and animal waste. The living material naturally decays in compost bins, forming a dirt-like substance that’s rich in nutrients. The next season, farmers use this substance as a natural fertilizer for their crops.

A biology student has grown tomato plants for several years. Until now, he used an artificial fertilizer formulated for tomato plants. This fertilizer caused his plants to grow faster and taller than they grew in unfertilized soil. The student wants to know whether using natural compost will cause his tomato plants to grow faster and taller than his artificial fertilizer.

"

1. compost pits and manure use, bio gas can be produced

2. using natural compost replenishes the soil fertility in the long run unlike the chemical fertilizers are two possible hypotheses for the student’s experiment

What are the basics of experiment ?

The basics of experiment is to test the hypothesis what we set previously and it is a foundation of the scientific method, types of experiments include controlled experiments, field experiments, and natural experiments.

The key steps taken in scientific method are observations, ask a question, making of hypothesis, design and conduct experiment, result, accept or reject or repeat the hypothesis from result.

The most important parameter taken in an experimental set up is variable which can be  dependent, independent and controlled variables where the independent variable is something which can not influenced by other factor.

A dependent variable can be changed by the influence of independent variable and Control variable can be  used to check bias of experiment.  

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is solar energy a renewable source of energy

Answers

Answer:

Solar energy is a renewable and  free source of energy

Explanation:

Solar Energy or Solar Power  is sustainable and totally inexhaustible

Answer:

Yes

Explanation:

Solar energy is a renewable source of energy. Solar panels take in the energy produced by the Sun and convert it into electricity.

Carolus Linnaeus Group of answer choices developed theories of natural selection. was a proponent of evolutionary change. established a binomial system of classification for plants and animals. was a supporter of Charles Darwin. opposed all notions of fixity of species.

Answers

Answer:

1- was a proponent of evolutionary change.  

2- established a binomial system of classification for plants and animals

Explanation:

Carolus Linnaeus was a Sweden naturalist that is considered to be the creator of the modern taxonomy. He created a dichotomic system to classify species, in which species are fixed entities without phenotypic modifications across time, this concept being contrary to Darwin's ideas. Linnaeus published his nomenclature botanical system in the book "Species Plantarum", which is nowadays a reference book for plant nomenclature.

Supposed you saw a small organism move across your book would you conclude that this organism was muticellular or unicellular?

Answers

Answer:

i would conclude it as a multicellular organism because i can see it as multicellular organism can only be seen and unicellular organism can only be seen in microscope.

hope u get that..

Answer:

multicellular

Explanation:

If I saw a small organism move across my book, I would conclude that the organism is multicellular. Multicellular organisms can be seen, unicellular organisms like bacteria cannot be seen through the naked eye.

what must happen before meiosis can begin A. the cell splits into four parts B. the chromosomes must replicate C. four haploid cells are produced D.DNA must duplicate four times

Answers

Answer:

B. the chromosomes must replicate

Answer: DNA replicates and forms retreads

Explanation:

How is the top layer of the ocean different than the deepest layer
A the top layer is colder and doesn’t receive sunlight
B the top layer receives sunlight and is warmer
C the top layer is warmer and doesn’t receive sunlight
D the top layer is colder and receives sunlight

Answers

Answer:

B the top layer receives sunlight and is warmer

Explanation:

Answer:

B. the top layer receives sunlight and is warmer.

What energy carrier molecules are produced by glycolysis

Answers

Answer:

"Glycolysis produces 2 ATP, 2 NADH, and 2 pyruvate molecules: Glycolysis, or the aerobic catabolic breakdown of glucose, produces energy in the form of ATP, NADH, and pyruvate, which itself enters the citric acid cycle to produce more energy"

Explanation:

Glycolysis | Boundless Biology - Lumen Learning

Which capillary would be least likely to allow substances to enter or exit the blood due to tight junctions that join the endothelial cells

Answers

Answer:

Those capillaries that have endothelial cells tightly attached have an increase in cell-to-cell junctions, such as desmosomal junctions that are poorly permeable to substances.

