In the active site of the enzyme lotzase, a mutation of lysine 132 toaspartic acid causes a loss of lotzase function. Lotzase is most catalytically active at pH 7. Which is the following is the best reason why this might occur?
a. a negative charge is needed for substrate binding.
b. a positive charge is needed for substrate binding.
c. a general acid is needed for catalysis to occur.
d. more than one of the following can be a good reason.

Answers

Answer 1

Answer:

B. positive charge is needed for substrate binding

C. a general acid is needed for catalysis to occur

Explanation:

A mutation of lysine 132 toaspartic acid causes a loss of lotzase function as a result of the enzyme lotzase being most catalytically active at pH 7( neutral).

This condition is however achieved under conditions such as a positive charge being involved in the substrate binding and a general acid being involved in the catalytic process.


Related Questions

How is the top layer of the ocean different than the deepest layer
A the top layer is colder and doesn’t receive sunlight
B the top layer receives sunlight and is warmer
C the top layer is warmer and doesn’t receive sunlight
D the top layer is colder and receives sunlight

Answers

Answer:

B the top layer receives sunlight and is warmer

Explanation:

Answer:

B. the top layer receives sunlight and is warmer.

5.
is the process by which artificial means are used to protect an individual
from a specific disease.
Cowpox
b. Microbes
c. Vaccination
a.

Answers

Answer c..Vaccination

Explanation:

A friend comes to you extremely agitated and says her husband beat her last night.She says she doesn't know what to do.You Can See She's Very panicky.Everything you suggest just seems to provoke more anxiety and fears.When you try to respond to one aspect of the problem.Your friend interrupt's frantically and jumps to another.Explain what can you do to help.

Answers

Let her get it all out and then try to help her . If she keeps panicking u might wanna take her to get some help

Uncellular eukaryotic organisms belong to?

Answers

All eukaryotic unicellular organisms belong to Protista.

Answer:

Unicellular eukaryotic organisms belong to kingdom protista.

Explanation:

Unicellular eukaryotic organisms belong to kingdom protista. They depend on other organisms for their food since they're not able to produce their own.

Hope this helps :)

A chemical reaction is an interaction that always causes:
O A. matter to be changed into energy.
B. macromolecules to be formed from glucose.
O C. molecules to break apart into atoms.
O D. atoms to be rearranged into new substances.

Answers

Answer:

D. atoms to be rearranged into new substances.

Explanation:

Chemical reactions involve interaction between chemicals such that all reactants are changed into new materials. The properties of the new materials are different from those of the reactants.

Chemical reactions involve breaking chemical bonds between reactant molecules (particles) and forming new bonds between atoms in product particles (molecules). The number of atoms before and after the chemical change is the same but the number of molecules will change.

True or false. If Americans decided to eat more chicken and less beef, the future size of the chicken population would increase and the cattle population decline. True False True or false. Resources that are commonly owned are likely to be over-utilized and poorly maintained. True False True or false: Ocean fisheries are generally owned in common; as a result, the quantity of various species such as salmon are often overfished.

Answers

Answer:

The given first statement is true, that is, with the increase in the demand for chicken, the chicken market will rise, and in the same way with the decline in the demand for beef, the production of cattle will decrease based on the law of demand.  

The given second statement is also true, as the resources mentioned in the given statement is a tragedy of commons as the common access resources are rivalrous and non-excludable.  

The given third statement is also true, as the mentioned ocean fisheries is a tragedy of commons as the common access resources are rivalrous and non-excludable.  

As Hite and Seitz (2016) discuss in Chapter 5: Climate Change, reputable scientific studies continue to show that the Earth is warming at an unsustainable rate because of a rise in the release of CO2 and methane gases. What is the relationship between population increases and climate change

Answers

Answer:

See the answer below

Explanation:

The relationship between climate change and increased population of humans is a direct one. As the population of humans increases, their activities leading to the release of greenhouse gases such as CO2 and methane also increases. The greenhouse gases are primarily responsible for the warming of the earth.

As more and more greenhouse gases are released into the atmosphere, more radiation from the sun is trapped in the atmosphere and the earth receives more warmth. This extra heat received leads to increase in the global temperature, a phenomenon known as global warming. As the average global temperature increases, climate becomes more erratic and unpredictable.

