a. Using your knowledge of viral replication, explain why SARS- CoV-2 is highly efficient at transmitting from person-to-person whilst highly pathogenic avian influenza virus H5N1 is not? b. SARS-CoV-2 has a multi-basic cleavage site whilst many other coronaviruses do not. Speculate as to what role this multi-basic cleavage site may play in viral pathogenesis. c. Describe a scenario by which i) SARS-CoV-2 and ii) H5N1 highly pathogenic avian influenza virus can spill over into the human population and how we can prevent this in the future. (5 marks)

Answers

Answer 1

A. There are several explanations for the great effectiveness of SARS-CoV-2 transmission compared to the weak transmission of the highly lethal avian influenza virus H5N1. It is easy for SARS-CoV-2 to spread from person to person because respiratory droplets, which are produced when coughing, sneezing or even talking, are the main mode of transmission.

B. The SARS-CoV-2 spike protein contains a multi-basic cleavage site that is essential for viral pathogenesis. Proteases found in human cells are able to recognize this cleavage site, which facilitates efficient cleavage and activation of the spike protein. The virus is able to enter host cells more easily thanks to the activated spike protein, which increases infectivity.

C. i. SARS-CoV-2 can spread to humans by zoonotic transmission, possibly starting in a reservoir of wildlife with an intermediate host such as bats enabling transmission to humans.

ii. In particular, at poultry farms or live bird markets, the highly dangerous avian influenza virus H5N1 can be transmitted to humans by direct contact with sick birds. Strict biosecurity practices should be implemented in poultry farms, bird populations should be regularly surveyed, chicken products should be handled and prepared safely, and avian influenza concerns should be better communicated to the general public must be communicated.

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Related Questions

The replication method for making tissue scaffolds is also know as?

Answers

The replication method for making tissue scaffolds is commonly known as bioprinting.

Bioprinting is a revolutionary technology used in tissue engineering to create three-dimensional structures known as tissue scaffolds. It involves the precise deposition of living cells, biomaterials, and growth factors layer by layer to build functional tissue constructs. Bioprinting utilizes specialized printers equipped with bioink cartridges containing cell-laden materials. The process begins with the design of a digital model or blueprint of the desired tissue structure, which is then converted into printer instructions. These instructions guide the bioprinter to deposit the bioink in a controlled manner, mimicking the natural architecture and organization of the target tissue. As the bioink is deposited, the living cells within it can adhere, proliferate, and differentiate, gradually forming mature tissue. Bioprinting offers several advantages, including the ability to create complex tissue structures with high precision, customization to match patient-specific requirements, and the potential for rapid fabrication. This technology holds great promise for regenerative medicine and has the potential to revolutionize the field by enabling the production of functional tissues and organs for transplantation and drug testing purposes.

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13. Which of the following represents the correct order of stages during Drosophila development?
Select one:
a.
zygote, syncytial blastoderm, cellular blastoderm, gastrula, larva, pupa, adult
b.
syncytial blastoderm, cellular blastoderm, zygote, gastrula, larva, pupa, adult
c.
zygote, larva, gastrula, pupa, syncytial blastoderm, cellular blastoderm, adult
d.
cellular blastoderm, syncytial blastoderm, zygote, gastrula, pupa, larva, adult
and.
zygote, cellular blastoderm, syncytial blastoderm, gastrula, larva, pupa, adult
14.The following protein represents an inductive signal for the creation of lens tissue:
Select one:
a.
FGF8
b.
BMP4
c.
crystalline
d.
all of the above
and.
a and b are correct
15.The following molecule acts as a paracrine factor:
Select one:
a.
wnt
b.
hedgehog
c.
Delta
d.
all of the above
and.
a and b are correct

Answers

14. The protein that represents an inductive signal for the creation of lens tissue is: c. crystalline.

15. The molecule that acts as a paracrine factor is: d. all of the above (a. wnt and b. hedgehog).

these are correct answers.

Crystalline is a protein involved in the development and function of the lens in the eye. It plays a crucial role in the formation of lens tissue during development.

Both Wnt and Hedgehog molecules are examples of paracrine factors. Paracrine signaling refers to the release of signaling molecules by one cell to act on nearby cells, affecting their behavior or gene expression. Both Wnt and Hedgehog molecules function as paracrine signals in various developmental processes and tissue homeostasis.

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About 70% of the salt in our diet typically comes from _______ a. meals prepared at home b. peanut butter, ketchup, mustard, and other condiments c. prepared or processed food from the grocery store or restaurants d. potato chips and similar salty/crunchy snacks

Answers

About 70% of the salt in our diet typically comes from prepared or processed food from the grocery store or restaurants. The correct option is c).

Processed and prepared foods from grocery stores or restaurants contribute to about 70% of the salt in our diet. These foods often contain high amounts of added salt for flavoring and preservation purposes.

Common examples include canned soups, frozen meals, deli meats, bread, and savory snacks. Additionally, condiments like ketchup, mustard, and salad dressings can also add significant salt content to our diet.

It is important to be mindful of our salt intake as excessive consumption can increase the risk of high blood pressure and other related health issues. Therefore, the correct option is c).

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Check my Axons that release norepinephrine (NE) are called adrenergic, while axons that release acetylcholine (ACH) are called Fill in the blank

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Axons that release acetylcholine (ACH) are called cholinergic. In the nervous system, different neurons release specific neurotransmitters to transmit signals across synapses. Axons that release norepinephrine (NE) are referred to as adrenergic, while axons that release acetylcholine (ACH) are called cholinergic.

