An investigator proposes a study to determine the clinical relevance of a new assay technique to measure minimal residual disease (MRD) in adolescent (age 14-16) cancer patients undergoing chemotherapy. The study requires that two additional bone marrow aspirates be performed during the course of chemotherapy. The subject's chemotherapy will not be altered based on the results of the assay technique measures. However, future patients with cancer would benefit from improved interventions based on study findings. The IRB determined that the activity was a minor increase over minimal risk. Which of the following statements best describes the IRB approval requirements for involving adolescent cancer patients in the research study?

Assent is not required, however, both parents must give permission for the inclusion of the adolescent child.
Assent of the child only is required.
Assent is not required, however, one parent must give permission for the inclusion of the adolescent in this study.
Assent of the child and permission of both parents are required.

Answers

Answer 1

The correct answer is D. Assent of the child and permission of both parents are required.

Explanation:

In any research study, it is required to ask for the assent of the participants, no matter if the risk is low, which is established by the Institutional Review Board or IRB that regulates ethics in research. This implies in the case presented, the assent of the child is necessary, especially because a medical procedure (additional bone marrow aspirates) will be performed, and this is related to risks.

Besides this, if the participant is a minor the permission of both parents or the legal is needed as the child might not have the maturity to decide whether to participate in the research study. Thus, the requirements are " Assent of the child and permission of both parents are required".


Related Questions

The standard reduction potential of a chromium electrode is -0.74 volts when chromium is reduced from chromium (III). The standard potential of the cell where chromium is oxidized and cerium (IV) is reduced to cerium (III) is 2.35 V. For each half reaction how many electrons are transferred

Answers

Answer:

three electrons were transferred in the process

Explanation:

The electrode potential of the cathode is

E°cathode= E°cell + E°anode

E°cathode = 2.35V + (-0.74V)

E°cathode= 1.61 V

Let us look at the reduction half equation; the oxidation half equation must be;

Oxidation half equation;

Cr(s) ----> Cr^3+(aq) + 3e

The reduction half equation must now be

Reduction half equation;

3Ce^4+(aq) + 3e ----> 3Ce^3+(aq)

This implies that three electrons were transferred in the process as shown by the balanced half cell reaction equations.

example of nobel gas​

Answers

Answer:

helium , krypton,xenon,radon, argon are noble gasses

Helium Two examples would be helium and argon.

A scuba diver’s air tank contains oxygen, helium, and nitrogen at a total pressure of 205 atmospheres. The partial pressure of nitrogen is 143 atmospheres, and the partial pressure of helium is 41 atmospheres. What is the partial pressure of oxygen in the tank?

Answers

answer is 20

explanation: total Pressure = 205

partial pressure of N = 143

partial pressure of He = 41

total pressure = partial pressure of N + partial pressure of O + partial pressure of He

partial pressure of O = 205 - 185 = 20

Answer:

20

Explanation:

If he wants to model a longitudinal wave that carries more energy, how should he move the end of the spring?

Answers

Answer:

they won

Explanation:

Given isotope of nitrogen (N) contains 7 electrons, 7 protons and 8 neutrons. - What is the mass number - What is its atomic number

Answers

Answer:

Mass no= 16

and atomic no= 7

Explanation:

mass number is equals to number of protons + number of neutrons .

atomic number is equals to number of protons .

Consider the half reaction below.

Which statement best describes what is taking place?

Chlorine is losing electrons and being oxidized. Chlorine is losing electrons and being reduced. Chlorine is gaining electrons and being oxidized. Chlorine is gaining electrons and being reduced.

Answers

Answer:

balancing of charges of both sides

Answer:

A

Explanation:

A...............................

A student weighed out a sample of acid powder and found the mass to be 1.42 g. When the solution turned pink, the student read the burette accurately and found it to be 32.48 mL. If the base concentration is 0.1426 M, what is the molecular weight of the unknown acid

Answers

Answer:

306.6g/mol

Explanation:

To calculate molecular weight you need to know how many grams ou have in a determined amount of moles of substance. As you have the mass of the sample (1.42g), you need to find how many moles are, as follows:

The reaction of the acid HX with the base YOH is:

HX + YOH → H₂O + YX

1 mole of acid reacts per mole of base.