The greenhouse gases-related activities of humans that are bound to increase with the increase in population include deforestation, fossil fuel burning, industrialization, etc.

List the functions of proteins

Answers

Answer:

Growth and Maintenance.

Causes Biochemical Reactions.

Acts as a Messenger.

Provides Structure.

Maintains Proper pH.

Balances Fluids.

Bolsters Immune Health.

Transports and Stores Nutrients.

What was the population density of the original sample? What would have happened if you had inoculated an agar plate with 1 mL of the original sample?

Answers

Answer:

The sample was at a population density of 8.75x10^4 CFU/mL originally.

Explanation:

Had it been inoculated in the way as described in the question statement, the bacterial growth would have covered all of the agar plate and we would not have been able to distinguish individual colonies of bacteria. 1 mL is too much of a sample volume to use in cases like these.

A circular double-stranded DNA molecule contains 4200 base pairs. In solution, DNA is in a B-form helix, with about 10.5 base pairs/turn. The DNA has 12 superhelical turns. What is its superhelix density

Answers

Answer:

The correct answer is - 3 × 10⁻²

Explanation:

first find LKo = length of BDNA/ 10.5 bp/turn

= 4200/10.5

= 400

now calculate Δ LK= LK - LKo

ΔLK = 412-400

ΔLK = 12

now, superhelix density  = ΔLK/LKo

⇒ 12/400 = 0.03

= 3×10⁻²

Thus, the correct answer is - 3 × 10⁻²

what is a part of interphase A. cytokinesis B. telophase C. anaphase D. s phase

Answers

Answer:

D

Explanation:

I did it on my own soci know it's the answer

In the context of interphase, the S phase is the specific part where DNA replication occurs, contributing to the overall process of cell division and ensuring the transmission of genetic material to new cells and the correct option is option D.

Interphase is the longest phase of the cell cycle, and it is divided into three main stages: G1 phase, S phase, and G2 phase. Among these stages, the S phase is specifically responsible for DNA replication. It is during the S phase that the cell's DNA is duplicated in order to prepare for cell division.

During the S phase, the DNA helix unwinds, and the two strands separate. Enzymes and proteins then work together to synthesize new complementary strands for each of the separated DNA strands. As a result, two identical copies of the DNA molecule are produced.

The S phase plays a crucial role in maintaining the genetic integrity of the cell. By accurately duplicating the DNA, the cell ensures that each daughter cell formed during cell division receives an identical set of genetic information. This is vital for the proper functioning and development of organisms.

Thus, the ideal selection is option D.

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why was an Archea considered as a prokaryote ​

Answers

Answer:

Archaea is prokaryotic because it doesn't have a nucleus, nor any membrane-bound organelles. The reason why Archaea is different from Bacteria is it is more prominent, most of them are extremophiles.

because they are composed of cell which doesn't have nucleus and other some cell organelles and also considered as incomplte cell.

The graph below shows the temperature of ocean water at different depths. Which part of the graph represents the thermocline? a. AB b. BC c. CD d. DE

Answers

Answer:

C

Explanation:

Generally temperature changes rapidly with the dept in aquatic bodies especially the oceans.The thin distinct or transition layer where the variation in temperature with depth is most significant is called Thermocline.

Its represents the gaps which  separate   the upper mixed layer from the lower deeper water bed below,it therefore represent the layer of mixture of the upper surface warmer water (C) below 200 meters, with the  cooler water layer(E) below,from 1000 meters check the attachment.

It is caused by variation in intensity of sunlight.The latter hits the surface water layer and therefore raises the temperature.But,because of decrease in  sunlight penetration,with  increasing  dept, the temperature of the  lower water dept decreases.

which type of research study compares disease rates among population groups?

Answers

Answer:

Epidemiological

Explanation:

Epidemiology compares disease rates among population groups, and attempts to identify related conditions or behaviors.

Answer: Epidemiological studies

Huntington's disease, which causes degeneration of neurons, runs in Mark's family. Huntington's is a heritable autosomal dominant genetic disease, in an autosomal dominant disease, only one abnormal allele is required to cause the disease in offspring. However, it is possible not all offspring will receive the abnormal allele from an affected heterozygous parent.
Family members that have the disease include Mark's maternal grandfather and Mark's maternal aunts. Mark's maternal grandmother does not have the disease.
Because symptoms of Huntington's disease do not appear until later in life, genetic testing is necessary to determine whether a younger individual possesses the allele for the disease. These tests determined that Mark's mother does not carry the allele for Huntington's disease.
Mark's paternal aunt suggested that Mark create a pedigree to track the disease in his family. Use the symbols provided to complete the pedigree. Each symbol may be used more than once.