Adrenergic neurons primarily utilize norepinephrine as their neurotransmitter. Norepinephrine is involved in regulating various physiological processes such as the fight-or-flight response, mood, attention, and arousal. Adrenergic pathways are important in the sympathetic division of the autonomic nervous system.

On the other hand, cholinergic neurons release acetylcholine as their neurotransmitter. Acetylcholine plays a crucial role in muscle contractions, memory, cognitive functions, and the parasympathetic division of the autonomic nervous system.

The classification of axons as adrenergic or cholinergic is based on the specific neurotransmitter they release. Adrenergic axons release norepinephrine, while cholinergic axons release acetylcholine. This classification helps in understanding the diverse functions and effects of these neurotransmitters in the body and their involvement in different pathways and systems within the nervous system.

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4. Discuss the reactions and events of glycolysis indicating substrates, products, and enzymes - in order! I did the first for you. Substrate Enzyme Product i. glucose hexokinase/glucokinase glucose-6-phosphate ii. iii. iv. V. vi. vii. viii. ix. X.

Answers

Glycolysis is a multistep process involving the breakdown of glucose into pyruvate for the generation of energy.

The steps involved in glycolysis are as follows:

1. Glucose → (enzyme hexokinase) → glucose-6-phosphate

2. Glucose-6-phosphate → (enzyme phosphoglucose isomerase) → Fructose-6-phosphate

3. Fructose-6-phosphate → (enzyme phosphofructokinase-1) → Fructose-1,6-bisphosphate

4. Fructose-1,6-bisphosphate → (enzyme aldolase) → Dihydroxyacetone phosphate (DHAP) and Glyceraldehyde-3-phosphate (G3P)

5. DHAP → (enzyme triose phosphate isomerase) → Glyceraldehyde-3-phosphate (G3P)

6. Glyceraldehyde-3-phosphate → (enzyme glyceraldehyde-3-phosphate dehydrogenase) → 1,3-bisphosphoglycerate

7. 1,3-bisphosphoglycerate → (enzyme phosphoglycerate kinase) → 3-phosphoglycerate

8. 3-phosphoglycerate → (enzyme phosphoglycerate mutase) → 2-phosphoglycerate

9. 2-phosphoglycerate → (enzyme enolase) → Phosphoenolpyruvate (PEP)

10. Phosphoenolpyruvate (PEP) → (enzyme pyruvate kinase) → Pyruvate

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Which of the following is a START codon? O O UAA UAG AUG о O AGA Which term refers to animals that maintain their body temperature by internal mechanisms? Oectotherms Opoikilotherms O homeotherms endotherms The central dogma states that... ODNA --> RNA --> polypeptide --> protein ORNA --> DNA --> protein O polypeptide --> protein --> DNA DNA --> RNA --> amino acid --> tRNA Saturated fatty acids... have only double bonds O have a mix of double and single bonds are in a ring-shaped structure have only single bonds Which is FALSE about fecundity? Species like house flies have high fecundity It is defined as the number of offspring an individual can produce over its lifetime O Species with high survivorship have high fecundity Species like humans have low fecundity A cell is in a solution where there is more solute in the solution than there is in the cell. This would be called a/an... Ohypertonic solution hypotonic solution O isotonic solution Onone of the above This type of bond would connect a glucose molecule to a galactose molecule. Phosophodiester linkage O Ester bond Glycosidic linkage Hydrogen bond Which of the following best describes the role of light in photosynthesis? It produces NADPH It splits ribulose bisphosphate into 2 PGAs It causes the CO2 to combine with hydrogen atoms It excites the electrons that leave chlorophyll molecules Enzymes... O are needed in large quantities because they are used up during catalysis are not very specific in their choice of substrates O make endergonic reactions proceed spontaneously O lower the activation energy of a reaction Which would NOT be part of a nucleotide? O Ribose sugar Adenine Phosphate Sulfide

Answers

The start codon is AUG. Endotherms is the term that refers to animals that maintain their body temperature by internal mechanisms. The central dogma states that DNA --> RNA --> polypeptide --> protein. Saturated fatty acids have only single bonds.

Species with high survivorship have high fecundity is false about fecundity. A hypertonic solution is a cell that is in a solution where there is more solute in the solution than there is in the cell. Glycosidic linkage would connect a glucose molecule to a galactose molecule. The role of light in photosynthesis is to excite the electrons that leave chlorophyll molecules. Enzymes lower the activation energy of a reaction. Sulfide would NOT be part of a nucleotide. A codon is a sequence of three nucleotides that encodes a specific amino acid or terminates translation. AUG is a codon that represents methionine, which is always the first amino acid in the protein chain. Therefore, it is the start codon. Thus, the correct answer is AUG.

Endotherms is a term that refers to animals that maintain their body temperature by internal mechanisms. These animals depend on their metabolism to generate heat to maintain a constant body temperature. Therefore, it is the correct answer.The central dogma describes the flow of genetic information within a biological system. The correct flow of the central dogma is DNA --> RNA --> polypeptide --> protein. Therefore, DNA is transcribed into RNA, which is translated into polypeptides and, ultimately, into proteins. Therefore, the correct answer is DNA --> RNA --> polypeptide --> protein.Saturated fatty acids have only single bonds. Therefore, it is the correct answer. An unsaturated fatty acid, on the other hand, contains one or more double bonds in the hydrocarbon chain.

