The antibiotic rifampicin blocks transcription in many bacteria. In the presence of the antibiotic, adding sigma factor has no stimulating effect on RNA synthesis. A footprinting experiment on a rifamycin treated sample shows that the polymerase remains located at the promoter site in the presence of eNTPs and Mg2 ion. What step of transcription is rifamycin likely to block

Answers

Answer 1

Answer:

transcription initiation

Explanation:

Transcription is a process by which genetic information from DNA is used to synthesize an RNA molecule, usually, a messenger RNA (mRNA), which is subsequently utilized to synthesize a protein by a process called translation. Transcription in prokaryotes has three steps:

1-Initiation: the RNA polymerase is a multisubunit enzyme (holoenzyme) composed of two α, one β, one β’ and one ω and σ subunits (α2ββ’ωσ). This holoenzyme binds to the promoter region of the template DNA strand.

2-Elongation. The sigma σ factor of the holoenzyme is released and the complex and the core enzyme (α2 ββω) moves along the template strand, thereby producing an mRNA sequence

3-Termination. This step can be Rho-dependent, where a protein named "Rho" recognizes the termination site and stop transcription, and Rho-independent (transcription continues until the termination sequence is reached).

In consequence, Rifamycin is likely to block the initiation of transcription because the core RNA enzyme needs to bind the sigma factor (σ) for initiation of transcription in bacteria.


Related Questions

PLEASE ANSWER ASAP
Which of the following statements accurately describe a chromosome? Select all that apply.

a. Chromosomes contain one long DNA molecule that is tightly wound

b. Every chromosome has many genes as each gene is one segment of DNA

c. Every chromosome has one gene as an entire DNA makes up a gene

d. In any given organism, the gene(s) found on one chromosome can also be found on other chromosomes.

Answers

Answer:A

Explanation:

The statements that accurately describe a chromosome are:

a. Chromosomes contain one long DNA molecule that is tightly wound.

b. Every chromosome has many genes as each gene is one segment of DNA.

d. In any given organism, the gene(s) found on one chromosome can also be found on other chromosomes.

What is a chromosome?

A chromosome can be defined as a thread-like linear strand of deoxyribonucleic acid (DNA) that is typically found in the nucleus of each cell.

The characteristics of a chromosome.

In Genetics, some of the characteristics of a chromosome include the following:

Chromosomes is made up of a long deoxyribonucleic acid (DNA) molecule that is tightly wound.Every chromosome consist of many genes as each gene is a single segment of deoxyribonucleic acid (DNA).In any given organism, the gene(s) that is found on a chromosome can also be found on other chromosomes.

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The wings of butterflies and birds are ----------- structures because, although they are used for the same purpose (flight) they have very different structural compositions. Bird wings are made of bones and feathers while butterfly wings are made from chitin and are part of the insect’s exoskeleton.

A) homologous
B) analogous
C) vestigial

Answers

B. They are analogous structures because they share the same function, but not fully the same structural characteristics

Bird wings are made of bones and feathers while butterfly wings are made from chitin and are part of the insect’s exoskeleton.

B. They are analogous structures because they share the same function, but not fully the same structural characteristics.

What are examples of analogous?

Analogous Structures are:

Bird, Insect and Bat Wings. Duck and Platypus Bills.

Thus, option "B" is correct answer.

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Compare and contrast the outer core and the inner core. Mention 2 differences between the two cores.

Answers

Answer:

The outer core is colder than the inner core, and they are both inside the Earth. The inner core is the deepest layer of Earth's layers.

Explanation:

Please help me name each letter and match it to the definition. (Do not spam on my question either please)

Answers

Answer:

1. B. Medulla oblongata contains cardiac, respiratory, vasomotor and reflex centers.

2. A. Hypothalamus is the major regulator of ANS

3. D. Occipital lobe is the location of visual cortex.

4. F. Sensory areas are primary site responsible for perceiving cutaneous sensory sensations and proprioception.

5. E. Motor areas directs conscious motor movement

6. C. Cerebellum - coordinates movement by comparing intended movement with actual movement.

7. K. Corpus callosum allows communication between right & left cerebral hemispheres.

8. J. Frontal Lobe - Cognition, personality.

9. A. Hypothalamus - Contains hunger, thirst and thermoregulatory centers.

The TAS2R38 gene encodes a receptor protein that influences the ability to taste bitterness. The gene has two alleles: a dominant, wild-type allele that enables an individual (taster) to taste bitterness and a recessive, mutant allele that interferes with the ability of an individual (nontaster) to taste bitterness. In a sample of 2,400 people, 1,482 were found to have the dominant (taster) phenotype. Assuming that the population is in Hardy-Weinberg equilibrium, approximately how many individuals in the sample are expected to be heterozygous for TAS2R38

Answers

Answer:

The correct answer is - 1133.