Answers

Answer:

As it is given that Mark's paternal grandmother and grandfather does not carry the disease. The symbols on the right side of the Punnett represent Mark's paternal family. If both his paternal grandparents are unaffected then his father and paternal aunt are also not affected by the disease.

His maternal grandfather is affected as mentioned and also his maternal aunts are affected. Mark's mother is unaffected as she does not have the disease-causing alleles determined by genetic testing.

Both of the marks parents are unaffected which indicates that marks also do not carry the allele of the disease.

Huntington's disease is an autosomal dominant disorder in which the presence of even one dominant allele can cause the disorder.

The autosomal disorder can not skip a generation, have to be present in every generation.

Condition Given:

Affected Member: Mark's Maternal grandfather and Maternal aunts.

Normal: Mark's Maternal grandmother and Mark's Mother.

As MArk's Maternal Grandfather is affected then his genotype must be Aa because Mark's Maternal grandmother is unaffected (aa), this is the only condition where Mark's mother will be normal.

A- Dominant (Huntington)

a- Recessive

Maternal means on the mother's side and paternal means on the father's side.

The diagram is attached below.

I-1: Mark's maternal Grandmother

I-2: Mark's maternal Grandfather

I-3&4: Mark's Paternal Grandparents

II-1&2: Mark's Maternal aunts

II-5: Mark's paternal aunt

II-3&4: Mark's mother and father respectively will not have the disease as both father and mother of Mark are normal.

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Which activity involves a chemical change?
A. Ice melting into liquid water
B. A metal rod being bent into a ring
C. Colorless egg becoming a white solid
D. Salt dissolving in water
SUBMIT
Need help now pls!!

Answers

option C is correct........

.. Please follow me and mark as brainliest

difference between plant and animal cyanide resistance respiration.

Answers

Answer:

The cyanide resistant respiration differs in plants as oxi­dation of reduced coenzyme continues even in the presence of cyanides.

Explanation:

The mitochondrial is the electrons through which the animals and plants perform the aerobic exercise and is blocked by the release of the cyanides that stops the activity and is known as cyanide sensitive respiration Plant mitochondria is different from the animal as they both have different oxidase system pathways. Cyanide resistant is responsible for the climacteric in fruits and for the generate heat in thermogenic tissues.

What is a possible effect of long-term environmental changes?
adaptation
migration
habitat loss
starvation

Answers

Answer:

adaptation

Explanation:

did the pre test

Long-term environmental changes can have various effects on the organisms and ecosystems that inhabit them, and one possible effect is habitat loss, which is the third option.

What are environmental changes?

Long-term environmental changes are changes that occur gradually over time, such as changes in temperature, rainfall patterns, or atmospheric conditions, and can have significant impacts on ecosystems and the organisms that inhabit them. One of the primary effects of long-term environmental changes is habitat loss. For example, climate change is leading to melting ice caps, rising sea levels, and changes in weather patterns, which can impact habitats such as coral reefs, forests, and wetlands, causing them to shrink or disappear. This can result in the loss of habitat for many species, leading to declines in their populations and potential extinction.

Hence, long-term environmental changes can have various effects on the organisms and ecosystems that inhabit them, and one possible effect is habitat loss, which is the third option.

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Which effect is most likely to occur as a result of clear-
cutting?
extinction of species
death of organisms
speciation
global warming

Answers

Answer:

Death of organism

Explanation:

Human activities include the clear-cutting of areas of forest to make space for farming.

Which effect is most likely to occur as a result of clear-cutting?

Is this your question?

Death of organisms effect is most likely to occur as a result of clear-cutting.

What do you mean by clearcutting?

Clearcutting is an extreme logging method in which resilient natural forests are harvested and replaced with man-made tree plantations that do not replicate the ecosystem services of a healthy forest.