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Explain how gene expression in eukaryotes is regulated by 2.1 acetyl groups, histone proteins and proteins containing bromodomains 2.2 methyl groups and DNA

Answers

Gene expression is the process of transforming the genetic information encoded in DNA into a functional gene product, such as RNA and protein.

Gene expression is precisely regulated in eukaryotic cells by several molecular mechanisms, including acetylation and methylation modifications of histone proteins and DNA, respectively, and proteins containing bromodomains that regulate chromatin remodeling.  

2.1 Acetyl Groups, Histone Proteins, and Proteins Containing Bromodomains Acetylation of histone proteins refers to the process of adding acetyl groups to lysine residues in the N-terminal tails of histone proteins.

2.2 Methyl Groups and DNA Methylation of DNA is a post-replicative modification that typically occurs at cytosine residues in the context of CpG dinucleotides.

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1. When you stand on a foam pad with eyes closed in a
BESS test, the primary sensory input for balance is ______ .
a. olfaction
b. vestibular
c. somatosensation
d. vision
2. Olfaction affects the accu

Answers

The BESS test:When standing on a foam pad with closed eyes in the BESS (Balance Error Scoring System) test, the primary sensory input for balance is somatosensation. This is defined as the body’s internal and external sensory systems that help control balance and movement.

The somatosensory system comprises cutaneous and proprioceptive receptors located in the skin, muscles, joints, and bones of the body.

Olfaction affects the accuracy of taste: Olfaction (sense of smell) affects the accuracy of taste. Olfaction and gustation (sense of taste) are interconnected senses that work together to produce the perception of flavor. While the tongue is responsible for detecting taste, the nose is responsible for identifying smells. These two senses work together to produce a complete picture of flavor.

When the olfactory system is damaged, the sense of taste may be compromised, making it difficult to distinguish between different flavors. For example, without olfaction, foods may taste bland, and it may be challenging to differentiate between salty, sweet, bitter, or sour tastes.Hence, we can conclude that somatosensation is the primary sensory input for balance in the BESS test, and olfaction affects the accuracy of taste.

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The quadrant method would work well for counting
bacteria growing in a petri dish in the lab.
True False

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The given statement "The quadrant method would work well for counting bacteria growing in a petri dish in the lab" is true. The quadrant method is a microscopic method for enumerating bacteria or other microorganisms that are present in a sample.

A microscope and a special slide with counting grids are used to count bacterial cells. A quadrant counting slide is a popular type of counting slide. It is a plastic slide with a grid that can be used to count cells or particles. A quadrant counting slide is divided into four quadrants, each of which is a different color or pattern. These quadrants assist in the counting process.

The quadrant counting method is particularly useful for counting bacteria on an agar plate. When bacteria are grown on an agar plate, the agar is typically divided into quadrants, and bacterial colonies are counted in each quadrant. To count bacteria using this method, the quadrants are traced onto a clear plastic sheet, and the colonies are counted in each quadrant.

The counts from each quadrant are then summed to obtain the total number of bacteria on the plate. This technique is quick and straightforward, and it may be used to count bacteria on several plates in a short amount of time. The answer is "True.

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Discussion Unit 22 A Describe the flow of air from the nose to the alveoli, name all structures in the pathway and one abnormal condition associated with it.

Answers

An abnormal condition associated with this pathway is asthma. Asthma is a chronic respiratory disorder characterized by inflammation and narrowing of the airways. This can lead to difficulty in breathing, wheezing, coughing, and chest tightness.

The flow of air from the nose to the alveoli involves several structures in the respiratory pathway. It begins with the inhalation of air through the nostrils or nasal passages. The air then passes through the following structures:

Nasal cavity: The nasal cavity is the hollow space behind the nose. It is lined with mucous membranes and contains structures called turbinates that help filter, warm, and moisten the air.

Pharynx: The pharynx, also known as the throat, is a muscular tube located behind the nasal cavity. It serves as a common passage for both air and food.

Larynx: The larynx, or voice box, is located below the pharynx. It contains the vocal cords and plays a role in speech production.

Trachea: The trachea, commonly known as the windpipe, is a tube that connects the larynx to the bronchi. It is lined with ciliated cells and cartilaginous rings, which help maintain its shape and prevent collapse.

Bronchi: The trachea branches into two bronchi, one leading to each lung. The bronchi further divide into smaller bronchioles, which eventually lead to the alveoli.

Alveoli: The alveoli are small air sacs located at the ends of the bronchioles. They are the primary sites of gas exchange in the lungs, where oxygen is taken up by the bloodstream, and carbon dioxide is released.

An abnormal condition associated with this pathway is asthma. Asthma is a chronic respiratory disorder characterized by inflammation and narrowing of the airways. This can lead to difficulty in breathing, wheezing, coughing, and chest tightness. In individuals with asthma, the airway inflammation and increased sensitivity to certain triggers result in the constriction of the bronchial tubes, making it harder for air to flow freely. Proper management and treatment of asthma are important to maintain normal airflow and prevent respiratory distress.

