Medicine High School

the bone marrow is hypercellular, with 20 to 90% leukemic blasts at diagnosis or relapse. the blasts grow indiscriminately, but the cells have limited differentiation capability and are frozen in the earliest stage of development

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Answer 1

The statement "the bone marrow is hypercellular, with 20 to 90% leukemic blasts at diagnosis or relapse. the blasts grow indiscriminately, but the cells have limited differentiation capability and are frozen in the earliest stage of development" is true.

The bone marrow is hypercellular, meaning there is an excessive amount of cells present. In this case, the bone marrow contains 20 to 90% leukemic blasts at the time of diagnosis or relapse. Leukemic blasts are immature white blood cells that are characteristic of leukemia.

These leukemic blasts grow without regulation or control, leading to an overgrowth in the bone marrow. However, despite their rapid growth, these cells have limited differentiation capability. This means that they are unable to mature and develop into their intended specialized cell types. Instead, the leukemic blasts remain frozen or stuck in the earliest stage of development. This lack of differentiation contributes to the aggressive nature of leukemia, as the immature cells are unable to carry out their normal functions and disrupt the normal functioning of the bone marrow.

To summarize, in leukemia, the bone marrow becomes hypercellular with an abundance of leukemic blasts. These blasts grow uncontrollably and have limited differentiation capability, remaining frozen in their earliest developmental stage.

Learn more about bone marrow: https://brainly.com/question/30754540

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