In a titration, the solution turned pink when moles base = moles acid.

Moles of base that the student added (Using the volume and molarity of the solution) are:

32.48mL = 0.03248L ₓ (0.1426 moles base / L) = 0.004632 moles of base

As the titration is in equivalence point, there are 0.004632 moles of the acid

Molecular weight (Ratio between grams of sample and its moles) is:

1.42g / 0.004632 moles =

306.6g/mol

Which type of graph is best used to show how a measured quantity changes over time?

Box and whisker plot
Line graph
Circle graph
Histogram

Answers

Line graph; shows relationship between an independent and dependent variable. One example of an independent variable is time.

Which of the outer planets is MOST like Earth? How?

Answers

Answer:

venus

Explanation:

hope i helped

brainliest pls pls pls

-Zylynn

Answer: I would say that Saturn is most like Earth. Not only does it have moons, like Earth, but the atmosphere is also denser like Earth. It also has windstorms, granite they are much more intense than Earth’s, but they do indeed happen. Saturn also has hydrogen gas; this gas is here on Earth supporting life in our ocean. Therefore, there is a chance that the conditions on Saturn could provide the essentials for there to be life.

A large scuba tank with a volume of 18 L is rated for a pressure of 220 bar. The tank is filled at 20 °C and contains enough air to supply 1860 L of air to a diver at a pressure of 2.37 atm (a depth of 45 feet). Was the tank filled to capacity at 20 °C?

Answers

Answer:

Yes, at 20 °C the tank was filled to full capacity

Explanation:

Given;

let initial pressure, P₁ = 2.37 atm

let initial volume, V₁ = 1860 L

let final pressure, P₂ = 220 bar = 217.123 atm

let final volume, V₂ = ?

Subject the air volume (1860 L )  at 2.37 atm to the tank rating (220 bar)

Ideal law is given by;

PV = nRT

At a fixed mole and gas temperature, the equation becomes;

P₁V₁ = P₂V₂

V₂ = (P₁V₁) / P₂

V₂ = (2.37 x 1860) / 217.123

V₂ = 20.3 L

After subjecting the air volume to tank rating, the volume of the air at 220 bar is 20.3 L which is greater than tank volume (18 L).

The extra 2.3 L can be assumed to be compressed gas volume due to the given (lower) temperature.

Thus, at 20 °C the tank was filled to full capacity.

[O.01]Which of these is the location where sea floor spreading occurs? abyss guyot ocean trenches mid-ocean ridges

Answers

Answer:

D. mid-ocean ridges

Explanation:

The location where seafloor spreading occurs is at mid-ocean ridges. Therefore option 4 is correct.

Mid-ocean ridges are underwater mountain ranges that extend through the Earth's oceans. They are formed by the tectonic plates diverging or moving apart from each other.

As the plates separate, magma rises from the mantle to fill the gap, creating new oceanic crust. The molten material solidifies to form new seafloor, which then moves away from the ridge in opposite directions.

Seafloor spreading is a key process in plate tectonics and the continuous renewal of the Earth's crust.

It leads to the expansion of the ocean basins and the formation of new crust, contributing to the overall movement and reshaping of the Earth's lithosphere.

Therefore, the correct answer is option 4: mid-ocean ridges.

Know more about mid-ocean ridges:

https://brainly.com/question/31194132

#SPJ2

PLEASE HELP ASAP The molecular weight of oxygen gas (O2) is 32 g/mol. What is the mass of a single oxygen atom? 2.66 x 10-23 g 3.13 x 10-1 g 1.06 x 10-23 g 5.31 x 10-23 g

Answers

Answer:

5.31×10¯²³ g.

Explanation:

Data obtained from the question include:

Molar weight of O2 = 32 g/mol

Mass of 1 oxygen atom =..?

From Avogadro's hypothesis, we understood that 1 mole of any substance contains 6.02×10²³ atoms.

This implies that 1 mole of O2 also contains 6.02×10²³ atoms.

1 mole of O2 = 32 g

The mass of 1 atom of O2 can be obtained as follow:

32 g of O2 contains 6.02×10²³ atoms.