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Compare the functions of the nervous and endocrine systems in
maintaining homeostasis (IN SIMPLEST FORM)

Answers

The nervous system uses electrical impulses and neurotransmitters to quickly transmit signals, while the endocrine system relies on hormones to regulate bodily functions over a longer duration.

The nervous system and endocrine system work together to maintain homeostasis, which refers to the stable internal environment of the body. The nervous system coordinates rapid responses to changes in the external and internal environment, while the endocrine system regulates various bodily functions over a longer duration.

The nervous system uses electrical impulses and neurotransmitters to transmit signals between neurons and target cells. It allows for quick responses to stimuli and helps regulate processes such as muscle contraction, sensory perception, and coordination.

For example, when body temperature rises, the nervous system triggers sweating to cool down the body.

On the other hand, the endocrine system releases hormones into the bloodstream to target cells and organs throughout the body. Hormones are chemical messengers that regulate processes such as metabolism, growth and development, reproduction, and stress responses.

They act more slowly but have long-lasting effects. For instance, the endocrine system releases insulin to regulate blood glucose levels.

In summary, the nervous system enables rapid responses to stimuli through electrical impulses, while the endocrine system regulates bodily functions through the release of hormones, allowing for long-term homeostasis maintenance. Together, these systems ensure the body maintains a balanced and stable internal environment.

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1. What is the main difference between gymnoperms and angiosperms? What do they have in common? 2. You remove a cell from a four-cell embryo of a roundworm. Explain what you expect to happen. 3. Describe the life cycle of an insect with complete metamorphosis and provide an example. (3.5 marks)
4. Describe the excretory system of insects. (5 marks)

Answers

Here are some facts about plants and animals, including the differences between gymnosperms and angiosperms, the development of roundworms, the life cycle of insects, and the excretory system of insects. Therefore  

1. Gymnosperms: uncovered seeds, angiosperms: seeds in fruit.

2. Roundworms: each cell contains complete info, removing a cell = developmental defect.

3. Insect complete metamorphosis: egg-larva-pupa-adult.

4. Insect excretory system: Malpighian tubules, bladder, anus; efficient waste removal.

1. The main difference between gymnosperms and angiosperms is that gymnosperms have uncovered seeds, while angiosperms have seeds that are enclosed in a fruit. Gymnosperms also have pollen cones, while angiosperms have flowers. Both gymnosperms and angiosperms are vascular plants, which means they have xylem and phloem tissues. They also both reproduce by pollination and seed dispersal.

2. If you remove a cell from a four-cell embryo of a roundworm, the embryo will not develop into a complete organism. This is because each cell in the embryo contains all the information necessary to create a complete organism. If you remove a cell, you are essentially removing some of the information that is needed for development. The remaining cells will try to compensate for the missing information, but they will not be able to do so perfectly. This will result in a developmental defect, and the embryo will not develop into a complete organism.

3. The life cycle of an insect with complete metamorphosis has four stages: egg, larva, pupa, and adult. The egg is laid by the adult insect and hatches into a larva. The larva is a feeding stage and grows rapidly. When the larva is mature, it pupates. The pupa is a resting stage during which the insect undergoes metamorphosis. The adult insect emerges from the pupa and begins the cycle again.

An example of an insect with complete metamorphosis is the butterfly. The butterfly lays its eggs on a plant. The eggs hatch into caterpillars. The caterpillars eat leaves and grow rapidly. When the caterpillars are mature, they pupate. The pupae are attached to a plant or other surface. The adult butterflies emerge from the pupae and begin the cycle again.

4. The excretory system of insects is composed of Malpighian tubules, a bladder, and an anus. Malpighian tubules are blind sacs that are located near the junction of the digestive tract and the intestine. The tubules remove waste products from the blood and transport them to the bladder. The bladder stores the waste products until they are excreted through the anus.

The excretory system of insects is very efficient at removing waste products from the body. This is important for insects because they have a very high metabolic rate. A high metabolic rate produces a lot of waste products, so it is important for insects to have a way to remove these waste products quickly.

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Which of the following statement about genetic drift is true? a. Genetic drift can cause a population to adapt to its environment. b. Genetic drift cannot fix alleles in a population without the action of natural selection. c. Genetic drift is unbiased: the frequency of an allele in a population is equally likely to go up or down. d. When populations are large, genetic drift is not invoved in causing them to differentiate. e. Genetic drift causes non-random loss of alleles from a population.

Answers

Genetic drift is a mechanism of evolution that affects the genetic structure of populations. It refers to the random fluctuations in allele frequencies that occur due to chance events rather than natural selection. Genetic drift is more pronounced in small populations, where chance events can have a significant impact on the genetic composition of the population.

In response to your question, option (e) is true about genetic drift. Genetic drift causes non-random loss of alleles from a population. This is because genetic drift refers to random fluctuations in allele frequencies, which can lead to the loss of alleles from the population. This can occur due to various chance events, such as mutations, migrations, or the death of individuals carrying particular alleles.

Genetic drift can also result in the fixation of alleles in a population, whereby one allele becomes the only allele present in the population. This can occur in small populations where chance events can have a significant impact on the genetic composition of the population. In summary, genetic drift is an important mechanism of evolution that can cause random fluctuations in allele frequencies, leading to the loss or fixation of alleles in a population.

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When you eat enough carbs, your protein is spared
gluconeogenesis. What does this mean?