These capillaries generally function as conductors or collectors and not as permeabilizers like the pulmonary capillaries that are fenestrated and allow a high passage of substances and gases.

The capillaries are waterproof and prevent the passage of substances or fluids such as in the blood-brain barrier that is very selective

Explanation:

The blood-brain barrier is too selective since it is not favorable for the organism that many fluids, drugs, substances or chemical compounds enter the brain space.

This is the reason why the vessels are waterproof and why pharmacology was challenged to invent drugs that could cross this barrier since it was considered impossible.

An example is dopamine, which in parkynson's disease the levo group is added to dopamine, thus forming levodopamine as a product, this is the only way that the drug crosses the blood-brain barrier and can pass the impermeable barrier generated by capillaries with endothelial cells that are close to each other or closely linked

PLEASE HELP. DONT ANSWER IF YOU DONT KNOW. Name any three specifications that reduce carbon dioxide expenditure and promote biodiversity.

Answers

Answer:

A carbon footprint is the total greenhouse gas (GHG) emissions caused by an individual, event, organization, service, or product, expressed as carbon dioxide equivalent.[1] Greenhouse gases, including the carbon-containing gases carbon dioxide and methane, can be emitted through the burning of fossil fuels, land clearance and the production and consumption of food, manufactured goods, materials, wood, roads, buildings, transportation and other services.[2]

In most cases, the total carbon footprint cannot be calculated exactly because of inadequate knowledge of and data about the complex interactions between contributing processes, including the influence of natural processes that store or release carbon dioxide. For this reason, Wright, Kemp, and Williams proposed the following definition of a carbon footprint:

Specifications that reduce carbon dioxide expenditure and promote biodiversity are as follows:

1. Provide tree plantation through urban afforestation.

2. It has low concentration of carbon dioxide as plants absorb this gas and release oxygen

3. By promoting fruits and shade for the neighborhood.

What is Carbon Dioxide?

Carbon dioxide is defined as the chemical compound which is made up of molecules each containing a carbon atom bonded twice to two oxygen atoms and is found in the gaseous state at room temperature. In air, carbon dioxide is transparent to visible light but absorbs infrared radiation which acts as a greenhouse gas.

This is a minor component of the Earth's atmosphere at about 3 volumes in 10,000 employed by plants in the combustion of carbon-containing material, in fermentation, and in the respiration of animals and in the photosynthesis of carbohydrates.

Thus, specifications that reduce carbon dioxide expenditure and promote biodiversity are as follows:

1. Provide tree plantation through urban afforestation.

2. It has low concentration of carbon dioxide as plants absorb this gas and release oxygen

3. By promoting fruits and shade for the neighborhood.

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Like with living primates, we are able to definitively distinguish catarrhines from platyrrhines in the fossil record by what feature

Answers

Answer:

The structure of their noses.

Explanation:

Catarrhines are distinguished from platyrrhines by several traits but the main distinctive feature between them, is the structure of their noses. This forms the basis of their names.

Platyrrhines are characterized by laterally-placed, rounded nostrils or flat-nosed while catarrhines have narrow, downward-facing nostrils or hooked-nosed.

Another distinguishing feature include their dental formulation which is 2.1.2.3 in catarrhines and 2.1.3.3 in platyrrhines.

The skull structure of catarrhines have frontal bone which make contact with the sphenoid bone unlike the platyrrhines.

Generally, catarrhines are much bigger in size than platyrrhines.

why was an Archea considered as a prokaryote ​

Answers

Answer:

Archaea is prokaryotic because it doesn't have a nucleus, nor any membrane-bound organelles. The reason why Archaea is different from Bacteria is it is more prominent, most of them are extremophiles.

because they are composed of cell which doesn't have nucleus and other some cell organelles and also considered as incomplte cell.