Clearcutting is one of the most publicly maligned and misunderstood forest regeneration treatments. It is the only way to grow trees that require full sunlight to reproduce, such as tulip poplar, black cherry, and aspen, and the fastest way to provide/create shrubland habitat.

Clear-cutting often contributes to reductions in root strength and soil water-holding capacity, due to soil compaction and reduced transpiration. Moreover, the removal of the forest cover exposes the soil surface to heavy precipitation and large variations in temperature.

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Jessica weighs 125 pounds. She rode a bike at 17mph for 25 minutes. What is the calorie cost of this activity?
a. 185 calories
b. 178 calories
c. 180 calories
d. 190 calories
e. 188 calories

Answers

Answer:

b. 178 calories

ok so 17mph is 0.57 weight/min

so what were going to do is multiply 125 times 0.57 which is 7.125

then multiple that answer by 25 mintues: 7.125 x 25 = 178.12...etc

now if we round this up it stays as 178!

Which event is associated with tornados?
sea levels rising due to high waves
coastal flooding due to storm surge
paths of damage up to 50 miles long
wind and rain lasting for several days
Helpppp

Answers

Paths of damage up to 50 miles long

According to the question, paths of damage up to 50 miles long is correct.

The destructive power of storm surge and large battering waves can result in loss of life, buildings destroyed.

Are tornadoes increasing in frequency?

There's been no observed increase in the frequency of major tornadoes over time.

Thus, option "C" is correct.

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Which structure of a paramecium is analogous to a “reserve copy” of all the cell’s genes

Answers

Answer:

micro nucleus

Explanation:

 What is the most likely explanation for how speciation occurs?
A. It occurs by more than one method.
B. It occurs by gradual changes.
C. It occurs only by geographic isolation.
D. It occurs only by natural selection.

Answers

Answer:

The answer is (C) geographical isolation

Explanation:

Speciation is most likely to occur when populations become geographically isolated from one another, and come to inhabit environments that differ significantly from one another.

which describes a meta phase plate

Answers

Answer:Metaphase plate refers to sister chromatids lining up in the center of the cell. This event occurs during the metaphase of the cell division and it is the indication of this phase. Metaphase plate is a moment when all of the chromosomes organize, line up literally in a row and after that begin to.

What best describes the behavior of nonconservative elements in seawater?

Answers

The given question is incomplete due to missing options, however, the options for the question as follows:

A. Nonconservative elements are reactive in seawater and have a long residence time.

B. Nonconservative elements are reactive in seawater and have a short residence time.

C. Nonconservative elements are non-reactive in seawater and have a short residence time.

D. Nonconservative elements are non-reactive in seawater and have a long residence time.

Answer:

The correct answer is option C.

Explanation:

Non conservative components are components that enter the ocean water and have little concentration in the sea and show spatial variations. These components have short home time that is short replacements time and they are non responsive.

Constituents, for example, phosphate, nitrate, and different supplements, and broke up oxygen, carbon dioxide, and so on are non-conservative on the grounds that their concentrations are later altered by chemical reactions in the ocean.

Thus, The correct answer is option C.

A microbiologist would like to use a noncompetent genus of streptococcal bacteria, Enterococcus faecalis, as a cloning host to express genes from Streptococcus pneumoniae, which is naturally competent. Is this possible? Group of answer choices

Answers

Answer:

Yes, with the assistance of electroporation the bacteria Enterococcus can be made competent, and afterward, the Streptococcus bacterial genes can be presented within the Enterococcus with the help of a cloning vector.  

The electropermeabilization or electroporation refers to a microbiology technique in which the permeability of the cell membrane is enhanced with the application of the electric field. This permits drugs, chemicals, or DNA to get presented within the cell.  

The procedure of electroporation is generally used in the field of microbiology to transform yeast, bacteria, or protoplasts of plants by presenting novel coding DNA.  

The first glycolysis rate-limiting enzyme is under various allosteric regulations. This protein is nearly inactive because of inhibition by ( ) under physiological conditions. The activity is restored by ( ), its most potent allosteric activator.

a. AMP :::: citrate
b. AMP :::: Fru-2,6-P2
c. ATP :::: citrate
d. ATP :::: Fru-2,6-P2
e. All of these

Answers

Answer:

d. ATP;  Fructose-2,6-bisphosphate

Explanation:

Phosphofructokinase-1 is the enzyme that catalyzes the formation of fructose-1,6-bisphosphate from fructose-6-phosphate and ATP. The phosphofructokinase step is the first rate-limiting step of glycolysis.