Therefore Xg of O2 will contain 1 atom i.e

Xg of O2 = 32/6.02×10²³

Xg of O2 = 5.31×10¯²³ g

Therefore, the mass of a single oxygen atom is 5.31×10¯²³ g.

The mass of a single oxygen atom is 5.31 x 10⁻²³ grams. Therefore, option D is correct.

The molecular weight of oxygen gas is 32 g/mol. To find the mass of a single oxygen atom, divide the molecular weight by Avogadro's number (6.022 x 10²³ atoms/mol).

Avogadro's number (6.022 x 10²³) represents the number of particles (atoms, molecules, or ions) in one mole of a substance.

To find the mass of a single oxygen atom, divide the molecular weight of oxygen gas by Avogadro's number:

Mass of a single oxygen atom = (32 g/mol) / (6.022 x 10²³ atoms/mol)

Simplifying the expression:

Mass of a single oxygen atom = 5.31 x 10⁻²³ g

Therefore, the mass of a single oxygen atom is 5.31 x 10⁻²³ grams.

To learn more about the oxygen atom, follow the link:

https://brainly.com/question/12442489

#SPJ6

Consider a pure crystalline solid that is heated from absolute zero to a temperature above the boiling point of the liquid. Which of the following processes produces the greatest increase in the entropy of the substance?
a) melting the solid
b) heating the liquid
c) heating the gas
d) heating the solid

Answers

The question is incomplete, the complete question is;

Consider a pure crystalline solid that is heated from absolute zero to a temperature above the boiling point of the liquid. Which of the following processes produces the greatest increase in the entropy of the substance? A ) melting the solid B ) heating the gas C ) vaporizing the liquid D ) heating the solid E ) heating the liquid

Answer:

vaporizing the liquid

Explanation:

We generally define entropy in chemistry as the degree of disorderliness in a system. The entropy of gases is greater than that of liquids and the entropy of liquids is greater than that of solids. It then logically follows that the degree of entropy in gases is the greatest among all the states of matter while the entropy of solids is the least among all the states of matter since solid particles remain in their mean positions and can only vibrate or sometimes rotate. Liquid particles may translate while gaseous particles move at high velocity with negligible intermolecular forces of attraction between them.

A phase transition from liquid to gaseous state now represents the greatest change in the entropy of the system since gases posses the highest entropy among all the states of matter, hence the answer.

What type of reaction does this equation represent?

2I4O9(s) → 4I2(s) + 9O2(g)

Answers

Answer:

2I4O9_4I +9O

Explanation:

Complex compound (

I

4

O

9

) is broken down to form

I

2

and

O

2

Answer:

Decomposition

Explanation:

Because it went from one compound to two elements.

Identify the type of reaction in the following and define each of them. (i) Carbohydrates are broken down to form glucose. (ii) Tarnishing of copper. (iii) Heating of ferric oxide with aluminium powder. (iv) Blue colour of copper sulphate solution disappears when zinc dust is added to it. (v) Dilute sulphuric acid is adeed to sodium hydroxide solution .

Answers

Answer:

(i) hydrolysis; (ii) combination;  (iii) single replacement;  

(iv) single replacement; (v) double replacement

Explanation:

(i) Carbohydrates are broken down to form glucose

Carbohydrates must react with water to form glucose.

For example,

C₆H₁₁O₅-O-C₆H₁₁O₆ + H-O-H ⟶ 2C₆H₁₂O₆

       maltose                                          glucose

This is a hydrolysis reaction — the reaction of a compound in which a molecule of water breaks one or more bonds to form new substances.

The reaction is not a decomposition (a reaction in which a compound breaks down into two or more simpler substances), because two different molecules are involved.

(ii) Tarnishing of copper.

Cu + S ⟶ CuS

This is a combination or synthesis reaction — in which two or more substances combine to form a single new substance.

(iii) Heating of ferric oxide with aluminium powder

Fe₂O₃ + 2Al ⟶ Al₂O₃ + 2Fe

This is a single displacement or single replacement reaction — in which one element replaces another element in a compound.

Here, Al is replacing Fe in its oxide.

(iv) Blue colour of copper sulphate solution disappears when zinc dust is added to it

CuSO₄ + Zn ⟶ ZnSO₄  + Cu

This is a single displacement or single replacement reaction.

