Explain why mutations that replace S/T/N residues with A/L/W residues in the N-terminal region of transmembrane proteins that function as cell surface receptors could significantly disrupt that utility of these proteins as receptors.

Answers

Answer 1

Answer:

Serine (S), Threonine (T) and Asparagine (N) are primary binding sites of carbohydrates, and thereby they are required to form glycoproteins (i.e., glycosylation products)

Explanation:

A transmembrane protein (TP) is a particular type of protein that crosses the cell membrane in order to enable the movement of ions and molecules. Transmembrane proteins are divided into alpha-helical and beta-barrel proteins. The N-terminal region of transmembrane glycoproteins can be required for N-linked glycosylation, which is an enzymatic mechanism capable of attaching oligosaccharides to proteins in order to form glycoproteins (glycans). N-linked glycosylation is a posttranslational protein modification that has distinct functions depending on the cell type and the protein region involved in such modification. For example, in the surface of immune cells, the N-linked glycans are capable of dictating the migration pattern of these cells.


Related Questions

Somatic cells in elephants have 56 chromosomes. How many chromosomes would be carried by the gametes produced by elephants

Answers

Answer:

As somatic cells are diploid (2n) 2n=56

gametes receive only haploid set so, n=28

The number of chromosomes carried by the gametes produced by elephants would be :  28

Given that The elephants posses 56 chromosomes in its somatic cells and somatic cells are known as diploid cells ( i.e. 2n ) while the gametes will only carry a haploid set of chromosome ( i.e. n ).

Determining the number of chromosomes contained in the gametes

 since ; 2n ( chromosomes of a somatic cell ) = 56

n ( chromosomes contained in a gamete ) = 56 / 2 = 28

Hence we can conclude that The number of chromosomes carried by the gametes produced by elephants would be :  28.

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How do plants get the nitrogen they need?

A.
From bacteria living in their roots

B.
From the air

C.
Directly from the soil

D.
Through photosynthesis

Answers

the answer is C. because active transport happens at roots
The answer is Directly from the soil

How can protists exhibit both animal-like and plant-like characteristics?

Answers

A heterotrophic and chlorophyll protist

Food is ingested by protists in three forms. We produce, eat and digest their own organic molecules. Meat ingestion or english bacteria ingests protists. The cell wall and cell membrane are stretched to create an alimentary vacuolum around the foodstuff. Enzymes extract the food inside the food vacuole. At the other side, absorbent protists consume food molecules through their cell membrane by diffusion. In decomposition, absorbent protists play a crucial role. They are assumed to be essential decomponents. Light energy is used to make your own food by big farmers including photosynthetic protists.

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Which statement best describes how Watson and Crick's model used other scientists work to create a model of DNA?
They used Chargaff's rule to determine that it contains ribose sugar
O They used Franklin's photo to determine that DNA was a double helix.
They used Levene's work to determine the number of base pairs in each strand.
O They used Nirenberg and Matthei's studies to determine that DNA is made of nucleotides.

Answers

Answer:

b.

Explanation:

They used Franklin's photo to determine that DNA was a double helix.

The best statement that describes how Watson and Crick's model used other scientists' work to create a model of DNA can be seen in the second Option.

They used Franklin's photo to determine that DNA was a double helix.

               The early 1950s saw the development of the renowned model of the DNA double helix by American scientist James Watson and British physicist Francis Crick. They were the explorers to pass the finishing line in this scientific race.

               Rather than doing fresh tests and experiments in the lab, Watson and Crick primarily gathered and evaluated existing data, combining it in novel and illuminating ways.

               Franklin was a specialist in X-ray crystallography, a sophisticated approach for identifying molecular structures. When an X-ray beam strikes the crystallized form of a molecule, e.g the DNA, part of the rays are redirected and diverted by the atoms in the crystal, creating a diffraction pattern that unveils data information regarding the structure of the molecule.

               Franklin's crystallography provided crucial hints to Watson and Crick on the structure of the DNA model. Some of them originated from Franklin's extraordinarily clear and stunning X-ray diffraction photo of DNA.

               According to the work of Phoebus Levene, Levene only posits that the DNA was formed of subunits called nucleotides.