Explanation:

According to H-W equilibrium;

p2 +2pq + q2 = 1 ........... eq.1   and

(p+q)2 = 1 ..............eq.2

Here q = frequency of the recessive allele,

and p = frequency of the dominant allele in the population

The genotype of p2 + 2pq shows the dominant(taster) phenotype.

The genotype of q2 shows the recessive(non-taster) phenotype.

q^2 = (2400 - 1482)/2400

= 0.3825  

= 0.618

using eq. 2 we get p= 1-q

=0.382

2pq = No. of heterozygotes/2400

No. of heterozygotes = 1133.1648

PLEASE HELP FAST!!!!

As humans continued to burn more and more oil and natural resources what has happened
to the world's carbon dioxide output?

Answers

Answer:

Global warming 100%  one of them.  And Air pollution.

Explanation:

Good luck

Which of the following are the main parts of the cardiovascular system?

A. thymus, lymph, lymph nodes, spleen, and tonsils

B. esophagus, stomach, small intestine, and large intestine

C. nose, pharynx, larynx, trachea, and lungs

D. heart, arteries, capillaries, and vines

Pls, help! I am currently taking a test with this question on it! I will mark brainliest if u are correct!

Answers

(D)

HEART,ARTERIES,CAPPILARIES,AND VINES

HOPE IT HELPS THANK YOU ☺

how does the soil environment support the earthworm in the students hand

Answers

The soil can determine how the earthworm will react, if there’s bad soil most likely there won’t be a lot of earthworms around

Which statement best explains the economic drawback of using geothermal energy over energy generated by fossil fuels?
More cost-effective over time
Higher installation costs than fossil fuel plants
More energy plant locations available
Less pollution than fossil fuel plants

Answers

Answer:

More cost-effective over time

Answer:

Could it be the higher installation costs than fossil fuel plants????

Explanation:

State and discuss two types of immunity.

Answers

Answer:

How Does the Immune System Work?

Innate immunity: Everyone is born with innate (or natural) immunity, a type of general protection. ...

Adaptive immunity: Adaptive (or active) immunity develops throughout our lives. ...

Passive immunity: Passive immunity is "borrowed" from another source and it lasts for a short time.

Name three benefits of keeping plants at home.

Answers

Answer:

Studies have shown that indoor plants...

Boost your mood, productivity, concentration and creativity.

Reduce your stress, fatigue, sore throats and colds.

Help clean indoor air by absorbing toxins, increasing humidity & producing oxygen.

Add life to a sterile space, give privacy and reduce noise levels.

What cell is this ?

Answers

Answer:

Animal cell

Explanation:

what do endocrine glands use as Messengers?

A. Blood
B. Hormones
C. Target Organs
D. Zygote

Answers

Answer:

b. hormones

Explanation:

"The endocrine system is made up of glands that make hormones. Hormones are the body's chemical messengers. They carry information and instructions from one set of cells to another"

Answer:

b have a good day

Explanation:

What is the correct equation for the breakdown of ozone? please answer quick

Answers

Answer:    This electricity converts the oxygen molecule to ozone. Our equation is as follows: 3O2 + energy = 2O3.

The correct equation for the breakdown of ozone can typically occur in a series of two steps known as the destruction of ozone. It is illustrated thus;

Cl + O3 ⇒ ClO + O2ClO + O ⇒ Cl + O2

The net reaction of the above process is the reaction of an oxygen atom with an ozone particle to form two molecules of oxygen.

The catalyst in this reaction is chlorine because it undergoes changes as the process continues while ozone is removed in the process. In the presence of sunlight, atomic oxygen is formed.

This entire process is referred to as the destruction of ozone.