Here, Zn is replacing Cu in its sulfate.

(v) Dilute sulfuric acid is added to sodium hydroxide solution  

H₂SO₄ + 2NaOH ⟶ Na₂SO₄ + 2H₂O

2H⁺, SO₄²⁻ + 2Na⁺OH⁻ ⟶ 2Na⁺, SO₄²⁻ + 2H-OH

This is a double displacement or double replacement reaction — in which the positive and negative ions of two ionic compounds exchange places to form two new compounds.

The Na⁺ ions are replacing the H⁺ ions in the sulfuric, forming sodium sulfate and water,  

In an experiment, 125ml of H2 is collected over water at 27C and barometric pressure of 753 torr. the vapor pressure of water at 27C is 26.74 what is the partial pressure of H2?

Answers

Answer:

Partial pressure of H₂ = 0.9556 atm

Explanation:

Given:

Barometric pressure = 753 torr

Vapor pressure of water = 26.74 torr

FInd:

Partial pressure of H₂

Computation:

Partial pressure of H₂ = Barometric pressure - Vapor pressure of water

Partial pressure of H₂ = 733 - 26.74  

Partial pressure of H₂ = 726.26 torr

1 atm = 760 torr

So,

Partial pressure of H₂ = 726.26/760

Partial pressure of H₂ = 0.9556 atm

Which of the following is represented by the number of significant figures in a quantity? A) estimation B) precision C) accuracy D) scientific notation

Answers

Answer: the answer is B estimation

Explanation:

i just took a test

The one that is represented by the number of significant figures in a quantity is scientific notation. The correct option is D.

What is scientific notation?

Scientific notation is a method of expressing numbers that are either too large or too small to be written in decimal form.

In the United Kingdom, it is known as scientific form, standard index form, or standard form.

The proper scientific notation format is an x 10b, where an is a number or decimal number with an absolute value greater than or equal to one and less than ten, or 1 |a| 10. b is the power of ten required for scientific notation to be mathematically equivalent to the original number.

Scientific notation is represented by the number of significant figures in a number.

Thus, the correct option is D.

For more details regarding scientific notation, visit:

https://brainly.com/question/18073768

#SPJ2

Indicators change color when an acid and a base are mixed together. The change in color most likely indicates that a chemical change has occured. a physical change has occured. a new acid has been produced. a new base has been produced.

Answers

Answer:

a chemical change

Explanation:

a physical change is mostly identified even without indicators i.e candle wax about forming a new acid or base I guess we have to include a ph scale to ascertain since the salt can be acidic but not necessarily an acid

Answer: The answer is A, a chemical change has occurred

Explanation:

I’m just a jenious

The mass number of a chromium atom is 52 and it has 24 protons. How many neutrons does this atom have? 24 28 76 80

Answers

The number of protons and neutrons together makes the total atomic mass of the element. The atom of chromium has 28 neutrons. Thus, option b is correct.

What is an atomic mass?

An atomic mass is the property of an element that defines the number of protons and neutrons of the atom placed in a periodic table. The atomic mass is represented at the lower half of the atomic symbol.

The atomic mass is the sum of the neutrons and the protons that are held together in the nucleus of the atom as a concentrated mass. The atomic number is given as,

Atomic number = number of protons + number of neutrons

Given,

The atomic mass of chromium = 52

Number of protons = 24

Substituting values above:

52 = 24 + number of neutrons

number of neutrons = 52-24

= 28

Therefore, the number of neutrons of a chromium atom is 28.

Learn more about atomic mass here:

https://brainly.com/question/17067547

#SPJ6

Answer: option b, 28

distinguish between deliquescence and efflorescence. ​

Answers

Explanation:

Deliquescent substances are solids that absorb moisture from the atmosphere until they dissolve in the absorbed water and form solutions. Efflorescent: Efflorescent substances are solids that can undergo spontaneous loss of water from hydrated salts.

HELP ME OUT PLZ Today is the deadline

Answers

Answer:

Option (1)

Explanation:

When two or more substances are chemically combined in a fixed proportion of mass, substance formed is a compound.

Properties of a compound are different from the properties of the elements from which the compound is formed.

If Magnesium (Mg) is burned in the presence of Oxygen (O₂), Magnesium oxide (MgO) is formed.

