Being able to understand the relationship between DNA, mRNA, tRNA, ribosomes and proteins, is necessary for any researcher interested in gene therapy. Gene therapy is dedicated to correcting genetic defects by replacing mutated genes with wildtype versions. This can include complete removal and replacement of the entire gene (knock-outs or knock-ins) or removal of only the actual mutated nucleotides. Sickle Cell Disease is an example of a single-point mutation: GAG becomes GTG, which codes for a new amino acid. One would only need to replace a single base to correct the disorder making it very amenable to gene therapy. The mutant sickle cell allele is called HbS (for sickled hemoglobin) while the wt allele is HbA. Philippe Kasongo, a masters student from Oxford is studying for an oral exam on gene therapy, and has an especial interest in the disorder since he comes from the Democratic Republic of Congo where Sickle Cell has a historical high rate of occurrence due to the prevalence of malaria. Oral exams are a feature of certain British schools where students form a line and have to answer a series of questions from their proctor rather than take a written exam. Should we try oral exams at Lehman this semester

Answers

Answer 1

Answer:

Yes.

Explanation:

Yes, we should try oral exams at Lehman this semester in order to fulfill the research on gene therapy done by the masters student. Test is to evaluate the performance of the student in the class, it can be taken by both the methods i.e. through written or through oral exams. Both have the same significance because both evaluate the performance of the students so we can try oral exams instead of written exams at Lehman this semester to help the masters student in his research.


Related Questions

What is better for a beginners pet leopard gecko or crested gecko

Answers

Answer:

leopard gecko

Explanation:

Answer:

you chose based off what i type

Explanation:

crested geckos need a vivarium and a uvb light but turn it off at night cause they are nocturnal they need stuff to climb on a hide and a clean cage the eat a powder mixed with water and crickets you can give them other bugs to they can jump from your hand to your arm if they want to they will drop there tail if scared they do not grow back also super cute

leopard geckos need a 20 gallon or bigger terrarium with uvb to turn off at night and a heat pad 24\7 make sure its no to hot leopard geckos need a variety of bugs like crickets and bubia roaches and other  and a clean tank and at least 2 hides they will drop there tail but they do grow back they just look a little different but are super cute

What can you tell about bacteria that have been Gram stained?
A) Microscopic morphology
B) Macroscopic morphology
C) Gram reaction
D) A and C

Answers

Answer:

D) A and C

Explanation:

Gram staining is a laboratory technique used for bacterial species. It is used to differentiate between two groups of bacteria based on the components of their cell wall. Gram staining was developed by a scientist called Christian Gram in the year 1884. In the gram stain procedure, the following occurs:

- Due to the thick peptidoglycan component of their cell wall, GRAM POSITIVE bacteria retains the crystal violet due and stain VIOLET.

- On the contrary, due to the thin peptidoglycan component of their cell wall, GRAM NEGATIVE bacteria do not retain the crystal violet dye and hence stain, RED.

Based on this, a bacteria that has been gram stained has been tested for its GRAM REACTION and microscopic morphological characteristics, since it is a microbe.

If you throw a rock into the air, its instantaneous speed is probably highest
A) at the top of its flight
B) halfway to the top of its flight
C) when you throw it and right before it hits the ground
D) when you throw it
E) right before it hits the ground​

Answers

Answer:

B halfway to the top of it's flight

D or B

Explanation:

I don’t know how to explain it.. sorry

Complete the following statement from what you have learned about the motor unit. In some neurodegenerative diseases the lower motor neuron cell bodies die and the remaining lower motor neurons sprout processes that innervate the neuromuscular synapses vacated by the dead lower motor neurons. In these muscles, the size of the motor unit ____________ and the strength of the muscle contraction generated by individually activating each surviving motor neuron _________.

Answers

Answer:

The correct answer is - increase, increase.

Explanation:

In some neurodegenerative diseases, some lower motor neuron cells die and the remaining lower motor neurons continuing the process of the vacated dead motor neuron cells to innervate the neuron and muscle synapses.

The size of the motor unit increases and due to the innervations of the new axon

increases the strength of the muscle contraction occurred by individually activating each surviving motor neuron. Here multiple motor units will be controlled by a single neuron.

