Many types of cancer are known to overexpress the receptor protein tyrosine kinase. Which molecular technique can be used to reduce expression of tyrosine kinase in cell culture?

Answers

Answer 1

Answer:

By phosphorylation or by activating cyclin-dependent kinase-mediated signaling pathways

Explanation:

The Cyclin-Dependent Kinases (Cdks) are a family of critical regulatory proteins capable of modulating the progression through the cell cycle. Cdks are in turn regulated by binding to cyclin proteins or by phosphorylation at specific amino acid residues (generally tyrosine and threonine).

Phosphorylation is the most widely studied posttranslational modification and it is known to inhibit (and also activate) protein function, while cyclin-dependent kinases are proteins known to inhibit the activity of Cdks and thereby acting as tumor suppressors by inducing cell death-apoptosis.


Related Questions

A species of spruce tree occupies the same niche at the mouth of a river that a species of pine tree occupies further upstream. One year, several pinecones fall into the river and are carried to the mouth, where they take root and grow amongst the spruce trees. What will be the most likely result of this occurrence

Answers

Answer:

The correct option is: "Either the pine trees or the spruce trees will eventually evolve into a new species."

Explanation:

There will be a competition between spruce trees and pine trees for nutrition and other resources from the environment to grow and spread since they are now occupying the same niche. Overtime, one specie will outlive the other by evolving into a specie that gives it an advantage over the other.  

Answer: bears

Explanation: it’s the answer

5 Points

Great Britain would have a much colder climate than it does if not for the

O A. polar easterlies

B. gulf stream

C. trade winds

D. jet stream

SUBMIT

Answers

Hello There!

Answer:

B. Gulf stream

Explanation:

Great Britain would have a much colder climate than it does if not for the gulf stream.

-Lab-
"Why are cells so small"​

Answers

Answer:

Explanation:

Because we need a lot of cells and if they were big only a small about would fit.

1. In a standard autoclave procedure dry heat is used combined with high pressure
A. True
B. False

2. Household bleach is routinely used in dilution 1:10
A. True.
B. False

Answers

Answer:

1) F, 2)True

Explanation:

1) autoclave uses steam

2) bleach dilute is 1:10

1. It is false that In a standard autoclave procedure dry heat is used combined with high pressure.

2.  It is true that Household bleach is routinely used in dilution 1:10

1. In a standard autoclave procedure, moist heat, not dry heat, is used in combination with high pressure. Autoclaves use steam under high pressure to achieve sterilization by destroying microorganisms and their spores. The high-pressure steam provides effective heat transfer and penetration, ensuring the sterilization of the items being processed.

2. Household bleach is often used in a dilution of 1:10, meaning one part bleach is mixed with nine parts water. This dilution is commonly recommended for various household cleaning and disinfection purposes. It helps to ensure effective disinfection while reducing the potential harmful effects of concentrated bleach.

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Why would damage to the nervous tissue in the spinal cord lead to paralysis?
Damage results in the loss of signals to muscles to produce movement.
Damage results in the inability of the body to differentiate between voluntary and involuntary movement.
Damage results in the inability of the body to produce connective tissue to support movement.
Damage results in the decreased production of actin and myosin for contraction

Answers

Answer:

B. Damage results in the inability of the body to differentiate between voluntary and involuntary movement

Explanation:

Answer:

b

Explanation:


Can someone help me I don’t know which goes with which it’s different structures of the cell membranes

Answers

Answer:

I hoped I helped :))))

Explanation:

A. Extracellular Fluid

B. Hydrophilic Heads

C. Integral Protein

D. Hydrophobic Tails

E. Cytoplasm

F. Carbohydrate

Complete this sentence. The CNS communicates with the body proper through ________. View Available Hint(s) Complete this sentence. The CNS communicates with the body proper through ________. some cranial nerves, some spinal nerves, and some additional nerves that were mentioned but not discussed in the tutorial the spinal nerves but not specifically through the cranial nerves the cranial nerves but not specifically through the spinal nerves some (but not all) of the cranial nerves and some (but not all) of the spinal nerves the cranial nerves and the spinal nerves

Answers

Answer:

The correct answer is - The cranial nerves and the spinal nerves.

Explanation:

The central nervous system or CNS includes the brain and the spinal cord of the nervous system where it takes sensory information, integrates, and responds accordingly. The spinal cord acts as a conduit for signals between the brain and the rest of the body.

Spinal nerves and crania; both play an essential role in taking sensory information and respond accordingly. Spinal nerves are nerves that help in sending motor, sensory, and autonomic signals between the CNS and the body. The cranial nerves supply information to the CNS and then from the CNS to the body.

Thus, the correct answer is - The cranial nerves and the spinal nerves.

Why do processes and activities suddenly change the global temperature?