               Erwin Chargaff speaks volumes on the determination of the composition of ribose sugar bases.

               Therefore, we can conclude that Watson and Crick knew about all these Phoebus Levene and Erwin Chargaff postulates and experiments but it was Franklin's work on X-ray diffraction photos of DNA that gave them a crucial hint to create a model for the DNA.

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Answers

Answer:

[tex]\boxed{Option \ 2}[/tex]

Explanation:

=> In the first graph, we come to know that winters are colder and summers are hotter.

=> In the second graph, winters have more precipitation than summer.

=> On the whole, Winters have lower temperature and more precipitation than summers.     ← [Option 2]

=> Summers have high temperatures and less precipitation.

Answer:

[tex]\boxed{\sf Option \ 2}[/tex]

Explanation:

We can see in the first graph that the winter months have a lower temperature compared to the summer months. The summer months have higher temperatures.

In the second graph, the winter months have much higher average precipitation compared to the summer months. The summer months have lower average precipitation.

Winters have lower temperatures and more precipitation than summers.

Classify each nutrient as a macronutrient or as a micronutrient

Answers

Answer:

Macro: Phosphorous, Protein, Fat, Carbohydrates

Micro: Vitamin A, Sodium

Explanation:

Macronutrients are nutrients that are needed in large amounts. Micronutrients are needed in smaller amounts.

Why does deleting just one nucleotide cause a dramatic change in the amino acid sequence produced by translation

Answers

Answer:

The deletion changes the genetic code.

Explanation:

The sequence of nucleotides determines the order of amino acids in a protein, the order of amino acids determines the shape and the shape determines the function. A very good example of one misplaced nucleotide having tremendous effects is sickle cell disease, where thymine is replaced with adenine(CAC instead of CTC). It means that glutamic acid is replaced with valine. This alters the shape of the protein(Beta chain of hemoglobin). So the red blood cells are deformed and carry a lot less oxygen leading to a lot of symptoms just because of one misplaced letter.

a strand of dna contains the base sequence AGTT . What is the sequence of the complimentary strand of DNA

Answers

Answer:

The sequence is TCAA

Explanation:

Deoxyribonucleic acid (DNA) is a molecule composed of two complementary chains of nucleotides. The nucleotides are in turn composed of one nitrogenous base, one deoxyribose sugar, and one phosphate group. The four different types of nitrogen bases found in DNA are thymine (substituted by Uracil during RNA transcription), adenine, cytosine and guanine. These bases bind by complementary base pairing to form an antiparallel double-strand. The complementary base pairing rule states that thymine forms two hydrogen bonds with adenine, while cytosine forms three hydrogen bonds with guanine.

Answer:

TCAA

Explanation:

A matches to T and G matches to C.

A mutation causes a sequence of DNA that has the nucleotides TTG to be changed to TCG. The resulting protein has a different sequence of amino acids. Which type of mutation is this?

Answers

Answer:

subtitution mutation

Explanation:

The T in the middle is subtituted with C.

Hope it helps.

Answer:

The answer is A, missense.

Explanation:

The iris in the human eye contracts and expands, controlling the amount of light that reaches the retina. What types of muscle control this?To which skeletal system does the sternum belong?

Answers

Answer:

1. sphincter muscle and dilator muscle

2. Axial skeleton

Explanation:

1.The iris in the human eye is responsible for controlling the exposure of of light that reaches the retina. The movement of iris is controlled by a muscles called sphincter muscle and dilator muscle. sphincter muscle constricts the pupil in bright light while dilator muscle expands the pupil.

2.  Sternum belongs to the axial skeleton, which is a long flat bone located in the central part of the chest. Axial skeleton consists of 80 bones and strenum is one of them. Axial skeleton functions to provide protection to vital organs such as brain, heart and lungs. Strenum functions to protect heart.

Which of the following processes requires energy from the cell?

A.
Osmosis

B.
Active transport

C.
Diffusion

D.
Passive transport

Answers

The following processes requires energy from the cell - B. active transport

Active transport is used by cells to get required molecules such as glucose and amino acids. It requires energy in form of adenosine triphosphate (ATP) is known as primary active transport.