Answers

When you eat enough carbs, your protein is spared from gluconeogenesis. This implies that when carbohydrates are present in the diet, protein molecules are not broken down to produce glucose molecules.

Instead, carbohydrates are converted to glucose molecules, which meet the body's energy requirements. Gluconeogenesis is the procedure of generating glucose from non-carbohydrate sources such as amino acids from protein, lactate, and glycerol.

In the absence of adequate carbohydrate supplies, this process occurs as a means of replenishing blood glucose concentrations. When a person eats an adequate quantity of carbohydrates, the glucose molecules can be used for energy, and there is no need for protein breakdown to create glucose. This is crucial since protein breakdown can result in the loss of muscle tissue, which may lead to weakness, weight loss, and an increased risk of chronic disease.

In short, it implies that when the body is fed adequate carbohydrates, the protein in the diet is utilized for its designated role in the body, which includes tissue repair, muscle growth and maintenance, and other metabolic processes rather than being used for energy generation.

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During development: cells die or survive based on their receptor’s stickiness (affinity) to what?
B cells undergo this development process in what organ? T cells undergo this development process in what organ? Place the cells in the squares below based on whether they will survive or die during the development process. These can either be B cells or T cells as they both undergo this process in their respective organs.
After Development: Once part of the immune system as mature adaptive cells (i.e., survived development), Adaptive cells can be ACTIVATED based on their receptor specificity. Both B cells and T cells under the clonal selection process during activation, if they detect (stick to) their prospective antigens.

Answers

During development, cells die or survive based on their receptor's stickiness (affinity) to self-antigens.

B cells undergo this development process in the bone marrow, while T cells undergo this development process in the thymus.

Survive: B cells with receptors that do not recognize self-antigens, T cells with receptors that can recognize self-antigens but not too strongly.

Die: B cells with receptors that strongly recognize self-antigens, T cells with receptors that cannot recognize self-antigens.

After development, mature adaptive cells (both B cells and T cells) can be activated based on their receptor specificity. They undergo clonal selection, where they are activated if they detect (stick to) their prospective specific antigens. This activation leads to the proliferation and differentiation of the selected cells, resulting in an immune response tailored to the detected antigen.

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AR encodes for an androgen receptor. It is needed for cells to respond to androgen hormones and is located on X chromosome. The recessive nonsense mutation leads to complete androgen insensitivity syndrome leading to the body's loss of ability to use androgens. Consider this scenario; If a male (XY) is born with the nonsense mutation form of AR, (assume functional copy of SRY on their Y), with regard to sexual determination, would this individual express more female or male phenotypic characteristics and why?
Next, in a pedigree with this trait, what would be unusual about the pedigree and the affected individuals considering that this is an x-linked trait and is recessive?

Answers

In the given scenario, the male (XY) with the nonsense mutation form of AR would express more female phenotypic characteristics than male phenotypic characteristics. This is because androgen hormones are required for the development of male genitalia and secondary sexual characteristics.

Since the body would be unable to respond to androgens, male genitalia and secondary sexual characteristics would not develop. Thus, the individual would appear more feminine than masculine. Further, the pedigree of this trait would have an unusual pattern since it is an x-linked recessive trait. Typically, the trait would be more frequently seen in males since they only have one copy of the X chromosome.

However, in this case, since the trait results in a loss of male characteristics, affected individuals may be incorrectly classified as female. This may cause the trait to appear more frequently in females rather than males.

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Question 34 Method of treatment to help transplanted organs survive because it blocks the co-stimulation step required in B-cell activation A. Rapamycin B. Anti-CD3
C. Cyclosporin A
D. Mab-IgE
E. CTLA-4Ig
Question 35 The first immunoglobulin response made by the fetus is
A. IgG B. IgA C. IgM D. IgD E. all of the Ig's are synthesized at the same time Question 36 The most common test to diagnose lupus
A. the complement fixation test B. double gel diffusion C. RAST test D. microcytotoxcity test E. ANA test

Answers

Question 34: The correct answer is option A. Rapamycin

Question 35: The correct answer is option. C. IgM

Question 36: The correct answer is option. E. ANA test

Question 34:

Method of treatment that helps transplanted organs survive because it blocks the co-stimulation step required in B-cell activation is Rapamycin. It is used in the treatment of transplant rejection and is a macrocyclic lactone produced by Streptomyces hygroscopicus.The target protein of rapamycin is called mammalian target of rapamycin (mTOR), which is a serine/threonine protein kinase that regulates cell growth, division, and survival in eukaryotic cells. Rapamycin targets the immune system, particularly T cells, by preventing the activation and proliferation of immune cells by inhibiting the mTORC1 pathway. This drug has anti-proliferative and anti-inflammatory properties that inhibit the immune response to a foreign antigen. It blocks co-stimulatory signals that induce T cell activation. This makes it very useful in the prevention of organ transplant rejection.

Question 35:

The first immunoglobulin response made by the fetus is IgM. It is synthesized and secreted by the plasma cells of the fetus' liver, bone marrow, and spleen. IgM is a pentameric immunoglobulin that is the first antibody that is synthesized during fetal development. The primary function of IgM is to bind to and neutralize foreign antigens, making it critical for the immune system's initial response to an infection.

