AZT is a drug that is commonly used to fight HIV infection. The active component of AZT is a nitrogenous base that mimics thymine. Normal nucleotides CANNOT covalently bond to the thymine mimic. HIV's reverse transcriptase enzyme will use the thymine mimic instead of using thymine, whereas our DNA polymerase will not make this mistake. What is the most likely explanation for how AZT prevents HIV replication

Answers

Answer 1
Answer:

AZT works by selectively inhibiting HIV's reverse transcriptase, the enzyme that the virus uses to make a DNA copy of its RNA. Reverse transcription is necessary for production of HIV's double-stranded DNA, which would be subsequently integrated into the genetic material of the infected cell to produce its proteins. All reverse transcriptase inhibitors are analogues of the naturally occurring deoxynucleotides needed to synthesize the viral DNA and they compete with the natural deoxynucleotides for incorporation into the growing viral DNA chain.


Related Questions

what are the chances that a color blind man will have a color blind grandson what are the genotypes for all involved.

Answers

Answer:

Depends

Explanation:

It depends if the genotypes are hetero.zygous or resessive/dominant homo.zygous. Being colorblind could be represented by a resessive genotype like, bb. if their son/daughter has Bb or bb or their son/daughter in law has a resessive trait then having a color blind grandchild maybe possible. The colorblind grandson has parents that both have at least 1 resessive trait, then the grandson could not be colorblind.

The type of evolution that produced species P and H from species B:

A. divergent evolution
B. sequential evolution
C. phyletic gradualism
D. punctuated equilibrium

Answers

is Cccc grrrr ok bhshwaiiwhwvdvdve

Directions Make a list of objects, products, and any other items around your house where plants were involved in the production of the item. You should have a list of at least twenty items. Then respond to the following questions: Note: Your list of objects and the answers following should be at least 200 words in length. What if plants no longer existed on Earth? How would your life be different?

Answers

Answer:

-20 items-

Bed

Cat

Dog

desk

water

stove

oven

chair

toilet

shirt

shampoo

shoes

backpack

food

socks

paper

pencil

table

mask

towel

If Plants no longer existed on earth then there would be no way for carbon dioxide to be converted into oxygen, without oxygen animals and humans alike would die. The Worlds "Air" would be toxic for us to breathe, we need plants to survive. Without plants, animals would die of starvation, and predators would as well without substance.

What characteristic could provide a species with a better chance of surviving a drastic environmental change?

(A) A small population size

(B) A highly diversified gene pool

(C) specialized cells within the body

(D) Many individuals with the recessive trait

Answers

the answer is B


Species with a limited variety of phenotypes and where all members of the species are similar to one another have a smaller chance of coping with environmental variability compared to a species with greater diversity.

A highly diversified gene pool could provide a species with a better chance of surviving a drastic environmental change. So, the correct option is B.

What is Diversified Gene pool?

Greater genetic diversity within a population is made possible by a diverse gene pool, which raises the possibility that at least some members of the population will exhibit features that are more adapted to the new environment.

This variety can develop as a result of gene flow from other populations or mutations. The number of people having the recessive trait or a limited population size, however, would not always give an advantage in enduring environmental change. A species may have a better chance of surviving a severe environmental shift if its gene pool is extremely varied.

Therefore, the correct option is B.

Learn more about Gene pool, here:

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Which of the following conditions would activate the unfolded protein response? (check all that apply)
Group of answer choices
a. reduction in receptor-mediated endocytosis
b. synthesis of many extra secreted proteins.
c. mutation of a factor critical for degradation of proteins in the lysosome
d. mutation of a factor important for protein folding in the ER

Answers

Answer:

b. synthesis of many extra secreted proteins.

c. mutation of a factor critical for degradation of proteins in the lysosome

d. mutation of a factor important for protein folding in the ER

The conditions that would activate the unfolded protein response are:

Synthesis of many extra secreted proteins.Mutation of a factor critical for degradation of proteins in the lysosome.Mutation of a factor important for protein folding in the ER.

What do you mean by unfolded protein response?

The unfolded protein response may be defined as a cellular stress response related to the endoplasmic reticulum stress. It is a mechanism through which the accumulation of misfolded protein is induced.

Unfolded protein response gats are activated when there is any mutation or alteration that takes place in the ER, and sometimes lysosomes. Because these are both organelles that mediate the protein trafficking throughout the cell.

Therefore, the conditions that would activate the unfolded protein response are statements (b), (c), and (d).

To learn more about Unfolded protein response, refer to the link:

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The first unstable compound formed during C3 cycle is:
(a) 3-carboxy,2-keto, 1,6 bi phosphorobitol
(c) 2-carboxy,3-keto,1,5 biphosphorobitol
(b) 2-carboxy,3-keto,1,5-biphosphorobitol
(d) 3-carboxy,3-keto, 1,6-biphosphorobitol​

Answers

Answer:

(b) 2-carboxy,3-keto,1,5-biphosphorobitol

Explanation:

2-carboxy, 3-keto, 1,5-biphosphorobitol is the first unstable molecule formed during the C3 cycle. Due to its instability, this molecule is quickly broken down into two molecules each containing 3 carbon atoms, called 3-phosphoglyceric acid, this breakdown is done through water in a process known as hydrolysis.

help pleaseee

give an example of lamarcks theory of evolution:

Answers

Lamarck believed that elephants all used to have short trunks. When there was no food or water that they could reach with their short trunks, they stretched their trunks to reach the water and branches, and their offspring inherited long trunks.

5. Which of the following statements is correct?

-Reabsorption of water is hormonally controlled
-Normal filtrate contains large amounts of protein
-Most of the water passing through the kidney is eliminated as urine
-The excretion of sodium ions is one of the mechanism that maintains pH balance in the blood.

Answers

Answer:

most of water passing through through the kidney is eliminated as urine

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