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Which equation has the solutions x = 1 plus-or-minus StartRoot 5 EndRoot? x2 + 2x + 4 = 0 x2 2x + 4 = 0 x2 + 2x 4 = 0 x2 2x 4 = 0 Which of the following descriptions represent the transformation shown in the image? part 1 What happens to the soil fertility if some Rhizobium bacteria are added to the soil? Explain your answer MACBETH. Is this a dagger which I see before me,The handle toward my hand? Come, let me clutch thee.I have thee not, and yet I see thee still.Art thou not, fatal vision, sensibleTo feeling as to sight? or art thou butA dagger of the mind, a false creation,Proceeding from the heat-oppressed brain?-William Shakespeare, Macbeth, Act II, scene iWhat evidence leads you to believe that the dagger Macbeth sees is anillusion?O A. Come, let me clutch thee.O B. Is this a dagger which I see before meO c. I have thee not, and yet I see thee still.OD. The handle toward my hand? Im Nobody! Who are you? Are you Nobody too? Then theres a pair of us Dont tell! theyd advertise you know! How dreary to be Somebody! How public like a Frog To tell ones name the livelong June To an admiring Bog! Which technique does Dickinson use to make the ends of lines 1 and 2 sound similar? rhyme imagery controlling image alliteration can someone help me explain it which phrase from mark Antony's speech best shows that he is using ethos? Hurrry and answer plzzRead the sentenceAbert hopes they decide to reschedule the lecture for adifferent dayWhich sentence corrects the vague pronoun problem inthis sentence?He hopes they decide to reschedule it for a differentdayAlbert hopes the directors decide to reschedule thelecture for a different dayAbert hopes they decide to reschedule t for adifferent dayHe hopes the directors decide to reschedule thelecture for a different day state which triangle congruence postulate explains that the triangles are congruent en un dia de trabajo de 8 horas un obrero a hecho 10 cajas Epsilon Co. can produce a unit of product for the following costs:Direct material$8.40Direct labor24.40Overhead42.00Total costs per unit$74.80An outside supplier offers to provide Epsilon with all the units it needs at $66.20 per unit. If Epsilon buys from the supplier, the company will still incur 30% of its overhead. Epsilon should choose to:Buy since the relevant cost to make it is $74.80.Make since the relevant cost to make it is $62.20.Buy since the relevant cost to make it is $45.40.Make since the relevant cost to make it is $45.40.Buy since the relevant cost to make it is $62.20. What is the measure of x Which equation represents the statement below?Thirteen less than a number is forty-two.Select one:a.n 13 = 42b.42 13 =nc.13 n= 42d.13 42 = n is a man whom the local college students all think of as eccentric. Each day he stands on campus, smiling at people as they walk by, and he is known for his ever-present greeting of "Good luck!" In fact, the students at this campus have come to refer to him as "Good Luck Chuck." Nobody knows if he has a home or if he is destitute, but Charles never asks for anything. Which of the four criteria of mental illness might Charles satisfy The first time television played a role in electing a president was in 1928.Question 5 options:TrueFalse Find the gradient of the line segment between the points (-4,1) and (2,4). Give your answer in its simplest form. Two cities are identical in all respects except City A has an assessment ratio of 100% and City B (in another state) has an assessment ratio of 25%. Both cities need to raise $1,000,000 in property tax revenues. The statutory tax rates on property are 50 Points for whoever does it and shows their work. Maya has four glasses of milk. The temperature and the amount of milk in each glass are shown: Glass A: 20 grams of milk at 10 C Glass B: 50 grams of milk at 80 C Glass C: 20 grams of milk at 50 C Glass D: 50 grams of milk at 80 C Which statement is correct? 1. Place a checkmark next to each true statement about Mary Shelley:She was an actress before she became an author.She wrote Frankenstein as part of a ghost story-tellingcompetition between friends.None of her novels were successful during her lifetime.She lived a very sad, tragic life.She was the daughter of two political and social activists.Frankenstein was the only novel she wrote.Her writing reflects the political, social, and scientific revolutionsof her time. 14. Which of the following ray diagrams is correct for the mirror shown?