Question 36:

The most common test to diagnose lupus is the ANA (antinuclear antibody) test. This test detects antibodies that target the cell nuclei in the body's cells. The ANA test is not diagnostic of lupus, but it is a helpful tool to diagnose the disease along with other clinical and laboratory criteria. If the ANA test is positive, other tests, such as the anti-dsDNA, anti-Sm, anti-Ro/La, or anti-phospholipid antibody tests, may be performed to support the diagnosis of lupus.

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Which of the following is a characteristic of all members of the fungi kingdom? O prokaryotic O unicellular O heterotrophic O autotrophic 2 pts

Answers

The characteristic of all members of the fungi kingdom is that they are heterotrophic in nature. Therefore, the correct option is "O heterotrophic".

Fungi are eukaryotic organisms, and they have a separate kingdom in taxonomy, called the Fungi Kingdom.

Members of this kingdom can range from the microscopic, single-celled yeasts to the massive, multicellular fungi-like mushrooms, to the decomposing mycelium webs that sprawl across a forest floor. In their ecological roles, fungi can be decomposers, plant pathogens, mutualistic symbionts, and predators.

Heterotrophic means "feeding on other organisms" or "consumers."

Fungi belong to the category of heterotrophs because they do not produce their own food.

Rather than photosynthesize like plants, they acquire their nutrition by absorbing organic compounds and minerals from other organisms.

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1. How did Penicillin rupture the E. coli cells in the video? Or stated another way, what cellular target does the antibiotic attack and what is its mechanism of action? 2. Explain the bacterial cell wall structure and compare/contrast the Gram positive and Gram negative bacterial cell wall.
3. Will Penicillin act equally well on all types of bacteria? If you have answered yes, then explain why? If you have answered no, then which type of cell would be more susceptible to Penicillin? What is it about that one type of cell that allows penicillin to act more effectively??

Answers

1-By inhibiting this enzyme, penicillin prevents the proper formation of the cell wall, leading to weakened cell walls and ultimately the rupture of E. coli cells.

2-Gram-positive bacteria have a thick peptidoglycan layer that retains the crystal violet stain, while Gram-negative bacteria have a thinner peptidoglycan layer surrounded by an outer membrane.

3-Penicillin does not act equally well on all types of bacteria.

1. Penicillin primarily targets the bacterial cell wall. It inhibits the formation of peptidoglycan, a crucial component of the cell wall in bacteria. The cell wall provides structural support and protection to the bacterial cell. Penicillin binds to and inhibits the enzyme transpeptidase, also known as penicillin-binding protein (PBP), which is responsible for cross-linking the peptidoglycan strands during cell wall synthesis. By inhibiting this enzyme, penicillin prevents the proper formation of the cell wall, leading to weakened cell walls and ultimately the rupture of E. coli cells.

2. Bacterial cell walls can be broadly categorized into Gram-positive and Gram-negative based on their staining characteristics. Gram-positive bacteria have a thick peptidoglycan layer that retains the crystal violet stain, while Gram-negative bacteria have a thinner peptidoglycan layer surrounded by an outer membrane. In Gram-positive bacteria, the cell wall consists mainly of peptidoglycan, which forms a thick, continuous layer. It provides rigidity and structural support to the cell. In Gram-negative bacteria, the cell wall consists of a thin layer of peptidoglycan sandwiched between two lipid bilayers, forming an outer membrane. The outer membrane acts as an additional protective barrier and contains various proteins, lipopolysaccharides (LPS), and porins that regulate the passage of substances into and out of the cell.

3. Penicillin does not act equally well on all types of bacteria. Gram-positive bacteria are generally more susceptible to penicillin because their cell walls are primarily composed of peptidoglycan, which is the target of penicillin. The thick peptidoglycan layer in Gram-positive bacteria provides more binding sites for penicillin, allowing the antibiotic to have a greater inhibitory effect on cell wall synthesis.

In contrast, Gram-negative bacteria have a thinner peptidoglycan layer, and the presence of the outer membrane acts as an additional barrier for penicillin. The outer membrane limits the access of penicillin to the peptidoglycan layer, making Gram-negative bacteria less susceptible to the antibiotic.

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Organize the following scenarios in this order: Ecology of ecosystems – of communities – of populations – of organisms.
I. All biotic and abiotic factors interacting in one area.
II. A group of individuals of the same species that interact freely and mate.
III. Ability of a plant species to live in soils with a lot of copper (Cu).
IV. Populations of different species living and interacting in an area.
Select one:
a. I, II, III and IV
b. I, IV, II and III
c. II, I, IV and I
d. IV, I, II and III

Answers

The order of the given scenarios in their respective ecology is the following:1. Ecology of organisms2. Ecology of populations3. Ecology of communities4. Ecology of ecosystems.

The scenario that falls under Ecology of organisms is:

III. Ability of a plant species to live in soils with a lot of copper (Cu).The scenario that falls under Ecology of populations is:

II. A group of individuals of the same species that interact freely and mate.

The scenario that falls under Ecology of communities is:

IV. Populations of different species living and interacting in an area.

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Many females prefer to mate with territorial males and NOT with males that hold no territories. Why?

Answers

Females prefer mating with territorial males due to resource access, genetic superiority, parental care, and a competitive advantage, ensuring higher survival and reproductive success for themselves and their offspring.