Tina used 500 N of force to move a desk. The desk weighed 300 N, and she
moved it 1.5 meters. How do you calculate the work done by Tina?
A. Multiply 300 by 1.5.
B. Add 500 to 300.
O
C. Multiply 500 by 1.5.
D. Divide 300 by 1.5.

Answers

Answer:

The correct answer is - C. Multiply 500 by 1.5.

Explanation:

Given:

Force to move a desk = 500 N

weight of desk = 300 N

displacement = 1.5 meters

work done by Tine = ?

Formula:

work done (W) = F*d

where F is the force applied on the desk and d is the displacement of the desk.

Solution:

As the displacement is perpendicular to the weight of the desk, therefore, the work done by weight is zero. The work done to the displacement of the desk would be =

W = F*d

= 500*1.5

= 750 J

Thus, the correct answer would be option C.

What is the relationship between recombination frequency and location of genes on a chromosome?

Answers

Answer:

hi

Explanation:

In a DNA molecule, G pairs with __

Answers

Answer:

cytosine

Explanation:

Guanine is one of the building blocks of DNA. It's the G in the A, C, G, or T. Guanine in the double helix pairs with cytosine, so you will see CG pairs; one on one strand and one on the other.

Answer:

In a DNA molecule, G pairs with C

Explanation:

Wish you luck! Have a good day~

1. How do plants get the raw materials for photosynthesis?

Answers

Answer:

they absorb water and minerals from the soil and use the energy of the sun to synthesize sugars (carbohydrates)

Consider a plant with the following characteristics. Round leaves (R) are dominant to pointed leaves (r). White flowers (W) are dominant to pink flowers (w). Plants heterozygous for both traits are crossed. What is the probability of obtaining a plant with pointed leaves and pink flowers

Answers

Answer:

.0625 or 6.25%

Explanation:

Find the probability for the plant to have pointed leaves. If the two parent plants are heterzygous, then the likelihood the plant has a recessive characteristic is 25%, 1/4, or .25 for our calculations.Find the probability for the plant to be pink. If the two parent plants are heterzygous, the likelihood the plant has another recessive characterisitc is again 25%, 1/4, or .25 for our calculations.Multiply them together. (1/4)*(1/4)=(1/16) or .0625, or 6.25%

Arrange the terms in the correct order:
tissue, organism, organ, cell, system​

Answers

Answer:

cell, tissue, organ, system​, organism

Explanation:

1. The Earth experiences days and nights due to the:


a. revolution around the sun.


b. tilt of Earth.


c. rotation on it's axis.


Choose the correct answer not cutt

Answers

Answer:

c. rotation on it's axis

What is the official language of Peru?
Portuguese
Spanish
Dutch
English

Answers

Answer:

Spanish

Explanation:

Your answer is Spanish. Have a good day

Something you might call someone who is small invertebrates animals

Answers

The rotifer, or wheel animal, which can be as small 50um.

Using the template, construct an appropriately labeled graph to represent the data in Table 1. Based on the data, determine the antimalarial drugs that are likely to be significantly less effective at treating disease caused by the ART-R strain than by the ART-S strain.

Answers

Answer:

Explanation:

The first one got messed up but its 130

modern scientific explanations of evolution
a. have replaced darwin’s thinking
b. combine the principles of natural selection and genetic inheritance
c. rely on genetics instead of natural selection
d. fail to explain how traits are inherited

Answers

C is the answer hope it’s right

In cats, some are black, some are orange, and some are calico (fur that is both black and orange) All calico cats are always females. This trait represents two inheritance patterns. This two and explain how you know.

please help.

Answers

Calico cats are predominantly female because they’re colouring is related to the X chromosome.

Two X chromosomes are needed for a cat to have that distinctive tri-colour coat.If a cat has an XX pair, she will be female.Male cats have an XY chromosome pair, so they can’t be Calicos.

Have a great day <3  (I love cats)

Answer: In cats, one of several genes controlling fur color is located on the X chromosome. The gene has two versions, or alleles. One form of the gene codes for orange fur (XB), and the other form codes for black fur (Xb). While it's difficult to say which allele is dominant and which is recessive, since only one is ever expressed (see below), let's say, for the sake of argument, that orange is dominant to black. Ordinarily, this would mean that an animal inheriting one copy of each gene (genotype XBXb) should have orange fur. Surprisingly, a female cat heterozygous at that locus (XBXb) will not be orange. Instead, her coat will be a patchwork of orange and black, a condition known as tortoiseshell. Male color expression is straightforward. Because only one allele exists for the gene in each cell, it will be expressed. And all males have only B or only b. There are no heterozygotes, because the Y does not carry the allele.