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GIVING AWAY 18 POINTS PLEASE HELP ME ASAPPP!!!

Answers

Answer:a major ecosystem defined by distinctive geography and receiving uniform solar radiation and moisture

Explanation:

A marsupial mole has claws for burrowing, a keen sense of smell, and reduced vision in its eyes. The placental mole, a mammal on a
different branch of the mammalian evolutionary tree, has claws for burrowing, a keen sense of smell, and reduced vision in its eyes.
Which statement(s) describe the relationship between these two moles? Select ALL that apply.
A)
Convergent evolution occurred in these two mammalian species.
B)
These two species evolved under similar environmental pressures.
C)
These two species do not have a common ancestor, but evolved from
separate lineages.
D)
Identical mutations occurred within the two different lineages creating
identical phenotypes.
E)
These two species share a more recent common ancestor than they do with
other mammalian species.

Answers

Answer: a and b

Explanation:

i just took it

The relationship between these two mammalian species is that Convergent evolution occurred in these two mammalian species. That is option A.

What is Convergent evolution?

Convergent evolution is the type of evolution where distantly related organisms evolve similar traits to adapt to similar environmental conditions.

The marsupial mole and the placental mole are distant species with similar features.

Therefore, the relationship between these two mammalian species is that Convergent evolution occurred in these two mammalian species.

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3. In most cells,
directs the production of a
which then enters a ribosome. The
molecule of
ribosome produces the final product,
Retroviruses do the opposite. They use the enzyme reverse
transcriptase to use a template of
to produce

Answers

Answer:

In most cells, DNA directs the production of a molecule of mRNA which then enters a ribosome. The ribosome produces the final product, a protein. Retroviruses do the opposite. They use the enzyme reverse transcriptase to use a template of mRNA to produce DNA.

Explanation:

The central dogma of molecular biology describes how a cell uses its genetic information to synthesize a protein. The first step called 'transcription' consists of using an RNA polymerase enzyme and a fragment of DNA (i.e., gene) as a template to synthesize an RNA molecule, usually a messenger RNA (mRNA). Subsequently, the genetic code in the mRNA sequence is read by the ribosomes in order to produce a protein, a process known as 'translation'. Retroviruses are viruses that have the ability to integrate into the host genome by using a reverse transcriptase enzyme that allows reverse transcription of mRNA to complementary DNA, which then integrates into the host's genome.

The correct options in the blanks are DNA, mRNA, Protein, mRNA, and DNA respectively.

What is gene expression?

It is the process by which cells produce protein from DNA molecules. DNA produces RNA which contains codes to produce amino acids.

The mRNA enters the ribosome which produced protein using the codons of mRNA.

Retroviruses have special machinery to produce the DNA from mRNA.

Therefore, the correct options in the blanks are DNA, mRNA, Protein, mRNA, and DNA respectively.

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In which division phase is the nucleolus formed and spindle fibers broken down?
A) anaphase
B) prophase
C) metaphase
D)telophase

Answers

Answer:

Prophase

Explanation:

During prophase, the nuclear envelope and nucleolus are dissolved and the chromosomes condense. The centrioles and spindle fibers begin to form at opposite poles of the cell.

Answer:

telophase

Explanation:

Spindle fibers disperse as the chromosomes are separated and become housed within two new nuclei.

Taking two aspects of their relationship, explain how the marriage of the Prophet and Khadija set a good example for Muslim marriages today?

Answers

Answer:

Due to their behaviour towards each other.

Explanation:

The marriage of the Prophet and Khadija set a good example for Muslim marriages today because their strong relationship and respect towards each other is the key to their beautiful marriage life. In marriage life, both husband and wife has great contribution to their relationship. If both husband and wife respect each other and support in every situation of life so their relationship will be strong and they live a beautiful marriage life so we can say that the marriage life of Prophet (S.A.W) and Khadija is a good example for all Muslims.

The diagram below represents some stages in the life cycle of humans. The numbers in the diagram represent various processes in the cycle.




Identify the process(es) represented by 1 and 2. State how these processes (1 and 2) affect the amount of genetic information provided by a parent to its offspring.

Answers

Answer:

The diagram below represents some stages in the life cycle of humans. The numbers in the diagram represent various processes in the cycle.