The preference of females for mating with territorial males can be attributed to several factors, many of which are rooted in evolutionary biology and reproductive strategies. Here are some reasons why females may show a preference for territorial males:

Resource availability: Territorial males often have access to more resources within their territories, such as food, nesting sites, or shelter. By choosing a territorial male, females can gain access to these resources, which can enhance their own survival and the survival of their offspring.Good genes hypothesis: Territorial males may demonstrate higher genetic quality, indicating their ability to survive and succeed in acquiring and defending a territory. Females can benefit from mating with such males as it increases the likelihood of their offspring inheriting advantageous traits, including better disease resistance, physical prowess, or cognitive abilities.Parental care: Territorial males are more likely to invest in parental care, as they have a stake in protecting and providing for their offspring within their territories. By selecting a territorial male, females increase the chances of receiving support and assistance in raising their young, leading to higher survival rates for their offspring.Competitive advantage: Mating with a territorial male can also confer a competitive advantage to the female. Territorial males often engage in aggressive behaviors to defend their territories from other males, reducing the chances of infidelity and ensuring the offspring's paternity.

It's important to note that while these preferences may be observed in many species, including some primates and birds, mating preferences can vary across different animal groups, and not all females exhibit the same preferences. Additionally, social and ecological factors can influence the extent to which these preferences are expressed in a given population or species.

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If you had gotten a water sample from a pond, what kind of organisms might have been collected? Choose all that apply. Oclams and snails hydra mites Oplanaria QUESTION 15 An insect is not in the phlya arthropoda. O True O False 4 QUESTION 12 A sea fan can be categorized in the porifera pylum. O True A O False

Answers

If you had gotten a water sample from a pond, Oclams and snails, Hydra, mites, and Planaria are the kind of organisms that might have been collected.

Oclams and snails are part of the Mollusca phylum. Hydra and Planaria belong to the Cnidaria and Platyhelminthes phyla, respectively.

Mites belong to the Arthropoda phylum.An insect is not in the phylum Arthropoda. This statement is false.A sea fan cannot be categorized in the Porifera phylum. This statement is false. Sea fans belong to the Cnidaria phylum.

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Which of the following statements about viruses is FALSE? Viruses have a nucleus but no cytoplasm. а Viruses can reproduce only when they are inside a living host cell. Viruses cannot make proteins on their own. Some viruses use RNA rather than DNA as their genetic material.

Answers

The option that is untrue of the ones offered is "Viruses have a nucleus but no cytoplasm."

Acellular infectious organisms with a fairly straightforward structure are viruses. They are made up of genetic material, either DNA or RNA, that is encased in a protein shell called a capsid. A virus's outer envelope may potentially be derived from the membrane of the host cell.However, biological organelles like a nucleus or cytoplasm are absent in viruses. They lack the equipment needed to synthesise proteins or carry out autonomous metabolic processes. In place of doing these things themselves, viruses rely on host cells.

The remaining assertions made are accurate:

- Only when a virus is inside a living host cell can it proliferate. They use the host cell's biological machinery to stealthily copy their genetic material.

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Which sensory receptor provides instantaneous information about the amount of tension in a muscle Golgi Tendon organ Annulospiral receptor Muscle spindle Intrafusal fibers None of the included answers

Answers

The Golgi Tendon organ provides instantaneous information about the amount of tension in a muscle. Amount of tension in a muscle Golgi Tendon organ Annulospiral receptor Muscle spindle Intrafusal fibers None

The Golgi Tendon organ is a sensory receptor located within the tendons of muscles. It is responsible for detecting changes in muscle tension. When a muscle contracts, the tension on the tendon increases, and the Golgi Tendon organ senses this change. It then sends signals to the central nervous system to regulate muscle contraction and prevent excessive tension or damage. The Golgi Tendon organ provides instantaneous feedback about the amount of tension in a muscle, allowing for precise control of muscle contraction and movement.

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27.
Which of the following species lived at the same time as modern Homo sapiens? Homo habilis Homo floresiensis O Homo rudolfensis Australopithecus afarensis

Answers

Among the species listed, Homo habilis and Homo rudolfensis lived at the same time as modern Homo sapiens. Homo habilis, considered one of the earliest members of the Homo genus, lived approximately 2.1 to 1.5 million years ago. Homo rudolfensis, another early hominin species, existed around 1.9 to 1.8 million years ago.

On the other hand, Homo floresiensis, commonly known as the "Hobbit," lived relatively recently, between approximately 100,000 and 50,000 years ago. This species coexisted with Homo sapiens but went extinct before the present day.

Australopithecus afarensis, an earlier hominin species, lived from approximately 3.85 to 2.95 million years ago. It did not exist at the same time as modern Homo sapiens.

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organic chem need help
Of the following, which correctly uses curved arrows to display a possible step in a radical mechanism?

Answers

The correct answer that uses curved arrows to display a possible step in a radical mechanism is the fourth option, which shows a curved arrow from a bond to a radical: Option 4:

Explanation: Curved arrows are used to display the movement of an electron pair or a single electron in organic chemistry reactions. Radical mechanisms involve the formation of a radical intermediate and the subsequent reaction of the radical with another molecule.

In this type of mechanism, single electrons are involved, and therefore, curved arrows are used to represent the movement of a single electron.

correct way to draw a curved arrow in a radical mechanism is to start from the location of the single electron and show its movement to the location of the new bond that it forms.

For example, in option 4, the curved arrow starts from the single electron in the carbon radical and ends at the bond between carbon and hydrogen. This indicates the movement of the single electron from the radical to the hydrogen atom, forming a new bond.