Answers

Answer:

hey mate here is your answer

Answer:

Earth's temperature depends on the balance between energy entering and leaving the planet’s system. When incoming energy from the sun is absorbed by the Earth system, Earth warms. When the sun’s energy is reflected back into space, Earth avoids warming. When absorbed energy is released back into space, Earth cools. Many factors, both natural and human, can cause changes in Earth’s energy balance, including:

Explanation:

Variations in the sun's energy reaching Earth

   Changes in the reflectivity of Earth’s atmosphere and surface

   Changes in the greenhouse effect, which affects the amount of heat retained by Earth’s atmosphere

Which environmental change is considered short term?

forest fire
ice age
mountain building
solar energy changes

Edunuity

Answers

Answer:

forest fires

Explanation:

An environmental change that occurs quickly and affects organisms immediately (causing behavioral adaptations).

floods, forest fires, blizzards, volcanic eruptions,

Answer: Forest fires[A]

Explanation:

got 100% on the edge2020 Unit Test

have a good day:)

Correctly order the production and transport of sperm through the male reproductive system. Semen is released from the penis. Sperm are produced in the testes. Sperm leave the testes through the semen duct. In the semen duct, fluids from the glands are added to the sperm.

Answers

Answer:

sperm are produced in testes. sperm leaves through the semen duct. In the semen duct,fluids from the glands are added to the sperm. semenis releasedfrom the penis

Answer:

4    semen is realeased through the penis

1      sperm is produced in the testes

2      sper leaves the semen duct

3      fluids from the glands add to the sperm

Explanation:

What type of enzyme can activate another enzyme by adding a phosphate from ATP?

Answers

Answer:

Here my answer goes.......

Explanation:

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates. This process is known as phosphorylation, where the substrate gains a phosphate group and the high-energy ATP molecule donates a phosphate group.

Given the behavior and ecology of this insect, what are some factors that could cause the incidence of Chagas disease to increase in Central and South America in areas like the banana plantation, and why

Answers

Answer and Explanation:

There are many physical elements such as temperature, precipitation, humidity, altitude, vegetation, among others, that influence the presence of the insects that transmit the Chagas diseases. Its transmission seems to be enhanced by other social elements, such as the deficiency in basic services, lack of planning, the socio-economical conditions, cultural conditions. Altogether, these factors intervene in the presence of the Chagas disease, a systemic infection caused by the protozoa Trypanosoma cruzi. This protozoan is hosted by different wild and domestic mammals, transmitted to the human by hematophagous insects. The transmission occurs through dejections deposited on skin or mucose during or after the feeding process.  

Different rural areas in Central and South America are characterized by a mountain relief (temperatures between 15 and 30ºC - relative humidity between 50 and 90%), as well as by a plane relief associated with alluvial plain (temperature between 20 and 35ºC - media relative humidity of 75%). Vegetation in the mountain area provides a natural habitat to the triatomines, the insects that transmit the Chagas disease.  

Constant deforestation in mountains, soil move, the cutting down, firing, have destroyed the natural habitat of the insects, becomming the cause of their arrival to populated centers. As their environment is destroyed,    insects migrate to new areas and find refuge in precarious houses that surround the affected areas. Most of these houses have clay walls, a roof made of branches, and no floor. People that live in these conditions do not have economic resources.  Indexes of infestation in these houses are high due to the material used for their construction. Insects tend to establish near a source of food, such as domestic animals or even humans. It is also common that these houses have chicken coops and farmyards that also offer good conditions for the insects to live in.

Economic activities are important variables to consider, as these define the way of living in a population.  

Agriculture activities are performed with no control or planning. People deforest to plant, getting in contact with the insects' natural habitat, producing environmental changes, and getting in touch with them, enhancing the risks of being infected and of transportin the insects.

How have the fields of biotechnology, genetic engineering, and molecular biology affected the agricultural job
market?
A.They have created more jobs
B.They have spread the industry internationally
C.They have made the market obsolete
D.They have decrease the demand for farmers

Answers

I think answer should be d.let me know if it’s correct thanks okay bye

Answer:

I think It's A. Hope it helps! :)

Explanation:

After getting their results in, a group of scientists went back and looked at their study. As planned, their experiment consisted of three groups. The first group received a new medicine at a normal dose, the second group received the medicine at half the dose, and the third group received the medicine at twice the dose. Which of the following best describes what went wrong with the scientists’ study?

Answers

Answer:

Their experimental design lacks control group

Explanation:

Based on what I read, the scientists don't have a control group as one of the main groups thus they cannot, in scientific sense, say that the medicine is better or worse. You always need a control group receiving no intervention because then we can compare groups and assess the effectiveness of that intervention (in our case if we had control group vs people who received the medicine, we could see if the people who received the medicine had improved condition etc when compared to participants who did not receive anything)

There is no control group in their experimental design. According to what I've read, the scientists don't have a control group as one of the primary groups. Thus, option C is correct.

What is control group?

To determine if the treatment is better or worse in a formal scientific sense. You should always have a control group that does not receive any treatment because this allows us.

To compare the groups and evaluate the effectiveness of the intervention. In our case, if we had a control group and participants who did not receive any treatment, we could see if those participants had better health overall.

By focusing on the impact of a single independent variable, a cause-and-effect link can be established.

The independent variable is altered in the treatment group while being held constant in the control group by researchers. The findings of these groups are then compared.

Therefore, no control group in their experimental design.

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