Phosphofructokinase-1 activity is allosterically regulated. Its activity is increased whenever the cell's ATP supply is depleted or when its breakdown products, ADP and AMP accuulates in he cell. However, it is inhibited when the cell is amply supplied with ATP.

The activity of phosphofructokinase-1 is restored by fructose-2,6-bisphosphate, its most potent activator.

From the given options:

a. AMP :::: citrate  is wrong because AMP increases the activity of phosphofructokinase-1 and citrate is not its activator but an inhibitor

b. AMP :::: Fru-2,6-P2  is wrong because AMP increases its activity same as fructose-2,6-bisphosphate

c. ATP :::: citrate  is wrong because both citrate and ATP are inhibitors

d. ATP :::: Fru-2,6-P2  is correct as explained above

e. All of these is wrong because of the other wrong options above.

The mechanism by which proteins synthesized in the cytosol are imported into the mitochondrial matrix is different from the mechanism by which proteins enter the nucleus, yet the two mechanisms do share some features. Indicate whether each of the following statements applies to nuclear import, mitochondrial import, both, or neither. Sort each statement into the appropriate bin.
1. The polypeptide to be transported into the organelle has a specific short stretch of amino acids that targets the polypeptide to the organelle.
2. The imported protein enters the organelle through some sort of protein pore
3. The pore complex consists of more than two dozen proteins and is large enough to be readily seen with the electron microscope.
4. ATP hydrolysis is known to be required for the translocation process
5. The signal sequence is always at the olypeptide's N-terminus and is cut off by a peptidase within the organelle
6. The signal sequence is recognized
GTP hydrolysis is known to be required for the translocation process
7. There is strong evidence for the involvement of chaperone proteins polypeptide's N-terminus and isctand bound by a receptor protein inrequired for the translocation during translocation of the protein the organelle's outer membrane process.
Nuclear import Mitochondrial import Both Neither

Answers

Answer:

Nuclear import:

1. GTP hydrolysis is known to be required for the translocation process

2. The pore complex consists of more than two dozen proteins and is large enough to be readily seen through electron microscopy

Mitochondrial import:

1. ATP hydrolysis is known to be required for the translocation process

2. The signal sequence is always at the polypeptide's N-terminus and is cut off by a peptidase inside the organelle

3. There is strong evidence for the involvement of chaperones during the translocation process

4. The signal sequence is recognized and bound by a receptor protein in the organelles outer membrane

Both:

1. The polypeptide to be transferred into the organelle has a specific short stretch of amino acids that targets the polypeptide to the organelle

2. The imported protein enters the organelle through some sort of protein pore

Explanation:

Which center bears the primary responsibility for generating the respiratory rhythm, but is influenced by several other centers

Answers

Answer:

This is the Ventral Regulatory Group-VRG

Explanation:

In the medulla,there are four groups of neurons which forms the exhalation parts of the   respiratory  control.These 4 groups are called the VRG.They occupy 5mm anterior in length, and laterally positioned to the dorsal respiratory group.They are therefore said to occupy the ventrolateral part of the medulla.

The dorsal respiratory group(DRG) consists of the inspiration neurons,contrary to the VRG. They do not extend to the DRG,but the DRG, extends to them

They(VRG) function in propagating action potentials needed for the mechanisms of respiration.(exhalations), and Inspirations

1.

behavior is inherited and



2. When a deer hears a sound in the forest, such a

then bolts through the bushes. This is an examp

3. Mating rituals or displays can be very complex

4. When animals fight and one wins and one subm

This means that one animal (the winn

behavior is used to intimidate other an

baring teeth or growling.

Answers

Answer:

Behavior is inherited in many animals which helps them to survive.

Explanation:

When animals fight with one another and one wins. This means that one animal (the winner) behavior is used to intimidate other. Two deer fight each other in order to show dominance over each other and to impress the female deer. The winner deer will be the leader and also mate with the females of the group. This is a type of behavior which is inherited in animals through genetics is called instincts.