Therefore, option 4 is the correct answer that uses curved arrows to display a possible step in a radical mechanism.

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Which of the following is NOT a function of the plasma
membrane?
Group of answer choices
It regulates which substances can enter or leave the cell.
It receives information from outside the cell and tr

Answers

Ansmits signals to the cell's interior. It provides structural support and shape to the cell. It synthesizes proteins for cellular processes.

The plasma membrane, also known as the cell membrane, is a vital component of all living cells. It is a selectively permeable barrier that surrounds the cell, separating its internal environment from the external environment. The primary function of the plasma membrane is to regulate the movement of substances into and out of the cell. It controls the entry and exit of ions, molecules, and nutrients, ensuring the maintenance of proper internal conditions necessary for cell function. Additionally, the plasma membrane is involved in cell signaling, as it receives external signals and transmits them to the cell's interior, allowing the cell to respond to its surroundings. The plasma membrane also plays a role in cell adhesion, cell recognition, and maintaining the cell's structural integrity.

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1. List sugar, galactose, and glucose in order of
efficiency of fementation. (Describe reasons as well)
2. How temperature can affect ethanol fermentation?

Answers

1. List sugar, galactose, and glucose in order of efficiency of fermentation along with their explanation:Galactose: Galactose is a monosaccharide, similar to glucose, that can be converted to glucose-1-phosphate before being used in glycolysis,

Galactose is converted into glucose-6-phosphate in the liver. The sugar, which is an epimer of glucose, is not a key sugar used in fermentation. The efficiency of fermentation of galactose is less than that of glucose.Glucose: Glucose is the primary fuel for glycolysis, and it has the highest efficiency of fermentation among sugars. Glucose, unlike other sugars, does not need to be converted into a different type of sugar before being used in glycolysis. Glucose is broken down into pyruvate, which is a critical product of glycolysis, during glycolysis. Glucose fermentation is highly efficient.

Sugar: Sugar is a disaccharide consisting of fructose and glucose molecules, which is hydrolyzed into glucose and fructose before being used in fermentation. As a result, fermentation efficiency is less than glucose.2. How temperature can affect ethanol fermentation?Ethanol fermentation, like other enzymatic reactions, is influenced by temperature. Fermentation's optimal temperature range is between 20°C and 35°C. Lower temperatures reduce enzyme activity, and hence fermentation rate, while higher temperatures can cause enzyme denaturation or destruction, which will prevent ethanol fermentation from occurring. Therefore, the temperature can affect the ethanol fermentation.

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A patient comes into the emergency room with appendicitis, in
significant pain and reporting numbness and tingling in her
extremities. A blood test indicates that plasma [HCO3-] is 19 mM
and PaCO2 is

Answers

A blood test indicating a plasma [HCO3-] (bicarbonate ion concentration) of 19 mM and PaCO2 (partial pressure of carbon dioxide in arterial blood) would suggest a condition known as respiratory acidosis.

Respiratory acidosis occurs when there is an increase in the level of carbon dioxide in the blood due to inadequate ventilation. This can happen in conditions such as pneumonia, chronic obstructive pulmonary disease (COPD), or in this case, possibly due to the pain and discomfort caused by appendicitis. When carbon dioxide levels increase, it combines with water in the blood to form carbonic acid (H2CO3), which dissociates into bicarbonate ions (HCO3-) and hydrogen ions (H+). The decrease in plasma bicarbonate concentration (19 mM) indicates a compensatory response by the kidneys to retain more bicarbonate ions to help buffer the excess hydrogen ions and restore pH balance. The symptoms of numbness and tingling in the extremities can be attributed to the effects of acidosis on the nervous system. Acidosis can lead to electrolyte imbalances and disturbances in nerve conduction, resulting in abnormal sensations in the extremities. The patient's condition requires immediate medical attention and appropriate treatment, which may involve addressing the underlying cause of respiratory acidosis, providing pain relief, and ensuring proper ventilation. Treatment may also involve administering intravenous fluids and medications to restore acid-base balance and improve respiratory function.

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True or False: A clear temporal relationship between exposure
and disease is an advantage of cross sectional studies.
Group of answer choices
A. True
B. False

Answers

The statement "a clear temporal relationship between exposure and disease is an advantage of cross sectional studies" is false.

A clear temporal relationship between exposure and disease is not an advantage of cross-sectional studies. Cross-sectional studies are observational studies that assess the relationship between exposure and disease at a specific point in time. They are designed to gather data on exposure and disease prevalence simultaneously, but they do not establish a temporal sequence between exposure and disease.

In cross-sectional studies, researchers collect data from a population or sample at a single time point, without following the participants over time. Therefore, they cannot determine the temporal sequence of events, such as whether the exposure preceded the disease or vice versa. Cross-sectional studies are mainly used to estimate disease prevalence, examine associations between exposure and disease, and generate hypotheses for further research.

To establish a clear temporal relationship between exposure and disease, longitudinal studies or experimental studies such as randomized controlled trials (RCTs) are typically conducted. Longitudinal studies follow participants over an extended period, allowing for the assessment of exposure status before the development of the disease outcome.

RCTs, on the other hand, involve random allocation of participants to different exposure groups, allowing researchers to observe the effects of exposure on disease development over time.

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