Active Transport works against the concentration gradient and therefore needs energy.Passive transport such as Diffusion and Osmosis, from areas of high concentration to areas of low concentration without the need for energy

Thus, the following processes requires energy from the cell - B. active transport.

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DNA and RNA are structurally similar in some ways, but different in others. Identify whether each of the following statements applies to DNA, RNA, both or neither.
1. It can contain the pyrimidine cytosine.
2. It can contain the pyrimidine uracil.
3. This contains the sugar 2'-deoxyribose.
4. In terms of base composition, the %A = %C.
5. This contains the sugar ribose.
6. The bases are attached to sugars in a beta-N-glycosidic linkage.
7. It contains equal amounts of guanine and cytosine.
8. Sugars are connected with a 3'-5' phosphodiether link.

Answers

Answer:

Explanation:

1. It can contain the pyrimidine cytosine - Both

2. It can contain the pyrimidine uracil - RNA

3. This contains the sugar 2'-deoxyribose - DNA

4. In terms of base composition, the %A = %C - Neither: %A = %T

5. This contains the sugar ribose - RNA

6. The bases are attached to sugars in a beta-N-glycosidic linkage - Both

7. It contains equal amounts of guanine and cytosine - Both

8. Sugars are connected with a 3'-5' phosphodiether link - Neither: they are connected by a 3'-5' phosphodiester link


Which of the following statements best describes communication style versatility?
The early bird gets the worm.
You can t judge a book by its cover.
I cannot control you, but I can control myself
alf a loa better than none​

Answers

Answer:

I cannot control you but I can control myself.

Explanation:

Communication style versality is the ability to identify and understand way or taste of communication and adapt to it in order to make people open and receptive to it there by creating intimate relationships with people.

The features of communication style versality is I cannot control you but I can control myself in the sense that I will have to understand different styles and communication preference, then adapt to it by controlling myself, in me controlling myself people will tend to be open and receptive to it and intimate relationships will be built. I can't control other people but I will have to control or work on myself.

What does environmental quality refer to? Environmental quality refers to the quality of the total environment, including both the natural and the environment.

Answers

Answer:

True,

An animal requires, Food, Water, Shelter as basics of life - but I add a third, for social animals; a Mate, Young, or Flock/Herd/Group

Which type of organism developed first?

Answers

al

answer: algae

explanation: because the were the first ones to adapt with water and land...

Explain the mechanism responsible for summation of contractions and the increase in height of contraction when the stimulus frequency is increased.

Answers

Answer:

The higher the stimulation frequency, the contractions will be more continuous and even additive.

Continuous stimuli reactivate muscle contraction once the action potential cycle is complete.

Explanation:

Muscle contractions can be continuous or cumulative once the action potential curve drops, since the action potential at the top of the mountain is in a refractory period.

I knit a graph of what cumulative contractions are like due to continuous stimulation.

In the graph I leave you pointed out some references:

mr = refractory moment

mnr = non-refractory moment (where the new stimulation is accepted and a more powerful cumulative muscle contraction is generated)

PA = potential for muscle action or contraction itself.

Michael, a new lab analyst, receives an email notifying him that his expected samples from a recent outbreak should be arriving soon. To prepare for his analysis, he decides to look into what type of diseases could be spread between animals and humans, as this is a new field for him. Michael has received limited information about the details of the outbreak from the epidemiologists that traveled to the site, but he does know that both animals and humans were infected by some type of virus. Michael looks through some of the lab manuals on how the samples will be handled once in the lab. While reading through these guidelines, he realizes that there are some terms he is not quite sure of. Below are sentences that reflect the terms that Michael had to acquaint himself with while reading through the published guidelines from his laboratory.
Please review the sentences below and fill in the blanks with the correct word(s).
A. arthropods
B. togaviruses
C. encephalitis
D. flaviviruses
E. zoonosis
1. A virus that is able to be transmitted via________ like ticks, flies, and mosquitoes is considered a(n)_______
2. Some arboviruses are able to move through the bloodstream and infect the brains of humans and arbovirus animals. This disease manifestation is called_________
3. A________ is a disease that can be transmitted from animals to humans.
4. Several encephalopathies, such as Eastern equine encephalitis and West Nile virus encephalitis, are caused by the_______ animals such as horses and birds. These viruses can infect humans and animals

Answers

1.A arthropods

2.C encephalitis

3.E zoonosis

4.C togaviruses

All of the following would be visible on a karyotype except
aneuploidy.
polysomy.
trisomy.
homologous chromosomes.