1. "The processes reduce the amount of genetic information from each parent by half."

During sexual reproduction, a specialized cell division process called meiosis occurs. Meiosis involves two consecutive divisions, resulting in the production of four haploid cells (gametes) from a diploid cell.

2. "Each parent only contributes half of the genetic information that is contained in his or her own cells."

As mentioned earlier, meiosis results in the formation of haploid gametes. Each gamete contains only one set of chromosomes, which is half the number found in the parent's diploid cells.

During meiosis, homologous chromosomes pair up, and genetic recombination occurs between them, shuffling and exchanging genetic information.

3. "Each egg (or each sperm) will carry only half of the genetic information contained in the parent's body cells."

This statement reiterates that gametes (eggs or sperm) are haploid cells containing only one set of chromosomes. When a cell undergoes meiosis to produce gametes, it divides twice, resulting in four cells with half the genetic information of the parent's body cells.

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Why did the accepted scientific theory of the solar system change from a geocentric model with Earth in the center to a heliocentric model with the Sun in the center?

Question 2 options:

A: Because over time the Sun's position changed


B: Because over time the Earth's position changed


C: New evidence and observations changed our understanding of the solar system


D: New planets formed in between the Sun and Earth

Answers

I think it is A and C sorry if I’m wrong


Ecosystems can stay stable for hundreds of years, but loss of resources or addition of disease can quickly change the dynamics of said ecosystem.
True
OFalse

Answers

True ecosystems tend to depend on some sort of aid or resource and if it goes away so will that ecosystem

Where would you expect to find humans with the darkest skin color in the Northern Hemisphere (from 10°N to 60°N)?

Answers

Answer: Australia

Explanation:


The diagram below, best represents.

Answers

Answer:

B. An Ecosystem

Explanation:

A C and D do not fit the picture.

A directional flow of electric charge

Answers

Answer:

The direction of an electric current is by convention the direction in which a positive charge would move. Thus, the current in the external circuit is directed away from the positive terminal and toward the negative terminal of the battery. Electrons would actually move through the wires in the opposite direction.

Conventionally, a positive charge would go in the same direction as an electric current. As a result, the battery's positive terminal receives less current in the external circuit than its negative counterpart. Actually, electrons would go in the reverse direction across the cables.

What is electric current ?

A stream of charged particles, such as electrons or ions, traveling through an electrical conductor or a vacuum is known as an electric current. The net rate of electric charge flowing through a surface or into a control volume is how it is calculated.

The cell phone, trains, ships, refrigerator, and the motors in appliances like food processors all run on electricity. To be useful, electric energy must be converted into other forms of energy like heat, light, or mechanical.

Conventionally, a positive charge would go in the same direction as an electric current. As a result, the battery's positive terminal receives less current in the external circuit than its negative counterpart.

Thus, a positive charge would go in the same direction as an electric current.

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((I need the punnet square but not sure how to make it))​

Answers

Answer:

i don't know why but you probably don't want to go to the link... sorry

Answer:

Explanation:

Okay, so the female's eyes will be Xx because she carries it and I am not sure if the male is a carrier as well or not so if he is it will be Xx on the top and Xx on the side of the male is not then it will be XX and Xx and it does not matter which is on top which is on the bottom. If the male is a carrier then the outcomes will be XX, Xx, Xx, xx so they will have a 1:4 chance of getting white eyes if the male is NOT a carrier then it will be XX+Xx = XX, XX, Xx, Xx with no chances of having white eyes

What is the answer to that question

Answers

Answer:

D. Steps to use for doing the Heimlich maneuver

Explanation:

That's what the section is talking about.

Factors that control traits are called?

a. genes.
b. purebreds.
c. recessives.
d. parents

Answers

Answer:

A. Genes

Explanation:

Which of the following is true about pea
plants?

A. They produce a small number of offspring.

B. They produce asexually.

C. Their female parts can be artificially pollinated.

D. They don't have many contrasting characters.

Answers

The statement true about pea plant are as,

They produce a small number of offspring.Their female parts can be artificially pollinated.

What is artificial pollination?The pollination which is carried by human is called artificial pollination.It is used to pollinate plants when natural pollination is insufficient and undesirable.The artificial pollination consider as mechanical technique.There is no requirement of insect and weather.The example of plant in which artificial pollination can occur is kiwifruit.