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When JFCs consider incorporating combinations of contiguous and noncontiguous AOs with linear and nonlinear operations, they choose the combination that fits the operational environment and the purpose of the operation. Which of the following combinations describe a typical sustained offensive and defensive operation against powerful, echeloned, and symmetrically organized forces and where the forward line of own troops focus combat power and protect sustainment functions?1. Nonlinear operations in noncontiguous AOs 2. Nonlinear operations in contiguous AOs 3. Linear operations in contiguous 4. AOs linear operations in noncontiguous AOs Which statement could the expression n + 1 represent? one point greater than the last test grade the difference of Gina's score and one the total cost less one dollar one minute less than Mickey's previous time What can happen if a body moves through speed of light In triangle ABC, the right angle is at vertex C, a = 714 cm and the measure of angle A is 78 . To the nearest cm, what is the length of side c? An insurance company models the number of warranty claims in a week on a particular product that has a Poisson distribution with mean 4. Each warranty claim results in a payment of 1 by the insurer. Calculate the expected total payment by the insurer on the warranty claims in a week. Find the critical value z Subscript alpha divided by 2 that corresponds to the given confidence level. 80% Please help me I would appreciate it Which observation have scientists used to support Einstein's general theory of relativity?The orbital path of Mercury around the Sun has changed.O GPS clocks function at the same rate on both Earth and in space.O The Sun has gotten more massive over time.Objects act differently in a gravity field than in an accelerating reference frame. Simplify: |4-5| / 9 3 - 2/5 a.61/10 b.13/5 c.11/10 d.-2/15 What wasWhich technological advance did not become popular in the 1920s? Gemma is creating a histogram based on the table below. Salary Range Number of People 0 - $19,999 40 $20,000 - $39,999 30 $40,000 - $59,999 35 Which scale can she use for the vertical axis such that the difference in the heights of the bars is maximized? 050 040 1050 2540 Which sentence in this excerpt from Common Sense by Thomas Paine supports the claim that the American colonies could thrive independently from Britain? I have heard it asserted by some, that as America hath flourished under her former connection with Great Britain that the same connection is necessary towards her future happiness, and will always have the same effect. Nothing can be more fallacious than this kind of argument. We may as well assert that because a child has thrived upon milk that it is never to have meat, or that the first twenty years of our lives is to become a precedent for the next twenty. But even this is admitting more than is true, for I answer roundly, that America would have flourished as much, and probably much more, had no European power had any thing to do with her. The commerce, by which she hath enriched herself, are the necessaries of life, and will always have a market while eating is the custom of Europe. In this problem, y = c1ex + c2ex is a two-parameter family of solutions of the second-order DE y'' y = 0. Find a solution of the second-order IVP consisting of this differential equation and the given initial conditions. y(1) = 9, y'(1) = 9 For a fluid flowing through a pipe assuming that pressure drop per unit length of pipe (P/L) depends on the diameter of the pipe , the velocity of fluid, the density of fluid and the viscosity of the fluid. Show that = TRANSFORMA LAS SIGUIENTES ORACIONES EN ESTILO INDIRECTO: LUCA ME DIJO: CREO QUE EN ESTE MOMENTO NECESITO UN CAMBIO EN MI VIDA. EL MDICO LE DIJO AL PACIENTE: DEBE REALIZARSE ESTOS EXAMENES SIN DEMORA. A tightly wound toroid of inner radius 1.2 cm and outer radius 2.4 cm has 960 turns of wire and carries a current of 2.5 A.Requried:a. What is the magnetic field at a distance of 0.9 cm from the center?b. What is the field 1.2 cm from the center? How many positive integers of 3 digits each can be formed with the digits 1, 8, 9, 2, 7, 6, 4, and 3, if no digit is repeated in a number? 1. 27 2. 512 3. 336 Question 3 of 102 PointsIf h(x) =(fg)(x) and h(x) = 3(x + 2), find one possibility for f (x) and g(x). The thermochemical equation is for the reaction of hydrogen bromide gas to form hydrogen gas and bromine liquid. 2HBr(g) = H 2 (g)+ Br 2 (l) 72.6 kJ How many grams of HBr (g) would be made to react if 11.4 energy were provided? Si incrementa 35% los precio de un restaurante.Si un salmn a la mostaza lo venda en 28,50 y un pollo al curry en 32,80cuales sern los nuevos precios de estos platos?cual sera el monto neto que recibir por plato sin incluir el 18%de igv?