Answers

Answer: I think aneuploidy id wait for someone else to confirm this

Explanation:

All of the following would be visible on a karyotype except is aneuploidy

How to identify karyotype?

The normal karyotype of the species is described as 46, may XX or XY, in which the first number of chromosomes is followed by a comma indicating the  chromosomes. Thus, 46, XX corresponds to the karyotype of a woman; and 46, XY represents a male karyotype.

Aneuploidy is the presence of an abnormal number of chromosomes in a cell so this is the exception.

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Which feature separates humans from other primates? smaller brain size bipedalism use of tools complex social skills

Answers

Answer:

Bipedalism.

Explanation:

Bipedalism is a human's ability in which they can use their two hind legs to run or walk without the help of their front limbs, unlike other primates.

Answer:

Bipedalism

Explanation:

i took the test and failed

(5 points)
The organ responsible for filtering up to 95% of th
maintaining body pH is the
pancreas.
urethra.
kidney.
A pancreas
B urethra
C kidney
D gall bladder

Answers

Answer:

C. Kidney

Explanation:

The kidney is a vital organ in the human body. It is bean shaped and helps in the filtration of toxic substances and wastes from the body fluids which is then reabsorbed into the bloodstream.

The kidney also controls the level of water, pH and sodium levels. It however controls the blood pH by excretion of hydrogen ions and forming bicarbonate which ensures the blood pH is within its optimal and normal range.

Answer:

kidneys

Explanation:

The kidneys are the body's filtration system, and are responsible for filtering out the fluids in the body. The biproduct of this is called urine and is removed from the body

help asap plss giving branlist

Answers

Answer:

Parasitic Relationship

Explanation:

Symbiotic relationship:

is a term that defines an interaction between organisms of different organisms.

Parasitic Relationship:

A relationship in which one organism is benefited and one is not.

Example: A tapeworm living at the gastrointestinal parts.

Mutualistic Relationship:

A relationship in which both organisms benefit.

Example: Egyptian plover bird and the crocodile.

Commensal Relationship:

A relationship in which both organisms are not benefited nor harmed.

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21. Evidence in support of the importance of endosymbiosis in the evolution of
eukaryotic cells is:
a, Organelles that have their own unique unique DNA and ribosomes
Organelles that have a double membrane
6. Organelles are in the same size range as free living prokaryotes
d. All of the above

Answers

Answer:

d. All of the above

Explanation:

The theory of endosymbiosis is important as it explains the evolution of  eukaryotic cells from prokaryotic cells.

This theory also explains the origin of chloroplast and mitochondria. Several evidences in support of the importance of endosymbiosis in the evolution of  eukaryotic cells are as following:

Organelles have their own separate DNA and ribososme.Organelles that have a double membrane  (inner and outer).Organelles are in the same size range as free-living prokaryotes.

Chloroplast and mitochondria are the examples of such organelles.

Hence, the correct answer is "d".

explain why a father with blood group AB cannot donate for a child with blood group O when he marries a woman with blood group O​

Answers

The odds are astronomical for a father with AB(IV) to have an O(I) child. The only possible way for this phenomenon to occur is if there was a nondisjunction in the ovogenesis for the 9th chromosome and the father also had a nondisjunction for the same chromosome(A sperm cell with no 9th chromosome fertilized an ovum with two 9 chromosomes).

A person with AB cannot donate to a person with O because the receiver has antibodies(alpha and beta) that bind to the antigens on the AB blood cells, causing death.

Why are the polychaete worms living near the underwater volcanic vent called Pompeii worms?

Answers

Because of the volcanic eruption of pompeii

The polychaete worms living near the underwater volcanic vent are called Pompeii worms because they look like the ancient Roman city of Pompeii and because they are the most heat-tolerant animals on Earth.