Explanation:

I got this from an article! I hope this helps.

Higher forms of life such as humans and other mammals generally reproduce-

A-by both sexual and asexual reproduction
B-only sexually
C-only asexually ​

Answers

Answer:

B- only sexually

Explanation:

Higher forms of life generally reproduce sexually in order to increase the amount of genetic variation within their population. I hope this helps!

Each of the following statements describes a step in the replication of SARS-CoV-2. These steps are listed in random order. Read through the steps and, in the spaces provided below, list them in the order they occur in the human body.
- The virus releases its RNA genome into the cell.
- Viral RNA polymerase helps transcribe more copies of the virus’s RNA.
- The virus binds to a receptor on a human cell’s membrane.
- New viruses travel to the cell membrane of the infected cell and are released outside the cell.
- The virus’s RNA is translated into proteins by the cell’s ribosomes.

Answers

Answer:

- The virus binds to a receptor on a human cell’s membrane.

- The virus releases its RNA genome into the cell.

- The virus’s RNA is translated into proteins by the cell’s ribosomes.

- Viral RNA polymerase helps transcribe more copies of the virus’s RNA.

- New viruses travel to the cell membrane of the infected cell and are released outside the cell.

Explanation:

Coronaviruses are viruses from the family Coronaviridae (Order Nidovirales), which are structurally composed of positive-sense single-stranded RNA (ssRNA) genomes with a size of approximately 25 to 33 kilobases. Since the coronavirus genome consists of an ssRNA, they can be directly translated into protein inside infected host cells. The coronavirus that has caused the recent pandemic can enter into host cells through its spike (S) glycoprotein which binds to the Angiotensin-converting enzyme 2 (ACE2) receptor. Subsequently, this virus exploits the host molecular machinery to encode an RNA polymerase which is used to generate RNA from an RNA template. Finally, these RNAs are translated into all viral components (structural proteins) and new viruses are recruited to infected cells.

Pretty please help!!!
what would happen if scientific knowledge was not adaptable​

Answers

there where no more correct solutions, they would be wrong, since the scientific method establishes relationships between facts, where it is a useful application for man.

Which of these events occurs first during the process of transcription?
A. RNA polymerase joins nucleotides into the RNA molecule.
B. RNA polymerase binds to the promoter.
C. Introns are removed from the RNA molecule.
D. Exons are removed from the RNA molecule.

Answers

Answer:

B. RNA polymerase binds to the promoter.

helppppppppppp meeeeeeee​

Answers

The answer is flow of energy

Every time a monkey is fed, a buzzer sounds. The monkey will probably. OA. think it will be fed when it hears a buzzer O B. become thirsty when it hears a buzzer O C. think it is full when it hears a buzzer OD. stop eating whenever it hears a buzzer​

Answers

Answer:

I think D because now the monkey is distracted by the buzzer

Consider a cross between a plant with two flower colors, yellow and red. Yellow (Y) exhibits complete dominance over red (y). It also has either single blossoms or double blossoms, single blossoms (S) exhibit complete dominance over double blossoms (s). A dihybrid yellow, single blossomed flower is crossed with a red flowered and double blossomed plant. You observe the following phenotype frequencies among the 1545 offspring plants:
500 yellow flowers and single blossom plants
515 red flowers and double blossom plants
260 yellow flowers and double blossom plants 270 red flower and single blossom plants.
What is the recombination frequency between these two genes?
a. (260+270) 1545
b. 270/1545
c. 1545/ (260+270)
d. 260/1545
e. (500+515)/1545
f. 1545/260
g. 1545/270
From these results one can conclude that:_______.
a. the two genes are linked
b. the two genes are not linked
c. if the genes are linked, they are separated far enough apart to appear to assort independently

Answers

Answer:

1) option a is correct. (260+270)/1545

(Note about this option: In the statement, it is written as (260+270) 1545. Lacks the division symbol, / )

2) From these results one can conclude that the two genes are linked (option a)

Explanation:

To know if two genes are linked, we must observe the progeny distribution. If heterozygous individuals, whose genes assort independently, are test crossed, they produce a progeny with equal phenotypic frequencies 1:1:1:1. If we observe a different distribution, phenotypes appearing in different proportions, we can assume linked genes in the double heterozygote parent.  