Properties of MgO are different from Mg and O₂ because MgO is a COMPOUND.

Option (1) will be the answer.

What is meant by 1m length ​

Answers

Answer:

The metre is defined as the length of the path travelled by light in a vacuum in 1/299 792 458 of a second.

1 metre is a length. Position A + 1m = Position B

The solubility product constant at 25°C for AgI(s) in water has the value 8.3 × 10–17. Calculate ∆Grxn at 25°C for the process AgI(s) <--> Ag+(aq) + I– (aq) where [Ag+] = 9.1 × 10–9 and [I–] = 9.1 × 10–9. –91.7 kJ/mol +91.7 kJ/mol 0.0 kJ/mol –4.4 kJ/mol +4.4 kJ/mol

Answers

Answer:

+91.7 KJmol-1

Explanation:

Recall that ∆G= -RTlnK

Since ∆G in this case is ∆Grxn and K is the Ksp

Note that the Ksp is the solubility product (as shown by the reaction equation)

∆Grxn is the change in free energy for the reaction, in this case the ionization of the silver iodide into silver and iodide ions.

R= 8.314JK-1 and T =25°C +273 = 298 K (the centigrade temperature must be appropriately converted to its corresponding absolute absolute before proceeding with the calculation)

Hence we can substitute values accordingly;

∆Grxn = -(8.314 × 298 × ln 8.3×10^-17)

∆Grxn = +91.7 KJmol-1

If the pH of a weak acid solution is 2.500 and the solution has a concentration of 0.100M, what is the Ka of the weak acid HA?

Answers

Answer:

The Kₐ of the weak acid is 1.033×10⁻⁴

Explanation:

The dissociation of a weak acid in aqueous solution is limited to about 5 to 10%

The acid dissociation reaction is given as follows;

HA (aq) + H₂O (l) → H₃O⁺(aq) + A⁻ (aq)

Given that the pH = 2.5, we have

pH = -log₁₀[H₃O⁺] = 2.5

∴ [H₃O⁺] = 10^(-2.5) = 0.0031623

[tex]K_a = \dfrac{[H_3O^+][A^-]}{[HA]}[/tex]

Kₐ = [H₃O⁺][A⁻]/[HA] = (0.0031623^2)/(0.1 - 0.0031623) = 1.033×10⁻⁴

The acid dissociation constant, Kₐ for weak acid is very low as obtained

why the filament of bulb has high melting point​

Answers

Answer:

The filament of a bulb has a high melting point because of the heat generated inside the bulb.

Explanation:

When electricity is concentrating and run through a bulb, it starts to generate heat. Leave it on long enough and it will start to build up a lot of heat. Have you ever tried touching a light bulb when it has been all day? It's scorching to the skin.

Since electricity generates heat, the bulb's filament has to have a high melting point so it doesn't melt, destroy the bulb, and leave you light-less. If the filament has a high melting point, then it is able to withstand heat generated by electricity and provide you light.

Based on the information that is given, which atom in the table has the highest mass?

Answers

The question is incomplete, the complete question is;

Atom Number of protons Number of electrons Number of neutrons

1 39 39 52

2 40 40 50

3 39 39 54

4 40 40 51

Based on the information that is given, which atom in the table has the highest mass?

a. 1

b. 2

c. 3

d. 4

Answer:

c

Explanation:

The relative atomic mass is given as; number of protons + number of neutrons. If we take the relative atomic mass of each of the options;

1) 39 +52 = 91

2) 40+50 = 90

3) 39 + 54 = 93

4) 40 + 51 = 91

Thus 3 has the highest mass as seen above, hence the answer given.

What is the oxidation number of carbon in CO2

Answers

Answer: Since oxygen is in group 6 on the periodic table, its valency is  

2 −

and hence so is its oxidation number.

But there are 2 oxygen atoms for each carbon atom so the total negative charge due the oxygen is  

4 −

But since a molecule must have a net charge of zero in the free form, it implies that the oxidation number of the carbon atom must then be  

+ 4

Smaller particles in an atom are called ____________.