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which type of bond forms between water molecules

Answers

Answer:

hydrogen bonds

Explanation:

Hydrogen bonds form between neighboring hydrogen and oxygen atoms of adjacent water molecules.Attraction between individual water molecules creates a bond known as a hydrogen bond.

Answer:

hydrogen bonds.

Explanation:

In the case of water, hydrogen bonds form between neighboring hydrogen and oxygen atoms of adjacent water molecules. The attraction between individual water molecules creates a bond known as a hydrogen bond.

Other Questions
Both the Maya and the Aztec had two ____________________, one for trackingreligion and one for farming. Home Inspirations. Hailey works for her father in a family-owned business called Home Inspirations, a bedding company that has been in operation since the 1800s. When her father retires, Hailey plans on taking over the business. Hailey is aware of many things about the company that she likes, and a few things that she does not. She has particularly noted that when the economy has low unemployment and high total income, sales are great. However, at any other time, sales are not so good.Currently, all of the bedding items are created in one place and everyone works on various tasks every day. Hailey is thinking about streamlining the production process so that individuals would be responsible for only one task. She believes that if production would increases, she could sell her products at a lower price and increase revenue. She knows that most bedding products available in the market are very similar in nature and satisfy the same need. However, if she were able to lower prices, this might give her company the competitive advantage that it needs. She would then be able to invest money in differentiating her products by providing unique features, building the brand name, and offering services such as free delivery. She is also considering selling her products on the Internet. Hailey knows that her father does not like change very much, but she feels these changes are important for the future of the company.Hailey feels that for productivity to improve, the company must practice: _________.a. Free enterprise,b. Work ethics,c. Specialization,d. Cultural diversity,e. Pure competition. HELP ME NOW PLS WBAHS Please help I do not know how to do this Sasha's grandma is going to sew this umbrella for Sasha. The umbrella is made of 4 identical triangles. If each triangle is 3 feet long and 4 feet high, how many square feet of fabric does Sasha's grandma need? Explain how you found your answer. Which expression is equivaien. to 6 (3x + 4)? A 3 digit number is such that twice the hundreds digit is more than the tens digit by 2.The digit is thrice the hundreds digit.When the digits are reversed, the number is increased by 594.Find the number. 9A canoe with a mass of 120 kg is floating downriver at a speed of 2.5 m/s. What is the canoe's kinetic eergy? In the data set below, what are the lower quartile, the median, and the upper quartile?15 17 41 15 50 55 55 58 62 66 plss help n dont be a B n give me sum gy link :|Solve for x-3x + 6 = 2x - 24A) -30B) -6C) 6D) 30 Day and night occurrence is longshort A newly opened middle schools enrollment is currently at 400 students. However, the school is implementing new programs and incentive systems to attract more students. They are projecting a 125% increase in enrollment for the upcoming school year. How many students does the school project to have for the upcoming school year?I DON'T need the answer, I need to know how you solved it, don't just look up the answer and say that. PLS HELP ME! . This pattern follows the rule multiply by 3, then subtract 4. What are the next two terms? 5, 11, 29 Inside Incorporated was issued a charter on January 15 authorizing the following capital stock: Common stock, $6 par, 100,000 shares, one vote per share Preferred stock, 7 percent, par value $10 per share, 5,000 shares, nonvoting. The following selected transactions were completed during the first year of operations in the order given: a. Issued 21,000 shares of the $6 par common stock at $19 cash per share. b. Issued 3,100 shares of preferred stock at $23 cash per share. c. At the end of the year, the accounts showed net income of $39,000 Prepare the stockholders' equity section of the balance sheet at December 31 How many inches is in 5 1/4 feet PLEASE ANSWER ASAPWhich of the following statements accurately describe a chromosome? Select all that apply.a. Chromosomes contain one long DNA molecule that is tightly woundb. Every chromosome has many genes as each gene is one segment of DNAc. Every chromosome has one gene as an entire DNA makes up a gened. In any given organism, the gene(s) found on one chromosome can also be found on other chromosomes. can someone please help me 2x+1=5x-8 Solving Equations with Many or No Solutions HELP PLS ITS DUE 11:59 Solve and check each equation below . show all work . 24=g+14. f-9=12