We might verify which are the recombinant gametes produced by the di-hybrid, and we will be able to recognize them by looking at the phenotypes with lower frequencies in the progeny. Phenotypes with the highest frequencies represent the parental gametes.

To calculate the recombination frequency, we will use the following formula: P = Recombinant number / Total of individuals.  

In the present example:

Parental)        YySs                        x                 yyss

Gametes)  YS parental type                        ys, ys, ys, ys

                 ys parental type

                 Ys recombinant type

                 yS recombinante type

The total number of individuals in the offspring: 1545

Phenotypic class Number of offspring  

500 Y-S- (parental)515 yyss (parental)260 Y-ss (recombinant)270 yyS- (recombinant)

According to this information, the phenotypic frequencies of the progeny differ from the phenotypic ratio 1:1:1:1. We can assume then, that these genes are linked.

The recombination frequency is:

P = Recombinant number / Total of individuals

P = 260 + 270 / 1545

P = 530/1545

P = 0.343

The genetic distance between genes is 0.343 x 100= 34.4 MU.

Which molecule carries the protein code from the nucleus so translation can occur?

Answers

Answer:

messenger RNA

Explanation:

The type of RNA that contains the information for making a protein is called messenger RNA (mRNA) because it carries the information, or message, from the DNA out of the nucleus into the cytoplasm. Translation, the second step in getting from a gene to a protein, takes place in the cytoplasm

can someone pls help :)

Answers

Answer:

1 . A 3.B 2 .B . this is all I know but try the internet for more

Down syndrome in humans may result from. A a person inheriting a recessive allele. B sickle-shaped cells becoming stuck in blood vessels.c an extra copy of chromosome 21. D blood failing to clot properly.

Answers

C born with an extra chromosome

Side-chain hydrogen bonding :__________
a) Side chains that can form hydrogen bonds are located on the outside of a protein, where they can stabilize tertiary structure by forming hydrogen bonds with water.
b) Two cysteine residues can form hydrogen bonds.
c) Side chains connect distant parts of a polypeptide chain and introduce loops into the chain.
d) Threonine and glutamine can form hydrogen bonds.
e) Hydrogen bonds stabilize quaternary protein structure by holding together several protein strands.

Answers

Answer:

a) Side chains that can form hydrogen bonds are located on the outside of a protein, where they can stabilize tertiary structure by forming hydrogen bonds with water.

Explanation:

A hydrogen bond occurs between a hydrogen atom and four other elements. The side chain hydrogen bonds are resulted from the tertiary arrangement of structural components of the proteins.

The side chain hydrogen bond are present at the outside of the protein at places where the water forming the hydrogen bond can stabilize the tertiary structure.

help l m a o ........​

Answers

Answer:

D

Explanation:

LKM iF i AM CORRECT

ESP: actuan las hormonas solo sobre celulas o pueden actuar sobre otras estructuras?

ENG: do hormones act only on cells or can they act on other structures?

Answers

Answer:

Hormones act only on cells not structures.

Explanation:

Hormones act only on cells and they  do not act on other structures because there are specific cells have receptors for that particular hormone. Some hormones bind itself to the receptors on the surface of target cells whereas other hormones enter the cells and bind itself to the receptors present in the cytoplasm or nucleus of the cell.

what comes first mieosis or mitosis​

Answers

Answer:

I'm not sure there's a first exactly, but if I had to guess I'd say mitosis.

Explanation:

Meiosis produces genetically identical cells, results in diploid cells and takes place throughout an organism's lifetime; involved in asexual reproduction. Meiosis produces genetically unique cells, results in haploid cells, only happens at curtain times in an organism's life cycle; involved in sexual reproduction.

Meioseis the first

In the first division the homologous chromosomes are separated, in the second the sister chromatids. That is to say: meiosis consists of two consecutive divisions between which the DNA does not replicate. These two divisions are called mitosis or division I and mitosis or division II of meiosis.
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