What is the significance of polycheata?

Polychaetes are found in many parts of the world and play many important roles in the environment, such as their importance in marine and freshwater ecosystems. They also have a rich fossil record, which helps scientists study evolution, polychaetes are commonly used as model organisms in biological research, and polychaetes are studied to clean up contaminated environments through bioremediation.

Hence, the polychaete worms living near the underwater volcanic vent are called Pompeii worms because they look like the ancient Roman city of Pompeii and because they are the most heat-tolerant animals on Earth.

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Through which vascular tissue do water and nutrients get transported to reach the leaves during transpiration? cuticle parenchyma xylem phloem

Answers

Answer:

Xylem is one of the two types of transport tissue in vascular plants, phloem being the other. The basic function of xylem is to transport water from roots to stems and leaves, but it also transports nutrients.

Explanation:

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Answer:

C. xylem

Explanation:

i tack test

2 Diseases of a cassava

Answers

The overall outcome of the activities carried out under the CaCESA initiative

will improve cassava production and productivity. The effectiveness of

program is based on five axes:

- provision of healthy cassava cuttings to vulnerable families;

- the organization of extensive awareness and communication campaigns;

- national and regional coordination of actors in the production chain and

cassava post-production;

- the improvement of cultivation, processing and conservation practices

cassava;

- control and management of the spread of diseases, whether they are transmitted

insects and / or infected cassava cuttings.

To achieve these results, it will be necessary to build capacity at different

levels. The objectives will be achieved through the implementation of appropriate activities

Explanation:

Answer:

Explanation:

Oidium manihotis

Root Rot Pathogens

Where is the last storage location for melted snow? (2 points) Where is the last storage location for melted snow? (2 points) Group of answer choices Rivers Ocean Streams Mountains

Answers

Answer:

Ocean

Explanation:

Ice is usually found in the glaciers in the mountains and once it gets heated it flows down through melting and forms a stream and enters into rivers and these streams combine and lead to the oceans. Thus these oceans become the ultimate storage units of melted snow. Ice and cannot stay in solid-state for too long.

Classify the following organisms into their respective kingdoms (i) Yeast (ii) Penicillium (iii) Rhizobium (iv) Mushroom (v) Amoeba (vi) fish

Answers

Answer:

(i) Yeast- Kingdom Fungi

(ii) Penicillium- Kingdom Fungi

(iii) Rhizobium- Kingdom Eubacteria

(iv) Mushroom- Kingdom Fungi

(v) Amoeba- Kingdom Protista

(vi) fish- Kingdom Animalia

Explanation:

Living organisms were classified into a large group called KINGDOM, which represent the largest and most generic grouping consisting of organisms that share a few similarities. The kingdoms that living organisms were classified into are as follows: Plantae, Animalia, Fungi, Protista, Eubacteria, Archaebacteria, etc.

Based on the question, the mentioned organisms are classified into the following kingdoms:

(I) Yeast: Yeast is a unicellular microbe classified under the Kingdom Fungi due to possession of chitin in its cell wall and other similar features with members of kingdom Fungi.

ii) Penicillium- Penicillium is a genus classified under the Kingdom Fungi.

(iii) Rhizobium- Rhizobium is a genus of prokaryotic organism (lack membrane-bound nucleus and organnelles) classified under the Kingdom Eubacteria.

(iv) Mushroom- Mushrooms are saprophytic (heterotrophic) species of organisms classified under the Kingdom Fungi.

(v) Amoeba- Amoeba is a genus of unicellular eukaryotes classified under the Kingdom Protista.

(vi) fish- Fishes are organisms classified under the Kingdom Animalia

Human activities, including the use of fossil fuels, have contributed to global
warming and the rise in sea levels. Both of these environmental changes are
threatening ecosystems and human communities worldwide. How could
scientists best cooperate to use scientific research to mitigate this problem?
A. They could look at trends in climate change to predict regions of
concern.
B. They could set regulations in their own countries to protect local
resources.
C. They could make personal choices that help reduce their carbon
footprints.
D. They could study climate change on other planets to predict its
effects on Earth.