Answers

Answer:

[tex]\large \boxed{\sf subatomic \ particles}[/tex]

Explanation:

The smaller particles in an atom are called subatomic particles. Subatomic particles include electrons, protons, and neutrons.

how is impure copper refined by electrolysis

Answers

Answer:

By giving electricity to copper compound solution.

Explanation:

Electrolysis is one of the major way of refined copper. The copper containing solution has two electrodes.i) positive electrodes called anode. ii) negative electrodes called cathode. When electricity is pass into the copper containing solution electrolysis process is starts and impure copper is formed in anode and pure copper is formed in cathode.

So, We can get pure copper in cathode through electrolysis.

I Hope this will be helpful for you.

If this is helpful for you .Then choose this answer as brainliest answer.

Hope it helps.

If you have any query, feel free to ask.

12. Classify the following as conduction, convection or radiation. a. A steel mug kept near a stove becomes hot after some time. b. The metal handlebars of a bicycle are colder than plastic hand grips. c. Some people get sunburn when they go out in the sun for a long time. d. The paper kept above a candle flame starts burning after some time.

Answers

A - convection

B - conduction

C - radiation

D - convection

Other Questions
Accrual basis accounting recognizes ___ (equity/revenues/expenses) when the service or product is delivered and records ___ (revenues/expenses/liabilities) when ___ (incurred/paid) in order to adhere to the matching principle. Three candidates were running for president of a student council. Altogether, 1524 students cast a vote in the election. The second place candidate had 140 votes less than the winner, but 395 votes more than the last place candidate. What percentage of all the votes cast were received by the winner? (Round your answer to the nearest percent). What the answer now question correct answer fast Write a 500-word definition essay of contemporary art In the diagram below, which organelle is a ribosome, which combines amino acids and produces proteins? PQRS is a parallelogram. Find the values of a and b. Solve for the value of c, ifc= a + b. Angle G is a circumscribed angle of circle E. Circle E is shown. Line segments F E and D E are radii. A line is drawn to connect points F and D. Tangents F G and D G intersect at point G outside of the circle. Angles E B D and F D E have measures of x degrees. What is the measure of angle G, in terms of x? x + x x + 90 180 x 180 2x The Benton Youth Soccer Team has 20 players on the team, including reserves. Of these, three are goalies. Today, the team is having a contest to see which goalie can block the most number of penalty kicks. For each penalty kick, a goalie stands in the net while the rest of the team (including other goalies) takes a shot on goal, one at a time, attempting to place the ball in the net. How many penalty kicks must be taken to ensure that everyone has gone up against each of the goalies? How did the fear of communism impact Americans in the USA? Pease help me I was confused 1. What colony's founders believed that tolerance was a great virtue?A. GeorgiaB. PennsylvaniaC. Massachusettsb. Virginia (ANSWER ASAP) The table represents the multiplication of two binomials. What is the value of A? -3x -3x2 -5x -5x2 can you please help me with me. lyrics of that's what best friends do by jeiel in best friends in the world. Paige has 3 coats: a pink one, a red one, and a white one. She has a black scarf, a gray scarf and 1 set of white gloves. Determine the different combinations Paige has for staying warm if she always wears a coat, a scarf, and gloves. For your answer, list the total number of possibilities and all possible combinations she has. Which organisms develop gills from pharyngeal arches and later develop lungs to breathe on land? Les dije que noen voz fuerte porque los nios estn durmiendo.a) hablenb) hablan Questions:1. What do you notice about how the angles fit together around a point?2. What is the measure of a straight angle?3. Describe the relationship amoung the measure of the angles of ABC4. The triangle sum theorem states that forma ABC, m The southern Black Codes: (LO 1.1, 1.4, 1.5, 1.6, 2.1, 2.2, 2.6, 3.2, 3.4, 3.6) a) allowed the arrest on vagrancy charges of former slaves who failed to sign yearly labor contracts. b) allowed former slaves to testify in court against whites and to serve on juries. c) were some of the first laws adopted as part of Radical Reconstruction in 1867. d) were denounced by President Johnson and declared unconstitutional by the Supreme Court. e) pleased northerners because they saw that the rule of law was returning to the South. Determine the sum of the first ten terms of the geometric series -1 + 2 - 4 + 8 + ... Since viruses are typically 20-200nm in diameter.. what is the best microscope to view them?