Answers

Answer:

1 C when carbon footprint are reduced

It will reduce the rate of global warming

They could make personal choices that help reduce their carbon

footprints.

A carbon footprint is the total amount of greenhouse gases including carbon dioxide and methane that are generated by  actions.

What is carbon footprint?Carbon footprint, amount of carbon dioxide emissions associated with all the activities of a person or other entity like building. It includes

                 - Direct emissions, such as those that result from fossil-fuel.

                 - Heating and transportation.

                 - Emissions required to produce the electricity.

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Which of these is an example of a haploid cell?

Answers

Answer:

Gametes

Explanation:

Gametes are an example of a haploid cell and are produced as a result of meiosis.

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The first entry of the resulting matrix is: why is know app downloading in my android phone even if I have 900 MB ??? Match the detailed statements from the passage with the major points they best support. How did the Commercial Revolution contribute to the start of the IndustrialRevolution in Great Britain?A. It encouraged British leaders to devote their attention to Britainitself rather than focusing on the resources of British colonies.B. It forced millions of British workers to leave farms and seekemployment in urban factories.C. It helped British industries end their reliance on coal power infavor of steam power.D. It allowed British companies to easily secure capital and ship theirproducts overseas. Consider the two functions. Which statement is true?A)Function 1 has a greater rate of change by 13/4B)Function 2 has a greater rate of change by 13/4C)Function 1 has a greater rate of change by 13/2D)Function 2 has a greater rate of change by 13/2 Please help!!!!! science, please explain in sentence cause yes i dont know where to find these answers ! 18. In a recent survey, 75% of the community favored building a police substation in their neighborhood. If 10 citizens are chosen, find the probability that exactly 8 of them favor the building of the police substation. Complete in the blank with the correct Indirect object pronoun: Me, TE,LE,NOS, OS, LES. 1) Juan _______ da ina Camisa a el, su mejor amigo. 2) Maria ______ da unos libros a nosotros. 3) Nosotros ______ la cocinamos a Ella 4) Nosotros ______ lo cocinamos a ti. 5) Pedro ______ lo prepara a mi primary care practitioners provide which type of carea) hospital care and surgical supervisionb) diagnosis and treatment of complex conditions c) laboratory testing and imagine procedured) preventative care and treatment of routine aliments URGENT!!! Please help me with this question!!! Why did Congress impeach President Andrew Johnson in 1868? Sudoku Company issues 7,000 shares of $7 par value common stock in exchange for land and a building. The land is valued at $45,000 and the building at $85,000. Prepare the journal entry to record issuance of the stock in exchange for the land and building. Zack is a high school student with a speech disorder. Which one of the following characteristics is least likely to be associated with his disability?A. Zack sometimes says sentences with the words in an atypical order. B. Zack's reading skills are among the lowest in his class. C. When asked to speak in front of a group, Zack blushes and looks uncomfortable. D. Zack has difficulty with writing assignments. Graph f(x) = \xi.Click on the graph until the graph of f(x) = \xi appears. what is the rational exponent from of this expression Some Texans lost their jobs when NAFTA went into effect.- True-False The balanced scorecard approach relies not only on financial performance measures, but includes customers, internal business processes, and organizational learning and growth.a. Trueb. False Clarisse wants to start a moderate cardiorespiratory endurance exercise program, but she has been sedentary for the past 5 years. Which of the following activities would be the best for her to incorporate to meet her goal of increasing her cardiorespiratory endurance?a. Water aerobicsb. Cardiorespiratory endurancec. At least 150 minutes of moderate intensity aerobic activity per week. Use the following information for Jett Co. to answer the following question: 2015 2014 Sales 1,200 1,000 COGS 850 700 Operating Expenses 200 200 Income Taxes 30 35 Jett Co.'s average tax rates for 2015 and 2014 are: A. 15.5% and 10.0% B. 20.0% and 35.0% C. 25.8% and 35.4%. D. 31.4% and 36.8%. Bella is going back to school shopping and her favorite store is having a sale. She sees there are 4 packages of 15 tops for $18 and 5 packages of 10 tops for $16 which is the better deal? How do you know